LIVIVO - Search results -

Search results

Result 1 - 10 of total 9772

Search options

Article: Mitochondrial dysfunction and quality control lie at the heart of subarachnoid hemorrhage.

Zhang, Jiatong / Zhu, Qi / Wang, Jie / Peng, Zheng / Zhuang, Zong / Hang, Chunhua / Li, Wei

2023 Volume 19, Issue 4, Page(s) 825–832

Abstract: The dramatic increase in intracranial pressure after subarachnoid hemorrhage leads to a decrease in cerebral perfusion pressure and a reduction in cerebral blood flow. Mitochondria are directly affected by direct factors such as ischemia, hypoxia, ... ...

Abstract	The dramatic increase in intracranial pressure after subarachnoid hemorrhage leads to a decrease in cerebral perfusion pressure and a reduction in cerebral blood flow. Mitochondria are directly affected by direct factors such as ischemia, hypoxia, excitotoxicity, and toxicity of free hemoglobin and its degradation products, which trigger mitochondrial dysfunction. Dysfunctional mitochondria release large amounts of reactive oxygen species, inflammatory mediators, and apoptotic proteins that activate apoptotic pathways, further damaging cells. In response to this array of damage, cells have adopted multiple mitochondrial quality control mechanisms through evolution, including mitochondrial protein quality control, mitochondrial dynamics, mitophagy, mitochondrial biogenesis, and intercellular mitochondrial transfer, to maintain mitochondrial homeostasis under pathological conditions. Specific interventions targeting mitochondrial quality control mechanisms have emerged as promising therapeutic strategies for subarachnoid hemorrhage. This review provides an overview of recent research advances in mitochondrial pathophysiological processes after subarachnoid hemorrhage, particularly mitochondrial quality control mechanisms. It also presents potential therapeutic strategies to target mitochondrial quality control in subarachnoid hemorrhage.
Language	English
Publishing date	2023-10-16
Publishing country	India
Document type	Journal Article ; Review
ZDB-ID	2388460-5
ISSN	1876-7958 ; 1673-5374
ISSN (online)	1876-7958
ISSN	1673-5374
DOI	10.4103/1673-5374.381493
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Article ; Online: Generalized geometric Lie algebra and its research

WANG Gen / LIANG Yuxia

Journal of Shanghai Normal University (Natural Sciences), Vol 52, Iss 3, Pp 327-

2023 Volume 331

Abstract: In order to explore the general extension meanings of Lie algebra， the generalized geometric Lie ... bracket and generalized geometric Lie algebra are constructed and their related properties are studied ... containing Lie algebra as a special case. The differential homeomorphism of vector field on manifolds under ...

Abstract	In order to explore the general extension meanings of Lie algebra， the generalized geometric Lie bracket and generalized geometric Lie algebra are constructed and their related properties are studied， containing Lie algebra as a special case. The differential homeomorphism of vector field on manifolds under generalized geometric Lie bracket is proved， and the result given by Lie bracket is improved.
Keywords	lie algebra ; generalized geometric lie bracket ; differential homeomorphism ; lie bracket ; vector field ; Science (General) ; Q1-390
Language	English
Publishing date	2023-06-01T00:00:00Z
Publisher	Academic Journals Center of Shanghai Normal University
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Lie symmetry analysis of the effects of urban infrastructures on residential property values.

Lin, Chien-Wen / Wang, Jen-Cheng / Zhong, Bo-Yan / Jiang, Joe-Air / Wu, Ya-Fen / Leu, Shao-Wei / Nee, Tzer-En

PloS one

2021 Volume 16, Issue 8, Page(s) e0255233

Abstract: ... in housing markets, we proposed a new kind of volatility measure for house prices utilizing the Lie symmetry ... that the mass transit systems and the public green lands possessed the infinitesimal generators of Lie point symmetries ... by hedonic pricing model, the Lie symmetry analysis of the Schrödinger equation approach developed herein was ...

Abstract	Due to the complexity of socio-economic-related issues, people thought of housing market as a chaotic nucleus situated at the intersection of neighboring sciences. It has been known that the dependence of house features on the residential property value can be estimated employing the well-established hedonic regression analysis method in teams of location characteristic, neighborhood characteristic and structure characteristic. However, to further assess the roles of urban infrastructures in housing markets, we proposed a new kind of volatility measure for house prices utilizing the Lie symmetry analysis of quantum theory based on Schrödinger equation, mainly focusing on the effects of transportation systems and public parks on residential property values. Based on the municipal open government data regularly collected for four cities, including Boston, Milwaukee, Taipei and Tokyo, and all spatial sampling sites were featured by United States Geological Survey (USGS) National Map, transportation and park were modelled as perturbations to the quantum states generated by the feature space in response to the environmental amenities with different spatial extents. In an attempt to ascertain the intrinsic impact of the location-dependent price information obtained, the similarity functions associated with the Schrödinger equation were considered to facilitate revealing the city amenities capitalizing into house prices. By examining the spatial spillover phenomena of house prices in the four cities investigated, it was found that the mass transit systems and the public green lands possessed the infinitesimal generators of Lie point symmetries Y2 and Y5, respectively. Compared statistically with the common performance criteria, including mean absolute error (MAE), mean squared error (MSE) and, root mean squared error (RMSE) obtained by hedonic pricing model, the Lie symmetry analysis of the Schrödinger equation approach developed herein was successfully carried out. The invariant-theoretical characterizations of economics-related phenomena are consonant with the observed residential property values of the cities internationally, ultimately leading to develop a new perspective in the global financial architecture.
MeSH term(s)	Algorithms ; Boston ; Cities ; City Planning ; Commerce ; Geography ; Housing/economics ; Models, Theoretical ; Tokyo
Language	English
Publishing date	2021-08-05
Publishing country	United States
Document type	Journal Article
ISSN	1932-6203
ISSN (online)	1932-6203
DOI	10.1371/journal.pone.0255233
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Book ; Online: Automatic Symmetry Discovery with Lie Algebra Convolutional Network

Dehmamy, Nima / Walters, Robin / Liu, Yanchen / Wang, Dashun / Yu, Rose

2021

Abstract: ... discretization for continuous groups. We propose to work with Lie algebras (infinitesimal generators) instead ... of Lie groups. Our model, the Lie algebra convolutional network (L-conv) can automatically discover ...

Abstract	Existing equivariant neural networks require prior knowledge of the symmetry group and discretization for continuous groups. We propose to work with Lie algebras (infinitesimal generators) instead of Lie groups. Our model, the Lie algebra convolutional network (L-conv) can automatically discover symmetries and does not require discretization of the group. We show that L-conv can serve as a building block to construct any group equivariant feedforward architecture. Both CNNs and Graph Convolutional Networks can be expressed as L-conv with appropriate groups. We discover direct connections between L-conv and physics: (1) group invariant loss generalizes field theory (2) Euler-Lagrange equation measures the robustness, and (3) equivariance leads to conservation laws and Noether current.These connections open up new avenues for designing more general equivariant networks and applying them to important problems in physical sciences
Keywords	Computer Science - Machine Learning ; Computer Science - Artificial Intelligence ; Mathematics - Group Theory
Subject code	512
Publishing date	2021-09-15
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Solving the initial value problem of ordinary differential equations by Lie group based neural network method.

Wen, Ying / Chaolu, Temuer / Wang, Xiangsheng

PloS one

2022 Volume 17, Issue 4, Page(s) e0265992

Abstract: To combine a feedforward neural network (FNN) and Lie group (symmetry) theory of differential ... of ordinary DEs (ODEs). Introducing the Lie group expressions of the solution, the trial solution of ODEs is ... This is easily solved using the Lie group and known symbolic or numerical methods without any network ...

Abstract	To combine a feedforward neural network (FNN) and Lie group (symmetry) theory of differential equations (DEs), an alternative artificial NN approach is proposed to solve the initial value problems (IVPs) of ordinary DEs (ODEs). Introducing the Lie group expressions of the solution, the trial solution of ODEs is split into two parts. The first part is a solution of other ODEs with initial values of original IVP. This is easily solved using the Lie group and known symbolic or numerical methods without any network parameters (weights and biases). The second part consists of an FNN with adjustable parameters. This is trained using the error back propagation method by minimizing an error (loss) function and updating the parameters. The method significantly reduces the number of the trainable parameters and can more quickly and accurately learn the real solution, compared to the existing similar methods. The numerical method is applied to several cases, including physical oscillation problems. The results have been graphically represented, and some conclusions have been made.
MeSH term(s)	Neural Networks, Computer
Language	English
Publishing date	2022-04-06
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0265992
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Exploring the mechanism of action of Qian Lie Xing Fang during the treatment of benign prostatic hyperplasia via network pharmacology and molecular dynamics simulation analyses.

Xiang, Jingjing / Li, Zefei / Wang, Chaoyang

Medicine

2023 Volume 102, Issue 42, Page(s) e35540

Abstract: ... with Qian Lie Xing Fang (QLXF) via the warming and tonifying of kidney yang, promotion of blood circulation ...

Abstract	This study aimed to explore the historical research progress on benign prostatic hyperplasia from the perspective of traditional Chinese medicine theory and the treatment of benign prostatic hyperplasia (BPH) with Qian Lie Xing Fang (QLXF) via the warming and tonifying of kidney yang, promotion of blood circulation, and clearing of meridians. First, network pharmacology analysis was used to screen and identify possible pathways for BPH treatment with QLXF. Subsequently, molecular docking analysis helped explore the mechanism of action by which the components of QLXF affected androgen receptor (AR) and type 5 phosphodiesterase inhibitor (PDE-5) levels. Targets for treatment with QLXF were identified from the online Mendelian inheritance in man and DisGeNET databases. BPH-related genes were identified using GeneCards and online Mendelian inheritance in man databases, and their intersection was used to construct a protein-protein interaction network analysis graph. Subsequently, gene ontology and Kyoto encyclopedia of genes and genomes (KEGG) pathway enrichment analyses were performed. The semiflexible docking of the ingredients of QLXF acting on the 2 targets was performed via molecular docking and molecular dynamics simulation, to elucidate the mechanism of action by which the active ingredients affect AR and PDE-5 levels further. This enabled us to explore the pattern of interactions between small active ingredient molecules, the target protein, and the stability after binding at the microscopic level. Gene ontology enrichment analysis showed that QLXF affected several processes, such as DNA transcription factor binding, kinase binding, protein homodimerization activity, protein structure domain-specific binding, and protein-coupled amine receptor activity in BPH patients. KEGG results showed that chemical carcinogenic reactive oxidative species and the JAK-STAT, Pl3k-Akt, FoxO, NF-κB, and other pathways were significantly enriched. Conducting molecular docking studies to investigate the interaction of active components from QLXF with AR and PDE-5, it was found that MOL002260 may possess the potential to inhibit PDE-5 activity, while MOL010578 may exhibit the capability to inhibit AR activity. QLXF is closely associated with various biological processes and KEGG signaling pathways related to BPH. The active ingredients of QLXF were investigated for their interactions with AR and PDE-5, with a primary focus on the small molecules MOL002260 and MOL010578.
MeSH term(s)	Humans ; Male ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Network Pharmacology ; Prostatic Hyperplasia/drug therapy ; Prostatic Hyperplasia/genetics ; Databases, Genetic ; Drugs, Chinese Herbal/pharmacology ; Drugs, Chinese Herbal/therapeutic use
Chemical Substances	Drugs, Chinese Herbal
Language	English
Publishing date	2023-10-20
Publishing country	United States
Document type	Journal Article
ZDB-ID	80184-7
ISSN	1536-5964 ; 0025-7974
ISSN (online)	1536-5964
ISSN	0025-7974
DOI	10.1097/MD.0000000000035540
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ua VI Zs.171: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Lie symmetry analysis of the effects of urban infrastructures on residential property values.

Chien-Wen Lin / Jen-Cheng Wang / Bo-Yan Zhong / Joe-Air Jiang / Ya-Fen Wu / Shao-Wei Leu / Tzer-En Nee

PLoS ONE, Vol 16, Iss 8, p e

2021 Volume 0255233

Abstract	Due to the complexity of socio-economic-related issues, people thought of housing market as a chaotic nucleus situated at the intersection of neighboring sciences. It has been known that the dependence of house features on the residential property value can be estimated employing the well-established hedonic regression analysis method in teams of location characteristic, neighborhood characteristic and structure characteristic. However, to further assess the roles of urban infrastructures in housing markets, we proposed a new kind of volatility measure for house prices utilizing the Lie symmetry analysis of quantum theory based on Schrödinger equation, mainly focusing on the effects of transportation systems and public parks on residential property values. Based on the municipal open government data regularly collected for four cities, including Boston, Milwaukee, Taipei and Tokyo, and all spatial sampling sites were featured by United States Geological Survey (USGS) National Map, transportation and park were modelled as perturbations to the quantum states generated by the feature space in response to the environmental amenities with different spatial extents. In an attempt to ascertain the intrinsic impact of the location-dependent price information obtained, the similarity functions associated with the Schrödinger equation were considered to facilitate revealing the city amenities capitalizing into house prices. By examining the spatial spillover phenomena of house prices in the four cities investigated, it was found that the mass transit systems and the public green lands possessed the infinitesimal generators of Lie point symmetries Y2 and Y5, respectively. Compared statistically with the common performance criteria, including mean absolute error (MAE), mean squared error (MSE) and, root mean squared error (RMSE) obtained by hedonic pricing model, the Lie symmetry analysis of the Schrödinger equation approach developed herein was successfully carried out. The invariant-theoretical characterizations of ...
Keywords	Medicine ; R ; Science ; Q
Subject code	720 ; 710
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	Public Library of Science (PLoS)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Lie symmetry analysis of the effects of urban infrastructures on residential property values

Chien-Wen Lin / Jen-Cheng Wang / Bo-Yan Zhong / Joe-Air Jiang / Ya-Fen Wu / Shao-Wei Leu / Tzer-En Nee

PLoS ONE, Vol 16, Iss

2021 Volume 8

Abstract	Due to the complexity of socio-economic-related issues, people thought of housing market as a chaotic nucleus situated at the intersection of neighboring sciences. It has been known that the dependence of house features on the residential property value can be estimated employing the well-established hedonic regression analysis method in teams of location characteristic, neighborhood characteristic and structure characteristic. However, to further assess the roles of urban infrastructures in housing markets, we proposed a new kind of volatility measure for house prices utilizing the Lie symmetry analysis of quantum theory based on Schrödinger equation, mainly focusing on the effects of transportation systems and public parks on residential property values. Based on the municipal open government data regularly collected for four cities, including Boston, Milwaukee, Taipei and Tokyo, and all spatial sampling sites were featured by United States Geological Survey (USGS) National Map, transportation and park were modelled as perturbations to the quantum states generated by the feature space in response to the environmental amenities with different spatial extents. In an attempt to ascertain the intrinsic impact of the location-dependent price information obtained, the similarity functions associated with the Schrödinger equation were considered to facilitate revealing the city amenities capitalizing into house prices. By examining the spatial spillover phenomena of house prices in the four cities investigated, it was found that the mass transit systems and the public green lands possessed the infinitesimal generators of Lie point symmetries Y2 and Y5, respectively. Compared statistically with the common performance criteria, including mean absolute error (MAE), mean squared error (MSE) and, root mean squared error (RMSE) obtained by hedonic pricing model, the Lie symmetry analysis of the Schrödinger equation approach developed herein was successfully carried out. The invariant-theoretical characterizations of economics-related phenomena are consonant with the observed residential property values of the cities internationally, ultimately leading to develop a new perspective in the global financial architecture.
Keywords	Medicine ; R ; Science ; Q
Subject code	720 ; 710
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	Public Library of Science (PLoS)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Conditional Lie-Bäcklund Symmetries and Differential Constraints of Radially Symmetric Nonlinear Convection-Diffusion Equations with Source.

Ji, Lina / Wang, Rui

Entropy (Basel, Switzerland)

2020 Volume 22, Issue 8

Abstract: A conditional Lie-Bäcklund symmetry method and differential constraint method are developed ... the admitted conditional Lie-Bäcklund symmetries (differential constraints) are identified. As a consequence ... surface equation of the admitted conditional Lie-Bäcklund symmetry. ...

Abstract	A conditional Lie-Bäcklund symmetry method and differential constraint method are developed to study the radially symmetric nonlinear convection-diffusion equations with source. The equations and the admitted conditional Lie-Bäcklund symmetries (differential constraints) are identified. As a consequence, symmetry reductions to two-dimensional dynamical systems of the resulting equations are derived due to the compatibility of the original equation and the additional differential constraint corresponding to the invariant surface equation of the admitted conditional Lie-Bäcklund symmetry.
Language	English
Publishing date	2020-08-08
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2014734-X
ISSN	1099-4300 ; 1099-4300
ISSN (online)	1099-4300
ISSN	1099-4300
DOI	10.3390/e22080873
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: The Modified Temptation Resistance Task: A Paradigm to Elicit Children's Strategic Lie-telling.

Wang, Lamei / Wang, Zhenlin

Journal of visualized experiments : JoVE

2018 , Issue 134

Abstract: ... children's strategic lie-telling behaviors. The reward of transgression was intended to be too tempting ... to resist, so that children's spontaneous lie-telling behavior in the presence of irreversible evidence due ... transgression, truth-telling or lie-telling behavior if the child peeked, and the strategic lie-telling behavior ...

Abstract	The protocol for the temptation resistance paradigm was designed to elicit 2- to 8-year-old children's strategic lie-telling behaviors. The reward of transgression was intended to be too tempting to resist, so that children's spontaneous lie-telling behavior in the presence of irreversible evidence due to the transgression could be observed. Conducted in a developmental psychology laboratory behind a one-way mirror and video recorded with a hidden camcorder, the protocol starts with a guessing game where the child is given three trials to guess the identities of hidden objects under an upside down cup. The experimenter gives hints in the first two trials to make sure the child "guess" them correctly. At the beginning of the final trial, the experimenter leaves the room briefly and asks the child not to peek under the cup. If the child could not resist the temptation and peeks, small particles previously filled in the cup would scatter on a grooved surface. Upon the experimenter's return, the child is asked if he/she has peeked. If he/she denies transgression contrary to the presence of the physical evidence, he/she is asked to explain why the particles are on the table. Three responses could be observed in the procedure, including the initial transgression, truth-telling or lie-telling behavior if the child peeked, and the strategic lie-telling behavior in the presence of the physical evidence.
MeSH term(s)	Child ; Child Behavior/psychology ; Child, Preschool ; Deception ; Female ; Humans ; Inhibition, Psychological ; Male ; Motivation
Language	English
Publishing date	2018-04-06
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Video-Audio Media
ZDB-ID	2259946-0
ISSN	1940-087X ; 1940-087X
ISSN (online)	1940-087X
ISSN	1940-087X
DOI	10.3791/57189
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

To top

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito