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  1. Article ; Online: Gender identity questionnaire for children: An alternative scoring approach reflecting a child's affirmed gender identity.

    Hoq, Monsurul / Lami, Francesca / Tollit, Michelle Anne / Pang, Kenneth C

    International journal of transgender health

    2022  Volume 24, Issue 2, Page(s) 127–131

    Language English
    Publishing date 2022-10-08
    Publishing country United States
    Document type Editorial
    ISSN 2689-5277
    ISSN (online) 2689-5277
    DOI 10.1080/26895269.2022.2129612
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Pursuing the SDG11 Targets

    Francesca Abastante / Isabella M. Lami / Marika Gaballo

    Sustainability, Vol 13, Iss 3858, p

    The Role of the Sustainability Protocols

    2021  Volume 3858

    Abstract: This paper is built on the following research questions: (i) What are the direct/indirect relationships between Sustainable Development Goal 11 (SDG11) and sustainability protocols? (ii) Could the sustainability protocols constitute a solution towards ... ...

    Abstract This paper is built on the following research questions: (i) What are the direct/indirect relationships between Sustainable Development Goal 11 (SDG11) and sustainability protocols? (ii) Could the sustainability protocols constitute a solution towards the achievement of SDG11? We underline that, on the one hand, the SDGs are guidelines to support the development of sustainable policies and thus address all elements that may affect them, and on the other hand, sustainability protocols are assessment tools to promote sustainability-conscious design while remaining focused on the built environment. In the Italian regulatory context, the paper highlights how this difference in terms of focus and scale means that they only overlap and mutually reinforce each other with regard to certain aspects, more related to energy and air pollution issues and less to the social aspects of sustainability. Even if there is not always a direct relationship between the evaluation criteria of the protocols and the indicators of SDG11, it is possible to conclude that the sustainability protocols can facilitate the achievement of the SDG11 targets, acting as a key for the implementation of sustainable cities and helping in structuring the process leading to sustainability in a broader framework.
    Keywords SDGs ; SDG11 indicators ; evaluation criteria and indicators ; sustainability of cities ; evaluation of urban sustainability ; Italy ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Subject code 690
    Language English
    Publishing date 2021-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: The "perfect" storm: Current evidence on pediatric inflammatory multisystem disease during SARS-CoV-2 pandemic.

    Lami, Francesca / Scalabrini, Ilaria / Lucaccioni, Laura / Iughetti, Lorenzo

    Acta bio-medica : Atenei Parmensis

    2020  Volume 91, Issue 3, Page(s) e2020034

    Abstract: Current data suggest that during the global pandemic of COVID 19 children are less affected than adults and most of them are asymptomatic or with mild symptoms. However, recently, cases of pediatric patients who have developed severe inflammatory ... ...

    Abstract Current data suggest that during the global pandemic of COVID 19 children are less affected than adults and most of them are asymptomatic or with mild symptoms. However, recently, cases of pediatric patients who have developed severe inflammatory syndrome temporally related to SARS-CoV-2 have been reported both in USA and Europe. These reports, although sharing features with other pediatric syndromes such as Kawasaki disease (KD), Kawasaki disease shock syndrome (KDSS), macrophage activated syndrome (MAS) and shock toxic syndrome (TSS), seem to outline a novel entity syndrome, characterized by cytokine storm with elevated inflammatory markers and typical clinical finding. Clinical characteristics are greater median age than KD, higher frequency of cardiac involvement and gastrointestinal symptoms, lower frequency of coronary anomalies. We report a summary of the current evidence about clinical features, pathogenesis, therapy strategies and outcome of this novel syndrome.
    MeSH term(s) Betacoronavirus ; Biomarkers/blood ; COVID-19 ; Child ; Coronavirus Infections/blood ; Coronavirus Infections/epidemiology ; Cytokines/blood ; Humans ; Mucocutaneous Lymph Node Syndrome/blood ; Mucocutaneous Lymph Node Syndrome/epidemiology ; Pandemics ; Pneumonia, Viral/blood ; Pneumonia, Viral/epidemiology ; SARS-CoV-2
    Chemical Substances Biomarkers ; Cytokines
    Keywords covid19
    Language English
    Publishing date 2020-09-07
    Publishing country Italy
    Document type Journal Article ; Review
    ZDB-ID 2114240-3
    ISSN 2531-6745 ; 0392-4203
    ISSN (online) 2531-6745
    ISSN 0392-4203
    DOI 10.23750/abm.v91i3.10360
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Longitudinal evaluation of endothelial markers in children and adolescents with familial hypercholesterolemia.

    Bruzzi, Patrizia / Predieri, Barbara / Madeo, Simona / Lami, Francesca / Iughetti, Lorenzo

    Acta bio-medica : Atenei Parmensis

    2021  Volume 92, Issue 5, Page(s) e2021343

    Abstract: Background and aim: Children with heterozygous familial hypercholesterolemia (heFH) are at risk of premature atherosclerosis. Aims of this study were: (a) to longitudinally evaluate the endothelial dysfunction, estimated through brachial flow mediated ... ...

    Abstract Background and aim: Children with heterozygous familial hypercholesterolemia (heFH) are at risk of premature atherosclerosis. Aims of this study were: (a) to longitudinally evaluate the endothelial dysfunction, estimated through brachial flow mediated dilation (FMD), as first sign of subclinical atherogenesis in a group of children and adolescents affected by heFH in comparison to normo-lipidemic controls, and (b) to identify predictive factors influencing the endothelial function and its development in the same cohort of patients.
    Methods: This is a prospective, longitudinal and cross-sectional study. Physical examination, plasma lipid profile and brachial artery FMD were measured at baseline and after follow-up.
    Results: At baseline, FMD did not differ between heFH children (n.24, median age 9.71) and controls (n. 24, median age 10.29) (7.67 ± 9.26 vs. 11.18 ± 7.28 %, p 0.09). Nevertheless, during follow-up (median length of lipid-lowering diet 4.52 years), FMD got worse in 54% of heFH subjects and its worsening correlated to the increasing of low-density lipoprotein cholesterol (r -0.21, p < 0.05). Moreover, being male (β -0.46, p 0.03), undergoing puberty (β -0.61, p 0.03) and increasing of body mass index standard deviation score (β -0.39, p 0.03) were identified as main independent predictor factors of FMD drop.
    Conclusions: During the first decades of life, not only hypercholesterolemia, but also clusters of pro-atherogenic conditions and their persistence, could affect the endothelial function and its trend. (www.actabiomedica.it).
    MeSH term(s) Adolescent ; Brachial Artery/diagnostic imaging ; Child ; Cross-Sectional Studies ; Endothelium, Vascular ; Humans ; Hyperlipoproteinemia Type II ; Male ; Prospective Studies
    Language English
    Publishing date 2021-11-03
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2114240-3
    ISSN 2531-6745 ; 0392-4203
    ISSN (online) 2531-6745
    ISSN 0392-4203
    DOI 10.23750/abm.v92i5.11074
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: The Capacity of Magnesium to Induce Osteoclast Differentiation Is Greatly Enhanced by the Presence of Zoledronate.

    Ricchiuto, Silvia / Palumbo, Rossella / Lami, Francesca / Gavioli, Francesca / Caselli, Lorenzo / Montanari, Monica / Zappavigna, Vincenzo / Anesi, Alexandre / Zanocco-Marani, Tommaso / Grande, Alexis

    Biology

    2023  Volume 12, Issue 10

    Abstract: Bisphosphonates (BPs) are successfully used to cure a number of diseases characterized by a metabolic reduction in bone density, such as Osteoporosis, or a neoplastic destruction of bone tissue, such as multiple myeloma and bone metastases. These drugs ... ...

    Abstract Bisphosphonates (BPs) are successfully used to cure a number of diseases characterized by a metabolic reduction in bone density, such as Osteoporosis, or a neoplastic destruction of bone tissue, such as multiple myeloma and bone metastases. These drugs exert their therapeutic effect by causing a systemic osteoclast depletion that, in turn, is responsible for reduced bone resorption. Unfortunately, in addition to their beneficial activity, BPs can also determine a frightening side effect known as osteonecrosis of the jaw (ONJ). It is generally believed that the inability of osteoclasts to dispose of inflamed/necrotic bone represents the main physiopathological aspect of ONJ. In principle, a therapeutic strategy able to elicit a local re-activation of osteoclast production could counteract ONJ and promote the healing of its lesions. Using an experimental model of Vitamin D3-dependent osteoclastogenesis, we have previously demonstrated that Magnesium is a powerful inducer of osteoclast differentiation. Here we show that, surprisingly, this effect is greatly enhanced by the presence of Zoledronate, chosen for our study because it is the most effective and dangerous of the BPs. This finding allows us to hypothesize that Magnesium might play an important role in the topical therapy of ONJ.
    Language English
    Publishing date 2023-09-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2661517-4
    ISSN 2079-7737
    ISSN 2079-7737
    DOI 10.3390/biology12101297
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  6. Article ; Online: Renal function assessment after embolization of vascular complications following partial nephrectomy.

    Novara, Giacomo / Lami, Valeria / Evangelista, Laura / Bartoletti, Paola / De Conti, Giorgio / Carletti, Filippo / Martino, Francesca Katiana / Betto, Giovanni / Zattoni, Fabio / Dal Moro, Fabrizio

    BJU international

    2023  Volume 133, Issue 1, Page(s) 46–48

    MeSH term(s) Humans ; Nephrectomy/adverse effects ; Embolization, Therapeutic ; Kidney ; Kidney Neoplasms/surgery
    Language English
    Publishing date 2023-09-06
    Publishing country England
    Document type Letter
    ZDB-ID 1462191-5
    ISSN 1464-410X ; 1464-4096 ; 1358-8672
    ISSN (online) 1464-410X
    ISSN 1464-4096 ; 1358-8672
    DOI 10.1111/bju.16164
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  7. Article ; Online: Supporting Resilient Urban Planning through Walkability Assessment

    Francesca Abastante / Isabella M. Lami / Luigi La Riccia / Marika Gaballo

    Sustainability, Vol 12, Iss 8131, p

    2020  Volume 8131

    Abstract: The urban planning and evaluation literature suggests that making a walkable city means creating a resilient and healthy city. In recent years, alternative mobility has been the subject of numerous studies, showing that the concept of urban walkability ... ...

    Abstract The urban planning and evaluation literature suggests that making a walkable city means creating a resilient and healthy city. In recent years, alternative mobility has been the subject of numerous studies, showing that the concept of urban walkability can be used as an additional support in planning resilient cities. Though researchers agree that walkability assessment has a positive impact on public space planning, it is still difficult to include the topic in planning strategies because of its novelty in the scientific debate. This paper will first review the literature on walkability assessment and then propose a multi-methodological assessment framework that fills the gaps in existing assessment methods. The multi-methodological assessment framework contributes to overcoming the idea that objective and subjective aspects are “not part of the same planning project.” Thanks to its combination of hard and soft methods, the assessment framework illustrated in this paper can consider physical and perceptual aspects simultaneously and represent them visually using Geographic Information Systems (GIS). It can thus provide easily readable results that can be applied in establishing guidelines for planning resilient cities.
    Keywords walkability ; walkability measure ; urban resilience ; quantitative ; qualitative and mixed models and methods ; urban planning ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Subject code 710
    Language English
    Publishing date 2020-10-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Questioning Low-Carbon Transition Governance

    Federica Rotondo / Francesca Abastante / Giancarlo Cotella / Isabella Maria Lami

    Sustainability, Vol 12, Iss 10460, p

    A Comparative Analysis of European Case Studies

    2020  Volume 10460

    Abstract: To achieve the international emission reduction targets, current researches underline the need to overcome the dominant techno-centric approaches to energy transition, in favor of analyses that explore in more detail those practices and organizational ... ...

    Abstract To achieve the international emission reduction targets, current researches underline the need to overcome the dominant techno-centric approaches to energy transition, in favor of analyses that explore in more detail those practices and organizational assets that play a role in favoring a transition towards a low-carbon society. In this light, the article focuses on governance practices and, in particular, on the different tools and actors involved across variable scales and temporalities. Drawing on the activities of the ERASMUS+ Strategic Partnership for Higher Education LOTUS (Locally Organized Transition of Urban Sustainable Spaces), a selection of European case studies is explored and compared in light of (i) the implemented actions in terms of energy production and efficiency measures, (ii) the legal framework and the origin of the funding and (iii) the number and type of involved actors and their partnerships. On this basis, the analysis outlines, from both a theoretical and a practical stand, a number of critical issues that characterize these episodes of energy transition governance. In particular, the authors reflect upon the interaction between energy measures and urban contexts, the need for synergies among government level and the emergence of new forms of partnership among public, private and third parties’ actors.
    Keywords energy transition ; governance ; low-carbon society ; comparative studies ; Europe ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Subject code 320
    Language English
    Publishing date 2020-12-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article: The "perfect" storm: Current evidence on pediatric inflammatory multisystem disease during SARS-CoV-2 pandemic

    Lami, Francesca / Scalabrini, Ilaria / Lucaccioni, Laura / Iughetti, Lorenzo

    Acta Biomed

    Abstract: Current data suggest that during the global pandemic of COVID 19 children are less affected than adults and most of them are asymptomatic or with mild symptoms. However, recently, cases of pediatric patients who have developed severe inflammatory ... ...

    Abstract Current data suggest that during the global pandemic of COVID 19 children are less affected than adults and most of them are asymptomatic or with mild symptoms. However, recently, cases of pediatric patients who have developed severe inflammatory syndrome temporally related to SARS-CoV-2 have been reported both in USA and Europe. These reports, although sharing features with other pediatric syndromes such as Kawasaki disease (KD), Kawasaki disease shock syndrome (KDSS), macrophage activated syndrome (MAS) and shock toxic syndrome (TSS), seem to outline a novel entity syndrome, characterized by cytokine storm with elevated inflammatory markers and typical clinical finding. Clinical characteristics are greater median age than KD, higher frequency of cardiac involvement and gastrointestinal symptoms, lower frequency of coronary anomalies. We report a summary of the current evidence about clinical features, pathogenesis, therapy strategies and outcome of this novel syndrome.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #761260
    Database COVID19

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  10. Article ; Online: Markers of Inflammation and Endothelial Dysfunction in Young Survivors from Acute Lymphoblastic Leukemia.

    Bruzzi, Patrizia / Bigi, Elena / Felici, Francesca / Lami, Francesca / Cano Garcinuno, Maria Del Carmen / Giovanni, Palazzi / Cellini, Monica / Predieri, Barbara / Iughetti, Lorenzo

    Journal of adolescent and young adult oncology

    2020  Volume 10, Issue 5, Page(s) 599–605

    Abstract: Purpose: ...

    Abstract Purpose:
    MeSH term(s) Adolescent ; Biomarkers ; Body Mass Index ; Cancer Survivors ; Carotid Intima-Media Thickness ; Child ; Female ; Humans ; Inflammation ; Male ; Precursor Cell Lymphoblastic Leukemia-Lymphoma ; Receptor for Advanced Glycation End Products ; Risk Factors ; Young Adult
    Chemical Substances Biomarkers ; Receptor for Advanced Glycation End Products
    Language English
    Publishing date 2020-11-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2607978-1
    ISSN 2156-535X ; 2156-5333
    ISSN (online) 2156-535X
    ISSN 2156-5333
    DOI 10.1089/jayao.2020.0114
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