LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 200

Search options

  1. Article ; Online: Semi-supervised segmentation of orbit in CT images with paired copy-paste strategy.

    Li, Wentao / Song, Hong / Ai, Danni / Shi, Jieliang / Wang, Yuanyuan / Wu, Wencan / Yang, Jian

    Computers in biology and medicine

    2024  Volume 171, Page(s) 108176

    Abstract: The segmentation of the orbit in computed tomography (CT) images plays a crucial role in facilitating the quantitative analysis of orbital decompression surgery for patients with Thyroid-associated Ophthalmopathy (TAO). However, the task of orbit ... ...

    Abstract The segmentation of the orbit in computed tomography (CT) images plays a crucial role in facilitating the quantitative analysis of orbital decompression surgery for patients with Thyroid-associated Ophthalmopathy (TAO). However, the task of orbit segmentation, particularly in postoperative images, remains challenging due to the significant shape variation and limited amount of labeled data. In this paper, we present a two-stage semi-supervised framework for the automatic segmentation of the orbit in both preoperative and postoperative images, which consists of a pseudo-label generation stage and a semi-supervised segmentation stage. A Paired Copy-Paste strategy is concurrently introduced to proficiently amalgamate features extracted from both preoperative and postoperative images, thereby augmenting the network discriminative capability in discerning changes within orbital boundaries. More specifically, we employ a random cropping technique to transfer regions from labeled preoperative images (foreground) onto unlabeled postoperative images (background), as well as unlabeled preoperative images (foreground) onto labeled postoperative images (background). It is imperative to acknowledge that every set of preoperative and postoperative images belongs to the identical patient. The semi-supervised segmentation network (stage 2) utilizes a combination of mixed supervisory signals from pseudo labels (stage 1) and ground truth to process the two mixed images. The training and testing of the proposed method have been conducted on the CT dataset obtained from the Eye Hospital of Wenzhou Medical University. The experimental results demonstrate that the proposed method achieves a mean Dice similarity coefficient (DSC) of 91.92% with only 5% labeled data, surpassing the performance of the current state-of-the-art method by 2.4%.
    MeSH term(s) Humans ; Orbit/diagnostic imaging ; Orbit/surgery ; Hospitals ; Tomography, X-Ray Computed ; Universities ; Image Processing, Computer-Assisted
    Language English
    Publishing date 2024-02-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 127557-4
    ISSN 1879-0534 ; 0010-4825
    ISSN (online) 1879-0534
    ISSN 0010-4825
    DOI 10.1016/j.compbiomed.2024.108176
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Life's Essential 8 and osteoporosis in adults aged 50 years or older: data from the National Health and Nutrition Examination Survey.

    Tang, Yuchen / Dong, Wei / Shen, Jieliang / Jiang, Guanyin / Wang, Qiufu / Hao, Jie / Hu, Zhenming

    Archives of osteoporosis

    2024  Volume 19, Issue 1, Page(s) 13

    Abstract: In this cross-sectional study, we examined the association between Life's Essential 8 (LE8) and bone mineral density (BMD) as well as osteoporosis risk among adults aged 50 and over. The findings of this study revealed that higher LE8 scores were ... ...

    Abstract In this cross-sectional study, we examined the association between Life's Essential 8 (LE8) and bone mineral density (BMD) as well as osteoporosis risk among adults aged 50 and over. The findings of this study revealed that higher LE8 scores were associated with higher BMD and reduced osteoporosis risk.
    Purpose: The objective of the present study was to evaluate the association between Life's Essential 8 (LE8) and bone mineral density (BMD), as well as osteoporosis risk, in adults aged 50 years or over.
    Methods: This cross-sectional study recruited individuals who were 50 years old or older from the National Health and Nutrition Examination Survey. LE8 scores were evaluated and calculated according to the scoring algorithm based on the American Heart Association recommendations, which were further categorized into health behaviors (LE8-HB) and health factors (LE8-HF) scores. Furthermore, the present study utilized multivariate linear regression models to examine the correlations between BMD and LE8 scores. In addition, ordinal logistic regression models were employed to determine the associations between the risk of osteoporosis (normal BMD, osteopenia, and osteoporosis) and LE8 scores.
    Results: The final analysis included a total of 2910 participants, whose mean age was 64.49 ± 9.28 years. LE8 and LE8-HF scores exhibited a negative association with BMD and a positive association with osteoporosis risk in unadjusted models. Nevertheless, after adjustment for covariates, LE8 and LE8-HB scores exhibited a positive association with BMD and a negative association with osteoporosis risk, regardless of age, sex, or menopausal status.
    Conclusions: Scoring systems based on multiple lifestyle and behavior factors, similar to LE8, have the potential to become a novel option and be used for osteoporosis risk assessment.
    MeSH term(s) Adult ; United States/epidemiology ; Humans ; Middle Aged ; Aged ; Nutrition Surveys ; Cross-Sectional Studies ; Absorptiometry, Photon ; Osteoporosis/complications ; Bone Density ; Risk Factors
    Language English
    Publishing date 2024-02-16
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2253231-6
    ISSN 1862-3514 ; 1862-3522
    ISSN (online) 1862-3514
    ISSN 1862-3522
    DOI 10.1007/s11657-024-01368-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Effects of Intestinal Microbiota on the Biological Transformation of Arsenic in Zebrafish: Contribution and Mechanism.

    Zhong, Xiaoting / Zhang, Guiwei / Huang, Jieliang / Chen, Linkang / Shi, Yingying / Wang, Dongbin / Zheng, Qiuyi / Su, Hongtian / Li, Xiang / Wang, Chunchun / Zhang, Jingjing / Guo, Lianxian

    Environmental science & technology

    2024  Volume 58, Issue 5, Page(s) 2247–2259

    Abstract: Both the gut microbiome and their host participate in arsenic (As) biotransformation, while their exact roles and ... ...

    Abstract Both the gut microbiome and their host participate in arsenic (As) biotransformation, while their exact roles and mechanisms
    MeSH term(s) Animals ; Arsenic ; Gastrointestinal Microbiome ; Zebrafish ; Liver/metabolism ; Biotransformation ; Methyltransferases/genetics ; Methyltransferases/metabolism
    Chemical Substances Arsenic (N712M78A8G) ; Methyltransferases (EC 2.1.1.-)
    Language English
    Publishing date 2024-01-05
    Publishing country United States
    Document type Journal Article
    ISSN 1520-5851
    ISSN (online) 1520-5851
    DOI 10.1021/acs.est.3c08010
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: Structural stabilization of honeybee wings based on heterogeneous stiffness.

    Yu, Li / Zhao, Jieliang / Wang, Wenzhong / Zong, Le / Ge, Siqin / Yan, Shaoze

    Soft matter

    2023  Volume 19, Issue 5, Page(s) 841–850

    Abstract: Structural stabilization for a membrane structure under high-frequency vibration is still a recognized problem. In nature, honeybee wings with non-uniform material properties demonstrate excellent anti-interference ability. However, the correlation ... ...

    Abstract Structural stabilization for a membrane structure under high-frequency vibration is still a recognized problem. In nature, honeybee wings with non-uniform material properties demonstrate excellent anti-interference ability. However, the correlation between the structural stabilization and mechanical properties of insect wings has not been completely verified. Here we demonstrate that the sclerotization diversity partially distinguishes the stiffness inhomogeneity of the wing structure. Furthermore, a wing cross-section model with diversity in elastic modulus is constructed to analyze the effect of stiffness distribution on stress optimization during flight. Our results demonstrate that the heterogeneous stiffness promotes the stress distribution and structural stabilization of the wing during flight, which may inspire more optimal designs for anisotropic high-strength membrane structures.
    MeSH term(s) Bees ; Animals ; Flight, Animal ; Insecta ; Elastic Modulus ; Wings, Animal ; Anisotropy ; Biomechanical Phenomena ; Models, Biological
    Language English
    Publishing date 2023-02-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 2191476-X
    ISSN 1744-6848 ; 1744-683X
    ISSN (online) 1744-6848
    ISSN 1744-683X
    DOI 10.1039/d2sm01353c
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article: Nectar Feeding by a Honey Bee's Hairy Tongue: Morphology, Dynamics, and Energy-Saving Strategies.

    Wang, Hao / Wu, Zhigang / Zhao, Jieliang / Wu, Jianing

    Insects

    2021  Volume 12, Issue 9

    Abstract: Most flower-visiting insects have evolved highly specialized morphological structures to facilitate nectar feeding. As a typical pollinator, the honey bee has specialized mouth parts comprised of a pair of galeae, a pair of labial palpi, and a glossa, to ...

    Abstract Most flower-visiting insects have evolved highly specialized morphological structures to facilitate nectar feeding. As a typical pollinator, the honey bee has specialized mouth parts comprised of a pair of galeae, a pair of labial palpi, and a glossa, to feed on the nectar by the feeding modes of lapping or sucking. To extensively elucidate the mechanism of a bee's feeding, we should combine the investigations from glossa morphology, feeding behaviour, and mathematical models. This paper reviews the interdisciplinary research on nectar feeding behaviour of honey bees ranging from morphology, dynamics, and energy-saving strategies, which may not only reveal the mechanism of nectar feeding by honey bees but inspire engineered facilities for microfluidic transport.
    Language English
    Publishing date 2021-08-24
    Publishing country Switzerland
    Document type Journal Article ; Review
    ISSN 2075-4450
    ISSN 2075-4450
    DOI 10.3390/insects12090762
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: Nectar Feeding by a Honey Bee’s Hairy Tongue

    Hao Wang / Zhigang Wu / Jieliang Zhao / Jianing Wu

    Insects, Vol 12, Iss 762, p

    Morphology, Dynamics, and Energy-Saving Strategies

    2021  Volume 762

    Abstract: Most flower-visiting insects have evolved highly specialized morphological structures to facilitate nectar feeding. As a typical pollinator, the honey bee has specialized mouth parts comprised of a pair of galeae, a pair of labial palpi, and a glossa, to ...

    Abstract Most flower-visiting insects have evolved highly specialized morphological structures to facilitate nectar feeding. As a typical pollinator, the honey bee has specialized mouth parts comprised of a pair of galeae, a pair of labial palpi, and a glossa, to feed on the nectar by the feeding modes of lapping or sucking. To extensively elucidate the mechanism of a bee’s feeding, we should combine the investigations from glossa morphology, feeding behaviour, and mathematical models. This paper reviews the interdisciplinary research on nectar feeding behaviour of honey bees ranging from morphology, dynamics, and energy-saving strategies, which may not only reveal the mechanism of nectar feeding by honey bees but inspire engineered facilities for microfluidic transport.
    Keywords honey bee ; mouth parts anatomy ; nectar feeding behaviour ; dynamics ; energy-saving strategies ; Science ; Q
    Language English
    Publishing date 2021-08-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  7. Article ; Online: Plantamajoside promotes metformin-induced apoptosis, autophagy and proliferation arrest of liver cancer cells via suppressing Akt/GSK3β signaling.

    Wang, Zhuo / Zuo, Jieliang / Zhang, Linlin / Zhang, Zhenghua / Wei, Yongpeng

    Human & experimental toxicology

    2022  Volume 41, Page(s) 9603271221078868

    Abstract: Metformin, a well-known antidiabetic drug, exhibits anticancer effect in a variety of cancers, including liver cancer. Plantamajoside (PMS), a phenylethanoid glycoside compound isolated from Plantago asiatica, is proved to possess anticancer effects, too. ...

    Abstract Metformin, a well-known antidiabetic drug, exhibits anticancer effect in a variety of cancers, including liver cancer. Plantamajoside (PMS), a phenylethanoid glycoside compound isolated from Plantago asiatica, is proved to possess anticancer effects, too. In our study, we hypothesized that PMS might promote metformin mediated anticancer effects on liver cancer. The half maximal inhibitory concentration (IC
    MeSH term(s) Animals ; Apoptosis ; Autophagy ; Catechols ; Cell Movement ; Cell Proliferation ; Glucosides ; Glycogen Synthase Kinase 3 beta/metabolism ; Hep G2 Cells ; Humans ; Liver Neoplasms/drug therapy ; Liver Neoplasms/metabolism ; Metformin/pharmacology ; Metformin/therapeutic use ; Mice ; Proto-Oncogene Proteins c-akt/metabolism
    Chemical Substances Catechols ; Glucosides ; plantamajoside (104777-68-6) ; Metformin (9100L32L2N) ; Glycogen Synthase Kinase 3 beta (EC 2.7.11.1) ; Proto-Oncogene Proteins c-akt (EC 2.7.11.1)
    Language English
    Publishing date 2022-03-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 1027454-6
    ISSN 1477-0903 ; 0144-5952 ; 0960-3271
    ISSN (online) 1477-0903
    ISSN 0144-5952 ; 0960-3271
    DOI 10.1177/09603271221078868
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: A systematic review and meta-analysis of cemented and uncemented bipolar hemiarthroplasty for the treatment of femoral neck fractures in elderly patients over 60 years old

    Mengyu Fu / Jieliang Shen / Zhoukui Ren / Yingwen Lv / Jiangang Wang / Wei Jiang

    Frontiers in Medicine, Vol

    2023  Volume 10

    Abstract: BackgroundCurrently, whether bone cement can be applied in bipolar hemiarthroplasty to treat femoral neck fractures (FNFs) in elderly patients is controversial. The aim of this systematic review and meta-analysis was to compare the effectiveness and ... ...

    Abstract BackgroundCurrently, whether bone cement can be applied in bipolar hemiarthroplasty to treat femoral neck fractures (FNFs) in elderly patients is controversial. The aim of this systematic review and meta-analysis was to compare the effectiveness and safety of cemented bipolar hemiarthroplasty (CBH) versus uncemented bipolar hemiarthroplasty (UCBH) in the treatment of FNFs among elderly patients over 60 years old.Materials and methodsThe Pubmed, Web of science, Cochrane Library and EMBASE databases were searched comprehensively for relevant articles from their inception to May 2022. Studies about comparing outcomes between CBH and UCBH for FNFs in elderly patients aged more than 60 years were included. Outcomes including operation time, intra-operative blood loss, length of hospital stay, wound infections, residual pain, revisions, re-operations, complications related to prosthesis, general complications, and mortality. The Review Manager 5.3 software provided by the Cochrane Collaboration Network was used to perform the meta-analysis of comparable data.ResultsA total of 6 randomized controlled trials (RCTs) and 9 observational studies were included in this analysis, with 33,118 patients (33,127 hips). Results of the meta-analysis indicated that the operation time [WMD = 13.01 min, 95% CI (10.79, 15.23)], intra-operative blood loss [WMD = 80.57 ml, 95% CI (61.14, 99.99)], incidence of heterotrophic ossification [OR = 2.07, 95% CI (1,14, 3.78)], were increased in the CBH group but the incidence of intra-operative fractures [OR = 0.24, 95% CI (0.07, 0.86)], periprosthetic fractures [OR = 0.24, 95% CI (0.18, 0.31)], aseptic loosening of prosthesis [OR = 0.20, 95% CI (0.09, 0.44)], wound infections [OR = 0.80, 95% CI (0.68, 0.95)] and re-operation rates [OR = 0.61, 95% CI (0.54, 0.68)] were lower in the CBH group by comparison with the UCHB group. However, there were no significant differences in residual pain, length of hospital stay, prosthetic dislocation, prosthetic subsidence (> 5 mm), acetabulum erosion, ...
    Keywords femoral neck fractures ; elderly patients ; cemented ; uncemented ; bipolar hemiarthroplasty ; meta-analysis ; Medicine (General) ; R5-920
    Subject code 610
    Language English
    Publishing date 2023-02-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  9. Article: Nectar Feeding by a Honey Bee’s Hairy Tongue: Morphology, Dynamics, and Energy-Saving Strategies

    Wang, Hao / Wu, Zhigang / Zhao, Jieliang / Wu, Jianing

    Insects. 2021 Aug. 24, v. 12, no. 9

    2021  

    Abstract: Most flower-visiting insects have evolved highly specialized morphological structures to facilitate nectar feeding. As a typical pollinator, the honey bee has specialized mouth parts comprised of a pair of galeae, a pair of labial palpi, and a glossa, to ...

    Abstract Most flower-visiting insects have evolved highly specialized morphological structures to facilitate nectar feeding. As a typical pollinator, the honey bee has specialized mouth parts comprised of a pair of galeae, a pair of labial palpi, and a glossa, to feed on the nectar by the feeding modes of lapping or sucking. To extensively elucidate the mechanism of a bee’s feeding, we should combine the investigations from glossa morphology, feeding behaviour, and mathematical models. This paper reviews the interdisciplinary research on nectar feeding behaviour of honey bees ranging from morphology, dynamics, and energy-saving strategies, which may not only reveal the mechanism of nectar feeding by honey bees but inspire engineered facilities for microfluidic transport.
    Keywords energy conservation ; honey ; honey bees ; interdisciplinary research ; mouth ; nectar ; nectar feeding ; palps ; pollinators
    Language English
    Dates of publication 2021-0824
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    ZDB-ID 2662247-6
    ISSN 2075-4450
    ISSN 2075-4450
    DOI 10.3390/insects12090762
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

  10. Article: A systematic review and meta-analysis of cemented and uncemented bipolar hemiarthroplasty for the treatment of femoral neck fractures in elderly patients over 60 years old.

    Fu, Mengyu / Shen, Jieliang / Ren, Zhoukui / Lv, Yingwen / Wang, Jiangang / Jiang, Wei

    Frontiers in medicine

    2023  Volume 10, Page(s) 1085485

    Abstract: Background: Currently, whether bone cement can be applied in bipolar hemiarthroplasty to treat femoral neck fractures (FNFs) in elderly patients is controversial. The aim of this systematic review and meta-analysis was to compare the effectiveness and ... ...

    Abstract Background: Currently, whether bone cement can be applied in bipolar hemiarthroplasty to treat femoral neck fractures (FNFs) in elderly patients is controversial. The aim of this systematic review and meta-analysis was to compare the effectiveness and safety of cemented bipolar hemiarthroplasty (CBH) versus uncemented bipolar hemiarthroplasty (UCBH) in the treatment of FNFs among elderly patients over 60 years old.
    Materials and methods: The Pubmed, Web of science, Cochrane Library and EMBASE databases were searched comprehensively for relevant articles from their inception to May 2022. Studies about comparing outcomes between CBH and UCBH for FNFs in elderly patients aged more than 60 years were included. Outcomes including operation time, intra-operative blood loss, length of hospital stay, wound infections, residual pain, revisions, re-operations, complications related to prosthesis, general complications, and mortality. The Review Manager 5.3 software provided by the Cochrane Collaboration Network was used to perform the meta-analysis of comparable data.
    Results: A total of 6 randomized controlled trials (RCTs) and 9 observational studies were included in this analysis, with 33,118 patients (33,127 hips). Results of the meta-analysis indicated that the operation time [WMD = 13.01 min, 95% CI (10.79, 15.23)], intra-operative blood loss [WMD = 80.57 ml, 95% CI (61.14, 99.99)], incidence of heterotrophic ossification [OR = 2.07, 95% CI (1,14, 3.78)], were increased in the CBH group but the incidence of intra-operative fractures [OR = 0.24, 95% CI (0.07, 0.86)], periprosthetic fractures [OR = 0.24, 95% CI (0.18, 0.31)], aseptic loosening of prosthesis [OR = 0.20, 95% CI (0.09, 0.44)], wound infections [OR = 0.80, 95% CI (0.68, 0.95)] and re-operation rates [OR = 0.61, 95% CI (0.54, 0.68)] were lower in the CBH group by comparison with the UCHB group. However, there were no significant differences in residual pain, length of hospital stay, prosthetic dislocation, prosthetic subsidence (> 5 mm), acetabulum erosion, revisions, pulmonary infections, pulmonary embolisms, urinary tract infections, deep venous thromboses, decubitus, cardiovascular accidents (arrhythmia/myocardial infarction), and respiratory failure between the two groups. In terms of mortality, perioperative mortality (within 72 h) [OR = 2.39, 95% CI (1.71, 3.32)] and 1-week mortality postoperatively [OR = 1.22, 95% CI (1.05, 1.41)] in CBH group were higher than those in UCBH group, but there were no significant differences in mortality at 1 month, 3 months, 1 year, and 2 years postoperatively between CBH group and UCBH group.
    Conclusion: This meta-analysis found that elderly patients over 60 years old with FNFs who underwent CBH had longer operation time, higher incidence of heterotrophic ossification, intra-operative blood loss, and mortality within 72 h of operation and at 1-week postoperatively, but lower incidence of periprosthetic fractures, aseptic loosening of prosthesis, intra-operative fractures, wound infections and re-operations. Other outcomes were not significantly different between the two groups.
    Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/, identifier CRD42021274253.
    Language English
    Publishing date 2023-02-02
    Publishing country Switzerland
    Document type Systematic Review
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2023.1085485
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top