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  1. Book ; Online: Electrical Diseases of the Heart

    Gussak, Ihor / Ackerman, Michael J. / Antzelevitch, Charles / Friedman, Paul A. / Shen, Win-Kuang / Wilde, Arthur A. M.

    Genetics, Mechanisms, Treatment, Prevention

    2008  

    Author's details edited by Ihor Gussak, Charles Antzelevitch, Arthur A. M. Wilde, Paul A. Friedman, Michael J. Ackerman, Win-Kuang Shen
    Keywords Cardiology ; Epidemiology ; Internal medicine ; Neurology
    Language English
    Publisher Springer-Verlag London Limited
    Publishing place London
    Document type Book ; Online
    HBZ-ID TT050387266
    ISBN 978-1-8462-8853-1 ; 978-1-8462-8854-8 ; 1-8462-8853-3 ; 1-8462-8854-1
    DOI 10.1007/978-1-84628-854-8
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article: Molecular pathogenesis of catecholaminergic polymorphic ventricular tachycardia: sex matters!

    Gussak, Ihor

    Heart rhythm

    2006  Volume 3, Issue 7, Page(s) 806–807

    MeSH term(s) Catecholamines/metabolism ; DNA/genetics ; Female ; Humans ; Male ; Mutation ; Risk Factors ; Ryanodine Receptor Calcium Release Channel/genetics ; Sex Factors ; Tachycardia, Ventricular/diagnosis ; Tachycardia, Ventricular/genetics ; Tachycardia, Ventricular/metabolism
    Chemical Substances Catecholamines ; Ryanodine Receptor Calcium Release Channel ; DNA (9007-49-2)
    Language English
    Publishing date 2006-07
    Publishing country United States
    Document type Comment ; Comparative Study ; Editorial
    ZDB-ID 2229357-7
    ISSN 1556-3871 ; 1547-5271
    ISSN (online) 1556-3871
    ISSN 1547-5271
    DOI 10.1016/j.hrthm.2006.05.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6278: Show issues Location:
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  3. Article ; Online: Early repolarization syndrome: a decade of progress.

    Gussak, Ihor / Antzelevitch, Charles

    Journal of electrocardiology

    2013  Volume 46, Issue 2, Page(s) 110–113

    MeSH term(s) Arrhythmias, Cardiac/diagnosis ; Arrhythmias, Cardiac/physiopathology ; Electrocardiography/methods ; Heart Conduction System/physiopathology ; Humans ; Syndrome ; Terminology as Topic
    Language English
    Publishing date 2013-03-13
    Publishing country United States
    Document type Editorial
    ZDB-ID 410286-1
    ISSN 1532-8430 ; 0022-0736
    ISSN (online) 1532-8430
    ISSN 0022-0736
    DOI 10.1016/j.jelectrocard.2012.12.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Author's response to letter to the editor from Perez and Froelicher.

    Antzelevitch, Charles / Gussak, Ihor

    Journal of electrocardiology

    2013  Volume 46, Issue 2, Page(s) 116; discussion 117

    MeSH term(s) Arrhythmias, Cardiac/diagnosis ; Arrhythmias, Cardiac/physiopathology ; Electrocardiography/methods ; Heart Conduction System/physiopathology ; Humans ; Terminology as Topic
    Language English
    Publishing date 2013-01-30
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 410286-1
    ISSN 1532-8430 ; 0022-0736
    ISSN (online) 1532-8430
    ISSN 0022-0736
    DOI 10.1016/j.jelectrocard.2012.12.005
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  5. Article: Sudden cardiac death in nephrology: focus on acquired long QT syndrome.

    Gussak, Ihor / Gussak, Hiie M

    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

    2007  Volume 22, Issue 1, Page(s) 12–14

    MeSH term(s) Arrhythmias, Cardiac/etiology ; Death, Sudden, Cardiac/epidemiology ; Electrocardiography/methods ; Humans ; Hypokalemia/complications ; Kidney Diseases/complications ; Kidney Diseases/mortality ; Kinetics ; Long QT Syndrome/complications ; Long QT Syndrome/diagnosis ; Long QT Syndrome/mortality ; Magnesium/metabolism ; Myocardium/pathology ; Nephrology/methods ; Potassium/metabolism ; Renal Dialysis
    Chemical Substances Magnesium (I38ZP9992A) ; Potassium (RWP5GA015D)
    Language English
    Publishing date 2007-01
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 90594-x
    ISSN 1460-2385 ; 0931-0509
    ISSN (online) 1460-2385
    ISSN 0931-0509
    DOI 10.1093/ndt/gfl587
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    Zs.MO 329: Show issues

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  6. Book ; Online: Electrical Diseases of the Heart

    Gussak, Ihor / Antzelevitch, Charles

    Volume 1: Basic Foundations and Primary Electrical Diseases

    2013  

    Abstract: Electrical Disease of the Heart, 2nd Edition, volume 1, provides a valuable insight to the latest developments in the field of cardiac electrophysiology and clinical electrocardiology. Each chapter includes up-to-date results of studies aimed at ... ...

    Author's details edited by Ihor Gussak, Charles Antzelevitch
    Abstract Electrical Disease of the Heart, 2nd Edition, volume 1, provides a valuable insight to the latest developments in the field of cardiac electrophysiology and clinical electrocardiology. Each chapter includes up-to-date results of studies aimed at providing an understanding of the electrical function of the heart in health and disease, established and evidence-based knowledge of clinical outcomes, areas of controversy, and future trends. This book is highly relevant to a broad audience, ranging from medical and graduate students, to clinicians and scientists.

    The past two decades have witnessed an explosion of knowledge and radical changes in our understanding of the molecular, ionic, genetic, and pharmacologic basis of electrical diseases of the heart. Electrical diseases of the heart are heritable arrhythmogenic clinical entities that may share common clinical and genetic features, yet may be distinctly different in their genesis, prognosis, and management. Notably, both congenital and acquired electrical diseases of the heart are receiving increased recognition as a result of important advances in genetic analysis.  In this second edition of Electrical Diseases of the Heart, the Editors’ goal has been to embrace and highlight the explosion of knowledge that our field has witnessed since the publication of the first edition.  The approach continues to be one of bridging basic and clinical science in an attempt to advance meaningfully our understanding of heart disease and identify the knowledge gaps that exist. This volume covers the basic foundations and primary electrical diseases and with the companion volume provides the latest developments in the field of experimental and clinical cardiac electrophysiology, genetics, pharmacology and interventional therapies of various clinical arrhythmogenic entities. Residents, fellows and physicians in cardiology and electrophysiology will gain valuable insight into the latest developments in the field of cardiac electrophysiology and clinical electrocardiology by reading this book, including expert review of the genetic and epidemiologic considerations, diagnostic and therapeutic modalities of the newly discovered clinical syndromes and electrocardiographic phenomena, and their correlation with the most recent advances in the basic science
    Keywords Cardiology ; Epidemiology ; Internal medicine ; Medicine ; Neurology ; Medizin / Gesundheit # Innere Medizin ; Medizin / Gesundheit # Neurologie ; Medizin / Gesundheit # Sonstiges
    Language English
    Size Online-Ressource (XXI, 659 p. 201 illus., 98 illus. in color), digital
    Edition 2nd ed. 2013
    Publisher Springer
    Publishing place London
    Document type Book ; Online
    Note Description based upon print version of record
    ISBN 9781447148807 ; 9781447148814 ; 1447148800 ; 1447148819
    DOI 10.1007/978-1-4471-4881-4
    Database Former special subject collection: coastal and deep sea fishing

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  7. Book ; Online: Electrical Diseases of the Heart

    Gussak, Ihor / Antzelevitch, Charles

    Volume 2: Diagnosis and Treatment

    2013  

    Abstract: Electrical Disease of the Heart, 2nd Edition, volume 2, covers the diagnostic and treatment options available in the management of electrical diseases and with its companion volume provides the latest developments in the field of experimental and ... ...

    Author's details edited by Ihor Gussak, Charles Antzelevitch
    Abstract Electrical Disease of the Heart, 2nd Edition, volume 2, covers the diagnostic and treatment options available in the management of electrical diseases and with its companion volume provides the latest developments in the field of experimental and clinical cardiac electrophysiology, genetics, pharmacology and interventional therapies of various clinical arrhythmogenic entities. This book is highly relevant to a broad audience, ranging from medical and graduate students, to clinicians and scientists.

    The past two decades have witnessed an explosion of knowledge and radical changes in our understanding of the molecular, ionic, genetic, and pharmacologic basis of electrical diseases of the heart. Electrical diseases of the heart are heritable arrhythmogenic clinical entities that may share common clinical and genetic features, yet may be distinctly different in their genesis, prognosis, and management. Notably, both congenital and acquired electrical diseases of the heart are receiving increased recognition as a result of important advances in genetic analysis. In this second edition of Electrical Diseases of the Heart, the Editors’ goal has been to embrace and highlight the explosion of knowledge that our field has witnessed since the publication of the first edition.  The approach continues to be one of bridging basic and clinical science in an attempt to advance meaningfully our understanding of heart disease and identify the knowledge gaps that exist. This volume covers the diagnostic and treatment options available in the management of electrical diseases and with its companion volume provides the latest developments in the field of experimental and clinical cardiac electrophysiology, genetics, pharmacology and interventional therapies of various clinical arrhythmogenic entities. Residents, fellows and physicians in cardiology and electrophysiology will gain valuable insight into the latest developments in the field of cardiac electrophysiology and clinical electrocardiology by reading this book, including expert review of the genetic and epidemiologic considerations, diagnostic and therapeutic modalities of the newly discovered clinical syndromes and electrocardiographic phenomena, and their correlation with the most recent advances in the basic science
    Keywords Cardiology ; Epidemiology ; Internal medicine ; Medicine ; Neurology ; Medizin / Gesundheit Innere Medizin ; Medizin / Gesundheit Neurologie ; Medizin / Gesundheit Sonstiges
    Language English
    Size Online-Ressource (XXII, 682 p. 161 illus., 52 illus. in color), digital
    Edition 2nd ed. 2013
    Publisher Springer
    Publishing place London
    Document type Book ; Online
    Note Includes bibliographical references and index
    ISBN 9781447149774 ; 9781447149781 ; 1447149777 ; 1447149785
    DOI 10.1007/978-1-4471-4978-1
    Database Former special subject collection: coastal and deep sea fishing

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  8. Article ; Online: Clinical Significance of J Waves in Patients Undergoing Therapeutic Hypothermia for Out-of-Hospital Cardiac Arrest.

    Harhash, Ahmed / Gussak, Ihor / Cassuto, James / Winters, Stephen L

    Pacing and clinical electrophysiology : PACE

    2017  Volume 40, Issue 2, Page(s) 154–161

    Abstract: Background: Hypothermia is associated with the development of J waves. However, little is known about the impact of these electrocardiogram (ECG) findings on the development of ventricular arrhythmias and patient outcomes during therapeutic hypothermia ( ...

    Abstract Background: Hypothermia is associated with the development of J waves. However, little is known about the impact of these electrocardiogram (ECG) findings on the development of ventricular arrhythmias and patient outcomes during therapeutic hypothermia (TH) postresuscitation from out-of-hospital cardiac arrest (OHCA). We investigated the prevalence of J waves in OHCA patients prior to and during TH. Additionally, we explored the incidence of atrial and ventricular arrhythmias and in-hospital mortality for patients with and without J waves either at baseline, during TH, or both.
    Methods: We conducted a retrospective analysis of patients who suffered OHCA and underwent TH (goal temperature of 32-34°C). Fifty-nine patients were stratified dependent upon the presence of or the development of J waves on surface ECGs. Descriptive analysis and logistic regression modeling were used to assess the population differences and mortality, respectively, between patients who developed J waves during TH and those who did not.
    Results: There was no difference in the development of in-hospital atrial or ventricular arrhythmias between patients with J waves present during TH (16%) and those without (17.6%, P = 0.834). Compared to patients without J waves at baseline and during TH, those with J waves present both at baseline and during TH had significantly worse survival (hazard ratio = 12.42, P = 0.046).
    Conclusions: While J waves are common ECG findings during TH in patients resuscitated from OHCA, our study demonstrated an increase in mortality for patients with J waves present both at baseline and during TH.
    MeSH term(s) Arrhythmias, Cardiac/diagnosis ; Arrhythmias, Cardiac/etiology ; Electrocardiography/methods ; Emergency Medical Services/methods ; Female ; Heart Arrest/diagnosis ; Heart Arrest/prevention & control ; Humans ; Hypothermia, Induced/adverse effects ; Hypothermia, Induced/methods ; Male ; Middle Aged ; Retrospective Studies ; Treatment Outcome
    Language English
    Publishing date 2017-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 424437-0
    ISSN 1540-8159 ; 0147-8389
    ISSN (online) 1540-8159
    ISSN 0147-8389
    DOI 10.1111/pace.12988
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  9. Article ; Online: Short QT syndrome: a predictable story.

    Brugada, Josep / Gussak, Ihor / Brugada, Pedro

    Cardiology

    2014  Volume 128, Issue 3, Page(s) 231–233

    MeSH term(s) Anti-Arrhythmia Agents/therapeutic use ; Arrhythmias, Cardiac/diagnosis ; Arrhythmias, Cardiac/drug therapy ; Arrhythmias, Cardiac/genetics ; Death, Sudden, Cardiac/etiology ; Electrocardiography ; Female ; Humans ; Male ; Mutation/genetics ; Quinidine/therapeutic use ; Risk Factors ; Sotalol/therapeutic use
    Chemical Substances Anti-Arrhythmia Agents ; Sotalol (A6D97U294I) ; Quinidine (ITX08688JL)
    Language English
    Publishing date 2014
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 80092-2
    ISSN 1421-9751 ; 0008-6312
    ISSN (online) 1421-9751
    ISSN 0008-6312
    DOI 10.1159/000359995
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  10. Article ; Online: Short QT interval in clinical practice.

    Bjerregaard, Preben / Nallapaneni, Hari / Gussak, Ihor

    Journal of electrocardiology

    2010  Volume 43, Issue 5, Page(s) 390–395

    Abstract: The last ten years have seen a growing interest in clinical scenarios, where a short QT interval may play a role, especially because of an increased risk of sudden cardiac death in some situations. One such entity is Short QT Syndrome, which has emerged ... ...

    Abstract The last ten years have seen a growing interest in clinical scenarios, where a short QT interval may play a role, especially because of an increased risk of sudden cardiac death in some situations. One such entity is Short QT Syndrome, which has emerged as a rare, but very malignant disease, in particular when the QT interval is very short. A short QT interval has also been noticed in some patients with other arrhythmic syndromes such as Idiopathic Ventricular Fibrillation, Brugade Syndrome and Early Repolarization Syndrome, but the role of a short QT interval in these settings is so far not known. Hypercalcemia often leads to shortening of the QT interval, but there are no data in humans to suggest an increased risk of sudden cardiac death in this setting. In addition, a shorter-than-usual QT interval has been reported in patients with Chronic Fatigue Syndrome and in response to atropine, catecholamine and Hyperthermia. When a short QT interval is encountered in daily clinical practice, these various scenarios needs to be considered, but it is still not possible to come up with clear guidelines for how to work up and risk stratify such individuals. Genetic testing is only useful in very few and the value of an electrophysiologic study, Holter monitoring or stress testing to assess QT adaptation to heart rate and T wave morphology analysis may all be helpful, but not well-established, tests in this setting.
    MeSH term(s) Arrhythmias, Cardiac/complications ; Arrhythmias, Cardiac/diagnosis ; Arrhythmias, Cardiac/genetics ; Arrhythmias, Cardiac/physiopathology ; Death, Sudden, Cardiac/etiology ; Electrocardiography ; Electrophysiologic Techniques, Cardiac ; Genetic Testing ; Humans ; Risk Assessment ; Risk Factors
    Language English
    Publishing date 2010-09
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 410286-1
    ISSN 1532-8430 ; 0022-0736
    ISSN (online) 1532-8430
    ISSN 0022-0736
    DOI 10.1016/j.jelectrocard.2010.06.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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