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  1. Article ; Online: Thyroidectomy without Radioiodine in Low-Risk Thyroid Cancer.

    Tulchinsky, Mark

    The New England journal of medicine

    2022  Volume 386, Issue 22, Page(s) 2153–2154

    MeSH term(s) Carcinoma, Papillary/surgery ; Humans ; Iodine Radioisotopes/therapeutic use ; Risk ; Thyroid Neoplasms/radiotherapy ; Thyroid Neoplasms/surgery ; Thyroidectomy
    Chemical Substances Iodine Radioisotopes
    Language English
    Publishing date 2022-06-01
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMc2204553
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Selective history of radioactive iodine in medicine: Inexactitudes no longer.

    Tulchinsky, Mark

    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

    2018  Volume 45, Issue 4, Page(s) 711–712

    MeSH term(s) Humans ; Iodine ; Radioisotopes ; Thyroid Neoplasms
    Chemical Substances Radioisotopes ; Iodine (9679TC07X4)
    Language English
    Publishing date 2018-09-06
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 632519-1
    ISSN 1532-2157 ; 0748-7983
    ISSN (online) 1532-2157
    ISSN 0748-7983
    DOI 10.1016/j.ejso.2018.06.038
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Re: Low-Dose Radioactive Iodine Ablation Is Sufficient in Patients With Small Papillary Thyroid Cancer Having Minor Extrathyroidal Extension and Central Lymph Node Metastasis (T3 N1a).

    Tulchinsky, Mark

    Clinical nuclear medicine

    2018  Volume 43, Issue 8, Page(s) 630

    MeSH term(s) Humans ; Iodine ; Iodine Radioisotopes ; Lymph Nodes ; Thyroid Cancer, Papillary ; Thyroid Neoplasms
    Chemical Substances Iodine Radioisotopes ; Iodine (9679TC07X4)
    Language English
    Publishing date 2018-05-15
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 197628-x
    ISSN 1536-0229 ; 0363-9762
    ISSN (online) 1536-0229
    ISSN 0363-9762
    DOI 10.1097/RLU.0000000000002050
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Papillary thyroid microcarcinoma and active surveillance.

    Tulchinsky, Mark

    The lancet. Diabetes & endocrinology

    2016  Volume 4, Issue 12, Page(s) 974

    Language English
    Publishing date 2016-12
    Publishing country England
    Document type Letter
    ISSN 2213-8595
    ISSN (online) 2213-8595
    DOI 10.1016/S2213-8587(16)30282-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Arteriography for Lower Gastrointestinal Hemorrhage: Clarity Needed in Defining Evidence Supporting Algorithm and Preceding Tests.

    Tulchinsky, Mark

    JAMA surgery

    2016  Volume 152, Issue 2, Page(s) 209

    MeSH term(s) Algorithms ; Angiography ; Gastrointestinal Hemorrhage ; Humans
    Language English
    Publishing date 2016-11-29
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2701841-6
    ISSN 2168-6262 ; 2168-6254
    ISSN (online) 2168-6262
    ISSN 2168-6254
    DOI 10.1001/jamasurg.2016.4250
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: In Comparing Diagnostic Accuracy of Ultrasound and Hepatobiliary Scintigraphy for Acute Cholecystitis, It Is Only Fair that Both Tests Are Done and Interpreted at a Comparable Skill Level.

    Tulchinsky, Mark

    The Journal of emergency medicine

    2016  Volume 50, Issue 3, Page(s) 507–508

    MeSH term(s) Cholecystitis/diagnostic imaging ; Female ; Humans ; Male ; Radionuclide Imaging ; Ultrasonography/instrumentation
    Language English
    Publishing date 2016-03
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 605559-x
    ISSN 0736-4679
    ISSN 0736-4679
    DOI 10.1016/j.jemermed.2012.08.038
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: The American College of Nuclear Medicine Guidance on Operating Procedures for a Nuclear Medicine Facility During COVID-19 Pandemic.

    Tulchinsky, Mark / Osmany, Saabry

    Clinical nuclear medicine

    2020  Volume 46, Issue 7, Page(s) 571–574

    Abstract: Abstract: The novel coronavirus 2 pandemic is causing widespread disruption in everyday life necessitating urgent and radical adaptations in operating procedures at nuclear medicine facilities. The potential for causing severe illness, COVID-19, calls ... ...

    Abstract Abstract: The novel coronavirus 2 pandemic is causing widespread disruption in everyday life necessitating urgent and radical adaptations in operating procedures at nuclear medicine facilities. The potential for causing severe illness, COVID-19, calls for strict observance of preventive measures aimed to mitigate the spread of the virus. The threat of COVID-19 is particularly serious as there is no vaccine and no specific antiviral therapy. Further complications are introduced by shortages of personal protective equipment for healthcare workers who have direct contact with patients and effective testing to identify infected patients, raising the need for delaying some testing and therapies. Certain vulnerable segments of the general population have been identified (advanced age and certain comorbidities), which should heighten further their preventive efforts. Therefore, this guidance is intended to be operationalized depending on a facility's specific needs and local disease prevalence.
    MeSH term(s) COVID-19/epidemiology ; Health Personnel ; Humans ; Nuclear Medicine ; Pandemics/prevention & control ; Personal Protective Equipment ; Practice Guidelines as Topic ; Societies, Medical ; United States
    Keywords covid19
    Language English
    Publishing date 2020-02-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 197628-x
    ISSN 1536-0229 ; 0363-9762
    ISSN (online) 1536-0229
    ISSN 0363-9762
    DOI 10.1097/RLU.0000000000003146
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Radiotheragnostics Paradigm for Radioactive Iodine (Iodide) Management of Differentiated Thyroid Cancer.

    Slonimsky, Einat / Tulchinsky, Mark

    Current pharmaceutical design

    2020  Volume 26, Issue 31, Page(s) 3812–3827

    Abstract: ... with remnant uptake concord (TRUC) method (aka Tulchinsky method) was developed to validate that a benign ...

    Abstract This review of radioactive iodide treatment (RAIT) extends from historical origins to its modern utilization in differentiated thyroid cancer (DTC). The principles embedded in the radiotheragnostics (RTGs) paradigm are detailed. The diverse approaches in current practice are addressed, and this broad variability represents a major weakness that erodes our specialty's trust-based relationship with patients and referring physicians. The currently developing inter-specialty collaboration should be hailed as a positive change. It promises to clarify the target-based terminology for RAIT. It defines RAIT of post total thyroidectomy (PTT), presumably benign thyroid as 'remnant ablation' (RA). 'Adjuvant treatment' (AT) referrers to RAIT of suspected microscopic DTC that is inherently occult on diagnostic imaging. RAIT directed at DTC lesion(s) overtly seen on diagnostic imaging is termed 'treatment of known disease' (TKD). It was recently recognized that a 'recurrent' DTC is actually occult residual DTC in the majority of cases. Thyroglobulin with remnant uptake concord (TRUC) method (aka Tulchinsky method) was developed to validate that a benign remnant in the post-thyroidectomy neck bed, as quantified by the RAI uptake, is concordant with a measured thyroglobulin (Tg) level at the time of the initial post-thyroidectomy evaluation. It allows recognition of occult residual DTC contribution to post-thyroidectomy Tg. Case examples demonstrate the application of the TRUC method for a logical selection of a specific RAIT category, using imaging-guided identification and management of RAI-avid versus RAI-nonavid residual DTC, i.e. the radiotheragnostics paradigm.
    MeSH term(s) Humans ; Iodides ; Iodine Radioisotopes ; Neoplasm Recurrence, Local ; Retrospective Studies ; Thyroglobulin ; Thyroid Neoplasms/diagnostic imaging ; Thyroid Neoplasms/radiotherapy
    Chemical Substances Iodides ; Iodine Radioisotopes ; Thyroglobulin (9010-34-8)
    Language English
    Publishing date 2020-05-21
    Publishing country United Arab Emirates
    Document type Journal Article ; Review
    ZDB-ID 1304236-1
    ISSN 1873-4286 ; 1381-6128
    ISSN (online) 1873-4286
    ISSN 1381-6128
    DOI 10.2174/1381612826666200605121054
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Spotlight on the Association of Radioactive Iodine Treatment With Cancer Mortality in Patients With Hyperthyroidism is Keeping the Highest Risk From Antithyroid Drugs in the Blind Spot.

    Tulchinsky, Mark / Brill, A Bertrand

    Clinical nuclear medicine

    2019  Volume 44, Issue 10, Page(s) 789–791

    Abstract: July 1, 2019, JAMA Internal Medicine released online an article authored by Kitahara et al entitled "Association of radioactive iodine treatment with cancer mortality in patients with hyperthyroidism." The Altmetric Attention Score, a global indicator of ...

    Abstract July 1, 2019, JAMA Internal Medicine released online an article authored by Kitahara et al entitled "Association of radioactive iodine treatment with cancer mortality in patients with hyperthyroidism." The Altmetric Attention Score, a global indicator of interest from lay public and colleagues, skyrocketed to 223 by July 7, placing the article in the top 5% of all scored reports. The overall perception of death from cancer risk associated with I is inflated and not supported by evidence. As co-authors of this article, we offer previously unpublished data and analysis that (1) disputes clinical significance of the associated risk from I and (2) shows, again, that antithyroid drugs carry a statistically significant and a much more obvious cancer death risk.
    MeSH term(s) Antithyroid Agents/therapeutic use ; Humans ; Iodine Radioisotopes/therapeutic use ; Neoplasms/complications ; Neoplasms/mortality ; Neoplasms/therapy ; Thyroid Neoplasms/complications ; Thyroid Neoplasms/mortality ; Thyroid Neoplasms/therapy
    Chemical Substances Antithyroid Agents ; Iodine Radioisotopes ; Iodine-131
    Language English
    Publishing date 2019-07-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 197628-x
    ISSN 1536-0229 ; 0363-9762
    ISSN (online) 1536-0229
    ISSN 0363-9762
    DOI 10.1097/RLU.0000000000002792
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: SPECT/CT unequivocally depicts dilated cystic duct sign on hepatobiliary scintigraphy in acute cholecystitis.

    Tulchinsky, Mark

    Clinical nuclear medicine

    2013  Volume 38, Issue 2, Page(s) 149–152

    Abstract: The dilated cystic duct sign (DCDS) on hepatobiliary scintigraphy can lead to a false-negative test in patients with acute cholecystitis. Presented is a case of acute gangrenous cholecystitis with probable DCDS on the planar study that was unequivocally ... ...

    Abstract The dilated cystic duct sign (DCDS) on hepatobiliary scintigraphy can lead to a false-negative test in patients with acute cholecystitis. Presented is a case of acute gangrenous cholecystitis with probable DCDS on the planar study that was unequivocally delineated on SPECT/CT imaging. SPECT/CT may be useful when planar findings suggest DCDS.
    MeSH term(s) Aged ; Biliary Tract/diagnostic imaging ; Cholecystitis, Acute/diagnostic imaging ; Cholecystitis, Acute/pathology ; Cystic Duct/diagnostic imaging ; Cystic Duct/pathology ; False Negative Reactions ; Female ; Humans ; Liver/diagnostic imaging ; Multimodal Imaging ; Positron-Emission Tomography ; Tomography, X-Ray Computed
    Language English
    Publishing date 2013-02
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 197628-x
    ISSN 1536-0229 ; 0363-9762
    ISSN (online) 1536-0229
    ISSN 0363-9762
    DOI 10.1097/RLU.0b013e318279bc51
    Database MEDical Literature Analysis and Retrieval System OnLINE

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