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  1. Article ; Online: Impact of needle-point bipolar ionization system in the reduction of bioaerosols in collective transport.

    Baselga, Marta / Alba, Juan J / Schuhmacher, Alberto J

    The Science of the total environment

    2022  Volume 855, Page(s) 158965

    MeSH term(s) Air Microbiology ; Aerosols
    Chemical Substances Aerosols
    Language English
    Publishing date 2022-09-23
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2022.158965
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 949: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  2. Article: Sturge-Weber Syndrome: A Review of Pathophysiology, Genetics, Clinical Features, and Current Management Approache.

    Sánchez-Espino, Luis Fernando / Ivars, Marta / Antoñanzas, Javier / Baselga, Eulalia

    The application of clinical genetics

    2023  Volume 16, Page(s) 63–81

    Abstract: Sturge-Weber syndrome (SWS) is a congenital, sporadic, and rare neurocutaneous disorder, characterized by the presence of a facial port-wine birthmark (PWB), glaucoma, and neurological manifestations including leptomeningeal angiomatosis and seizures. It ...

    Abstract Sturge-Weber syndrome (SWS) is a congenital, sporadic, and rare neurocutaneous disorder, characterized by the presence of a facial port-wine birthmark (PWB), glaucoma, and neurological manifestations including leptomeningeal angiomatosis and seizures. It is caused by a postzygotic, somatic, gain-of-function variant of the
    Language English
    Publishing date 2023-04-24
    Publishing country New Zealand
    Document type Journal Article ; Review
    ZDB-ID 2472464-6
    ISSN 1178-704X
    ISSN 1178-704X
    DOI 10.2147/TACG.S363685
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Impact of needle-point bipolar ionization system in the reduction of bioaerosols in collective transport

    Baselga, Marta / Alba, Juan J. / Schuhmacher, Alberto J.

    Science of the Total Environment. 2023 Jan., v. 855 p.158965-

    2023  

    Abstract: The transmission rate of SARS-CoV-2 is higher in collective transport than in other public environments. Transport companies require preventive strategies to mitigate airborne risk of contagion which not imply responsible use at the individual level. Air ...

    Abstract The transmission rate of SARS-CoV-2 is higher in collective transport than in other public environments. Transport companies require preventive strategies to mitigate airborne risk of contagion which not imply responsible use at the individual level. Air purification systems, such as UV-C or needle-tip bipolar ionization, are attractive alternatives. However, only a few studies addressing the validation of this technology against bioaerosols in actual operation conditions have been published so far. In this work, the efficiency of a bipolar ionization unit in the Zaragoza Tram has been evaluated. Against environmental bioaerosols, ionization (~25.7 · 10⁹ ions/m³, on average) reduced the concentration of colony-forming units (CFU) by ~46 % and ~69 % after 30 and 90 min. No clear benefits were obtained against microorganisms on inner tram surfaces (seats, grab bars, walls, and windows). ‘Pre-pandemic’ filtration equipment located in the HVAC based on a Coarse 45 %-type filter removed ~73 and ~ 92 % of aerial CFU by itself after 30 and 90 min. Microscopic visualization of the CFUs revealed that they were mostly >1 μm, much larger than the SARS-CoV-2 virion (~100 nm) and SARS-CoV-2-loaded bioaerosols (from 0.25 μm). Then, we studied the filter behavior under normalized laboratory methods. The filters efficiency against submicron particles was limited (between 5 and 12 % against 0.1 to 0.3 μm NaCl particles). Another ionization strategy was to generate aerosol agglomerates to enhance filtration performance, but the combined action of ionization and filtration did not improve substantially. The effect of these technologies was also characterized using the clean air delivery rate (CADR). Relative to untreated air (CADR = 0.299 m³/min), ionization and filtration reduce ambient CFUs (CADR = 5.153 and 9.261 m³/min, respectively; and CADR = 13.208 m³/min, combined) which implies that it has a substantial impact on indoor bioaerosols.
    Keywords Severe acute respiratory syndrome coronavirus 2 ; air ; bioaerosols ; environment ; equipment ; filtration ; ionization ; risk ; virion ; Collective transport ; Tramway ; Bipolar ionization ; Infectious diseases ; SARS-CoV-2
    Language English
    Dates of publication 2023-01
    Publishing place Elsevier B.V.
    Document type Article ; Online
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2022.158965
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 74/341: Show issues

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  4. Article ; Online: The Control of Metabolic CO

    Baselga, Marta / Alba, Juan J / Schuhmacher, Alberto J

    International journal of environmental research and public health

    2022  Volume 19, Issue 11

    Abstract: The global acceptance of the SARS-CoV-2 airborne transmission led to prevention measures based on quality control and air renewal. Among them, carbon dioxide ( ... ...

    Abstract The global acceptance of the SARS-CoV-2 airborne transmission led to prevention measures based on quality control and air renewal. Among them, carbon dioxide (CO
    MeSH term(s) Aerosols ; Air Pollution, Indoor/analysis ; COVID-19/prevention & control ; Carbon Dioxide ; Communicable Diseases ; Humans ; SARS-CoV-2 ; Ventilation
    Chemical Substances Aerosols ; Carbon Dioxide (142M471B3J)
    Language English
    Publishing date 2022-05-28
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph19116605
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  5. Article ; Online: Development and Validation of a Methodology to Measure Exhaled Carbon Dioxide (CO 2 ) and Control Indoor Air Renewal

    Marta Baselga / Juan J. Alba / Alberto J. Schuhmacher

    COVID, Vol 3, Iss 12, Pp 1797-

    2023  Volume 1817

    Abstract: The measurement of carbon dioxide (CO 2 ) has emerged as a cost-effective and straightforward technique for indirectly managing indoor air quality, aiding in the reduction of the potentially pathogen-laden aerosol concentrations to which we are exposed. ... ...

    Abstract The measurement of carbon dioxide (CO 2 ) has emerged as a cost-effective and straightforward technique for indirectly managing indoor air quality, aiding in the reduction of the potentially pathogen-laden aerosol concentrations to which we are exposed. Unfortunately, inadequate practices often limit the interpretation of CO 2 levels and neglect methodologies that ensure proper air renewal. This study presents a novel methodology for measuring and controlling indoor CO 2 levels in shared spaces, comprising four stages: analysis, diagnosis, correction protocols, and monitoring/control/surveillance (MCS). This methodology underwent validation in practical settings, including a cultural center (representing spaces with uniform activities) and 40 commercial spaces (with diverse activities) in Zaragoza, Spain. The results indicate the feasibility of swiftly implementing measures to enhance shared air renewal, with the immediate opening of doors and windows being the most direct solution. The proposed methodology is practical and has the potential to mitigate the risk of the aerosol transmission of respiratory diseases. Consequently, we anticipate that this work will contribute to establishing methodological foundations for CO 2 measurement as a valuable, standardized, and reliable tool.
    Keywords carbon dioxide ; CO 2 ; infectious diseases ; environmental engineering ; COVID-19 ; airborne transmission ; Specialties of internal medicine ; RC581-951
    Subject code 690
    Language English
    Publishing date 2023-12-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Phacomatosis pigmentokeratotica: Exploring extracutaneous comorbidities and topical therapy.

    Camiña-Conforto, Gemma / Ivars, Marta / Sarquella-Brugada, Georgia / Valera-Dávila, Carlos / Salvador, Héctor / Rovira, Carlota / Baselga, Eulalia

    Pediatric dermatology

    2024  

    Abstract: Phacomatosis pigmentokeratotica (PPK) is a RASopathy characterized by the presence of a sebaceous nevus and a papular speckled lentiginous nevus. This case report highlights the associated extracutaneous comorbidities, including life-threatening ... ...

    Abstract Phacomatosis pigmentokeratotica (PPK) is a RASopathy characterized by the presence of a sebaceous nevus and a papular speckled lentiginous nevus. This case report highlights the associated extracutaneous comorbidities, including life-threatening arrhythmia, and introduces topical rapamycin as a potential therapeutic avenue for sebaceous nevus in PPK patients.
    Language English
    Publishing date 2024-04-15
    Publishing country United States
    Document type Case Reports
    ZDB-ID 605539-4
    ISSN 1525-1470 ; 0736-8046
    ISSN (online) 1525-1470
    ISSN 0736-8046
    DOI 10.1111/pde.15632
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1882: Show issues Location:
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  7. Article ; Online: Spheresomes are the main extracellular vesicles in low-grade gliomas.

    Baselga, Marta / Iruzubieta, Pablo / Castiella, Tomás / Monzón, Marta / Monleón, Eva / Berga, Carmen / Schuhmacher, Alberto J / Junquera, Concepción

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 11180

    Abstract: Cancer progression and its impact on treatment response and prognosis is deeply regulated by tumour microenvironment (TME). Cancer cells are in constant communication and modulate TME through several mechanisms, including transfer of tumour-promoting ... ...

    Abstract Cancer progression and its impact on treatment response and prognosis is deeply regulated by tumour microenvironment (TME). Cancer cells are in constant communication and modulate TME through several mechanisms, including transfer of tumour-promoting cargos through extracellular vesicles (EVs) or oncogenic signal detection by primary cilia. Spheresomes are a specific EV that arise from rough endoplasmic reticulum-Golgi vesicles. They accumulate beneath cell membrane and are released to the extracellular medium through multivesicular spheres. This study describes spheresomes in low-grade gliomas using electron microscopy. We found that spheresomes are more frequent than exosomes in these tumours and can cross the blood-brain barrier. Moreover, the distinct biogenesis processes of these EVs result in unique cargo profiles, suggesting different functional roles. We also identified primary cilia in these tumours. These findings collectively contribute to our understanding of glioma progression and metastasis.
    MeSH term(s) Humans ; Glioma ; Extracellular Vesicles ; Exosomes ; Blood-Brain Barrier ; Cell Membrane ; Tumor Microenvironment
    Language English
    Publishing date 2023-07-10
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-38084-y
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  8. Article ; Online: Silbergraues Haar und neurologische Symptome bei einem 21 Monate alten Jungen.

    Rusiñol, Lluís / Baselga, Eulàlia / Garcia-Garcia, Ana / Armstrong, Judith / Prat, Carolina / Vicente, Asunción / Ivars, Marta

    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG

    2023  Volume 21, Issue 9, Page(s) 1043–1045

    Language German
    Publishing date 2023-08-08
    Publishing country Germany
    Document type Case Reports
    ZDB-ID 2093479-8
    ISSN 1610-0387 ; 1610-0379
    ISSN (online) 1610-0387
    ISSN 1610-0379
    DOI 10.1111/ddg.15109_g
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    Zs.A 6148: Show issues Location:
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  9. Article ; Online: PIK3CA-related congenital haemangioma.

    Luque-Luna, Mar / Ivars, Marta / Lavarino, Cinzia Emilia / Olaciregui, Nagore Gené / Zurriaga, Carlota Rovira / Martínez-Glez, Víctor / Baselga, Eulalia

    Journal of the European Academy of Dermatology and Venereology : JEADV

    2023  

    Language English
    Publishing date 2023-12-13
    Publishing country England
    Document type Letter
    ZDB-ID 1128828-0
    ISSN 1468-3083 ; 0926-9959
    ISSN (online) 1468-3083
    ISSN 0926-9959
    DOI 10.1111/jdv.19735
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    Zs.A 3492: Show issues Location:
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    Zs.MO 413: Show issues

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  10. Article ; Online: The Control of Metabolic CO 2 in Public Transport as a Strategy to Reduce the Transmission of Respiratory Infectious Diseases

    Marta Baselga / Juan J. Alba / Alberto J. Schuhmacher

    International Journal of Environmental Research and Public Health, Vol 19, Iss 6605, p

    2022  Volume 6605

    Abstract: The global acceptance of the SARS-CoV-2 airborne transmission led to prevention measures based on quality control and air renewal. Among them, carbon dioxide (CO 2 ) measurement has positioned itself as a cost-efficiency, reliable, and straightforward ... ...

    Abstract The global acceptance of the SARS-CoV-2 airborne transmission led to prevention measures based on quality control and air renewal. Among them, carbon dioxide (CO 2 ) measurement has positioned itself as a cost-efficiency, reliable, and straightforward method to assess indoor air renewal indirectly. Through the control of CO 2 , it is possible to implement and validate the effectiveness of prevention measures to reduce the risk of contagion of respiratory diseases by aerosols. Thanks to the method scalability, CO 2 measurement has become the gold standard for diagnosing air quality in shared spaces. Even though collective transport is considered one of the environments with the highest rate of COVID-19 propagation, little research has been done where the air inside vehicles is analyzed. This work explores the generation and accumulation of metabolic CO 2 in a tramway (Zaragoza, Spain) operation. Importantly, we propose to use the indicator ppm/person as a basis for comparing environments under different conditions. Our study concludes with an experimental evaluation of the benefit of modifying some parameters of the Heating–Ventilation–Air conditioning (HVAC) system. The study of the particle retention efficiency of the implemented filters shows a poor air cleaning performance that, at present, can be counteracted by opening windows. Seeking a post-pandemic scenario, it will be crucial to seek strategies to improve air quality in public transport to prevent the transmission of infectious diseases.
    Keywords airborne ; CO 2 ; collective transport ; SARS-CoV-2 ; tramway ; filtration ; Medicine ; R
    Subject code 380
    Language English
    Publishing date 2022-05-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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