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  1. Article ; Online: A G polymorphism in the CRBN gene acts as a biomarker of response to treatment with lenalidomide in low/int-1 risk MDS without del(5q).

    Sardnal, V / Rouquette, A / Kaltenbach, S / Bally, C / Chesnais, V / Leschi, C / Ades, L / Santini, V / Park, S / Toma, A / Fenaux, P / Dreyfus, F / Fontenay, M / Kosmider, O

    Leukemia

    2013  Volume 27, Issue 7, Page(s) 1610–1613

    MeSH term(s) Aged ; Aged, 80 and over ; Angiogenesis Inhibitors/therapeutic use ; Biomarkers, Tumor/genetics ; Chromosome Deletion ; Humans ; Lenalidomide ; Middle Aged ; Myelodysplastic Syndromes/drug therapy ; Myelodysplastic Syndromes/genetics ; Peptide Hydrolases/genetics ; Polymorphism, Genetic/genetics ; Risk ; Thalidomide/analogs & derivatives ; Thalidomide/therapeutic use
    Chemical Substances Angiogenesis Inhibitors ; Biomarkers, Tumor ; CRBN protein, human ; Thalidomide (4Z8R6ORS6L) ; Peptide Hydrolases (EC 3.4.-) ; Lenalidomide (F0P408N6V4)
    Language English
    Publishing date 2013-02-26
    Publishing country England
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 807030-1
    ISSN 1476-5551 ; 0887-6924
    ISSN (online) 1476-5551
    ISSN 0887-6924
    DOI 10.1038/leu.2013.59
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  2. Article: Predictive factors of response and survival in myelodysplastic syndrome treated with erythropoietin and G-CSF: the GFM experience.

    Park, Sophie / Grabar, Sophie / Kelaidi, Charikleia / Beyne-Rauzy, Odile / Picard, Françoise / Bardet, Valérie / Coiteux, Valérie / Leroux, Geneviève / Lepelley, Pascale / Daniel, Marie-Thérèse / Cheze, Stéphane / Mahé, Béatrice / Ferrant, Augustin / Ravoet, Christophe / Escoffre-Barbe, Martine / Adès, Lionel / Vey, Norbert / Aljassem, Lina / Stamatoullas, Aspasia /
    Mannone, Lionel / Dombret, Hervé / Bourgeois, Keith / Greenberg, Peter / Fenaux, Pierre / Dreyfus, François

    Blood

    2007  Volume 111, Issue 2, Page(s) 574–582

    Abstract: We analyzed prognostic factors of response, response duration, and possible impact on survival of epoetin alpha, epoetin beta, or darbepoetin alpha (DAR) with or without granulocyte colony-stimulating factor in 403 myelodysplastic syndrome (MDS) patients. ...

    Abstract We analyzed prognostic factors of response, response duration, and possible impact on survival of epoetin alpha, epoetin beta, or darbepoetin alpha (DAR) with or without granulocyte colony-stimulating factor in 403 myelodysplastic syndrome (MDS) patients. Sixty-two percent (40% major and 22% minor) and 50% erythroid responses were seen, and median response duration was 20 and 24 months according to IWG 2000 and 2006 criteria, respectively. Significantly higher response rates were observed with less than 10% blasts, low and int-1 International Prognostic Scoring System (IPSS), red blood cell transfusion independence, serum EPO level less than 200 IU/L, and, with IWG 2006 criteria only, shorter interval between diagnosis and treatment. Significantly longer response duration was associated with major response (IWG 2000 criteria), IPSS low to INT-1, blasts less than 5%, and absence of multilineage dysplasia. Minor responses according to IWG 2000 were reclassified as "nonresponders" or "responders" according to IWG 2006 criteria. However, among those IWG 2000 minor responders, response duration did not differ between IWG 2006 responders and nonresponders. Multivariate adjusted comparisons of survival between our cohort and the untreated MDS cohort used to design IPSS showed similar rate of progression to acute myeloid leukemia in both cohorts, but significantly better overall survival in our cohort, suggesting that epoetin or DAR treatment may have a favorable survival impact in MDS.
    MeSH term(s) Aged ; Blast Crisis/diagnosis ; Blast Crisis/drug therapy ; Blast Crisis/mortality ; Cohort Studies ; Disease-Free Survival ; Erythrocyte Transfusion ; Erythropoietin/administration & dosage ; Erythropoietin/pharmacokinetics ; Female ; Granulocyte Colony-Stimulating Factor/administration & dosage ; Granulocyte Colony-Stimulating Factor/pharmacokinetics ; Humans ; Male ; Myelodysplastic Syndromes/diagnosis ; Myelodysplastic Syndromes/mortality ; Myelodysplastic Syndromes/therapy ; Predictive Value of Tests ; Survival Rate ; Time Factors
    Chemical Substances Erythropoietin (11096-26-7) ; Granulocyte Colony-Stimulating Factor (143011-72-7)
    Language English
    Publishing date 2007-10-16
    Publishing country United States
    Document type Clinical Trial ; Comparative Study ; Journal Article ; Multicenter Study
    ZDB-ID 80069-7
    ISSN 1528-0020 ; 0006-4971
    ISSN (online) 1528-0020
    ISSN 0006-4971
    DOI 10.1182/blood-2007-06-096370
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  3. Article: Initiation à l'électroencéphalographie: E.E.G. d'un cas de maladie d'Addison.

    BRICAIRE, H / MISES, R / DREYFUS-BRISAC, C / FISCHGOLD, H

    La Presse medicale

    2003  Volume 61, Issue 36, Page(s) 750–751

    Title translation Introduction to electroencephalography: EEG of a patient with Addison's disease.
    MeSH term(s) Addison Disease/physiology ; Adrenal Insufficiency ; Electroencephalography ; Humans ; Hypoadrenocorticism, Familial
    Language Undetermined
    Publishing date 2003-01-17
    Publishing country France
    Document type Journal Article
    ZDB-ID 120943-7
    ISSN 2213-0276 ; 0032-7867 ; 0755-4982 ; 0301-1518
    ISSN (online) 2213-0276
    ISSN 0032-7867 ; 0755-4982 ; 0301-1518
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  4. Article: Maladie de Paget compliquée d'un lymphome Ki-1 avec sécrétion de facteur de croissance G-CSF.

    Irani, L / Hilliquin, P / Dreyfus, F / Renoux, M / Louvel, G / Menkès, C J

    Revue du rhumatisme (Ed. francaise : 1993)

    1994  Volume 61, Issue 9, Page(s) 641–644

    Abstract: Development of lysis within an area of pagetic bone suggests a sarcoma. We report the case of a 61-year-old woman who had increasingly severe pain in her right hip and a decline in general health. The roentgenogram of the pelvis showed previously known ... ...

    Title translation Paget disease, complicated by Ki-1 lymphoma with G-CSF growth factor secretion.
    Abstract Development of lysis within an area of pagetic bone suggests a sarcoma. We report the case of a 61-year-old woman who had increasingly severe pain in her right hip and a decline in general health. The roentgenogram of the pelvis showed previously known pagetic lesions of the right half of the pelvis and osteolysis of the roof of the acetabulum. Additional imaging studies (ultrasonography, computed tomography, and magnetic resonance imaging) disclosed a pelvic tumor extending on either side of the right ilium. The peripheral white blood cell count was markedly elevated (93,000/mm3) as a result of inappropriate secretion of granulocyte-colony-stimulating factor. The tumor was an anaplastic large cell lymphoma of T-cell origin with CD30 positivity, i.e., a Ki-1 lymphoma. Most CD30-positive lymphomas are high-grade tumors. There has been only one previous report of Ki-1 lymphoma with production of granulocyte-colony-stimulating factor and hyperleukocytosis. It has been suggested that cytokines may influence tumor growth. Unusual features in our case include development of the Ki-1 lymphoma in an area of pagetic bone and presence of a leukemic syndrome due to increased production of a growth factor.
    MeSH term(s) Bone Neoplasms/etiology ; Female ; Granulocyte Colony-Stimulating Factor/secretion ; Humans ; Ilium ; Lymphoma, Large-Cell, Anaplastic/etiology ; Middle Aged ; Osteitis Deformans/complications ; Osteolysis/etiology
    Chemical Substances Granulocyte Colony-Stimulating Factor (143011-72-7)
    Language French
    Publishing date 1994-10
    Publishing country France
    Document type Case Reports ; Journal Article
    ZDB-ID 2036640-1
    ISSN 1768-3130 ; 1169-8330
    ISSN (online) 1768-3130
    ISSN 1169-8330
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  5. Article ; Online: "In these pandemic times": The role of temporal meanings in ambient affiliation about COVID-19 on Twitter.

    Zappavigna, Michele / Dreyfus, Shoshana

    Discourse, context & media

    2022  Volume 47, Page(s) 100595

    Abstract: ... to the shared experience of being in a pandemic (e.g., ...

    Abstract This paper explores the role of a particular set of commonly occurring temporal meanings relating to the shared experience of being in a pandemic (e.g.,
    Language English
    Publishing date 2022-04-27
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2211-6966
    ISSN (online) 2211-6966
    DOI 10.1016/j.dcm.2022.100595
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  6. Article ; Online: Scoping review on communication systems used by adults with severe/profound intellectual disability for functional communication.

    Danker, Joanne / Dreyfus, Shoshana / Strnadová, Iva / Pilkinton, Mary

    Journal of applied research in intellectual disabilities : JARID

    2023  Volume 36, Issue 5, Page(s) 951–965

    Abstract: ... Several barriers (e.g., individual factors related to adults with severe/profound intellectual disability, others' ... attitudes, behaviour and knowledge) to and enablers (e.g., accessibility and availability ...

    Abstract Background: Adults with severe/profound intellectual disability typically face poor communication outcomes as they are often nonverbal and need their supporters to provide for their communication needs. This review aimed to identify studies focused on the communication resources people with severe/profound intellectual disability use for functional communication, and the enablers and barriers to functional communication.
    Methods: Nine databases were systematically reviewed with keywords pertaining to the functional communication of adults with severe/profound intellectual disability. Out of 3427 identified articles, 12 met the inclusion criteria. Hand searches and ancestral searches identified another 4 articles. Out of the 16 articles, two did not meet the quality assessment criteria and were excluded. Thus, 14 articles were included in this review.
    Results: The findings revealed that picture exchange communication systems is the most common communication system used to support the development of functional communication. The most common functions enabled by the communication systems were choice-making and making requests. Several barriers (e.g., individual factors related to adults with severe/profound intellectual disability, others' attitudes, behaviour and knowledge) to and enablers (e.g., accessibility and availability of the communication system, training for those supporting adults with severe/profound intellectual disability) of functional communication were identified.
    Conclusions: Removing the barriers and enabling functional communication is essential to developing the functional communication of adults with severe/profound intellectual disability.
    MeSH term(s) Humans ; Adult ; Intellectual Disability ; Communication
    Language English
    Publishing date 2023-06-21
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1326222-1
    ISSN 1468-3148 ; 0952-9608 ; 1360-2322
    ISSN (online) 1468-3148
    ISSN 0952-9608 ; 1360-2322
    DOI 10.1111/jar.13133
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    Zs.A 4157: Show issues Location:
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  7. Article ; Online: Tricuspid Transcatheter Edge-to-Edge Valve Repair: Sooner Rather Than Later.

    Messika-Zeitoun, David / Burwash, Ian G / Dreyfus, Julien

    JACC. Cardiovascular interventions

    2022  Volume 15, Issue 2, Page(s) 190–192

    MeSH term(s) Cardiac Surgical Procedures ; Humans ; Treatment Outcome ; Tricuspid Valve Insufficiency/diagnostic imaging ; Tricuspid Valve Insufficiency/surgery
    Language English
    Publishing date 2022-01-17
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2452157-7
    ISSN 1876-7605 ; 1936-8798
    ISSN (online) 1876-7605
    ISSN 1936-8798
    DOI 10.1016/j.jcin.2021.11.014
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  8. Article: [The place of saluretics in the treatment of obesity, especially that of G-33182].

    GILBERT-DREYFUS / SEBAOUN, J / DELZANT, G

    La Presse medicale

    1961  Volume 69, Page(s) 679–680

    MeSH term(s) Diuretics/therapy ; Obesity/therapy
    Chemical Substances Diuretics
    Language French
    Publishing date 1961-03-25
    Publishing country France
    Document type Journal Article
    ZDB-ID 120943-7
    ISSN 2213-0276 ; 0032-7867 ; 0755-4982 ; 0301-1518
    ISSN (online) 2213-0276
    ISSN 0032-7867 ; 0755-4982 ; 0301-1518
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  9. Article ; Online: How to shape the future of cardiology and cardiac surgery?

    Dreyfus, Gilles / Windecker, Stephan

    European heart journal

    2020  Volume 41, Issue 38, Page(s) 3693–3701

    MeSH term(s) Cardiac Surgical Procedures ; Cardiology ; Humans ; Thoracic Surgery
    Language English
    Publishing date 2020-10-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 603098-1
    ISSN 1522-9645 ; 0195-668X
    ISSN (online) 1522-9645
    ISSN 0195-668X
    DOI 10.1093/eurheartj/ehaa707
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    Zs.MO 640: Show issues

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  10. Article ; Online: Living in a Foster Home: The Single Subpolar Flagellum Fla1 of

    Camarena, Laura / Dreyfus, Georges

    Biomolecules

    2020  Volume 10, Issue 5

    Abstract: Rhodobacter ... ...

    Abstract Rhodobacter sphaeroides
    MeSH term(s) Bacterial Proteins/chemistry ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Flagella/chemistry ; Flagella/genetics ; Flagella/metabolism ; Membrane Proteins/chemistry ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; Rhodobacter sphaeroides/genetics ; Rhodobacter sphaeroides/metabolism
    Chemical Substances Bacterial Proteins ; Membrane Proteins ; FliL protein, Bacteria (147258-60-4)
    Language English
    Publishing date 2020-05-16
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2701262-1
    ISSN 2218-273X ; 2218-273X
    ISSN (online) 2218-273X
    ISSN 2218-273X
    DOI 10.3390/biom10050774
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