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  1. Book ; Online ; E-Book: Aspiration Pneumonia

    Teramoto, Shinji / Komiya, Kosaku

    The Current Clinical Giant for Respiratory Physicians

    (Respiratory Disease Series: Diagnostic Tools and Disease Managements,)

    2020  

    Abstract: This book offers an essential overview of aspiration pneumonia, and focuses on four major aspects: epidemiology, pathophysiology, new preventive strategies, and trending topics. Each part presents detailed findings and insights into critical issues for ... ...

    Author's details edited by Shinji Teramoto, Kosaku Komiya
    Series title Respiratory Disease Series: Diagnostic Tools and Disease Managements,
    Abstract This book offers an essential overview of aspiration pneumonia, and focuses on four major aspects: epidemiology, pathophysiology, new preventive strategies, and trending topics. Each part presents detailed findings and insights into critical issues for the treatment of the disease including its diagnosis, assessment, selecting antibiotics, similarities and differences between aspiration risk and aspiration pneumonia risk, different therapeutic approaches and so on. The book also discusses emerging topics concerning the definition of NHCAP and sleep apnea. Special attention is given to therapeutic and preventive approaches for the elderly, highlighting recent advances and the evidence on their positive outcomes. Since the patients with this disorder are often in a post-stroke state and elderly, the book is highly relevant for neurologists and geriatric physicians. Further, many surgeons also face this type of pneumonia in association with postoperative complications and cancer therapy related complications. Lastly, the definition of aspiration pneumonia and its therapeutic strategy have yet to be established in many countries, and the data presented here should serve as a guideline for its future diagnosis and treatment. As such, the book offers a valuable resource for primary physicians, pulmonologists, gerontologists, respiratory nurses, physical therapists, dentists and otolaryngologists alike.
    Keywords Respiratory organs—Diseases ; Geriatrics ; Pneumology/Respiratory System ; Geriatrics/Gerontology ; Pneumònia ; Malalties de l'aparell respiratori ; Pneumologia
    Subject code 616.241
    Language English
    Size 1 online resource (232 pages).
    Edition 1st ed. 2020.
    Publisher Springer Singapore ; Imprint: Springer
    Publishing place Singapore
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 981-15-4506-5 ; 981-15-4505-7 ; 978-981-15-4506-1 ; 978-981-15-4505-4
    DOI 10.1007/978-981-15-4506-1
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Prevalence of aspiration pneumonitis not requiring antibiotics among patients with aspiration pneumonia.

    Goto, Akihiko / Komiya, Kosaku / Kadota, Jun-Ichi

    Geriatrics & gerontology international

    2023  Volume 23, Issue 10, Page(s) 760–761

    Language English
    Publishing date 2023-08-29
    Publishing country Japan
    Document type Letter
    ZDB-ID 2113849-7
    ISSN 1447-0594 ; 1444-1586
    ISSN (online) 1447-0594
    ISSN 1444-1586
    DOI 10.1111/ggi.14656
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Pneumocystis jirovecii Pneumonia in a Patient With Localized Mycosis Fungoides Not Receiving Immunosuppressive Treatment.

    Kudoh, Ryohei / Komiya, Kosaku / Takaki, Ryuichiro / Yokoyama, Atsushi / Hiramatsu, Kazufumi / Kadota, Jun-Ichi

    Cureus

    2024  Volume 16, Issue 1, Page(s) e51724

    Abstract: Pneumocystis ... ...

    Abstract Pneumocystis jirovecii
    Language English
    Publishing date 2024-01-05
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.51724
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  4. Article: Do Large Ears Have an Advantage in Preventing Airborne Transmission?

    Kosaku, Komiya / Hiramatsu, Kazufumi / Kadota, Jun-Ichi

    Cureus

    2022  Volume 14, Issue 10, Page(s) e30335

    Abstract: Although double masking provides better protection against COVID-19 than single masking, the exact number of masks needed to achieve the most significant protection has not been determined to date. The present study investigated the changes in leakage ... ...

    Abstract Although double masking provides better protection against COVID-19 than single masking, the exact number of masks needed to achieve the most significant protection has not been determined to date. The present study investigated the changes in leakage with the use of surgical masks in a healthy person in terms of the number of masks. When the number of masks reached the upper limit that could be worn on the ears, large plastic ear attachments were used for each ear. The leakage rate related to the use of a single mask was approximately 50%, and with two masks, it was significantly reduced to approximately 30%. However, the leakage rate increased to approximately 45% with the use of three and four masks. When more than four masks were worn, the rate gradually decreased. Conversely, the rate for three-seven masks was not significantly lower than that for two masks. Although individuals with large ears might be able to wear more than five masks, the use of more than two masks would not be significantly better than the use of two masks.
    Language English
    Publishing date 2022-10-15
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.30335
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  5. Article ; Online: Impact of Antibiotics Used for Acute Aspiration Bronchitis on the Prevention of Pneumonia.

    Goto, Akihiko / Komiya, Kosaku / Umeki, Kenji / Hiramatsu, Kazufumi / Kadota, Jun-Ichi

    Geriatrics (Basel, Switzerland)

    2024  Volume 9, Issue 2

    Abstract: Backgrounds: It remains unclear if antibiotics should be used for the treatment of acute aspiration bronchitis to prevent the development of pneumonia. This study aimed to assess the associations between the use of antibiotics and the development of ... ...

    Abstract Backgrounds: It remains unclear if antibiotics should be used for the treatment of acute aspiration bronchitis to prevent the development of pneumonia. This study aimed to assess the associations between the use of antibiotics and the development of pneumonia among patients with acute aspiration bronchitis.
    Methods: We retrospectively reviewed consecutive patients with acute aspiration bronchitis aged ≥75 years. Acute aspiration bronchitis was defined as a condition with aspiration risk, high fever (body temperature, ≥37.5 °C), respiratory symptoms, and the absence of evidence of pneumonia.
    Results: There was no significant difference in the incidence of pneumonia between patients treated with and without antibiotics for acute aspiration bronchitis (6/44, 14% vs. 31/143, 22%;
    Conclusions: Antibiotic administration should not be routinely recommended to prevent pneumonia following acute aspiration bronchitis, and patients with decreased renal function should be closely monitored. A randomized controlled trial is necessary to validate these results.
    Language English
    Publishing date 2024-02-25
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2308-3417
    ISSN (online) 2308-3417
    DOI 10.3390/geriatrics9020026
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Carbapenem vs. non-carbapenem antibiotics for ventilator-associated pneumonia: A systematic review with meta-analysis.

    Shuto, Hisayuki / Komiya, Kosaku / Tone, Kazuya / Matsumoto, Hiroyuki / Moro, Hiroshi / Shime, Nobuaki

    Respiratory investigation

    2024  Volume 62, Issue 2, Page(s) 200–205

    Abstract: Background: Carbapenem is recommended as one of the first-line regimens for ventilator-associated pneumonia (VAP), but no recent systematic review has fully investigated its efficacy. This systematic review aims to evaluate the efficacy of carbapenem ... ...

    Abstract Background: Carbapenem is recommended as one of the first-line regimens for ventilator-associated pneumonia (VAP), but no recent systematic review has fully investigated its efficacy. This systematic review aims to evaluate the efficacy of carbapenem compared with non-carbapenem for VAP treatment.
    Methods: We performed a systematic review and meta-analysis of studies comparing the efficacy and the safety between carbapenem and non-carbapenem with activity to Pseudomonas aeruginosa in the treatment for VAP. The main outcome was mortality, and the additional outcomes were the clinical cure of pneumonia, length of intensive care unit stay, recurrence, adverse effects, and the development of resistant bacteria. This study was conducted in accordance with the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines.
    Results: Of the initial 1,730 publications, 9 randomized control trials were enrolled. In the meta-analysis, no difference was observed between the carbapenem and non-carbapenem regimens in improving mortality (odds ratio, 0.83; 95 % confidence interval (CI) 0.67-1.02). While the carbapenem regimen was superior to the non-carbapenem regimen in studies reporting the resolution of pneumonia (odds ratio, 1.09; 95 % CI 1.01-1.17), the effectiveness of carbapenem treatment was not evident in studies assessing the other outcomes.
    Conclusions: Carbapenem might have no superiority in survival when treating VAP. Moreover, non-carbapenem antibiotics with activities to P. aeruginosa have a potential option to avoid inducing carbapenem-resistant pathogens.
    MeSH term(s) Humans ; Pneumonia, Ventilator-Associated/drug therapy ; Pneumonia, Ventilator-Associated/microbiology ; Carbapenems/therapeutic use ; Carbapenems/pharmacology ; Anti-Bacterial Agents/therapeutic use
    Chemical Substances Carbapenems ; Anti-Bacterial Agents
    Language English
    Publishing date 2024-01-07
    Publishing country Netherlands
    Document type Meta-Analysis ; Systematic Review ; Journal Article ; Review
    ZDB-ID 2660821-2
    ISSN 2212-5353 ; 2212-5345
    ISSN (online) 2212-5353
    ISSN 2212-5345
    DOI 10.1016/j.resinv.2023.12.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Lung Injury Induced by Crizotinib and Entrectinib in a Patient with ROS1-rearranged Non-small-cell Lung Cancer.

    Nishiyama, Yoshiki / Omori, Shota / Matsumoto, Hiroyuki / Komiya, Kosaku / Hiramatsu, Kazufumi

    Internal medicine (Tokyo, Japan)

    2023  Volume 62, Issue 23, Page(s) 3507–3510

    Abstract: We herein report the first case of c-ros oncogene 1 (ROS1)-rearranged advanced non-small-cell lung cancer (NSCLC) in which lung injury was induced by crizotinib and entrectinib. Crizotinib was administered as first-line chemotherapy in a woman in her ... ...

    Abstract We herein report the first case of c-ros oncogene 1 (ROS1)-rearranged advanced non-small-cell lung cancer (NSCLC) in which lung injury was induced by crizotinib and entrectinib. Crizotinib was administered as first-line chemotherapy in a woman in her early 70s with stage IV NSCLC showing ROS1 rearrangement. This resulted in the development of drug-induced organizing pneumonia, which was alleviated by discontinuing drug administration and giving corticosteroids. Following second-line chemotherapy with entrectinib, a similar lung injury was noted. In cases of crizotinib-induced lung injury, physicians must be alert for drug-induced lung injury in subsequent treatment with entrectinib.
    MeSH term(s) Female ; Humans ; Carcinoma, Non-Small-Cell Lung/drug therapy ; Carcinoma, Non-Small-Cell Lung/genetics ; Crizotinib/adverse effects ; Gene Rearrangement ; Lung Injury ; Lung Neoplasms/drug therapy ; Lung Neoplasms/genetics ; Oncogenes ; Protein Kinase Inhibitors/adverse effects ; Protein-Tyrosine Kinases/genetics ; Proto-Oncogene Proteins/genetics ; Aged
    Chemical Substances Crizotinib (53AH36668S) ; entrectinib (L5ORF0AN1I) ; Protein Kinase Inhibitors ; Protein-Tyrosine Kinases (EC 2.7.10.1) ; Proto-Oncogene Proteins ; ROS1 protein, human (EC 2.7.10.1)
    Language English
    Publishing date 2023-04-14
    Publishing country Japan
    Document type Case Reports ; Journal Article
    ZDB-ID 32371-8
    ISSN 1349-7235 ; 0021-5120 ; 0918-2918
    ISSN (online) 1349-7235
    ISSN 0021-5120 ; 0918-2918
    DOI 10.2169/internalmedicine.1255-22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 240: Show issues Location:
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  8. Article ; Online: Prevalence of antimicrobial resistant genes in Bacteroides spp. isolated in Oita Prefecture, Japan.

    Hashimoto, Takehiro / Hashinaga, Kazuhiko / Komiya, Kosaku / Hiramatsu, Kazufumi

    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy

    2022  Volume 29, Issue 3, Page(s) 284–288

    Abstract: Introduction: Bacteroides spp. are the most common anaerobic bacteria isolated from the human gastrointestinal tract. Several resistant genes are present in Bacteroides spp. However, most studies have focused on the prevalence of the cfiA gene in ... ...

    Abstract Introduction: Bacteroides spp. are the most common anaerobic bacteria isolated from the human gastrointestinal tract. Several resistant genes are present in Bacteroides spp. However, most studies have focused on the prevalence of the cfiA gene in Bacteroides fragilis alone. We assessed the susceptibility to antimicrobial agents and the prevalence of cepA, cfiA, cfxA, ermF, nim, and tetQ genes in Bacteroides strains isolated from clinical specimens in our hospital.
    Methods: We isolated 86 B. fragilis and 58 non-fragilis Bacteroides strains from human clinical specimens collected from January 2011 to November 2021. Resistance against piperacillin (PIPC), cefotaxime (CTX), cefepime (CFPM), meropenem (MEPM), clindamycin, and minocycline was determined.
    Results: The resistant rates of penicillins and cephalosporins in non-fragilis isolates were significantly higher than those in B. fragilis isolates. In B. fragilis isolates, the resistant rates of PIPC, CTX, and CFPM in cfxA-positive isolates were significantly higher than those in cfxA-negative isolates (71% vs. 16%, 77% vs. 19%, and 77% vs. 30%, respectively). Thirteen B. fragilis isolates harbored the cfiA gene, two of which were resistant to MEPM. Six of the 13 cfiA-positive B. fragilis isolates were heterogeneously resistant to MEPM.
    Conclusion: It is important to evaluate the use of MEPM as empirical therapy for Bacteroides spp. infections, considering the emergence of carbapenem resistance during treatment, existence of MEPM-resistant strains, and heterogeneous resistance.
    MeSH term(s) Humans ; Anti-Bacterial Agents/pharmacology ; Drug Resistance, Bacterial/genetics ; Prevalence ; Japan/epidemiology ; Microbial Sensitivity Tests ; Meropenem ; Bacteroides Infections/drug therapy ; Bacteroides Infections/epidemiology ; Bacteroides Infections/microbiology ; Bacteroides/genetics
    Chemical Substances Anti-Bacterial Agents ; Meropenem (FV9J3JU8B1)
    Language English
    Publishing date 2022-12-05
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1355399-9
    ISSN 1437-7780 ; 1341-321X
    ISSN (online) 1437-7780
    ISSN 1341-321X
    DOI 10.1016/j.jiac.2022.11.011
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  9. Article: The Efficacy of Penicillins with β-lactamase Inhibitor or Cefmetazole against Pneumonia in which ESBL-Producing Bacteria were Isolated from Sputum.

    Goto, Akihiko / Komiya, Kosaku / Hiramatsu, Kazufumi / Kadota, Jun-Ichi

    Infection & chemotherapy

    2021  Volume 53, Issue 3, Page(s) 562–564

    Language English
    Publishing date 2021-09-06
    Publishing country Korea (South)
    Document type Letter ; Comment
    ZDB-ID 2573798-3
    ISSN 2093-2340
    ISSN 2093-2340
    DOI 10.3947/ic.2021.0065
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  10. Article: Pneumocystis Pneumonia With Multiple Centrilobular Pulmonary Nodules and Lack of Ground-Glass Attenuation on High-Resolution Computed Tomography.

    Takaki, Ryuichiro / Komiya, Kosaku / Fujishima, Nobuhiro / Yamanaka, Marimu / Yokoyama, Atsushi / Hiramatsu, Kazufumi / Kadota, Jun-Ichi

    Cureus

    2023  Volume 15, Issue 2, Page(s) e35565

    Abstract: Pneumocystis ... ...

    Abstract Pneumocystis jirovecii
    Language English
    Publishing date 2023-02-28
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.35565
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