Article ; Online: Relationship between the serum creatinine concentrations of preterm neonates within 24 h of birth and their mothers before delivery.
Clinical and experimental nephrology
2023 Volume 28, Issue 4, Page(s) 293–299
Abstract: ... a regression equation to describe the relationship between n-sCr within 24 h of birth in preterm neonates and m ...
Abstract | Background: Neonatal serum creatinine (n-sCr) concentrations during the first few days of life have been reported to correlate with the maternal serum Cr (m-sCr) concentrations. We aimed to derive a regression equation to describe the relationship between n-sCr within 24 h of birth in preterm neonates and m-sCr before delivery, and to perform multiple regression analysis to identify factors related to n-sCr and the difference between n-sCr and m-sCr. Methods: We recruited preterm neonates who were treated at the University of the Ryukyus Hospital between March 2012 and October 2022. Patients with underlying diseases or conditions that might affect hemodynamics were excluded, as were patients whose n-sCr and m-sCr were not measured in pairs. A total of 278 cases were included in the analysis. Results: The median (interquartile range) gestational age, birth weight, n-sCr, and m-sCr were 33.9 weeks (32.0-35.1 weeks), 1901 g (1579-2284 g), 0.55 mg/dL (0.48-0.64 mg/dL), and 0.47 mg/dL (0.42-0.57 mg/dL), respectively. The regression equation derived was n-sCr = 0.092 + 0.970 × m-sCr (R Conclusions: We have obtained an approximate equation of n-sCr = 0.1 + m-sCr for preterm neonates. In addition, the high PW/BW ration may reduce the difference between n-sCr and m-sCr. |
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MeSH term(s) | Infant, Newborn ; Humans ; Female ; Pregnancy ; Infant ; Infant, Premature ; Birth Weight ; Creatinine ; Placenta ; Gestational Age |
Chemical Substances | Creatinine (AYI8EX34EU) |
Language | English |
Publishing date | 2023-12-23 |
Publishing country | Japan |
Document type | Journal Article |
ZDB-ID | 1338768-6 |
ISSN | 1437-7799 ; 1342-1751 |
ISSN (online) | 1437-7799 |
ISSN | 1342-1751 |
DOI | 10.1007/s10157-023-02435-w |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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