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  1. Article ; Online: An atypical cause of dyspnea.

    Kaeuffer, Charlotte / Ledoux, Marie-Pierre / Herbrecht, Raoul

    European journal of internal medicine

    2019  Volume 68, Page(s) e5–e6

    MeSH term(s) Abdominal Pain/etiology ; Cough/etiology ; Dyspnea/etiology ; Female ; Humans ; Low Back Pain/etiology ; Lung/diagnostic imaging ; Lung/pathology ; Middle Aged ; Pulmonary Alveolar Proteinosis/complications ; Pulmonary Alveolar Proteinosis/diagnosis ; Pulmonary Alveolar Proteinosis/diagnostic imaging ; Pulmonary Alveolar Proteinosis/pathology ; Tomography, X-Ray Computed ; Weight Loss
    Language English
    Publishing date 2019-06-05
    Publishing country Netherlands
    Document type Case Reports ; Journal Article
    ZDB-ID 1038679-8
    ISSN 1879-0828 ; 0953-6205
    ISSN (online) 1879-0828
    ISSN 0953-6205
    DOI 10.1016/j.ejim.2019.05.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2608: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  2. Article ; Online: Characteristics and Treatment of Gordonia spp. Bacteremia, France.

    Barthel, Alia / Ursenbach, Axel / Kaeuffer, Charlotte / Koebel, Christelle / Gravet, Alain / De Briel, Dominique / Dubois, Jacqueline / Haerrel, Elina / Rougier, Estelle / Gerber, Victor

    Emerging infectious diseases

    2023  Volume 29, Issue 5, Page(s) 1025–1028

    Abstract: Systemic Gordonia spp. infections are rare and occur mostly among immunocompromised patients. We analyzed 10 cases of Gordonia bacteremia diagnosed in 3 tertiary care centers in France to assess risk factors, treatment, and clinical outcomes. Most ... ...

    Abstract Systemic Gordonia spp. infections are rare and occur mostly among immunocompromised patients. We analyzed 10 cases of Gordonia bacteremia diagnosed in 3 tertiary care centers in France to assess risk factors, treatment, and clinical outcomes. Most patients were cured within 10 days by using β-lactam antimicrobial therapy and removing central catheters.
    MeSH term(s) Humans ; Risk Factors ; Bacteremia/diagnosis ; Bacteremia/drug therapy ; Bacteremia/epidemiology ; Gordonia Bacterium ; France/epidemiology ; Immunocompromised Host
    Language English
    Publishing date 2023-04-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1380686-5
    ISSN 1080-6059 ; 1080-6040
    ISSN (online) 1080-6059
    ISSN 1080-6040
    DOI 10.3201/eid2905.221901
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4778: Show issues Location:
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  3. Article ; Online: Rapid Radiological Worsening and Cytokine Storm Syndrome in COVID-19 Pneumonia.

    Ruch, Yvon / Kaeuffer, Charlotte / Guffroy, Aurélien / Lefebvre, Nicolas / Hansmann, Yves / Danion, François

    European journal of case reports in internal medicine

    2020  Volume 7, Issue 7, Page(s) 1822

    Abstract: Background: In June 2020, a large randomised controlled clinical trial in the UK found that dexamethasone was effective in reducing the number of deaths in patients with severe coronavirus disease 2019 (COVID-19).: Case description: We describe a ... ...

    Abstract Background: In June 2020, a large randomised controlled clinical trial in the UK found that dexamethasone was effective in reducing the number of deaths in patients with severe coronavirus disease 2019 (COVID-19).
    Case description: We describe a patient with rapid worsening of COVID-19 pneumonia and its dramatic improvement under corticosteroids.
    Discussion: Corticosteroids could be useful in patients with an inflammatory profile, considering that acute respiratory distress syndrome may be the consequence of cytokine storm syndrome.
    Learning points: One of the main pathophysiological hypotheses for severe COVID-19 pneumonia is inappropriate immunological hyperactivation.Corticosteroid therapy may be useful in these patients.
    Keywords covid19
    Language English
    Publishing date 2020-07-02
    Publishing country Italy
    Document type Journal Article
    ISSN 2284-2594
    ISSN (online) 2284-2594
    DOI 10.12890/2020_001822
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  4. Article: First Case of Bacteraemia Due to Carbapenem-Resistant

    Kaeuffer, Charlotte / Ruge, Tiffany / Diancourt, Laure / Romain, Benoît / Ruch, Yvon / Jaulhac, Benoît / Boyer, Pierre H

    Antibiotics (Basel, Switzerland)

    2021  Volume 10, Issue 3

    Abstract: Multidrug resistant (MDR) bacteria are increasingly observed in nosocomial and community-acquired settings. Anaerobes are no exception to this rule, but there are fewer reports of MDR in the scientific literature on anaerobes than there are for other ... ...

    Abstract Multidrug resistant (MDR) bacteria are increasingly observed in nosocomial and community-acquired settings. Anaerobes are no exception to this rule, but there are fewer reports of MDR in the scientific literature on anaerobes than there are for other bacteria. In this short case report, we describe the first case of bacteraemia caused by a multidrug-resistant
    Language English
    Publishing date 2021-03-19
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics10030319
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  5. Article ; Online: Cefepime vs carbapenems for treating third-generation cephalosporin-resistant AmpC β-lactamase-hyperproducing Enterobacterales bloodstream infections: a multicenter retrospective study.

    Hoellinger, Baptiste / Kaeuffer, Charlotte / Boyer, Pierre / Lefebvre, Nicolas / Hansmann, Yves / Robert, Amandine / Severac, François / Gravet, Alain / Danion, François / Ruch, Yvon / Ursenbach, Axel

    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

    2023  Volume 134, Page(s) 273–279

    Abstract: Objectives: AmpC β-lactamase-hyperproducing Enterobacterales (ABLHE) bloodstream infections (BSI) are emerging and leading to therapeutic challenges worldwide. Prescriptions of carbapenems may lead to the emergence of resistance. This study aimed to ... ...

    Abstract Objectives: AmpC β-lactamase-hyperproducing Enterobacterales (ABLHE) bloodstream infections (BSI) are emerging and leading to therapeutic challenges worldwide. Prescriptions of carbapenems may lead to the emergence of resistance. This study aimed to compare cefepime with carbapenems for the treatment of third-generation cephalosporin-resistant ABLHE BSI.
    Methods: This retrospective multicenter study included patients with ABLHE BSI from two tertiary hospitals in France, between July 2017 and July 2022. Non-AmpC-producing Enterobacterales, extended-spectrum β-lactamase, and carbapenemase-producing Enterobacterales were excluded. Cefepime was prescribed only in case of minimal inhibitory concentration ≤1 mg/l. The primary outcome was 30-day in-hospital mortality from the date of index blood culture. Secondary outcomes were infection recurrence and treatment toxicity. An inverse probability of treatment weighting approach was used to balance the baseline characteristics between the two groups.
    Results: We analyzed 164 BSI, which included 77 in the cefepime group and 87 in the carbapenem group. In the weighted cohort, the 30-day mortality rates were similar between the cefepime group (23.3%) and the carbapenem group (19.6%) with a relative risk of 1.19 (95% confidence interval, 0.61-2.33 P = 0.614). No significant difference in recurrence or toxicity was found between the two groups.
    Conclusion: This study adds evidence in favor of the use of cefepime for treating third-generation cephalosporin-resistant ABLHE BSI in case of minimal inhibitory concentration ≤ 1 mg/l, which could spare carbapenems.
    MeSH term(s) Humans ; Cefepime/therapeutic use ; Carbapenems/pharmacology ; Carbapenems/therapeutic use ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Retrospective Studies ; Enterobacteriaceae ; Enterobacteriaceae Infections/drug therapy ; beta-Lactamases ; Sepsis/drug therapy ; Gammaproteobacteria ; Microbial Sensitivity Tests
    Chemical Substances Cefepime (807PW4VQE3) ; Carbapenems ; AmpC beta-lactamases (EC 3.5.2.6) ; Anti-Bacterial Agents ; beta-Lactamases (EC 3.5.2.6)
    Language English
    Publishing date 2023-07-14
    Publishing country Canada
    Document type Multicenter Study ; Journal Article
    ZDB-ID 1331197-9
    ISSN 1878-3511 ; 1201-9712
    ISSN (online) 1878-3511
    ISSN 1201-9712
    DOI 10.1016/j.ijid.2023.07.004
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    Zs.A 4516: Show issues Location:
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  6. Article ; Online: Characteristics and Treatment of Gordonia spp. Bacteremia, France

    Alia Barthel / Axel Ursenbach / Charlotte Kaeuffer / Christelle Koebel / Alain Gravet / Dominique De Briel / Jacqueline Dubois / Elina Haerrel / Estelle Rougier / Victor Gerber

    Emerging Infectious Diseases, Vol 29, Iss 5, Pp 1025-

    2023  Volume 1028

    Abstract: Systemic Gordonia spp. infections are rare and occur mostly among immunocompromised patients. We analyzed 10 cases of Gordonia bacteremia diagnosed in 3 tertiary care centers in France to assess risk factors, treatment, and clinical outcomes. Most ... ...

    Abstract Systemic Gordonia spp. infections are rare and occur mostly among immunocompromised patients. We analyzed 10 cases of Gordonia bacteremia diagnosed in 3 tertiary care centers in France to assess risk factors, treatment, and clinical outcomes. Most patients were cured within 10 days by using β-lactam antimicrobial therapy and removing central catheters.
    Keywords Gordonia ; bacteremia ; bacteria ; Gram-positive ; nosocomial infections ; antimicrobial resistance ; Medicine ; R ; Infectious and parasitic diseases ; RC109-216
    Language English
    Publishing date 2023-05-01T00:00:00Z
    Publisher Centers for Disease Control and Prevention
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Rapid Radiological Worsening and Cytokine Storm Syndrome in COVID-19 Pneumonia

    Yvon Ruch / Charlotte Kaeuffer / Aurélien Guffroy / Nicolas Lefebvre / Yves Hansmann / François Danion

    European Journal of Case Reports in Internal Medicine (2020)

    2020  

    Abstract: Background: In June 2020, a large randomised controlled clinical trial in the UK found that dexamethasone was effective in reducing the number of deaths in patients with severe coronavirus disease 2019 (COVID-19). Case description: We describe a patient ... ...

    Abstract Background: In June 2020, a large randomised controlled clinical trial in the UK found that dexamethasone was effective in reducing the number of deaths in patients with severe coronavirus disease 2019 (COVID-19). Case description: We describe a patient with rapid worsening of COVID-19 pneumonia and its dramatic improvement under corticosteroids. Discussion: Corticosteroids could be useful in patients with an inflammatory profile, considering that acute respiratory distress syndrome may be the consequence of cytokine storm syndrome.
    Keywords covid-19 ; coronavirus ; cytokine storm syndrome ; computed tomography ; corticosteroids ; Medicine ; R ; covid19
    Language English
    Publishing date 2020-07-01T00:00:00Z
    Publisher SMC MEDIA SRL
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: The Good, the Bad, and the Hoax: When Publication Instantaneously Impacts Treatment Strategies for COVID-19.

    Danion, François / Ruch, Yvon / Fourtage, Marion / Kaeuffer, Charlotte / Greigert, Valentin / Lefebvre, Nicolas / Muller, Joris / Nai, Thierry / Hansmann, Yves

    Antimicrobial agents and chemotherapy

    2020  Volume 64, Issue 8

    MeSH term(s) Antiviral Agents/therapeutic use ; Azithromycin/therapeutic use ; Betacoronavirus/drug effects ; Coronavirus Infections/drug therapy ; Deception ; Drug Combinations ; France ; Humans ; Hydroxychloroquine/therapeutic use ; Lopinavir/therapeutic use ; Pandemics ; Pneumonia, Viral/drug therapy ; Ritonavir/therapeutic use ; Scholarly Communication
    Chemical Substances Antiviral Agents ; Drug Combinations ; lopinavir-ritonavir drug combination ; Lopinavir (2494G1JF75) ; Hydroxychloroquine (4QWG6N8QKH) ; Azithromycin (83905-01-5) ; Ritonavir (O3J8G9O825)
    Keywords covid19
    Language English
    Publishing date 2020-07-22
    Publishing country United States
    Document type Letter
    ZDB-ID 217602-6
    ISSN 1098-6596 ; 0066-4804
    ISSN (online) 1098-6596
    ISSN 0066-4804
    DOI 10.1128/AAC.01127-20
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 809: Show issues Location:
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    Einzelsignatur: Show issues

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  9. Article ; Online: Protracted SARS-CoV-2 pneumonia with rituximab treatment: About two cases.

    Gerber, Victor / Velay, Aurélie / Boehn, Louis / Solis, Morgane / Kaeuffer, Charlotte / Rougier, Estelle / Ursenbach, Axel / Hansmann, Yves / Lefebvre, Nicolas / Danion, François / Ruch, Yvon

    Journal of medical virology

    2021  Volume 93, Issue 7, Page(s) 4141–4144

    MeSH term(s) Aged ; Antigens, CD20/drug effects ; Autoimmune Diseases/drug therapy ; COVID-19/pathology ; Humans ; Immunologic Factors/adverse effects ; Immunologic Factors/therapeutic use ; Male ; Middle Aged ; Rituximab/adverse effects ; Rituximab/therapeutic use ; SARS-CoV-2/immunology ; Viral Load/drug effects
    Chemical Substances Antigens, CD20 ; Immunologic Factors ; Rituximab (4F4X42SYQ6)
    Language English
    Publishing date 2021-03-14
    Publishing country United States
    Document type Case Reports ; Letter
    ZDB-ID 752392-0
    ISSN 1096-9071 ; 0146-6615
    ISSN (online) 1096-9071
    ISSN 0146-6615
    DOI 10.1002/jmv.26921
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  10. Article: The Good, the Bad, and the Hoax: When Publication Instantaneously Impacts Treatment Strategies for COVID-19

    Danion, François / Ruch, Yvon / Fourtage, Marion / Kaeuffer, Charlotte / Greigert, Valentin / Lefebvre, Nicolas / Muller, Joris / Nai, Thierry / Hansmann, Yves
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #591663
    Database COVID19

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