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Article: A Prospective Study of Prevalence and Impact of Sarcopenia on Short-term Mortality in Hospitalized Patients with Liver Cirrhosis.

Thyloor Kenchappa, Surakshith / Sharma, Samarth / Kumar, Mandhir / Ghuman, Samarjit S / Arora, Anil / Ranjan, Piyush

Journal of clinical and experimental hepatology

2023 Volume 13, Issue 6, Page(s) 946–954

Abstract: Background: Sarcopenia is common in chronic advanced liver disease and is associated with poor prognosis. There is paucity of Indian data regarding sarcopenia in chronic advanced liver disease & its impact on prognosis. The aim of this study was to ... ...

Abstract	Background: Sarcopenia is common in chronic advanced liver disease and is associated with poor prognosis. There is paucity of Indian data regarding sarcopenia in chronic advanced liver disease & its impact on prognosis. The aim of this study was to study the prevalence of sarcopenia in Indian patients with chronic advanced liver disease and its impact on morbidity and short-term mortality. Methods: Patients with chronic advanced liver disease were prospectively evaluated for the presence of sarcopenia using computerized tomography (CT) abdomen. The cross-sectional area of the right psoas muscle was measured at the third lumbar vertebra (L3) and the Psoas muscle index (PMI) was calculated. Sarcopenia was defined as PMI <295 mm Results: Of the 156 patients with chronic advanced liver disease, 74 (47.4%) patients had sarcopenia. Sarcopenia was more commonly seen in males (M: F = 61:13) and in patients with alcohol-related liver disease. There was a linear correlation (negative) between the PMI and severity of liver disease as assessed by Child-Pugh and model for end-stage liver disease (MELD) scores (r = -0.591 and -0.465, respectively). Patients with encephalopathy, ascites, and coagulopathy had higher prevalence of sarcopenia. On six months follow-up, sarcopenic patients had higher readmission rates (74.3% vs. 22%; Conclusion: Sarcopenia is seen in about half of the patients with chronic advanced liver disease. It is commoner in males, patients with alcoholic liver disease, and those with advanced liver disease. Patients with sarcopenia have worse prognosis, require more frequent hospitalization and it negatively impacts short-term survival.
Language	English
Publishing date	2023-05-10
Publishing country	India
Document type	Journal Article
ISSN	0973-6883
ISSN	0973-6883
DOI	10.1016/j.jceh.2023.05.001
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Non-traditional tools for predicting coronary artery disease.

Khurana, Rishabh / Yadav, Anurag / Buxi, T B S / Rawat, Kishan Singh / Ghuman, Samarjit S

The National medical journal of India

2023 Volume 35, Issue 5, Page(s) 261–265

Abstract: Background The traditional coronary calcium score (CCS) is a time-tested tool for the evaluation of coronary atherosclerosis and predictor of future cardiovascular events. Non-traditional tools can also have a value in predicting and detecting ... ...

Abstract	Background The traditional coronary calcium score (CCS) is a time-tested tool for the evaluation of coronary atherosclerosis and predictor of future cardiovascular events. Non-traditional tools can also have a value in predicting and detecting subclinical coronary artery disease (CAD). Methods We studied the role of CCS, the traditional CAD risk predictor, and the less-recognized, non-traditional risk factors, i.e. epicardial fat volume (EFV) and thoracic extracoronary calcium (ECC), to assess the degree of subclinical CAD. In this cross-sectional observational study, we included 950 Indian patients (suspected to have CAD). Coronary computed tomography angiography was performed. Estimation of CCS, EFV and thoracic ECC was done. Results A CCS of 0 was seen in 583 patients (61.4%). Of these, 492 patients had normal coronary angiogram but 91 patients had CAD. The median values of EFV were statistically significantly higher in the 'CAD present and CCS 0' group compared to the 'CAD absent and CCS 0' group (p<0.001). The presence of thoracic ECC involving at least a single site was seen in only 6 of these 91 patients. When both EFV and CCS were considered together for the detection of CAD, the sensitivity and negative predictive value (NPV) were improved compared to either of these in isolation. When ECC was taken together with CCS and EFV, no further improvement in sensitivity or NPV was observed. Conclusion The combined use of traditional CCS along with non-traditional EFV may guide us in better profiling cardiovascular risk and supplement the various traditional cardiovascular risk factors/scores.
MeSH term(s)	Humans ; Coronary Artery Disease/diagnostic imaging ; Coronary Artery Disease/epidemiology ; Calcium ; Cross-Sectional Studies ; Tomography, X-Ray Computed/adverse effects ; Predictive Value of Tests ; Coronary Angiography/adverse effects ; Coronary Angiography/methods ; Risk Factors
Chemical Substances	Calcium (SY7Q814VUP)
Language	English
Publishing date	2023-05-03
Publishing country	India
Document type	Observational Study ; Journal Article
ZDB-ID	645116-0
ISSN	0970-258X
ISSN	0970-258X
DOI	10.25259/NMJI_513_19
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Article ; Online: Radiological imaging in infiltrative hepatocellular carcinoma

Rosaiah Komirisetti / Tarvinder B S. Buxi / Mayank Goyal / Samarjit Singh Ghuman

Journal of Medical Evidence, Vol 3, Iss 1, Pp 78-

2022 Volume 79

Keywords	Medicine ; R
Language	English
Publishing date	2022-01-01T00:00:00Z
Publisher	Wolters Kluwer Medknow Publications
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Multicentric Fibrolamellar Hepatocellular Carcinoma

Mayank Goyal / Komerisetty Rozaih / Salil Bhargava / Swapnil Sheth / Samarjit Singh Ghuman / Tarvinder B. S. Buxi

Journal of Gastrointestinal and Abdominal Radiology, Vol 06, Iss 01, Pp 042-

A Rare Case Report

2023 Volume 046

Abstract: Multicentric fibrolamellar hepatocellular carcinoma has not been reported yet in the world as of our knowledge. A Medline search for the term “multicentric fibrolamellar HCC” did not return any results. To our knowledge, this is the first case report of ... ...

Abstract	Multicentric fibrolamellar hepatocellular carcinoma has not been reported yet in the world as of our knowledge. A Medline search for the term “multicentric fibrolamellar HCC” did not return any results. To our knowledge, this is the first case report of multi-centric fibrolamellar hepatocellular carcinoma (HCC). We present the case of a 22-year-old male patient who had complaints of epigastric pain for 1 month. His general physical examinations were normal. Computed tomography of the abdomen revealed multiple hyper-enhancing space-occupying lesions, one of which showed a central scar. The final diagnosis of the case was multicentric fibrolamellar HCC, which was biopsy proven.
Keywords	fibrolamellar hcc ; metastasis ; multicenteric ; Internal medicine ; RC31-1245 ; Diseases of the digestive system. Gastroenterology ; RC799-869
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	Thieme Medical and Scientific Publishers Pvt. Ltd.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Congenital Central Overinflation with Mainstem Bronchial Stenosis: Pre- and Postnatal Imaging and Outcome-Case Report and Brief Review of Literature.

Sheth, Swapnil / Ghuman, Samarjit S / Buxi, Tarvinder B S / Sud, Seema / Aggarwal, Satish Kumar / Sachdev, Anil

The Indian journal of radiology & imaging

2021 Volume 31, Issue 4, Page(s) 1031–1035

Abstract: Congenital overinflation of lung is underdiagnosed prenatally as the imaging features of the same are not well described. We describe a very rare case of central variety of congenital overinflation, secondary to right mainstem bronchial stenosis, not ... ...

Abstract	Congenital overinflation of lung is underdiagnosed prenatally as the imaging features of the same are not well described. We describe a very rare case of central variety of congenital overinflation, secondary to right mainstem bronchial stenosis, not previously described in our knowledge, which presented as an enlarged homogenous echogenic/hyperintense lung with cardio-mediastinal shift and was misdiagnosed as congenital pulmonary airway malformation (CPAM). We reviewed imaging features helpful in prenatal diagnosis of this condition on ultrasound and magnetic resonance imaging and discussed an approach for differential diagnosis. The congenital central overinflation may be considered in prenatal detected echogenic lung lesions with the absence of cysts or systemic arterial supply and presence of hypervascularity or dilated bronchi within the lesion.
Language	English
Publishing date	2021-11-30
Publishing country	Germany
Document type	Case Reports
ZDB-ID	605869-3
ISSN	0971-3026 ; 0970-2016
ISSN	0971-3026 ; 0970-2016
DOI	10.1055/s-0041-1739380
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Zs.A 430: Show issues

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Article: Multicentric Fibrolamellar Hepatocellular Carcinoma: A Rare Case Report

Goyal, Mayank / Rozaih, Komerisetty / Bhargava, Salil / Sheth, Swapnil / Ghuman, Samarjit Singh / Buxi, Tarvinder B. S.

Journal of Gastrointestinal and Abdominal Radiology

2022 Volume 06, Issue 01, Page(s) 42–46

Abstract	Multicentric fibrolamellar hepatocellular carcinoma has not been reported yet in the world as of our knowledge. A Medline search for the term “multicentric fibrolamellar HCC” did not return any results. To our knowledge, this is the first case report of multi-centric fibrolamellar hepatocellular carcinoma (HCC). We present the case of a 22-year-old male patient who had complaints of epigastric pain for 1 month. His general physical examinations were normal. Computed tomography of the abdomen revealed multiple hyper-enhancing space-occupying lesions, one of which showed a central scar. The final diagnosis of the case was multicentric fibrolamellar HCC, which was biopsy proven.
Keywords	fibrolamellar HCC ; metastasis ; multicenteric
Language	English
Publishing date	2022-08-15
Publisher	Thieme Medical and Scientific Publishers Pvt. Ltd.
Publishing place	Stuttgart ; New York
Document type	Article
ISSN	2581-9178
ISSN (online)	2581-9178
DOI	10.1055/s-0042-1753535
Database	Thieme publisher's database

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Article: Magnetic Resonance Defecography in Obstructive Defecation Syndrome: A Pictorial Review Imaging Findings and Impact on Surgical Management

Sud, Seema / Khurana, Rishabh / Agarwal, Brij B. / Buxi, Tarvinder B.S. / Ghuman, Samarjit S.

Indographics

2022 Volume 01, Issue 01, Page(s) 16–26

Abstract: Pelvic floor, a funnel-shaped muscular structure plays a significant role in bowel and bladder activities. Defecatory disorders result from the structural changes and functional disorders. Pelvic floor dysfunction affects 15% of multiparous women. It is ... ...

Abstract	Pelvic floor, a funnel-shaped muscular structure plays a significant role in bowel and bladder activities. Defecatory disorders result from the structural changes and functional disorders. Pelvic floor dysfunction affects 15% of multiparous women. It is being expected that after 30 years, there would be 45% rise in demand of pelvic floor imaging. After ruling out primary and secondary causes of constipation, diagnosis of obstructed defecation syndrome (ODS) is made. ODS is emerging as one of the important causes of constipation. As the symptoms are nonspecific and examination findings are frequently inaccurate, the clinical evaluation becomes a difficult task. Hence, various imaging modalities are becoming popular as an adjunct tool for the assessment of these disorders. Clinical management of ODS is based on the Constipation and Bowel Activity Score (CABA) and delineation of the pelvic floor anatomy. After defining the pelvic floor anatomy–based structural abnormality, day care ambulatory surgical procedure, that is, stapled transanal resection rectopexy (STARR), is offered to the patients of ODS. It provides significant relief to patients suffering from constipation and reduction in postoperative CABA score. This review discusses the role of magnetic resonance defecography imaging in ODS its impact on subsequent management.
Keywords	magnetic resonance defecography ; obstructed defecation syndrome ; constipation and bowel activity score
Language	English
Publishing date	2022-01-01
Publisher	Thieme Medical and Scientific Publishers Pvt. Ltd.
Publishing place	Stuttgart ; New York
Document type	Article
ISSN	2583-8229
ISSN (online)	2583-8229
DOI	10.1055/s-0042-1742576
Database	Thieme publisher's database

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Article ; Online: Congenital Central Overinflation with Mainstem Bronchial Stenosis

Swapnil Sheth / Samarjit S. Ghuman / Tarvinder B.S. Buxi / Seema Sud / Satish Kumar Aggarwal / Anil Sachdev

Indian Journal of Radiology and Imaging, Vol 31, Iss 04, Pp 1031-

Pre- and Postnatal Imaging and Outcome—Case Report and Brief Review of Literature

2021 Volume 1035

Abstract	Congenital overinflation of lung is underdiagnosed prenatally as the imaging features of the same are not well described. We describe a very rare case of central variety of congenital overinflation, secondary to right mainstem bronchial stenosis, not previously described in our knowledge, which presented as an enlarged homogenous echogenic/hyperintense lung with cardio-mediastinal shift and was misdiagnosed as congenital pulmonary airway malformation (CPAM). We reviewed imaging features helpful in prenatal diagnosis of this condition on ultrasound and magnetic resonance imaging and discussed an approach for differential diagnosis. The congenital central overinflation may be considered in prenatal detected echogenic lung lesions with the absence of cysts or systemic arterial supply and presence of hypervascularity or dilated bronchi within the lesion.
Keywords	bronchial stenosis ; congenital overinflation ; mri ; prenatal ; ultrasound ; Medical physics. Medical radiology. Nuclear medicine ; R895-920
Subject code	610
Language	English
Publishing date	2021-10-01T00:00:00Z
Publisher	Thieme Medical and Scientific Publishers Pvt. Ltd.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Congenital Central Overinflation with Mainstem Bronchial Stenosis: Pre- and Postnatal Imaging and Outcome—Case Report and Brief Review of Literature

Sheth, Swapnil / Ghuman, Samarjit S. / Buxi, Tarvinder B.S. / Sud, Seema / Aggarwal, Satish Kumar / Sachdev, Anil

Indian Journal of Radiology and Imaging

2021 Volume 31, Issue 04, Page(s) 1031–1035

Abstract	Congenital overinflation of lung is underdiagnosed prenatally as the imaging features of the same are not well described. We describe a very rare case of central variety of congenital overinflation, secondary to right mainstem bronchial stenosis, not previously described in our knowledge, which presented as an enlarged homogenous echogenic/hyperintense lung with cardio-mediastinal shift and was misdiagnosed as congenital pulmonary airway malformation (CPAM). We reviewed imaging features helpful in prenatal diagnosis of this condition on ultrasound and magnetic resonance imaging and discussed an approach for differential diagnosis. The congenital central overinflation may be considered in prenatal detected echogenic lung lesions with the absence of cysts or systemic arterial supply and presence of hypervascularity or dilated bronchi within the lesion.
Keywords	bronchial stenosis ; congenital overinflation ; MRI ; prenatal ; ultrasound
Language	English
Publishing date	2021-10-01
Publisher	Thieme Medical and Scientific Publishers Pvt. Ltd.
Publishing place	Stuttgart ; New York
Document type	Article
ZDB-ID	605869-3
ISSN	1998-3808 ; 0971-3026 ; 0970-2016
ISSN (online)	1998-3808
ISSN	0971-3026 ; 0970-2016
DOI	10.1055/s-0041-1739380
Database	Thieme publisher's database

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Zs.A 430: Show issues

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Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

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Article ; Online: CT appearance of gastrointestinal tract mucormycosis.

Ghuman, Samarjit Singh / Sindhu, Pendyala / Buxi, T B S / Sheth, Swapnil / Yadav, Anurag / Rawat, Kishan Singh / Sud, Seema

Abdominal radiology (New York)

2020 Volume 46, Issue 5, Page(s) 1837–1845

Abstract: Mucormycosis is a fungal infection caused by fungi of order mucorales. It is most commonly seen in patients with an impaired immune system due to any cause. Gastrointestinal mucormycosis is the least frequent type and may be a primary disease or a ... ...

Abstract	Mucormycosis is a fungal infection caused by fungi of order mucorales. It is most commonly seen in patients with an impaired immune system due to any cause. Gastrointestinal mucormycosis is the least frequent type and may be a primary disease or a feature of generalized mucormycosis. Angioinvasion is the hallmark feature of mucormycosis, leading to bowel infarction which is the responsible for the most common clinical complaint of pain, and is also responsible for most of the imaging findings in this disease. The stomach is most commonly involved organ in the gastrointestinal tract and pneumatosis and lack of gastric wall enhancement are the most common imaging findings. Areas of bowel wall thickening and/ or lack of enhancement are seen in small bowel mucor and perforation can occur due to ischemia. Colonic mucor can present with mural thickening, or complete lack of definition or 'disappearance' of bowel wall with associated air containing collections. Mucormycosis affecting the bowel has a high mortality rate and early recognition and intervention may improve patient outcomes significantly. It should be suspected in immunosuppressed patients with imaging findings of unexplained bowel ischemia, infarction and/or pneumatosis without any obvious visible vascular thrombus.
MeSH term(s)	Gastrointestinal Diseases/diagnostic imaging ; Humans ; Intestines ; Mucormycosis/diagnostic imaging ; Tomography, X-Ray Computed
Language	English
Publishing date	2020-11-10
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2839786-1
ISSN	2366-0058 ; 2366-004X
ISSN (online)	2366-0058
ISSN	2366-004X
DOI	10.1007/s00261-020-02854-3
Database	MEDical Literature Analysis and Retrieval System OnLINE

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