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  1. Book ; Online ; E-Book: Neuroimaging pharmacopoeia

    Ginat, Daniel Thomas / Small, Juan E. / Schaefer, Pamela W.

    2022  

    Author's details editors, Daniel Thomas Ginat, Juan E. Small, Pamela W. Schaefer
    Keywords Brain/Imaging ; Drug interactions
    Subject code 616.804754
    Language English
    Size 1 online resource (413 pages)
    Edition Second edition.
    Publisher Springer
    Publishing place Cham, Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 3-031-08774-7 ; 9783031087738 ; 978-3-031-08774-5 ; 3031087739
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online: Intraoperative Radiotherapy (IORT) - A New Frontier for Personalized Medicine as Adjuvant Treatment and Treatment of Locally Recurrent Advanced Malignancy

    Small, William / Small, William / Thomas, Tarita O.

    2019  

    Keywords Medicine ; Oncology ; IORT ; dosimetry ; physics ; radiobiology ; Intrabeam ; breast cancer ; head and neck cancer ; pancreas cancer ; brain metastasis
    Size 1 electronic resource (76 pages)
    Publisher Frontiers Media SA
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021231450
    ISBN 9782889457946 ; 288945794X
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Book: Neuroimaging pharmacopoeia

    Ginat, Daniel Thomas / Small, Juan E. / Schaefer, Pamela W.

    2015  

    Author's details Daniel Thomas Ginat ; Juan E. Small ; Pamela Whitney Schaefer ed
    Keywords Drugs ; Pharmeceuticals ; Toxicity ; MRI ; Imaging ; Neuroradiology
    Language English
    Size XVIII, 382 S. : zahlr. Ill., 254 mm x 178 mm
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book
    HBZ-ID HT018592878
    ISBN 978-3-319-12714-9 ; 3-319-12714-4 ; 9783319127156 ; 3319127152
    Database Catalogue ZB MED Medicine, Health

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  4. Article ; Online: Society for Women in Radiation Oncology Consensus Statement on Family and Medical Leave.

    Baniel, Claire Christine / Ponce, Sara Beltrán / Lichter, Katie E / Peters, Gabrielle W / Small, Christina / Seldon, Crystal / Nguyen, Katarina T / Khan, Amanda Farah / Thomas, Charles R / Small, William / Kahn, Jenna M / Olivier, Kenneth R / Masters, Adrianna Henson / Barry, Parul N / Pollom, Erqi L / Jagsi, Reshma

    International journal of radiation oncology, biology, physics

    2023  Volume 116, Issue 2, Page(s) 270–275

    MeSH term(s) Humans ; Female ; Radiation Oncology ; Medical Oncology ; Societies, Medical ; Consensus
    Language English
    Publishing date 2023-04-06
    Publishing country United States
    Document type Editorial
    ZDB-ID 197614-x
    ISSN 1879-355X ; 0360-3016
    ISSN (online) 1879-355X
    ISSN 0360-3016
    DOI 10.1016/j.ijrobp.2022.12.027
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Salivary S100 calcium-binding protein beta (S100B) and neurofilament light (NfL) after acute exposure to repeated head impacts in collegiate water polo players.

    Monroe, Derek C / Thomas, Elizabeth A / Cecchi, Nicholas J / Granger, Douglas A / Hicks, James W / Small, Steven L

    Scientific reports

    2022  Volume 12, Issue 1, Page(s) 3439

    Abstract: Blood-based biomarkers of brain injury may be useful for monitoring brain health in athletes at risk for concussions. Two putative biomarkers of sport-related concussion, neurofilament light (NfL), an axonal structural protein, and S100 calcium-binding ... ...

    Abstract Blood-based biomarkers of brain injury may be useful for monitoring brain health in athletes at risk for concussions. Two putative biomarkers of sport-related concussion, neurofilament light (NfL), an axonal structural protein, and S100 calcium-binding protein beta (S100B), an astrocyte-derived protein, were measured in saliva, a biofluid which can be sampled in an athletic setting without the risks and burdens associated with blood sampled by venipuncture. Samples were collected from men's and women's collegiate water polo players (n = 65) before and after a competitive tournament. Head impacts were measured using sensors previously evaluated for use in water polo, and video recordings were independently reviewed for the purpose of validating impacts recorded by the sensors. Athletes sustained a total of 107 head impacts, all of which were asymptomatic (i.e., no athlete was diagnosed with a concussion or more serious). Post-tournament salivary NfL was directly associated with head impact frequency (RR = 1.151, p = 0.025) and cumulative head impact magnitude (RR = 1.008, p = 0.014), while controlling for baseline salivary NfL. Change in S100B was not associated with head impact exposure (RR < 1.001, p > 0.483). These patterns suggest that repeated head impacts may cause axonal injury, even in asymptomatic athletes.
    MeSH term(s) Athletes ; Biomarkers/metabolism ; Brain Concussion/diagnosis ; Brain Concussion/etiology ; Brain Concussion/metabolism ; Female ; Humans ; Intermediate Filaments/metabolism ; Male ; S100 Calcium Binding Protein beta Subunit/metabolism ; Water Sports
    Chemical Substances Biomarkers ; S100 Calcium Binding Protein beta Subunit ; S100B protein, human
    Language English
    Publishing date 2022-03-02
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-022-07241-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: A Case of Heavily Pretreated HER2+ Colorectal Liver Metastases Responsive to Hepatic Arterial Infusion Chemotherapy.

    Beechinor, Ryan J / Abidalhassan, Mustafa F / Small, Deborah F / Hoang, Huong K / Lamba, Ramit / Loehfelm, Thomas W / Foster, Cameron C / Koontz, Michael Z / Kim, Edward Jae-Hoon / Cho, May / Gholami, Sepideh

    Clinical colorectal cancer

    2023  Volume 22, Issue 2, Page(s) 245–249

    MeSH term(s) Humans ; Infusions, Intra-Arterial ; Liver Neoplasms/drug therapy ; Liver Neoplasms/secondary ; Colorectal Neoplasms/drug therapy ; Colorectal Neoplasms/pathology ; Hepatic Artery/pathology ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Fluorouracil
    Chemical Substances Fluorouracil (U3P01618RT)
    Language English
    Publishing date 2023-02-24
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2112638-0
    ISSN 1938-0674 ; 1533-0028
    ISSN (online) 1938-0674
    ISSN 1533-0028
    DOI 10.1016/j.clcc.2023.02.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Editorial: Intraoperative Radiotherapy (IORT)-A New Frontier for Personalized Medicine as Adjuvant Treatment and Treatment of Locally Recurrent Advanced Malignancy.

    Thomas, Tarita O / Small, William

    Frontiers in oncology

    2018  Volume 8, Page(s) 234

    Language English
    Publishing date 2018-06-25
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2018.00234
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Adult Provisioning Influences Nestling Corticosterone Levels in Florida Scrub Jays (Aphelocoma coerulescens).

    Elderbrock, Emily K / Small, Thomas W / Schoech, Stephan J

    Physiological and biochemical zoology : PBZ

    2018  Volume 91, Issue 6, Page(s) 1083–1090

    Abstract: We studied Florida scrub jay (Aphelocoma coerulescens) nestlings to examine the relationship between parental feeding rates and levels of corticosterone (CORT), a metabolic and stress-related steroid hormone hypothesized to play a role in mediating ... ...

    Abstract We studied Florida scrub jay (Aphelocoma coerulescens) nestlings to examine the relationship between parental feeding rates and levels of corticosterone (CORT), a metabolic and stress-related steroid hormone hypothesized to play a role in mediating begging behavior. It has been documented that nutritional deficiency results in increased glucocorticoid levels in nestling birds. Further, previous studies have found that CORT levels of Florida scrub jay nestlings are negatively correlated with parental nest attendance and provisioning rates; however, the behavioral observations were made several days before the collection of samples to assess CORT levels. Few studies have investigated whether experience immediately before sampling impacts nestling glucocorticoid levels, especially in a free-living species. By monitoring parental activity at the nest before sample collection, we found that nestling CORT levels varied as a function of parental provisioning rate and the time since their last feed. However, counter to our predictions, higher provisioning rates and more recent feedings were associated with higher CORT levels in nestlings rather than lower CORT levels. These results suggest that some aspect of parental provisioning results in increased CORT levels in nestling Florida scrub jays.
    MeSH term(s) Animals ; Corticosterone/blood ; Female ; Maternal Behavior ; Nesting Behavior ; Songbirds/physiology
    Chemical Substances Corticosterone (W980KJ009P)
    Language English
    Publishing date 2018-09-26
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 1473845-4
    ISSN 1537-5293 ; 1522-2152
    ISSN (online) 1537-5293
    ISSN 1522-2152
    DOI 10.1086/700258
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Influence of corticosterone treatment on nestling begging in Florida scrub-jays (Aphelocoma coerulescens).

    Elderbrock, Emily K / Small, Thomas W / Schoech, Stephan J

    General and comparative endocrinology

    2018  Volume 259, Page(s) 213–222

    Abstract: Altricial young are dependent on adults for protection and food, and they display nutritional need by begging to elicit feeding from parents. Begging at high levels can be energetically expensive and attract predators; thus, an individual must balance ... ...

    Abstract Altricial young are dependent on adults for protection and food, and they display nutritional need by begging to elicit feeding from parents. Begging at high levels can be energetically expensive and attract predators; thus, an individual must balance its nutritional needs with these potential costs. Further, because a parent is limited in the amount of food it can provide, begging can contribute to both parent-offspring conflict and sibling-sibling competition. Many extrinsic and intrinsic factors may contribute to begging behavior. One intrinsic factor of interest is corticosterone (CORT), a metabolic hormone hypothesized to play a role in regulating a nestling's begging behavior. We investigated the hypothesis that increased exposure to CORT influences nestling begging behavior in an altricial species, the Florida scrub-jay (Aphelocoma coerulescens). We treated one nestling per treatment nest with a twice-daily dose of exogenous hormone via a CORT-injected waxworm, whereas a second individual received a vehicle-injected waxworm. We monitored individual nestling and adult behavior at all nests with the use of high-definition video cameras on several days during treatment. We found no difference in begging rate between CORT fed and vehicle fed nestlings within a treatment nest. Further, to determine whether CORT treatment had indirect effects on the entire brood, we monitored additional nests, in which nestlings were not manipulated. When treatment and controls were compared, overall begging rates of nestlings in treatment nests were greater than those in control nests. This result suggests that CORT treatment of an individual altered its behavior, as well as that of its siblings.
    MeSH term(s) Animals ; Birds ; Corticosterone/pharmacology ; Corticosterone/therapeutic use ; Female ; Nesting Behavior/physiology
    Chemical Substances Corticosterone (W980KJ009P)
    Language English
    Publishing date 2018--01
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 1851-x
    ISSN 1095-6840 ; 0016-6480
    ISSN (online) 1095-6840
    ISSN 0016-6480
    DOI 10.1016/j.ygcen.2017.12.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Sex differences in the long-term repeatability of the acute stress response in long-lived, free-living Florida scrub-jays (Aphelocoma coerulescens).

    Small, Thomas W / Schoech, Stephan J

    Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology

    2015  Volume 185, Issue 1, Page(s) 119–133

    Abstract: There is increasing evidence that individual differences in the physiological stress response are persistent traits in many animals. To test the hypothesis that the stress-induced CORT (SI-CORT) response is repeatable over the adult life span of Florida ... ...

    Abstract There is increasing evidence that individual differences in the physiological stress response are persistent traits in many animals. To test the hypothesis that the stress-induced CORT (SI-CORT) response is repeatable over the adult life span of Florida scrub-jays (Aphelocoma coerulescens), we sampled 32 male and 25 female free-living scrub-jays (aged 2-13 years) during a 9-year period (2004-2012). Each individual was sampled two to five times and samples were collected one or more years apart during the pre-breeding season (Jan-March). In addition, individuals sampled over the greatest time period (6-8 years) were analyzed separately to more closely assess long-term repeatability. SI-CORT was repeatable in females, but not males, when values were not corrected for confounding variables (agreement repeatability). However, when the year and time of day of sample collection were controlled (adjusted repeatability), SI-CORT was repeatable in both sexes. SI-CORT was also repeatable in the males and females sampled 6-8 years apart. Finally, baseline CORT levels of males, but not females, exhibited low but significant repeatability when adjusted for year. The results of this study demonstrate that differences in SI-CORT levels were repeatable within adult scrub-jays sampled up to 8 years apart. Further, the female SI-CORT response was more consistent between pre-breeding seasons than males, which may have resulted from males having higher SI-CORT plasticity in response to environmental conditions. These data support the hypothesis that the SI-CORT response of Florida scrub-jays develops before adulthood and persists throughout much, if not all, of their natural adult life span.
    MeSH term(s) Age Factors ; Animals ; Corticosterone/blood ; Enzyme-Linked Immunosorbent Assay ; Female ; Florida ; Hydrocortisone/blood ; Longitudinal Studies ; Male ; Passeriformes/physiology ; Radioimmunoassay ; Sex Characteristics ; Stress, Physiological/physiology
    Chemical Substances Corticosterone (W980KJ009P) ; Hydrocortisone (WI4X0X7BPJ)
    Language English
    Publishing date 2015-01
    Publishing country Germany
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 231245-1
    ISSN 1432-136X ; 0174-1578
    ISSN (online) 1432-136X
    ISSN 0174-1578
    DOI 10.1007/s00360-014-0866-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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