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  1. Article ; Online: The COVID-19 and Saliva Paradox.

    Serafim Vilela, Ana Carolina / Costa, Nádia Lago

    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons

    2020  Volume 78, Issue 12, Page(s) 2105

    MeSH term(s) COVID-19 ; Delivery of Health Care ; Humans ; Oral and Maxillofacial Surgeons ; Pandemics ; Patients ; SARS-CoV-2 ; Saliva ; Solutions
    Chemical Substances Solutions
    Keywords covid19
    Language English
    Publishing date 2020-09-19
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 392404-x
    ISSN 1531-5053 ; 0278-2391
    ISSN (online) 1531-5053
    ISSN 0278-2391
    DOI 10.1016/j.joms.2020.07.225
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The COVID-19 and Saliva Paradox

    Serafim Vilela, Ana Carolina / Costa, Nádia Lago

    Journal of Oral and Maxillofacial Surgery ; ISSN 0278-2391

    2020  

    Keywords Surgery ; Oral Surgery ; Otorhinolaryngology ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    DOI 10.1016/j.joms.2020.07.225
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Poor oral health status and adverse COVID-19 outcomes: A preliminary study in hospitalized patients.

    Costa, Camila Alves / Vilela, Ana Carolina Serafim / Oliveira, Suzane Aparecida / Gomes, Tiago Dias / Andrade, Alex Alves Costa / Leles, Cláudio Rodrigues / Costa, Nádia Lago

    Journal of periodontology

    2022  

    Abstract: Background: Most of the common risk factors for severe outcomes of coronavirus disease 2019 (COVID-19) are correlated with poor oral health, tooth loss, and periodontitis. This has pointed to a possible relationship between oral and systemic health in ... ...

    Abstract Background: Most of the common risk factors for severe outcomes of coronavirus disease 2019 (COVID-19) are correlated with poor oral health, tooth loss, and periodontitis. This has pointed to a possible relationship between oral and systemic health in COVID-19 patients. Hence, this study aimed to assess the dental and periodontal status of hospitalized COVID-19 patients and their associations with the incidence of adverse COVID-19 outcomes.
    Methods: We included 128 hospital patients aged between 20 and 97 years and with diagnoses of COVID-19 in this prospective observational study. Dental and periodontal status was assessed using in-hospital clinical examinations, including the Decayed, Missing, and Filled Teeth index, periodontal status, and tooth loss patterns (Eichner index). Associations between oral health measures, the severity of COVID-19 symptoms, and hospitalization endpoints were tested using chi-square test and incidence rate ratio (IRR) estimation using a generalized linear model with log-Poisson regression. The regression models used a block-wise selection of predictors for oral health-related variables, comorbidities, and patients' ages.
    Results: Overall, poor oral health conditions were highly prevalent and associated with critical COVID-19 symptoms, higher risk for admission in the intensive care unit (ICU), and death. Periodontitis was significantly associated with ICU admission (IRR = 1.44; 95% confidence interval [95%CI] = 1.07-1.95; P = 0.017), critical symptoms (IRR = 2.56; 95%CI = 1.44-4.55; P = 0.001), and risk of death (IRR = 2.05; 95%CI = 1.12-3.76; P = 0.020) when adjusted for age and comorbidities. The Eichner index (classes B and C) was associated with ICU admission.
    Conclusion: There was a positive association between deleterious oral health-related conditions, especially periodontitis, and severe COVID-19 outcomes in hospitalized COVID-19 patients.
    Language English
    Publishing date 2022-03-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 390921-9
    ISSN 1943-3670 ; 0022-3492 ; 1049-8885 ; 0095-960X
    ISSN (online) 1943-3670
    ISSN 0022-3492 ; 1049-8885 ; 0095-960X
    DOI 10.1002/JPER.21-0624
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ul III Zs.146: Show issues Location:
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  5. Article ; Online: Validity and reliability of immunochromatographic IgM/IgG rapid tests for COVID-19 salivary diagnosis.

    Vilela, Ana Carolina Serafim / Costa, Camila Alves / Oliveira, Suzane Aparecida / Souza, Menira Borges Lima Dias / Fiaccadori, Fabiola Souza / Leles, Cláudio Rodrigues / Costa, Nádia Lago

    Oral diseases

    2021  Volume 28 Suppl 2, Page(s) 2465–2473

    Abstract: Objectives: To assess the accuracy of three immunochromatographic rapid tests for salivary detection of immunoglobulin M (IgM) and immunoglobulin G (IgG) antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antigens and the ... ...

    Abstract Objectives: To assess the accuracy of three immunochromatographic rapid tests for salivary detection of immunoglobulin M (IgM) and immunoglobulin G (IgG) antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antigens and the reliability of these tests comparing saliva with plasma samples.
    Materials and methods: Plasma and saliva samples from 62 patients diagnosed with coronavirus disease 2019 (COVID-19) and 20 healthy volunteers were assayed. IgM/IgG antibody against SARS-COV-2 was detected using three immunochromatographic rapid tests and compared with real-time reverse transcription-polymerase chain reaction (qRT-PCR).
    Results: The tests' overall accuracy for detecting anti-SARS-CoV-2 antibodies ranged from 75.6 to 79.3 for saliva and 86.6-87.8 for plasma tests. The sensitivity of saliva and plasma tests increased with the severity of COVID-19 signs and symptoms. The chance of a positive plasma test in participants with a positive qRT-PCR test was 2.27 greater than a positive saliva test.
    Conclusions: Although rapid immunochromatographic tests are more accurate using plasma than saliva, which was expected considering its original use, our findings support the use of saliva as a straightforward supplementary method to assess seroconversion in patients with COVID-19, with important sensitivity and sensibility, especially in severe and critical cases.
    MeSH term(s) Humans ; COVID-19/diagnosis ; Immunoglobulin G ; SARS-CoV-2 ; Reproducibility of Results ; Immunoglobulin M/analysis ; Sensitivity and Specificity
    Chemical Substances Immunoglobulin G ; Immunoglobulin M
    Language English
    Publishing date 2021-11-03
    Publishing country Denmark
    Document type Journal Article
    ZDB-ID 1290529-x
    ISSN 1601-0825 ; 1354-523X
    ISSN (online) 1601-0825
    ISSN 1354-523X
    DOI 10.1111/odi.14059
    Database MEDical Literature Analysis and Retrieval System OnLINE

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