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  1. Article ; Online: Long-term trends of COPD mortality: Gaps and opportunities.

    Mannino, David M / Tal-Singer, Ruth

    Respirology (Carlton, Vic.)

    2022  Volume 27, Issue 11, Page(s) 914–915

    MeSH term(s) Humans ; Pulmonary Disease, Chronic Obstructive/epidemiology ; Risk Factors
    Language English
    Publishing date 2022-08-02
    Publishing country Australia
    Document type Editorial ; Comment
    ZDB-ID 1435849-9
    ISSN 1440-1843 ; 1323-7799
    ISSN (online) 1440-1843
    ISSN 1323-7799
    DOI 10.1111/resp.14334
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    Zs.A 4957: Show issues Location:
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  2. Article ; Online: Managing Your Chronic Lung Disease during the COVID-19 Pandemic.

    Sockrider, Marianna / Tal-Singer, Ruth

    American journal of respiratory and critical care medicine

    2020  Volume 202, Issue 2, Page(s) P5–P6

    MeSH term(s) Betacoronavirus ; COVID-19 ; Chronic Disease ; Coronavirus Infections/complications ; Coronavirus Infections/epidemiology ; Coronavirus Infections/therapy ; Humans ; Lung Diseases/complications ; Lung Diseases/therapy ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/therapy ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-06-25
    Publishing country United States
    Document type Patient Education Handout
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.2020C8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: COPD at the Time of COVID-19: A COPD Foundation Perspective.

    Tal-Singer, Ruth / Crapo, James D

    Chronic obstructive pulmonary diseases (Miami, Fla.)

    2020  Volume 7, Issue 2, Page(s) 73–75

    Keywords covid19
    Language English
    Publishing date 2020-04-23
    Publishing country United States
    Document type Editorial
    ZDB-ID 2771715-X
    ISSN 2372-952X
    ISSN 2372-952X
    DOI 10.15326/jcopdf.7.2.2020.0149
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  5. Article: The COPD Foundation's COPD360Net Initiative Approach to Patient-Centric Drug Development: A Case Study in Using Patient Surveys to Inform New Treatments for Viral Respiratory Infections.

    Tal-Singer, Ruth / Miller, Bruce E / Rommes, Jean M / Luttmann, Mark A / Demaison, Christophe / Bradley Drummond, M / Pasquale, Cara B

    Journal of patient experience

    2023  Volume 10, Page(s) 23743735231151554

    Abstract: Patient-centric drug development is crucial to creating treatments that address unmet patient needs but is often ignored. The COPD Foundation's ... ...

    Abstract Patient-centric drug development is crucial to creating treatments that address unmet patient needs but is often ignored. The COPD Foundation's COPD360Net
    Language English
    Publishing date 2023-01-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2857285-3
    ISSN 2374-3743 ; 2374-3735
    ISSN (online) 2374-3743
    ISSN 2374-3735
    DOI 10.1177/23743735231151554
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  6. Article ; Online: Accelerated elastin degradation by age-disease interaction: a common feature in age-related diseases.

    Shek, Naomi / Choy, Anna-Maria / Lang, Chim C / Miller, Bruce E / Tal-Singer, Ruth / Bolton, Charlotte E / Thomson, Neil C / Chalmers, James D / Bown, Matt J / Newby, David E / Khan, Faisel / Huang, Jeffrey T J

    npj aging

    2024  Volume 10, Issue 1, Page(s) 15

    Abstract: Aging is a major driving force for many diseases but the relationship between chronological age, the aging process and age-related diseases is not fully understood. Fragmentation and loss of ultra-long-lived elastin are key features in aging and several ... ...

    Abstract Aging is a major driving force for many diseases but the relationship between chronological age, the aging process and age-related diseases is not fully understood. Fragmentation and loss of ultra-long-lived elastin are key features in aging and several age-related diseases leading to increased mortality. By comparing the relationship between age and elastin turnover with healthy volunteers, we show that accelerated elastin turnover by age-disease interaction is a common feature of age-related diseases.
    Language English
    Publishing date 2024-02-27
    Publishing country England
    Document type Journal Article
    ISSN 2731-6068
    ISSN (online) 2731-6068
    DOI 10.1038/s41514-024-00143-7
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  7. Article: New Adopters of Telemedicine During the Coronavirus-19 Pandemic in Respondents to an Online Community Survey: The Case for Access to Remote Management Tools for Individuals with Chronic Obstructive Pulmonary Disease.

    Boyce, Danielle M / Thomashow, Byron M / Sullivan, Jamie / Tal-Singer, Ruth

    Chronic obstructive pulmonary diseases (Miami, Fla.)

    2020  Volume 8, Issue 2, Page(s) 213–218

    Abstract: Objectives: To investigate telemedicine adoption, emergency department avoidance, and related characteristics of patients with chronic obstructive pulmonary disease (COPD) with and without exacerbations since the coronavirus 2019 (COVID-19) pandemic ... ...

    Abstract Objectives: To investigate telemedicine adoption, emergency department avoidance, and related characteristics of patients with chronic obstructive pulmonary disease (COPD) with and without exacerbations since the coronavirus 2019 (COVID-19) pandemic began.
    Methods: We conducted the second of a series of online surveys via SurveyMonkey.com of people with COPD between May 1, 2020 and May 31, 2020. Frequency, percentage, and Fisher's exact test (2-sided) were calculated using SPSS version 26.
    Results: More than half of respondents (157, 64%), indicated that they started using telemedicine in 2020. A total of 47% of respondents reported having had at least 1 exacerbation since January 1, 2020. Respondents who had at least 1 exacerbation in 2020 were more likely to start using telemedicine in 2020 than respondents who did not report any exacerbation in 2020 (75.7% versus 54.3%,
    Conclusions: In response to social distancing and other COVID-19 precautions, people with COPD are avoiding traditional, in-person health care environments and turning to telemedicine to prevent and manage exacerbations. Further investigation is needed to identify best practices in and barriers to telemedicine in this population.
    Language English
    Publishing date 2020-12-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2771715-X
    ISSN 2372-952X
    ISSN 2372-952X
    DOI 10.15326/jcopdf.2020.0181
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  8. Article ; Online: A rapidly changing understanding of COPD: World COPD Day from the COPD Foundation.

    Thomashow, Byron M / Mannino, David M / Tal-Singer, Ruth / Crapo, James D

    American journal of physiology. Lung cellular and molecular physiology

    2021  Volume 321, Issue 5, Page(s) L983–L987

    Abstract: World COPD Day raises awareness about chronic obstructive pulmonary disease (COPD). COPD accounts for over 150,000 US deaths per year. A major challenge is that COPD receives only a fraction of the research funding provided to other major diseases. ... ...

    Abstract World COPD Day raises awareness about chronic obstructive pulmonary disease (COPD). COPD accounts for over 150,000 US deaths per year. A major challenge is that COPD receives only a fraction of the research funding provided to other major diseases. Control of COPD is dependent on developing new approaches to diagnose the disease earlier with a recognition of either pre-COPD or established COPD based on symptoms, lung structural change and/or loss of lung function that occurs before meeting long established criteria for a population-based definition of obstruction. Optimization of current therapies improves lung function, exercise capacity, quality of life, and survival. New pathways of disease progression are being identified creating new opportunities for development of therapies that could stop or cure this disease.
    MeSH term(s) Adult ; Child ; Female ; Global Health ; Humans ; Infant, Newborn ; Pneumonia ; Pregnancy ; Premature Birth ; Pulmonary Disease, Chronic Obstructive/diagnosis ; Pulmonary Disease, Chronic Obstructive/epidemiology ; Pulmonary Disease, Chronic Obstructive/therapy ; Quality of Life
    Language English
    Publishing date 2021-10-06
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1013184-x
    ISSN 1522-1504 ; 1040-0605
    ISSN (online) 1522-1504
    ISSN 1040-0605
    DOI 10.1152/ajplung.00400.2021
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  10. Article ; Online: Evaluation of Over-the-Counter Portable Oxygen Concentrators Utilizing a Metabolic Simulator.

    Casaburi, Richard / Hess, Michael / Porszasz, Janos / Clark, William / Diesem, Ryan / Tal-Singer, Ruth / Ferguson, Carrie

    Respiratory care

    2022  Volume 68, Issue 4, Page(s) 445–451

    Abstract: Background: Supplemental oxygen is designed to raise alveolar P: Methods: A metabolic simulator, capable of simulating a range of metabolic rates and minute ventilations, determined effects of oxygen supplementation delivered by a variety of devices ... ...

    Abstract Background: Supplemental oxygen is designed to raise alveolar P
    Methods: A metabolic simulator, capable of simulating a range of metabolic rates and minute ventilations, determined effects of oxygen supplementation delivered by a variety of devices on alveolar P
    Results: Continuous-flow tank oxygen yielded a linear P
    Conclusions: Only one of 3 OTC POCs tested was potentially of use by patients requiring ambulatory oxygen. Physicians and respiratory therapists should inform patients requiring portable oxygen that OTC devices may not meet their oxygenation requirements.
    MeSH term(s) Humans ; Pulmonary Disease, Chronic Obstructive/therapy ; Oxygen Inhalation Therapy ; Oxygen ; Lung ; Respiratory Physiological Phenomena
    Chemical Substances Oxygen (S88TT14065)
    Language English
    Publishing date 2022-11-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603252-7
    ISSN 1943-3654 ; 0098-9142 ; 0020-1324
    ISSN (online) 1943-3654
    ISSN 0098-9142 ; 0020-1324
    DOI 10.4187/respcare.10495
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