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  1. Article ; Online: K.P. DINESH, S.P. VIJAYAKUMAR, B.H. CHANNAKESHAVAMURTHY, VARUN R. TORSEKAR, NIRMAL U. KULKARNI & KARTIK SHANKER (2015) SYSTEMATIC STATUS OF FEJERVARYA (AMPHIBIA, ANURA, DICROGLOSSIDAE) FROM SOUTH AND SE ASIA WITH THE DESCRIPTION OF A NEW SPECIES FROM THE WESTERN GHATS OF PENINSULAR INDIA. Zootaxa, 3999(1): 079-094.

    Dinesh, K P / Vijayakumar, S P / Channakeshavamurthy, B H / Torsekar, Varun R / Kulkarni, Nirmal U / Shanker, Kartik

    Zootaxa

    2015  Volume 4033, Issue 4, Page(s) 600

    Language English
    Publishing date 2015-10-27
    Publishing country New Zealand
    Document type Published Erratum
    ISSN 1175-5334
    ISSN (online) 1175-5334
    DOI 10.11646/zootaxa.4033.4.10
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Conference proceedings: Successful endoscopic management of a juxta-pyloric lumen obstructing Lipoma using Endoscopic submucosal dissection (ESD)

    Gandhi, A. / Jain, H. / Kahalekar, V. / Takalkar, U. / Takle, B. / Kulkarni, U. / Apsingekar, P. / Tekale, J. / Daunde, V. / Bapaye, A.

    Endoscopy

    2024  Volume 56, Issue S 02

    Event/congress ESGE Days 2024, Berlin, Germany, 2024-04-25
    Language English
    Publishing date 2024-04-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/s-0044-1782921
    Database Thieme publisher's database

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  3. Article: The Rationale for Discarding Blood and Its Components in a Tertiary Care Hospital Blood Bank in North Karnataka.

    Kulkarni, Keshav R / Kulkarni, Pavan / Jamkhandi, Uma

    Cureus

    2022  Volume 14, Issue 11, Page(s) e31112

    Abstract: Background Human blood is an essential human element for which no substitute has yet been discovered. This study aims to determine the causes of discarding blood and its components. Material and methods A retrospective study of three years (January 1, ... ...

    Abstract Background Human blood is an essential human element for which no substitute has yet been discovered. This study aims to determine the causes of discarding blood and its components. Material and methods A retrospective study of three years (January 1, 2018, to December 31, 2020) was performed in a tertiary care hospital blood bank. Data were retrieved from the various registers and analysed. Results During this study, a total of 3280 units, 1868 units, and 486 units of whole blood were collected in 2018, 2019, and 2020, respectively. It was observed that the discard rate of whole blood was 9.48%, 17.23%, and 43% in 2018, 2019, and 2020, respectively. The discard rate for components varied, such as for packed red blood cells (PRBC), it was 1.76% in 2018, 1.73% in 2019, and 3.03% in 2020, for fresh frozen plasma (FFP), it was 4.08% in 2018, 4.36% in 2019, and 2.20% in 2020, and for platelets, it was 43.08% in 2018, 31.56% in 2019, and 45.03% in 2020. A total of 311, 322, and 209 units of whole blood were discarded in 2018, 2019, and 2020, respectively. The total whole blood and blood components were discarded for various reasons such as undiagnosed sterility (HIV, hepatitis B surface antigen, hepatitis C virus, Venereal Disease Research Laboratory), quality control, underweight, hemolysis unit, expiry, and polycythemia. Conclusion The wastage of stored blood and its components is inevitable. Still, it can be minimised by optimum utilisation and implementation of blood transfusion services (BTS) along with the education and training of blood bank staff. There are various reasons for the wastage of blood and its components, such as unscreened transfusion-transmitted diseases, sterility, storage, less bleeding, expiry, hemolysis samples and polycythemia. Self-regular audits, coordination between hospital and blood bank staff, proper storage and handling of blood units, strict donor selection and deferral criteria, along with appropriate history taking, will help minimise the wastage of blood or its components.
    Language English
    Publishing date 2022-11-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.31112
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Response of pink bollworm Pectinophora gossypiella (Saunders) to Cry1Ac and Cry2Ab toxin

    P. Likhitha / D. B. Undirwade / U. S. Kulkarni / A. V. Kolhe / M. P. Moharil

    Egyptian Journal of Biological Pest Control, Vol 33, Iss 1, Pp 1-

    2023  Volume 9

    Abstract: ... to determine the reaction of Pectinophora gossypiella to Cry1Ac and Cry2Ab toxins. Results Neonates of P ... Neonates of P. gossypiella collected from six different locations in Vidarbha were exposed to seven ...

    Abstract Abstract Background During field surveillance in Gujarat, India, in 2009, scientists found that pink bollworm was surviving in the first generation of Bollgard cotton, which contains a single protein. This survival was observed in four districts of Gujarat. From 2012 to 2014, surveys revealed that pink bollworm larvae had higher survival rates on Bollgard II cotton in Amreli and Bhavnagar districts. In 2016, a pink bollworm outbreak in Maharashtra caused significant losses in cotton production, leading to damage, yield losses, and increased management costs in several regions. The objective of the present study was to determine the reaction of Pectinophora gossypiella to Cry1Ac and Cry2Ab toxins. Results Neonates of P. gossypiella collected from six distinct locations in Vidarbha were subjected to seven different concentrations of Cry1Ac. The highest LC50 value was recorded in the population collection of Yavatmal (1.362 μg/ml diet) but the lowest LC50 value of 0.600 μg/ml diet in Buldana population. The highest MIC50 value was recorded in the population collected from Yavatmal (0.743 μg/ml diet) and the lowest MIC50 value of 0.413 μg/ml diet in the Buldana population (0.431 μg/ml diet). The highest IC50 value was recorded in the population collected from Yavatmal (0.303 μg/ml diet) but the lowest IC50 value of 0.127 μg/ml diet in the Buldana population. Neonates of P. gossypiella collected from six different locations in Vidarbha were exposed to seven different concentrations (9.0, 3.0, 1.0, 0.333, 0.111, 0.037 and 0.012 for Cry1Ac and 27.0, 9.0, 3.0, 1.0, 0.333, 0.111 and 0.037 μg/ml for Cry2Ab) which revealed that the Yavatmal population had the highest LC50 value of 94.294 μg/ml diet and the lowest LC50 value was recorded in the Amravati population (42.144 μg/ml diet). The highest MIC50 value of 27.258 μg/ml diet was recorded in Buldana population, but the lowest MIC50 value was recorded in the Amravati population (12.881 μg/ml diet). The highest IC50 value of 3.209 μg/ml diet was observed in Yavatmal ...
    Keywords Cry1Ac ; Cry2Ab ; Bioassay ; Pectinophora gossypiella ; LC50 ; MIC50 ; Agriculture ; S
    Subject code 590
    Language English
    Publishing date 2023-06-01T00:00:00Z
    Publisher SpringerOpen
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Cry toxin expression in different plant parts of Bt cotton at different phenological stages

    P. Likhitha / D. B. Undirwade / U. S. Kulkarni / A. V. Kolhe / M. P. Moharil

    Egyptian Journal of Biological Pest Control, Vol 33, Iss 1, Pp 1-

    2023  Volume 7

    Abstract: Abstract Background Compared to Bollgard-I, the utilization of Cry2Ab protein in Bollgard-II cotton cultivars enhances insect control. Field and laboratory studies demonstrated reduction in the numbers of bollworm-infested terminals, squares, and bolls ... ...

    Abstract Abstract Background Compared to Bollgard-I, the utilization of Cry2Ab protein in Bollgard-II cotton cultivars enhances insect control. Field and laboratory studies demonstrated reduction in the numbers of bollworm-infested terminals, squares, and bolls in Bollgard-II cotton lines when compared to both Bollgard-I and non-Bollgard cotton cultivars. This indicates that the combination of Cry2Ab with Cry1Ac increased the overall expression of proteins. The expression of Cry protein varied across different plant parts, such as leaves, bracts, squares, and bolls. As the season progresses, the expression of Cry protein decreased in these plant parts. Leaves exhibited the highest levels of Cry protein expression, followed by squares, flowers, and bolls. Variation in the expression levels of delta endotoxins in different plant parts was one of the contributing factors to the survival of pest populations on Bt cotton. Results Using a commercially available QL 96 ELISA plate kit, the concentration of delta endotoxin in various plant parts at different phenological stages was determined in twelve BG-II cotton hybrids, namely Ajeet-155, JKCH-2245, RCH-3863, NCS-866, MRC-7373, JKCH-99, MRC-7387, NCEH-21, ANKR-3324, NCSI-1904, and NCHB 9902. Cry1Ac and Cry2Ab protein levels were determined from samples of flowers and fruiting parts (Rind, locule, seed, locule wall and seed) at 40, 75, 100 and 125 days after sowing (DAS) over two consecutive years 2018–2019 and 2019–2020. Cry1Ac protein content and expression was the highest at 100DAS in locule, seed and rind; followed by rind and locule wall and seed in green bolls at 125 DAS; followed by seed, locule, rind and flowers at 75 DAS; followed by flowers at 40 DAS in all the tested twelve Bollgard-II hybrids. Cry2Ab protein content and expression was the highest at 125DAS in locule wall and seed and rind, followed by seed, locule and rind in green bolls at 100 DAS, followed by seed, locule, rind and flowers at 75 DAS, then by flowers at 40 DAS in all the tested twelve Bollgard-II ...
    Keywords Cry1Ac ; Cry2Ab ; Toxin expression ; ELISA ; Bt cotton hybrids ; Phenological stages ; Agriculture ; S
    Subject code 580
    Language English
    Publishing date 2023-09-01T00:00:00Z
    Publisher SpringerOpen
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Book ; Online: SegViz

    Kanhere, Adway U. / Kulkarni, Pranav / Yi, Paul H. / Parekh, Vishwa S.

    A federated-learning based framework for multi-organ segmentation on heterogeneous data sets with partial annotations

    2023  

    Abstract: ... pancreas, and kidneys, respectively, significantly ($p<0.05$) better (except spleen) than the dice scores ... significantly ($p<0.05$) performed poorly on the test dataset with dice scores of 0.65, 0, 0.55, and 0.68 ...

    Abstract Segmentation is one of the most primary tasks in deep learning for medical imaging, owing to its multiple downstream clinical applications. However, generating manual annotations for medical images is time-consuming, requires high skill, and is an expensive effort, especially for 3D images. One potential solution is to aggregate knowledge from partially annotated datasets from multiple groups to collaboratively train global models using Federated Learning. To this end, we propose SegViz, a federated learning-based framework to train a segmentation model from distributed non-i.i.d datasets with partial annotations. The performance of SegViz was compared against training individual models separately on each dataset as well as centrally aggregating all the datasets in one place and training a single model. The SegViz framework using FedBN as the aggregation strategy demonstrated excellent performance on the external BTCV set with dice scores of 0.93, 0.83, 0.55, and 0.75 for segmentation of liver, spleen, pancreas, and kidneys, respectively, significantly ($p<0.05$) better (except spleen) than the dice scores of 0.87, 0.83, 0.42, and 0.48 for the baseline models. In contrast, the central aggregation model significantly ($p<0.05$) performed poorly on the test dataset with dice scores of 0.65, 0, 0.55, and 0.68. Our results demonstrate the potential of the SegViz framework to train multi-task models from distributed datasets with partial labels. All our implementations are open-source and available at https://anonymous.4open.science/r/SegViz-B746
    Keywords Computer Science - Computer Vision and Pattern Recognition ; Computer Science - Artificial Intelligence ; Computer Science - Machine Learning
    Subject code 006
    Publishing date 2023-01-17
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Postnatal Steroids Use for Bronchopulmonary Dysplasia in a Quaternary Care NICU.

    Kanagaraj, Uthayakumaran / Tan, Jason / Soraisham, Amuchou / Lodha, Abhay / Shah, Prakesh / Kulkarni, Tapas / Shivananda, Sandesh

    American journal of perinatology

    2024  

    Abstract: Objective:  Intercenter variation and trends in postnatal steroids (PNS) use among preterm infants for prevention or treatment of bronchopulmonary dysplasia (BPD) is known. Understanding intracenter PNS use patterns facilitate implementation of center- ... ...

    Abstract Objective:  Intercenter variation and trends in postnatal steroids (PNS) use among preterm infants for prevention or treatment of bronchopulmonary dysplasia (BPD) is known. Understanding intracenter PNS use patterns facilitate implementation of center-specific change interventions to optimize outcomes.This study aimed to (i) quantify the proportion of infants who received PNS, and describe the timing, type, trends over time, regimen used, and deviations, and (2) describe the clinical characteristics and unadjusted outcomes of infants who received PNS.
    Study design:  This was a cohort study in a quaternary neonatal intensive care unit including infants born at less than 33 weeks, and who received PNS for prevention or treatment of BPD between 2011 and 2021. Following data were included: proportion of babies who received PNS; type of PNS; age at initiation and duration; trends over time; deviation from published regimen; morbidity, mortality, and cointerventions.
    Results:  One hundred and eighty four infants (8% of <33 week' infants) received PNS. The median (interquartile range [IQR]) gestational age and birth weight were 25 (24-26) weeks and 720 (625-841) grams, respectively. The median (IQR) day of initiation and duration of PNS use were 29 (19-38) and 10 (10-22) days, respectively. One hundred and fifty-seven (85%) infants received dexamethasone (DX) and 22 (12%) received hydrocortisone as the first PNS course, and 71 (39%) infants received multiple courses. The proportion of infants receiving PNS remained unchanged, but the cumulative median dose received for BPD per patient increased by 56%. Nearly one-third of cumulative PNS dose came from PNS used for non-BPD indications. Forty-six percent infants had a deviation from published regimen (±20% deviation in duration or ±10% deviation in dose). Survival, survival without major morbidity, moderate-to-severe BPD, and technology dependence at discharge were 87, 2, 91, and 67%, respectively.
    Conclusion:  Increased variation in PNS use, deviation from published regimen, and concurrent PNS exposure from non-BPD indication offer insights into implementing interventions to improve processes.
    Key points: · In this quaternary NICU, 8% of infants born before 33 weeks were administered postnatal steroids (PNS).. · The percentage of infants given PNS remained stable; however, the cumulative dose per patient for BPD rose.. · The study identified targeted interventions to minimize clinical practice variations at the center..
    Language English
    Publishing date 2024-03-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 605671-4
    ISSN 1098-8785 ; 0735-1631
    ISSN (online) 1098-8785
    ISSN 0735-1631
    DOI 10.1055/a-2267-4363
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Re: "Improved Eyelid Muscle Tension Balance with Refined Frontalis Muscle Flap Suspension in the Treatment of Severe Ptosis".

    Saini, Pragya / Tanwar, Meghana / Kulkarni, Pooja / Kim, Usha

    Ophthalmic plastic and reconstructive surgery

    2022  Volume 38, Issue 3, Page(s) 306–307

    MeSH term(s) Blepharoplasty ; Blepharoptosis/surgery ; Eyelids/surgery ; Humans ; Muscle Tonus ; Oculomotor Muscles/surgery
    Language English
    Publishing date 2022-05-11
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 632830-1
    ISSN 1537-2677 ; 0740-9303
    ISSN (online) 1537-2677
    ISSN 0740-9303
    DOI 10.1097/IOP.0000000000002198
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Commentary : Combating COVID-19-associated mucormycosis with limited resources.

    Kim, Usha / Kulkarni, Pooja / Saini, Pragya

    Indian journal of ophthalmology

    2022  Volume 70, Issue 6, Page(s) 2169

    MeSH term(s) COVID-19 ; Humans ; Mucorales ; Mucormycosis/diagnosis ; Mucormycosis/drug therapy
    Language English
    Publishing date 2022-06-14
    Publishing country India
    Document type Journal Article ; Comment
    ZDB-ID 187392-1
    ISSN 1998-3689 ; 0301-4738
    ISSN (online) 1998-3689
    ISSN 0301-4738
    DOI 10.4103/ijo.IJO_1250_22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Searching beyond nevi - A rare case of neurocutaneous ocular syndrome.

    Kulkarni, Pooja / Tanwar, Meghana / Kim, Usha

    Orbit (Amsterdam, Netherlands)

    2022  Volume 42, Issue 5, Page(s) 553–557

    Abstract: Epidermal nevus syndrome is a rare congenital disorder affecting only a few hundred people in the world. It has ophthalmic, dermatological, and neurological manifestations, with varied presentation. Here, we report a case of two-year-old child who ... ...

    Abstract Epidermal nevus syndrome is a rare congenital disorder affecting only a few hundred people in the world. It has ophthalmic, dermatological, and neurological manifestations, with varied presentation. Here, we report a case of two-year-old child who presented with epibulbar mass in left eye, pigmented nevi over left side of the body and alopecia over left side of parieto-temporal scalp. Imaging confirmed epibulbar mass and presence of calcification of choroid on ipsilateral side with presence of arachnoid cyst of brain with underlying pachygyria. Neurological examination was normal and dermatologist confirmed presence of verrucous nevi over skin. Excisional biopsy of epibulbar mass revealed a complex choristoma with presence of lacrimal gland tissue. Underlying ocular findings were near normal with normal posterior segment. It is a rare form of epidermal nevus syndrome with near normal ocular findings in the presence of anterior and posterior choristoma, which has not been reported.
    MeSH term(s) Child, Preschool ; Humans ; Choristoma/diagnosis ; Choristoma/surgery ; Choristoma/pathology ; Nevus ; Nevus, Pigmented/diagnosis ; Nevus, Pigmented/surgery ; Nevus, Pigmented/pathology ; Skin Neoplasms/diagnosis ; Skin Neoplasms/surgery ; Skin Neoplasms/pathology
    Language English
    Publishing date 2022-03-17
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 603157-2
    ISSN 1744-5108 ; 0167-6830
    ISSN (online) 1744-5108
    ISSN 0167-6830
    DOI 10.1080/01676830.2022.2049609
    Database MEDical Literature Analysis and Retrieval System OnLINE

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