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  1. Article ; Online: Iron Oxide (Magnetite)-Based Nanobiomaterial with Medical Applications-Environmental Hazard Assessment Using Terrestrial Model Species.

    Gomes, Susana I L / Scott-Fordsmand, Janeck J / Amorim, Mónica J B

    Journal of xenobiotics

    2024  Volume 14, Issue 1, Page(s) 285–294

    Abstract: Nanobiomaterials (NBMs) have tremendous potential applications including in cancer diagnosis and treatment. However, the health and environmental effects of NBMs must be thoroughly assessed to ensure safety. ... ...

    Abstract Nanobiomaterials (NBMs) have tremendous potential applications including in cancer diagnosis and treatment. However, the health and environmental effects of NBMs must be thoroughly assessed to ensure safety. Fe
    Language English
    Publishing date 2024-02-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2649720-7
    ISSN 2039-4713 ; 2039-4713
    ISSN (online) 2039-4713
    ISSN 2039-4713
    DOI 10.3390/jox14010017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Using Machine Learning to make nanomaterials sustainable.

    Scott-Fordsmand, Janeck J / Amorim, Mónica J B

    The Science of the total environment

    2022  Volume 859, Issue Pt 2, Page(s) 160303

    Abstract: Sustainable development is a key challenge for contemporary human societies; failure to achieve sustainability could threaten human survival. In this review article, we illustrate how Machine Learning (ML) could support more sustainable development, ... ...

    Abstract Sustainable development is a key challenge for contemporary human societies; failure to achieve sustainability could threaten human survival. In this review article, we illustrate how Machine Learning (ML) could support more sustainable development, covering the basics of data gathering through each step of the Environmental Risk Assessment (ERA). The literature provides several examples showing how ML can be employed in most steps of a typical ERA.A key observation is that there are currently no clear guidance for using such autonomous technologies in ERAs or which standards/checks are required. Steering thus seems to be the most important task for supporting the use of ML in the ERA of nano- and smart-materials. Resources should be devoted to developing a strategy for implementing ML in ERA with a strong emphasis on data foundations, methodologies, and the related sensitivities/uncertainties. We should recognise historical errors and biases (e.g., in data) to avoid embedding them during ML programming.
    Language English
    Publishing date 2022-11-18
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2022.160303
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Corrigendum to "Environmental hazards of WELGRO® Cu+Zn: A nano-enabled fertilizer" [Environ. Pollut. (2023) 336 122469].

    Gomes, Susana I L / Chidiamassamba, Sekerani B / Trindade, Tito / Scott-Fordsmand, Janeck J / Amorim, Mónica J B

    Environmental pollution (Barking, Essex : 1987)

    2023  Volume 343, Page(s) 123176

    Language English
    Publishing date 2023-12-17
    Publishing country England
    Document type Published Erratum
    ZDB-ID 280652-6
    ISSN 1873-6424 ; 0013-9327 ; 0269-7491
    ISSN (online) 1873-6424
    ISSN 0013-9327 ; 0269-7491
    DOI 10.1016/j.envpol.2023.123176
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: The Curious Case of Earthworms and COVID-19.

    Scott-Fordsmand, Janeck J / Amorim, Monica J B

    Biology

    2021  Volume 10, Issue 10

    Abstract: Earthworms have been used for centuries in traditional medicine and are used globally as an ecotoxicological standard test species. Studies of the ... ...

    Abstract Earthworms have been used for centuries in traditional medicine and are used globally as an ecotoxicological standard test species. Studies of the earthworm
    Language English
    Publishing date 2021-10-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2661517-4
    ISSN 2079-7737
    ISSN 2079-7737
    DOI 10.3390/biology10101043
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Safe and sustainable by design Ag nanomaterials: A case study to evaluate the bio-reactivity in the environment using a soil model invertebrate.

    Gomes, Susana I L / Zanoni, Ilaria / Blosi, Magda / Costa, Anna L / Hristozov, Danail / Scott-Fordsmand, Janeck J / Amorim, Mónica J B

    The Science of the total environment

    2024  Volume 927, Page(s) 171860

    Abstract: Safe-and-sustainable-by-design (SSbD) nanomaterials (NMs) or NM-containing products are a priority. Silver (Ag) NMs have a vast array of applications, including biomedical and other products, even as nanopesticides. Thus, their release to the environment ...

    Abstract Safe-and-sustainable-by-design (SSbD) nanomaterials (NMs) or NM-containing products are a priority. Silver (Ag) NMs have a vast array of applications, including biomedical and other products, even as nanopesticides. Thus, their release to the environment is expected to increase. The aim of the present study was to assess the ecotoxicity of the SSbD Ag NM to the soil model species Enchytraeus crypticus (Oligochaeta). The Ag NM tested consists in a SSbD Ag with biomedical applications, a hydroxyethyl cellulose (HEC) coated Ag NMs (AgHEC) and its toxicity was compared to the naked Ag NMs (Ag-Sigma), an Ag-based biomedical product (PLLA-Ag: Poly l-Lactide microfibers doped with Ag), and AgNO
    MeSH term(s) Silver/toxicity ; Animals ; Soil Pollutants/analysis ; Oligochaeta/drug effects ; Soil/chemistry ; Metal Nanoparticles/toxicity ; Nanostructures/toxicity ; Invertebrates/drug effects
    Chemical Substances Silver (3M4G523W1G) ; Soil Pollutants ; Soil
    Language English
    Publishing date 2024-03-20
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2024.171860
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Environmental hazards of nanopesticides to non-target soil species - commercial nanoformulation versus its active substance (Karate Zeon® and lambda-cyhalothrin).

    Gomes, Susana I L / Chidiamassamba, Sekerani B / Scott-Fordsmand, Janeck J / Amorim, Mónica J B

    The Science of the total environment

    2023  Volume 891, Page(s) 164664

    Abstract: Nanopesticides (Npes) carry the potential of increased efficacy while reducing application rates, hence increasing agricultural productivity in a more sustainable way. However, given its novelty, the environmental risk assessment of these advanced ... ...

    Abstract Nanopesticides (Npes) carry the potential of increased efficacy while reducing application rates, hence increasing agricultural productivity in a more sustainable way. However, given its novelty, the environmental risk assessment of these advanced materials is mostly absent. In the present study we investigated the ecotoxicity of a commercial insecticide, with reported nanofeatures, Karate Zeon®, and compared it to its active substance lambda-cyhalothrin. It is hypothesised that the use of the nanopesticide Karate Zeon® poses lower risk to enchytraeids than its active substance. The standard non-target soil invertebrate Enchytraeus crypticus was used, and exposure was done in LUFA 2.2 soil in 4 tests (endpoints: days): avoidance test [avoidance behaviour: 2 days], OECD standard reproduction test [survival, reproduction plus adults' size: 28 days] and its extension [total number organisms: 56 days], and Full Life Cycle (FLC) test [hatching and juveniles' size: 13 days; survival, reproduction and adults' size: 46 days]. Results showed that enchytraeids did not avoid Karate Zeon® nor its active substance lambda-cyhalothrin, which could be due to neurotoxicity. There was no indication of increased toxicity with prolonged exposure (46, 56d) compared to the standard (28d) for neither of the materials, being overall equally toxic in terms of hatching, survival, and reproduction. The FLCt results indicated that the juvenile stage was the most sensitive, resulting in higher toxicity for the adult animals when exposed from the cocoon stage. Although toxicity was similar between Karate Zeon and lambda-cyhalothrin, different patterns of uptake and elimination cannot be excluded. The benefits of using Karate Zeon will rely on reduced application rates.
    MeSH term(s) Animals ; Soil ; Pyrethrins/toxicity ; Life Cycle Stages ; Reproduction ; Soil Pollutants/toxicity ; Oligochaeta
    Chemical Substances cyhalothrin (V0V73PEB8M) ; Soil ; Pyrethrins ; Soil Pollutants
    Language English
    Publishing date 2023-06-05
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2023.164664
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Environmental hazards of WELGRO® Cu+Zn: A nano-enabled fertilizer.

    Gomes, Susana I L / Chidiamassamba, Sekerani B / Trindade, Tito / Scott-Fordsmand, Janeck J / Amorim, Mónica J B

    Environmental pollution (Barking, Essex : 1987)

    2023  Volume 336, Page(s) 122469

    Abstract: Nanoagrochemicals have the potential to revolutionize agriculture towards a precision farming system, able to reduce application rates and consequently their environmental footprint, while keeping efficacy. Several nanoagrochemicals (including ... ...

    Abstract Nanoagrochemicals have the potential to revolutionize agriculture towards a precision farming system, able to reduce application rates and consequently their environmental footprint, while keeping efficacy. Several nanoagrochemicals (including nanopesticides (Npes) and nanofertilizers (Nfer)) are already commercialized but the environmental risk assessment of these advanced materials is often lacking. In the present study, we studied the commercial fertilizer WELGRO® Cu + Zn and assessed its ecotoxicity to the soil invertebrate species Enchytraeus crypticus (Oligochaeta), further comparing it to its individual active substances CuO and ZnO. To get a comprehensive picture of possible effects, we used four types of highly relevant tests in LUFA 2.2 soil: 1) avoidance behaviour (2 days), 2) reproduction (OECD standard, 28 d), 3) its extension (56 d), and 4) the full life cycle (FLC) (46 d) - this high level of hazard screening allows for increased interpretation. The results confirmed the nano-features of WELGRO® and a higher toxicity than the mixture of the individual components CuO + ZnO. E. crypticus avoided the soil spiked with WELGRO® and CuO + ZnO, this being the most sensitive endpoint - avoidance behaviour. Both WELGRO® and the active substances were little to non-toxic based on the OECD standard test. However, the toxicity dramatically increased in the tests focussing on longer-term sustainability measures, i.e., 56 days, ca. 170 for WELGRO®. This seems related to the nano-features of WELGRO®, e.g., slow release of ions from the nanoparticles throughout time. The FLCt results showed WELGRO® affected hatching and juveniles' survival, being these the most sensitive life stages. Hence, under actual real world field usage scenarios, i.e., based on the recommended application rates, nanoenabled WELGRO® can affect oligochaete populations like enchytraeids, both via the immediate avoidance behaviour and also via prolonged exposure periods.
    MeSH term(s) Animals ; Fertilizers/toxicity ; Zinc Oxide/pharmacology ; Soil Pollutants/analysis ; Reproduction ; Soil/chemistry ; Zinc/pharmacology ; Oligochaeta
    Chemical Substances Fertilizers ; Zinc Oxide (SOI2LOH54Z) ; Soil Pollutants ; Soil ; Zinc (J41CSQ7QDS)
    Language English
    Publishing date 2023-08-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 280652-6
    ISSN 1873-6424 ; 0013-9327 ; 0269-7491
    ISSN (online) 1873-6424
    ISSN 0013-9327 ; 0269-7491
    DOI 10.1016/j.envpol.2023.122469
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Multigenerational exposure of Ag materials (nano and salt) in soil - environmental hazards in

    Santos, Fátima C F / Verweij, Rudo A / Soares, Amadeu M V M / Scott-Fordsmand, Janeck J / van Gestel, Cornelis A M / Amorim, Mónica J B

    Nanoscale advances

    2023  Volume 6, Issue 3, Page(s) 826–831

    Abstract: Because of its properties, silver is among the most used metals both as salt and as nanomaterials (NMs), hence reaching the environment. Multigenerational (MG) exposure testing is scarce, and especially so for NMs and soil invertebrates. In this study ... ...

    Abstract Because of its properties, silver is among the most used metals both as salt and as nanomaterials (NMs), hence reaching the environment. Multigenerational (MG) exposure testing is scarce, and especially so for NMs and soil invertebrates. In this study the MG effects of Ag NMs (Ag NM300K) and Ag salt (AgNO
    Language English
    Publishing date 2023-11-22
    Publishing country England
    Document type Journal Article
    ISSN 2516-0230
    ISSN (online) 2516-0230
    DOI 10.1039/d3na00487b
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: TiO

    Gomes, Susana I L / Roca, Carlos P / Pokhrel, Suman / Mädler, Lutz / Scott-Fordsmand, Janeck J / Amorim, Mónica J B

    NanoImpact

    2023  Volume 30, Page(s) 100458

    Abstract: The hazards of nanomaterials/nanoparticles (NMs/NPs) are mostly assessed using individual NMs, and a more systematic approach, using many NMs, is needed to evaluate its risks in the environment. Libraries of NMs, with a range of identified different but ... ...

    Abstract The hazards of nanomaterials/nanoparticles (NMs/NPs) are mostly assessed using individual NMs, and a more systematic approach, using many NMs, is needed to evaluate its risks in the environment. Libraries of NMs, with a range of identified different but related characters/descriptors allow the comparison of effects across many NMs. The effects of a custom designed Fe-doped TiO
    MeSH term(s) Transcriptome ; Metal Nanoparticles/adverse effects ; Gene Expression Profiling ; Titanium/toxicity
    Chemical Substances titanium dioxide (15FIX9V2JP) ; Titanium (D1JT611TNE)
    Language English
    Publishing date 2023-02-27
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2452-0748
    ISSN (online) 2452-0748
    DOI 10.1016/j.impact.2023.100458
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Avoidance Behaviour of Six Collembolan Species Shows Species-Specific Sensitivity-Impact of Ag NM300K.

    Kovačević, Marija / Amorim, Mónica J B / Hackenberger, Branimir K / Scott-Fordsmand, Janeck J

    Nanomaterials (Basel, Switzerland)

    2022  Volume 12, Issue 19

    Abstract: Although standard testing guidelines use a species as a representative surrogate, species-specific sensitivity is well-known. The aim of this study was to investigate the species-specific difference in avoidance behaviour among Collembola species exposed ...

    Abstract Although standard testing guidelines use a species as a representative surrogate, species-specific sensitivity is well-known. The aim of this study was to investigate the species-specific difference in avoidance behaviour among Collembola species exposed to silver (Ag) nanomaterials (NM) (Ag NM300K). The avoidance test was performed with
    Language English
    Publishing date 2022-09-21
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662255-5
    ISSN 2079-4991
    ISSN 2079-4991
    DOI 10.3390/nano12193276
    Database MEDical Literature Analysis and Retrieval System OnLINE

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