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  1. Article ; Online: Can Two Coffees a Day Keep the Heart Doctor Away?

    Vest, Amanda R

    Circulation. Heart failure

    2021  Volume 14, Issue 2, Page(s) e008297

    MeSH term(s) Coffee ; Heart Failure ; Humans
    Chemical Substances Coffee
    Language English
    Publishing date 2021-02-09
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2429459-7
    ISSN 1941-3297 ; 1941-3289
    ISSN (online) 1941-3297
    ISSN 1941-3289
    DOI 10.1161/CIRCHEARTFAILURE.121.008297
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6745: Show issues Location:
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  2. Article ; Online: Detecting and managing cardiac allograft vasculopathy within the transition from pediatric to adult heart transplantation care: Lighting the pathway ahead.

    Vest, Amanda R / Daly, Kevin P

    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation

    2023  Volume 43, Issue 2, Page(s) 238–240

    MeSH term(s) Adult ; Humans ; Child ; Lighting ; Heart Transplantation ; Coronary Disease/diagnosis ; Heart Diseases ; Allografts
    Language English
    Publishing date 2023-10-13
    Publishing country United States
    Document type Editorial
    ZDB-ID 1062522-7
    ISSN 1557-3117 ; 1053-2498
    ISSN (online) 1557-3117
    ISSN 1053-2498
    DOI 10.1016/j.healun.2023.10.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2056: Show issues Location:
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  3. Article ; Online: Finding the Words and Data to Discuss Donor Characteristics With Heart Transplant Recipients and Families: Reconsidering Risk.

    Vest, Amanda R / Blume, Elizabeth D

    JAMA cardiology

    2022  Volume 7, Issue 11, Page(s) 1127–1128

    MeSH term(s) Humans ; Tissue Donors ; Heart Transplantation
    Language English
    Publishing date 2022-10-06
    Publishing country United States
    Document type Journal Article
    ISSN 2380-6591
    ISSN (online) 2380-6591
    DOI 10.1001/jamacardio.2022.3077
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Does an Ischemic "STICH in Time Save Nine" for Patients Newly Diagnosed With Heart Failure?

    Vest, Amanda R / Udelson, James

    JACC. Heart failure

    2022  Volume 10, Issue 11, Page(s) 816–818

    MeSH term(s) Humans ; Heart Failure/diagnosis ; Heart Failure/therapy ; Ventricular Dysfunction, Left ; Coronary Artery Bypass ; Myocardial Ischemia
    Language English
    Publishing date 2022-10-12
    Publishing country United States
    Document type Editorial
    ZDB-ID 2705621-1
    ISSN 2213-1787 ; 2213-1779
    ISSN (online) 2213-1787
    ISSN 2213-1779
    DOI 10.1016/j.jchf.2022.08.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: How Do I Optimize Heart Failure Medications for Patients with Hypotension or Chronic Kidney Disease?

    Gilstrap, Lauren G / Vest, Amanda R

    NEJM evidence

    2022  Volume 1, Issue 10, Page(s) EVIDccon2200084

    Abstract: HF Medications for Hypotension or CKDThe cornerstone of treatment for HF with reduced ejection fraction is GDMT; however, safely delivering maximal therapy is often hampered by low blood pressure, labile renal function, or both. Reviewing the physiologic ...

    Abstract HF Medications for Hypotension or CKDThe cornerstone of treatment for HF with reduced ejection fraction is GDMT; however, safely delivering maximal therapy is often hampered by low blood pressure, labile renal function, or both. Reviewing the physiologic basis of GDMT and exploring each drug's mechanism of action and unique properties can enable careful initiation and titration of therapy, even in patients with hypotension or CKD.
    MeSH term(s) Humans ; Stroke Volume/physiology ; Heart Failure/drug therapy ; Renal Insufficiency, Chronic/drug therapy ; Hypotension
    Language English
    Publishing date 2022-09-27
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2766-5526
    ISSN (online) 2766-5526
    DOI 10.1056/EVIDccon2200084
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Has the Time Come to Be More Aggressive With Bariatric Surgery in Obese Patients With Chronic Systolic Heart Failure?

    Vest, Amanda R

    Current heart failure reports

    2018  Volume 15, Issue 3, Page(s) 171–180

    Abstract: Purpose of review: Obesity is a strong risk factor for the development of heart failure (HF). Diet, exercise, and weight-loss pharmacotherapies have limited potential to achieve significant and sustainable weight loss, especially in patients with ... ...

    Abstract Purpose of review: Obesity is a strong risk factor for the development of heart failure (HF). Diet, exercise, and weight-loss pharmacotherapies have limited potential to achieve significant and sustainable weight loss, especially in patients with symptomatic systolic HF. This review seeks to determine the role of bariatric surgery for patients with systolic HF and obesity.
    Recent findings: Bariatric surgeries such as the laparoscopic sleeve gastrectomy (LSG) and Roux-en-Y gastric bypass (RYGB) represent the most successful long-term strategy for achieving weight loss and diabetes and hypertension remission in the general obese population. These benefits translate to reductions in cardiovascular events and mortality, as well as improvements in myocardial structure and function. There is also now data supporting the safety of LSG or RYGB in patients with systolic dysfunction and a reduction in HF admissions post-operatively. Current literature and clinical experience suggest that the most appropriate bariatric surgery candidates with HF are patients aged < 50-60 years, with severely depressed systolic function and NYHA II-III symptoms, who have failed non-surgical strategies and have a high likelihood of future cardiac transplantation candidacy after weight loss. This review seeks to determine the role of bariatric surgery for patients with systolic HF and obesity.
    MeSH term(s) Bariatric Surgery/methods ; Body Mass Index ; Comorbidity ; Heart Failure, Systolic/epidemiology ; Heart Failure, Systolic/surgery ; Humans ; Obesity/epidemiology ; Obesity/surgery ; Weight Loss/physiology
    Language English
    Publishing date 2018-04-09
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2151202-4
    ISSN 1546-9549 ; 1546-9530
    ISSN (online) 1546-9549
    ISSN 1546-9530
    DOI 10.1007/s11897-018-0390-z
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    Zs.A 5936: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  7. Article ; Online: No Woman Left Behind: Recognizing and Responding to Cardiogenic Shock in Younger Women.

    Vest, Amanda R / Cho, Leslie

    Circulation. Heart failure

    2020  Volume 13, Issue 10, Page(s) e007782

    MeSH term(s) Female ; Heart Failure ; Hospital Mortality ; Humans ; Myocardial Infarction ; Shock, Cardiogenic/diagnosis ; Shock, Cardiogenic/etiology
    Language English
    Publishing date 2020-09-29
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2429459-7
    ISSN 1941-3297 ; 1941-3289
    ISSN (online) 1941-3297
    ISSN 1941-3289
    DOI 10.1161/CIRCHEARTFAILURE.120.007782
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6745: Show issues Location:
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  8. Article ; Online: Links between repeating and growing pattern knowledge and math outcomes in children and adults.

    Borriello, Giulia A / Grenell, Amanda / Vest, Nicholas A / Moore, Kyler / Fyfe, Emily R

    Child development

    2022  Volume 94, Issue 2, Page(s) e103–e118

    Abstract: This study examined repeating and growing pattern knowledge and their associations with procedural and conceptual arithmetic knowledge in a sample of U.S. children (N = 185; ... ...

    Abstract This study examined repeating and growing pattern knowledge and their associations with procedural and conceptual arithmetic knowledge in a sample of U.S. children (N = 185; M
    MeSH term(s) Humans ; Child ; Female ; Adult ; Young Adult ; Male ; Mathematics
    Language English
    Publishing date 2022-12-22
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 215602-7
    ISSN 1467-8624 ; 0009-3920
    ISSN (online) 1467-8624
    ISSN 0009-3920
    DOI 10.1111/cdev.13882
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    Um IV Zs.158: Show issues Location:
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  9. Article ; Online: Sex-specific patterns of donor-derived cell-free DNA in heart transplant rejection: An analysis from the Genomic Research Alliance for Transplantation (GRAfT).

    DeFilippis, Ersilia M / Sweigart, Benjamin / Khush, Kiran K / Shah, Palak / Agbor-Enoh, Sean / Valantine, Hannah A / Vest, Amanda R

    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation

    2024  

    Abstract: Background: Noninvasive methods for surveillance of acute rejection are increasingly used in heart transplantation (HT), including donor-derived cell-free DNA (dd-cfDNA). As other cardiac biomarkers differ by sex, we hypothesized that there may be sex- ... ...

    Abstract Background: Noninvasive methods for surveillance of acute rejection are increasingly used in heart transplantation (HT), including donor-derived cell-free DNA (dd-cfDNA). As other cardiac biomarkers differ by sex, we hypothesized that there may be sex-specific differences in the performance of dd-cfDNA for the detection of acute rejection. The purpose of the current study was to examine patterns of dd-cfDNA seen in quiescence and acute rejection in male and female transplant recipients.
    Methods: Patients enrolled in the Genomic Research Alliance for Transplantation who were ≥18 years at the time of HT were included. Rejection was defined by endomyocardial biopsy with acute cellular rejection (ACR) grade ≥2R and/or antibody-mediated rejection ≥ pAMR 1. dd-cfDNA was quantitated using shotgun sequencing. Median dd-cfDNA levels were compared between sexes during quiescence and rejection. The performance of dd-cfDNA by sex was assessed using area under the receiver operator characteristic (AUROC) curve. Allograft injury was defined as dd-cfDNA ≥0.25%.
    Results: One hundred fifty-one unique patients (49 female, 32%) were included in the analysis with 1,119 available dd-cfDNA measurements. Baseline characteristics including demographics and comorbidities were not significantly different between sexes. During quiescence, there were no significant sex differences in median dd-cfDNA level (0.04% [IQR 0.00, 0.16] in females vs 0.03% [IQR 0.00, 0.12] in males, p = 0.22). There were no significant sex differences in median dd-cfDNA for ACR (0.33% [0.21, 0.36] in females vs 0.32% [0.21, 1.10] in males, p = 0.57). Overall, median dd-cfDNA levels were higher in antibody-mediated rejection (AMR) than ACR but did not significantly differ by sex (0.50% [IQR 0.18, 0.82] in females vs 0.63% [IQR 0.32, 1.95] in males, p = 0.51). Elevated dd-cfDNA detected ACR/AMR with an AUROC of 0.83 in females and 0.89 in males, p-value for comparison = 0.16.
    Conclusions: There were no significant sex differences in dd-cfDNA levels during quiescence and rejection. Performance characteristics were similar, suggesting similar diagnostic thresholds can be used in men and women for rejection surveillance.
    Language English
    Publishing date 2024-03-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1062522-7
    ISSN 1557-3117 ; 1053-2498
    ISSN (online) 1557-3117
    ISSN 1053-2498
    DOI 10.1016/j.healun.2024.03.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2056: Show issues Location:
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  10. Article ; Online: The Heavy Heart: Metabolic Mechanisms and Myocardial Mechanics.

    Vest, Amanda R / Patel, Ayan R

    Circulation. Heart failure

    2017  Volume 10, Issue 5

    MeSH term(s) Heart ; Myocardium ; Systole
    Language English
    Publishing date 2017-05-04
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2429459-7
    ISSN 1941-3297 ; 1941-3289
    ISSN (online) 1941-3297
    ISSN 1941-3289
    DOI 10.1161/CIRCHEARTFAILURE.117.004092
    Database MEDical Literature Analysis and Retrieval System OnLINE

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