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  1. Article ; Online: The 2019-2020 coronavirus pandemic in Italy: immunologic and cultural hurdles on the road to a cure.

    Virgilio, Edoardo

    The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases

    2020  Volume 24, Issue 3, Page(s) 270

    MeSH term(s) COVID-19 ; Coronavirus Infections/epidemiology ; Coronavirus Infections/immunology ; Coronavirus Infections/prevention & control ; Culture ; Disease Eradication ; Humans ; Italy/epidemiology ; Pandemics/prevention & control ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/immunology ; Pneumonia, Viral/prevention & control
    Keywords covid19
    Language English
    Publishing date 2020-05-06
    Publishing country Brazil
    Document type Letter
    ZDB-ID 2041400-6
    ISSN 1678-4391 ; 1413-8670
    ISSN (online) 1678-4391
    ISSN 1413-8670
    DOI 10.1016/j.bjid.2020.04.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The 2019–2020 coronavirus pandemic in Italy

    Virgilio, Edoardo

    immunologic and cultural hurdles on the road to a cure

    2020  

    Abstract: Currently, Italy is the country most seriously affected in the world by the coronavirus disease 2019 (COVID-19). As of 30 March 2020, our Government certified that 31% of the worldwide deaths were from Italy (11,591 out of 36,500 cases) with the highest ... ...

    Abstract Currently, Italy is the country most seriously affected in the world by the coronavirus disease 2019 (COVID-19). As of 30 March 2020, our Government certified that 31% of the worldwide deaths were from Italy (11,591 out of 36,500 cases) with the highest mortality rate (11.4%) compared the global rate of 4.7%. Over the last weeks, several Italian hospitals adhered to international experimental investigations on off-label drugs, such as tocilizumab, an anti-IL-6 receptor monoclonal antibody and remdesivir, a nucleotide analog originally used against Ebola virus disease, and artificial active immunization (vaccines creation). To our great surprise, in our country, minimal medical and community attention has been riveted on passive immunity (immunoglobulin therapy).
    Keywords coronavirus ; COVID ; pandemic ; Italy ; active immunization ; passive immunization ; covid19
    Language English
    Publishing country it
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Leiomyosarcoma of the rectum: A systematic review of recent literature.

    Annicchiarico, Alfredo / Montali, Filippo / Baldinu, Manuel / Casali, Lorenzo / Virgilio, Edoardo / Costi, Renato

    Journal of surgical oncology

    2023  Volume 129, Issue 2, Page(s) 365–380

    Abstract: Leiomyosarcomas (LMSs) are rare tumors originating from the muscular layer. We performed a literature review of cases of confirmed rectal leiomyosarcomas (rLMSs) to clarify the history of such an infrequent tumor arising at such an uncommon location. In ... ...

    Abstract Leiomyosarcomas (LMSs) are rare tumors originating from the muscular layer. We performed a literature review of cases of confirmed rectal leiomyosarcomas (rLMSs) to clarify the history of such an infrequent tumor arising at such an uncommon location. In this research local recurrence was related to poorly differentiated rLMS and no other association between recurrence and any criteria was found. Concerning overall survival (OS), rLMS patients developing recurrence presented shorter longevity compared with the group without.
    MeSH term(s) Humans ; Leiomyosarcoma/surgery ; Leiomyosarcoma/pathology ; Rectum/surgery ; Rectum/pathology ; Rectal Neoplasms/surgery ; Rectal Neoplasms/pathology ; Pelvis/pathology
    Language English
    Publishing date 2023-10-10
    Publishing country United States
    Document type Systematic Review ; Journal Article ; Review
    ZDB-ID 82063-5
    ISSN 1096-9098 ; 0022-4790
    ISSN (online) 1096-9098
    ISSN 0022-4790
    DOI 10.1002/jso.27481
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Montali, Filippo / Baldinu, Manuel / Annicchiarico, Alfredo / Virgilio, Edoardo / Costi, Renato

    Acta bio-medica : Atenei Parmensis

    2022  Volume 93, Issue S1, Page(s) e2022273

    Abstract: Amyand's hernia (AH) is a rare condition in which the appendix is found in the sac of an inguinal hernia. It occurs in only 1% of adult inguinal hernias. The herniated appendix can occasionally range varying degrees of acute inflammation up to neoplastic ...

    Abstract Amyand's hernia (AH) is a rare condition in which the appendix is found in the sac of an inguinal hernia. It occurs in only 1% of adult inguinal hernias. The herniated appendix can occasionally range varying degrees of acute inflammation up to neoplastic transformation. An appendiceal tumor can be rarely described inside the AH sac. We describe a case of gangrenous appendicitis in AH and offer a review of the literature on AH when presenting with appendicitis associated with appendiceal cancer. As of 2022, only nine cases of AH presenting with appendicitis associated with appendiceal cancer have been reported by the pertinent literature. In order of decreasing frequency, AH, AH-related appendicitis and AH-related appendicitis associated with appendiceal cancer are three rare conditions. Particular attention should be kept in each situation as diagnosis is achieved postoperatively most of the times.
    MeSH term(s) Adult ; Appendiceal Neoplasms/complications ; Appendiceal Neoplasms/pathology ; Appendicitis/complications ; Appendicitis/surgery ; Appendix/pathology ; Data Collection ; Hernia, Inguinal/complications ; Hernia, Inguinal/surgery ; Humans
    Language English
    Publishing date 2022-09-22
    Publishing country Italy
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 2114240-3
    ISSN 2531-6745 ; 0392-4203
    ISSN (online) 2531-6745
    ISSN 0392-4203
    DOI 10.23750/abm.v93iS1.13322
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Open surgical cholecystostomy under local anaesthesia as salvage therapy of acute cholecystitis during the 4th COVID-19 wave in Northern Italy: experience from a rural hospital.

    Montali, Filippo / Virgilio, Edoardo / Ballabeni, Lucia / Bignone, Maddalena / Rollo, Alessio / Costi, Renato

    Acta bio-medica : Atenei Parmensis

    2023  Volume 94, Issue S1, Page(s) e2023208

    Abstract: The COVID-19 pandemic outbreak delayed interventions of elective surgery worldwide. In Italy, the first western country to be affected, 410000 operations formerly planned were cancelled with the beginning of the first wave. Symptomatic cholelithiasis ... ...

    Abstract The COVID-19 pandemic outbreak delayed interventions of elective surgery worldwide. In Italy, the first western country to be affected, 410000 operations formerly planned were cancelled with the beginning of the first wave. Symptomatic cholelithiasis represents one of the most common, benign medical conditions in the world leading the affected patients to general surgeons'attention; in 0.5% of cases gallstones (symptomatic or not) can complicate with acute lithiasic cholecystitis (ALC) whose universally acknowledged treatment of choice is laparoscopic cholecystectomy. Delaying in surgery of ALC can increase the rate of complications like severe ALC, acute cholangitis and sepsis. The 4th wave of COVID 19 in Northern Italy induced further stress on the healthcare system. In fact, the occurrence of difficult communication and delays in ALC patients transfer between first and second level hospitals lead to the re-emergence of obsolete surgical procedures. In our rural hospital, in fact, a 92 years old patient affected with ALC and several comorbidities was treated with a successful emergency surgical procedure of transperitoneal cholecistostomy in lieu of a radiological transperitoneal approach. Such a choice was dictated by the absence of an interventional radiology unit in our hospital as well as the unavailability of patient transfer to our central referral hub (the hospital of Parma) due to hospital overcrowding secondary to the 4th wave of COVID 19 pandemic.
    MeSH term(s) Humans ; Aged, 80 and over ; Cholecystostomy/methods ; Cholecystitis/surgery ; Hospitals, Rural ; Salvage Therapy ; Anesthesia, Local ; Pandemics ; COVID-19 ; Cholecystitis, Acute/surgery ; Treatment Outcome ; Retrospective Studies
    Language English
    Publishing date 2023-07-24
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2114240-3
    ISSN 2531-6745 ; 0392-4203
    ISSN (online) 2531-6745
    ISSN 0392-4203
    DOI 10.23750/abm.v94iS1.13586
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Stercoral perforation with peritonitis: a very rare complication of faecaloma impacting the sigmoid colon.

    Radicchi, Benedetta / Baldinu, Manuel / Casali, Lorenzo / Costi, Renato / Virgilio, Edoardo

    ANZ journal of surgery

    2021  Volume 91, Issue 10, Page(s) 2229–2230

    MeSH term(s) Colon, Sigmoid/diagnostic imaging ; Colon, Sigmoid/surgery ; Fecal Impaction/complications ; Fecal Impaction/diagnostic imaging ; Humans ; Intestinal Perforation/diagnosis ; Intestinal Perforation/etiology ; Intestinal Perforation/surgery ; Peritonitis/diagnosis ; Peritonitis/etiology
    Language English
    Publishing date 2021-10-19
    Publishing country Australia
    Document type Letter ; Comment
    ZDB-ID 2050749-5
    ISSN 1445-2197 ; 1445-1433 ; 0004-8682
    ISSN (online) 1445-2197
    ISSN 1445-1433 ; 0004-8682
    DOI 10.1111/ans.17149
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Managing Focal Nodular Hyperplasia of the Liver: Surgery or Minimally-invasive Approaches? A Review of the Preferable Treatment Options.

    Virgilio, Edoardo / Cavallini, Marco

    Anticancer research

    2018  Volume 38, Issue 1, Page(s) 33–36

    Abstract: Background/aim: Focal nodular hyperplasia (FNH) is the second most common benign tumor of the liver. As of 2017, many clinical, radiological and surgical features have been largely documented. On the other hand, little is still known about the ... ...

    Abstract Background/aim: Focal nodular hyperplasia (FNH) is the second most common benign tumor of the liver. As of 2017, many clinical, radiological and surgical features have been largely documented. On the other hand, little is still known about the correlation of FNH with hepatocellular carcinoma, nor the preferable modality of treatment. Our aim was to elucidate the latter topic.
    Materials and methods: We investigated the pertinent literature available as of 2017 through four popular search engines (PubMed, Science Direct, Scopus and Google Scholar). Four main approaches were selected: conservative treatment, surgery, radiofrequency ablation (RFA) and transarterial embolization (TAE).
    Results: We found most works to be on conservative and surgical approaches. On the contrary, only one article has been published for RFA to date. Seventeen articles dealt with TAE.
    Conclusion: TAE currently represents the most cogent and successful alternative to surgery.
    MeSH term(s) Catheter Ablation ; Embolization, Therapeutic ; Focal Nodular Hyperplasia/surgery ; Focal Nodular Hyperplasia/therapy ; Humans ; Liver/pathology ; Liver/surgery
    Language English
    Publishing date 2018
    Publishing country Greece
    Document type Journal Article ; Review
    ZDB-ID 604549-2
    ISSN 1791-7530 ; 0250-7005
    ISSN (online) 1791-7530
    ISSN 0250-7005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Proposal of a Classification System for Adenocarcinoma Involving the Ileocecal Valve (Bauhin's Valve): A Retrospective Study of 689 Right Hemicolectomized Patients.

    Virgilio, Edoardo / Montali, Filippo / Costi, Renato / Cavallini, Marco

    Anticancer research

    2020  Volume 40, Issue 7, Page(s) 4053–4057

    Abstract: Background/aim: As of 2020, adenocarcinoma arising in the ileocecal valve (ICV-A) has been examined along with cecal and right colon cancer (RCC) under the collective heading "ileocecal" tumor. We propose a new classification system for this cancer.: ... ...

    Abstract Background/aim: As of 2020, adenocarcinoma arising in the ileocecal valve (ICV-A) has been examined along with cecal and right colon cancer (RCC) under the collective heading "ileocecal" tumor. We propose a new classification system for this cancer.
    Patients and methods: We retrospectively analyzed RCC patients from 2003 to 2019. The scheme was: i) Type I cancer for adenocarcinomas residing in ICV; ii) Type II, if they reside 1 to 5 mm from ICV; iii) Type III, 6 mm to 10 mm from ICV; iv) Type IV, at 1,1 to 5 cm; v) Type V, at more than 5 cm (ascending colon cancer).
    Results: Of 689 hemicolectomized patients, there were 91 (13.2%) Type I, 87 Type II (12.6%), 38 (5.5%) Type III, 157 (22.8%) Type IV and 314 (45.6%) Type V. Each type was associated with at least one clinicopathologic feature.
    Conclusion: ICV-A was classified into five types (I-V) according to the distance from ICV. Further studies are needed in order to corroborate our findings.
    MeSH term(s) Adenocarcinoma/classification ; Adenocarcinoma/pathology ; Adenocarcinoma/surgery ; Aged ; Cecal Neoplasms/classification ; Cecal Neoplasms/pathology ; Cecal Neoplasms/surgery ; Colectomy ; Colonic Neoplasms/classification ; Colonic Neoplasms/pathology ; Colonic Neoplasms/surgery ; Female ; Humans ; Ileocecal Valve/pathology ; Male ; Retrospective Studies
    Language English
    Publishing date 2020-07-03
    Publishing country Greece
    Document type Journal Article
    ZDB-ID 604549-2
    ISSN 1791-7530 ; 0250-7005
    ISSN (online) 1791-7530
    ISSN 0250-7005
    DOI 10.21873/anticanres.14402
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Omental torsion at the time of COVID-19 in Northern Italy: a case report of conservative management with a review of the pertinent literature.

    Montali, Filippo / Costi, Renato / Virgilio, Edoardo / Presicci, Cristina / Sartorio, Carlotta / Pedrazzini, Massimo

    Acta bio-medica : Atenei Parmensis

    2022  Volume 93, Issue S1, Page(s) e2022123

    Abstract: Background and aim: In middle-aged men, omental torsion (OT) can be a cause of acute abdomen.The right side of the omentum is longer, heavier and more mobile than the left one and, as a consequence, it can twist more easily on its vascular axis. ... ...

    Abstract Background and aim: In middle-aged men, omental torsion (OT) can be a cause of acute abdomen.The right side of the omentum is longer, heavier and more mobile than the left one and, as a consequence, it can twist more easily on its vascular axis. Consequently, OT localization in the lower right quadrant is more frequent, and therefore it can mimic acute appendicitis clinical onset.In most cases, OT is defined as "primary" in the absence of any other underlying pathologies, or,  rarely, "secondary", when caused by other intra-abdominal diseases such as inguinal hernia, tumors, cysts or post-surgical scarring. To date, clinical diagnosis of OT still remains a challenging one in a preoperative setting and most cases are diagnosed intraoperatively. If diagnosis is correctly achieved preoperatively by adequate imaging examinations, most patients presenting with OT do not undergo surgery anymore. Such considerations gain importance at the time of COVID 19 pandemic, where a conservative management and an early discharge may be preferred owing to in-hospital morbidity after abdominal surgery whenever surgery may be avoided.
    Methods and results: We present a case of an OT successfully treated in a non-operative manner during COVID-19 outbreak in Norhern Italy and offer a review of the literature that supports such a clinical attitude.  Conclusions:  OT preoperative diagnosis is challenging and is usually achieved by abdominal CT-scan. The suggested OT initial management is conservative, leaving a surgical approach, preferably by laparoscopy, for the 15% of cases not improving with a non-surgical approach.
    MeSH term(s) Appendicitis ; COVID-19 ; Conservative Treatment ; Humans ; Male ; Middle Aged ; Omentum/blood supply ; Omentum/pathology ; Omentum/surgery ; Peritoneal Diseases/diagnosis ; Peritoneal Diseases/surgery ; Torsion Abnormality/diagnosis ; Torsion Abnormality/pathology ; Torsion Abnormality/surgery
    Language English
    Publishing date 2022-04-14
    Publishing country Italy
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 2114240-3
    ISSN 2531-6745 ; 0392-4203
    ISSN (online) 2531-6745
    ISSN 0392-4203
    DOI 10.23750/abm.v93iS1.11903
    Database MEDical Literature Analysis and Retrieval System OnLINE

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