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  1. Article ; Online: The Coronavirus crisis in B2B settings: Crisis uniqueness and managerial implications based on social exchange theory

    Cortez, Roberto Mora / Johnston, Wesley J.

    Abstract: Abstract The current Coronavirus crisis is having disastrous effects for most B2B firms around the world. The decline in sales provokes intra-organizational and inter-organizational tension, requiring a new approach for managing firms' business ... ...

    Abstract Abstract The current Coronavirus crisis is having disastrous effects for most B2B firms around the world. The decline in sales provokes intra-organizational and inter-organizational tension, requiring a new approach for managing firms' business operations. Particularly, the direct threat to human beings places the attention of managers on the individual. This study investigates the main differences between prior “traditional” financial-based crises and the practices that managers can adopt to navigate and survive the Coronavirus crisis from a social exchange theory (SET) view. The authors identify eight crisis-comparative dimensions to consider to successfully prevail: (1) formation, (2) focus, (3) temporality, (4) government jurisdiction, (5) preparedness, (6) normality, (7) business, and (8) operational deployment. In addition, the study results propose four intertwined areas to classify the managerial practices: (1) digital transformation, (2) decision-making processes, (3) leadership, and (4) emotions and stress.
    Keywords covid19
    Publisher Elsevier; PMC
    Document type Article ; Online
    DOI 10.1016/j.indmarman.2020.05.004
    Database COVID19

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  2. Article: The future of B2B marketing theory

    Mora Cortez, Roberto / Johnston, Wesley J

    Industrial marketing management : the international journal for industrial and high-tech firms Vol. 66 , p. 90-102

    a historical and prospective analysis

    2017  Volume 66, Page(s) 90–102

    Author's details Roberto Mora Cortez, Wesley J. Johnston
    Keywords B2B marketing ; Historical development ; Delphi method ; Coding ; Theory construction ; Future challenges
    Language English
    Publisher Elsevier
    Publishing place New York, NY [u.a.]
    Document type Article
    ZDB-ID 120124-4 ; 2012747-9
    ISSN 1873-2062 ; 0019-8501
    ISSN (online) 1873-2062
    ISSN 0019-8501
    Database ECONomics Information System

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  3. Article: A new model for measuring salesperson lifetime value

    Farías, Pablo / Cortez, Roberto Mora / Torres, Eduardo

    The journal of business & industrial marketing Vol. 32, No. 2 , p. 274-281

    2017  Volume 32, Issue 2, Page(s) 274–281

    Author's details Pablo Farías, Eduardo Torres and Roberto Mora Cortez
    Keywords Financial reporting ; Intangible assets ; Salesforce equity ; Salesperson lifetime value ; Salesperson valuation ; Valuation approaches
    Language English
    Publisher Emerald Publishing Limited
    Publishing place Bingley
    Document type Article
    ZDB-ID 649550-3 ; 2019934-X
    ISSN 0885-8624
    ISSN 0885-8624
    Database ECONomics Information System

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  4. Article: Machine learning combining multi-omics data and network algorithms identifies adrenocortical carcinoma prognostic biomarkers.

    Martin-Hernandez, Roberto / Espeso-Gil, Sergio / Domingo, Clara / Latorre, Pablo / Hervas, Sergi / Hernandez Mora, Jose Ramon / Kotelnikova, Ekaterina

    Frontiers in molecular biosciences

    2023  Volume 10, Page(s) 1258902

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2023-11-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2814330-9
    ISSN 2296-889X
    ISSN 2296-889X
    DOI 10.3389/fmolb.2023.1258902
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: High resolution continuous arterial spin labeling of human cerebral perfusion using a separate neck tagging RF coil.

    Mora Álvarez, María Guadalupe / Stobbe, Robert Wayne / Beaulieu, Christian

    PloS one

    2019  Volume 14, Issue 4, Page(s) e0215998

    Abstract: ... implementation yielded perfusion images with improved cortex depiction and increased cortical CBF measurements ...

    Abstract For standard clinical applications, ASL images are typically acquired with 4-8 mm thick slices and 3-4 mm in-plane resolution. However, in this paper we demonstrate that high-resolution continuous arterial spin labeling (CASL) perfusion images can be acquired in a clinically relevant scan time using current MRI technology. CASL was implemented with a separate neck coil for labeling the arterial blood on a 4.7T MRI using standard axial 2D GE-EPI. Typical-resolution to high-resolution (voxels of 95, 60, 45, 27, or 7 mm3) images were compared for qualitative and quantitative cerebral blood flow analysis (CBF) in nine healthy volunteers (ages: 24-32 years). The highest resolution (1.5x1.5x3 = 7 mm3) CASL implementation yielded perfusion images with improved cortex depiction and increased cortical CBF measurements (53 ± 8 ml/100g/min), consistent with reduced partial volume averaging. The 7 mm3 voxel images were acquired with 6 cm brain coverage in a clinically relevant scan of 6 minutes. Improved spatial resolution facilitates CBF measurement with reduced partial volume averaging and may be valuable for the detection of perfusion deficits in small lesions and perfusion measurement in small brain regions.
    MeSH term(s) Adult ; Arteries/diagnostic imaging ; Arteries/physiology ; Cerebrovascular Circulation/physiology ; Female ; Gray Matter/diagnostic imaging ; Humans ; Image Processing, Computer-Assisted ; Magnetic Resonance Imaging/instrumentation ; Male ; Neck/diagnostic imaging ; Perfusion ; Spin Labels ; White Matter/diagnostic imaging ; Young Adult
    Chemical Substances Spin Labels
    Language English
    Publishing date 2019-04-25
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0215998
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Machine learning combining multi-omics data and network algorithms identifies adrenocortical carcinoma prognostic biomarkers

    Roberto Martin-Hernandez / Sergio Espeso-Gil / Clara Domingo / Pablo Latorre / Sergi Hervas / Jose Ramon Hernandez Mora / Ekaterina Kotelnikova

    Frontiers in Molecular Biosciences, Vol

    2023  Volume 10

    Abstract: Background: Rare endocrine cancers such as Adrenocortical Carcinoma (ACC) present a serious ... Adrenocortical Carcinoma cohort). A highly correlated multi-omics signature discriminating groups of samples was identified ...

    Abstract Background: Rare endocrine cancers such as Adrenocortical Carcinoma (ACC) present a serious diagnostic and prognostication challenge. The knowledge about ACC pathogenesis is incomplete, and patients have limited therapeutic options. Identification of molecular drivers and effective biomarkers is required for timely diagnosis of the disease and stratify patients to offer the most beneficial treatments. In this study we demonstrate how machine learning methods integrating multi-omics data, in combination with system biology tools, can contribute to the identification of new prognostic biomarkers for ACC.Methods: ACC gene expression and DNA methylation datasets were downloaded from the Xena Browser (GDC TCGA Adrenocortical Carcinoma cohort). A highly correlated multi-omics signature discriminating groups of samples was identified with the data integration analysis for biomarker discovery using latent components (DIABLO) method. Additional regulators of the identified signature were discovered using Clarivate CBDD (Computational Biology for Drug Discovery) network propagation and hidden nodes algorithms on a curated network of molecular interactions (MetaBase™). The discriminative power of the multi-omics signature and their regulators was delineated by training a random forest classifier using 55 samples, by employing a 10-fold cross validation with five iterations. The prognostic value of the identified biomarkers was further assessed on an external ACC dataset obtained from GEO (GSE49280) using the Kaplan-Meier estimator method. An optimal prognostic signature was finally derived using the stepwise Akaike Information Criterion (AIC) that allowed categorization of samples into high and low-risk groups.Results: A multi-omics signature including genes, micro RNA's and methylation sites was generated. Systems biology tools identified additional genes regulating the features included in the multi-omics signature. RNA-seq, miRNA-seq and DNA methylation sets of features revealed a high power to classify patients from ...
    Keywords ACC ; multi-omics ; machine learning ; systems biology ; survival analysis ; prognostic biomarkers ; Biology (General) ; QH301-705.5
    Subject code 006
    Language English
    Publishing date 2023-11-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Efectos de la suplementación oral y ejercicios de resistencia durante la sesión de hemodiálisis en pacientes del Hospital Infantil Dr. Robert Reid Cabral, período abril-junio 2019

    Willna De la Rosa Brito / Ankia Mora / Manuel Colomé Hidalgo / Yun Zyong Kim

    Ciencia y Salud, Vol 6, Iss

    2022  Volume 1

    Abstract: Se realizó un estudio tipo descriptivo, prospectivo, de corte transversal, con el objetivo ... Hospital Infantil Dr. Robert Reid Cabral abril-junio 2019. La población estuvo conformada por 60 pacientes ...

    Abstract Se realizó un estudio tipo descriptivo, prospectivo, de corte transversal, con el objetivo de establecer los efectos de la suplementación oral y ejercicios de resistencia en pacientes de hemodiálisis Hospital Infantil Dr. Robert Reid Cabral abril-junio 2019. La población estuvo conformada por 60 pacientes con Enfermedad Renal Crónica perteneciente al servicio de diálisis, mientras que la muestra estuvo constituida por 17 pacientes. Finalizamos el proyecto con 11 pacientes, en vista de que en el periodo descrito se trasladaron 3 a diálisis peritoneal, 1 fue referido a adulto, 1 fallecido, 1 abandonó el estudio. La técnica utilizada para el levantamiento de la información fue un cuestionario de recolección de datos, procesados con el programa estadístico SPSS, utilizándose la prueba de Wilcoxon, donde el contraste de hipótesis es comparado con el valor p = 0.05, un nivel de confianza del 95 %. Los hallazgos más relevantes mostraron que la edad más frecuente fue 17 años, El sexo más frecuente el masculino; un promedio del 63.6 % tomaron del 90-100 % del suplemento indicado. El promedio de ejercicios realizado fue de 20-30 minutos. Los signos y síntomas frecuentes como efecto secundario a la realización de ejercicios se presentaron en 3 pacientes: dolor muscular; y vómito y dolor abdominal para la ingesta del suplemento. El peso tuvo un rango promedio de 3-5 % ganado. Para el índice de masa corporal el porcentaje ganado fue 1-6 %. La evolución de la masa muscular tuvo un promedio ganado de 11-15 %. En la evolución de la masa grasa 36 % perdieron entre 6-14 % de grasa. Tanto la hemoglobina como el hematocrito aumentaron en el 100 % de los pacientes. Los niveles de urea, proteínas y albúmina no evidenciaron diferencias significativas. En conclusión, demostramos en este estudio que administrando suplementación oral intradialítica, aunada a ejercicios físicos, se mejora la composición corporal de los pacientes en hemodiálisis.
    Keywords suplementación oral ; ejercicios de resistencia ; hemodiálisis ; pediatría ; Medicine (General) ; R5-920 ; Public aspects of medicine ; RA1-1270
    Language Spanish
    Publishing date 2022-02-01T00:00:00Z
    Publisher Instituto Tecnológico de Santo Domingo (INTEC)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Prenatal and childhood exposure to organophosphate pesticides and functional brain imaging in young adults.

    Sagiv, Sharon K / Baker, Joseph M / Rauch, Stephen / Gao, Yuanyuan / Gunier, Robert B / Mora, Ana M / Kogut, Katherine / Bradman, Asa / Eskenazi, Brenda / Reiss, Allan L

    Environmental research

    2023  Volume 242, Page(s) 117756

    Abstract: ... associated with altered cortical activation using functional near infrared spectroscopy (fNIRS) in a small ... of prenatal and childhood urinary dialkylphosphates (DAPs), non-specific OP metabolites, with cortical ... prefrontal cortex of the right hemisphere during the letter retrieval working memory task (β = -3.10; 95% CI: -6.43 ...

    Abstract Background: Early life exposure to organophosphate (OP) pesticides has been linked with poorer neurodevelopment from infancy to adolescence. In our Center for the Health Assessment of Mothers and Children of Salinas (CHAMACOS) birth cohort, we previously reported that residential proximity to OP use during pregnancy was associated with altered cortical activation using functional near infrared spectroscopy (fNIRS) in a small subset (n = 95) of participants at age 16 years.
    Methods: We administered fNIRS to 291 CHAMACOS young adults at the 18-year visit. Using covariate-adjusted regression models, we estimated associations of prenatal and childhood urinary dialkylphosphates (DAPs), non-specific OP metabolites, with cortical activation in the frontal, temporal, and parietal regions of the brain during tasks of executive function and semantic language.
    Results: There were some suggestive associations for prenatal DAPs with altered activation patterns in both the inferior frontal and inferior parietal lobes of the left hemisphere during a task of cognitive flexibility (β per ten-fold increase in DAPs = 3.37; 95% CI: -0.02, 6.77 and β = 3.43; 95% CI: 0.64, 6.22, respectively) and the inferior and superior frontal pole/dorsolateral prefrontal cortex of the right hemisphere during the letter retrieval working memory task (β = -3.10; 95% CI: -6.43, 0.22 and β = -3.67; 95% CI: -7.94, 0.59, respectively). We did not observe alterations in cortical activation with prenatal DAPs during a semantic language task or with childhood DAPs during any task.
    Discussion: We observed associations of prenatal OP concentrations with mild alterations in cortical activation during tasks of executive function. Associations with childhood exposure were null. This is reasonably consistent with studies of prenatal OPs and neuropsychological measures of attention and executive function found in CHAMACOS and other birth cohorts.
    MeSH term(s) Adolescent ; Child ; Female ; Humans ; Pregnancy ; Brain/diagnostic imaging ; Functional Neuroimaging ; Insecticides ; Maternal Exposure/adverse effects ; Organophosphates/toxicity ; Organophosphates/urine ; Organophosphorus Compounds/toxicity ; Pesticides/toxicity ; Pesticides/urine ; Prenatal Exposure Delayed Effects/chemically induced
    Chemical Substances Insecticides ; Organophosphates ; Organophosphorus Compounds ; Pesticides
    Language English
    Publishing date 2023-11-26
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 205699-9
    ISSN 1096-0953 ; 0013-9351
    ISSN (online) 1096-0953
    ISSN 0013-9351
    DOI 10.1016/j.envres.2023.117756
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  9. Article ; Online: Distributional extension for a dry forest species, Mesoscincus managuae (Dunn, 1933) (Squamata, Scincidae), on the Subhumid Caribbean versant of Honduras

    Mario Roberto Espinal / José Manuel Mora

    Check List, Vol 15, Iss 2, Pp 269-

    2019  Volume 273

    Abstract: ... of Cortés. This is a subhumid habitat similar to others in the Mesoamerican region which have comparable ...

    Abstract Mesoscincus managuae (Dunn, 1933) (Squamata, Scincidae) is a typical dry-forest species found along the Pacific versant of Central America from Guatemala to northwestern Costa Rica. Here, we report the occurrence of this species on the Caribbean versant of Honduras, specifically on the Sula Plain, Deparment of Cortés. This is a subhumid habitat similar to others in the Mesoamerican region which have comparable herpetofauna assemblages and where M. managuae has already been recorded.
    Keywords Herpetofauna assemblages ; Mesoamerican Hotspot ; Sa ; Biology (General) ; QH301-705.5
    Language English
    Publishing date 2019-03-01T00:00:00Z
    Publisher Pensoft Publishers
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article: Distributional extension for a dry forest species, Mesoscincus managuae (Dunn, 1933) (Squamata, Scincidae), on the Subhumid Caribbean versant of Honduras

    Espinal, Mario Roberto / Mora, José Manuel

    Check list. 2019 Mar. 15, v. 15, no. 2

    2019  

    Abstract: ... of Cortés. This is a subhumid habitat similar to others in the Mesoamerican region which have comparable ...

    Abstract Mesoscincus managuae (Dunn, 1933) (Squamata, Scincidae) is a typical dry-forest species found along the Pacific versant of Central America from Guatemala to northwestern Costa Rica. Here, we report the occurrence of this species on the Caribbean versant of Honduras, specifically on the Sula Plain, Deparment of Cortés. This is a subhumid habitat similar to others in the Mesoamerican region which have comparable herpetofauna assemblages and where M. managuae has already been recorded.
    Keywords Scincidae ; Sula ; dry forests ; habitats ; herpetofauna ; subhumid zones ; Caribbean ; Costa Rica ; Guatemala ; Honduras
    Language English
    Dates of publication 2019-0315
    Size p. 269-273.
    Publishing place Pensoft Publishers
    Document type Article
    ZDB-ID 2252867-2
    ISSN 1809-127X
    ISSN 1809-127X
    DOI 10.15560/15.2.269
    Database NAL-Catalogue (AGRICOLA)

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