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  1. Article: Elevated UV photon fluxes minimally affected cannabinoid concentration in a high-CBD cultivar.

    Westmoreland, F Mitchell / Kusuma, Paul / Bugbee, Bruce

    Frontiers in plant science

    2023  Volume 14, Page(s) 1220585

    Abstract: ... the effect of higher UV photon fluxes. We used fluorescent UV lights with 55% UV-B (280 to 314 nm) and 45% UV ...

    Abstract Ultraviolet photons (UV) can damage critical biochemical processes. Plants synthesize photo-protective pigments that absorb UV to minimize damage. Cannabinoids absorb UV, so increased UV has the potential to increase cannabinoid synthesis. Studies in the 1980's provided some evidence for this hypothesis in low-cannabinoid cultivars, but recent studies did not find an increase in cannabinoid synthesis with increasing UV in high-cannabinoid cultivars. These studies used low UV photon fluxes, so we examined the effect of higher UV photon fluxes. We used fluorescent UV lights with 55% UV-B (280 to 314 nm) and 45% UV-A (315 to 399 nm). Treatments began three weeks after the start of short days and continued for five weeks until harvest. Established weighting factors were used to calculate the daily biologically effective UV photon flux (UV-PFD
    Language English
    Publishing date 2023-08-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2613694-6
    ISSN 1664-462X
    ISSN 1664-462X
    DOI 10.3389/fpls.2023.1220585
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  2. Article: Sustainable

    Westmoreland, F Mitchell / Bugbee, Bruce

    Frontiers in plant science

    2022  Volume 13, Page(s) 1015652

    Abstract: Phosphorus (P) is an essential but often over-applied nutrient in agricultural systems. Because of its detrimental environmental effects, P fertilization is well studied in crop production. Controlled environment agriculture allows for precise control of ...

    Abstract Phosphorus (P) is an essential but often over-applied nutrient in agricultural systems. Because of its detrimental environmental effects, P fertilization is well studied in crop production. Controlled environment agriculture allows for precise control of root-zone P and has the potential to improve sustainability over field agriculture. Medical
    Language English
    Publishing date 2022-11-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2613694-6
    ISSN 1664-462X
    ISSN 1664-462X
    DOI 10.3389/fpls.2022.1015652
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  3. Article: Prize Essays.

    Banks, J T / Westmoreland, J G / Dannelly, F O / Drewry, N B / O'Keefe, D C

    Atlanta medical and surgical journal

    2022  Volume 7B, Issue 8, Page(s) 380–381

    Language English
    Publishing date 2022-07-11
    Publishing country United States
    Document type Journal Article
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Changes in Health Insurance During COVID-19 Among a U.S. National Cohort of Cisgender Gay and Bisexual Men and Transgender Individuals.

    D'Angelo, Alexa B / Zohra, Fatima / Westmoreland, Drew A / Grov, Christian

    Annals of LGBTQ public and population health

    2022  Volume 4, Issue 3, Page(s) 232–250

    Abstract: The extant data suggest that LGBT communities were disproportionately impacted by the economic ramifications of the pandemic and were more likely to report being uninsured throughout the first two years of the pandemic. Additionally, these groups are at ... ...

    Abstract The extant data suggest that LGBT communities were disproportionately impacted by the economic ramifications of the pandemic and were more likely to report being uninsured throughout the first two years of the pandemic. Additionally, these groups are at heightened vulnerability for several health conditions that require insurance to manage or prevent. Thus, there is a need to assess changes in pandemic-era insurance coverage among these populations. This study uses data collected as part of the
    Language English
    Publishing date 2022-07-20
    Publishing country United States
    Document type Journal Article
    ISSN 2688-4518
    ISSN (online) 2688-4518
    DOI 10.1891/lgbtq-2022-0001
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  5. Article ; Online: Cannabis lighting: Decreasing blue photon fraction increases yield but efficacy is more important for cost effective production of cannabinoids.

    Westmoreland, F Mitchell / Kusuma, Paul / Bugbee, Bruce

    PloS one

    2021  Volume 16, Issue 3, Page(s) e0248988

    Abstract: LED technology facilitates a range of spectral quality, which can be used to optimize photosynthesis, plant shape and secondary metabolism. We conducted three studies to investigate the effect of blue photon fraction on yield and quality of medical hemp. ...

    Abstract LED technology facilitates a range of spectral quality, which can be used to optimize photosynthesis, plant shape and secondary metabolism. We conducted three studies to investigate the effect of blue photon fraction on yield and quality of medical hemp. Conditions were varied among studies to evaluate potential interactions with environment, but all environmental conditions other than the blue photon fraction were maintained constant among the five-chambers in each study. The photosynthetic photon flux density (PPFD, 400 to 700 nm) was rigorously maintained at the set point among treatments in each study by raising the fixtures. The lowest fraction of blue photons was 4% from HPS, and increased to 9.8, 10.4, 16, and 20% from LEDs. There was a consistent, linear, 12% decrease in yield in each study as the fraction of blue photons increased from 4 to 20%. Dry flower yield ranged from 500 to 750 g m-2. This resulted in a photon conversion efficacy of 0.22 to 0.36 grams dry flower mass yield per mole of photons. Yield was higher at a PPFD of 900 than at 750 μmol m-2 s-1. There was no effect of spectral quality on CBD or THC concentration. CBD and THC were 8% and 0.3% at harvest in trials one and two, and 12% and 0.5% in trial three. The CBD/THC ratio was about 25 to 1 in all treatments and studies. The efficacy of the fixtures ranged from 1.7 (HPS) to 2.5 μmol per joule (white+red LED). Yield under the white+red LED fixture (10.4% blue) was 4.6% lower than the HPS on a per unit area basis, but was 27% higher on a per dollar of electricity basis. These findings suggest that fixture efficacy and initial cost of the fixture are more important for return on investment than spectral distribution at high photon flux.
    MeSH term(s) Cannabinoids/biosynthesis ; Cannabinoids/economics ; Cannabis/metabolism ; Color ; Cost-Benefit Analysis ; Electricity ; Photons ; Time Factors
    Chemical Substances Cannabinoids
    Language English
    Publishing date 2021-03-23
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0248988
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  6. Article ; Online: Photons from NIR LEDs can delay flowering in short-day soybean and Cannabis: Implications for phytochrome activity.

    Kusuma, Paul / Westmoreland, F Mitchell / Zhen, Shuyang / Bugbee, Bruce

    PloS one

    2021  Volume 16, Issue 7, Page(s) e0255232

    Abstract: Photons during the dark period delay flowering in short-day plants (SDP). Red photons applied at night convert phytochromes to the active far-red absorbing form (Pfr), leading to inhibition of flowering. Far-red photons (greater than 700 nm) re-induce ... ...

    Abstract Photons during the dark period delay flowering in short-day plants (SDP). Red photons applied at night convert phytochromes to the active far-red absorbing form (Pfr), leading to inhibition of flowering. Far-red photons (greater than 700 nm) re-induce flowering when applied after a pulse of red photons during the dark period. However, far-red photons at sufficiently high intensity and duration delay flowering in sensitive species. Mechanistically, this response occurs because phytochrome-red (Pr) absorbance is not zero beyond 700 nm. We applied nighttime photons from near infrared (NIR) LEDs (peak 850 nm) over a 12 h dark period. Flowering was delayed in Glycine max and Cannabis sativa (two photosensitive species) by 3 and 12 days, respectively, as the flux of photons from NIR LEDs was increased up to 83 and 116 μmol m-2 s-1. This suggests that long wavelength photons from NIR LEDs can activate phytochromes (convert Pr to Pfr) and thus alter plant development.
    MeSH term(s) Cannabis/growth & development ; Cannabis/metabolism ; Cannabis/radiation effects ; Flowers/growth & development ; Flowers/metabolism ; Flowers/radiation effects ; Infrared Rays ; Photons ; Phytochrome/metabolism ; Plant Stems/growth & development ; Plant Stems/metabolism ; Plant Stems/radiation effects ; Glycine max/growth & development ; Glycine max/metabolism ; Glycine max/radiation effects
    Chemical Substances Phytochrome (11121-56-5)
    Language English
    Publishing date 2021-07-27
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0255232
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Sexual and Gender Minorities' Vaccine Uptake and Behavioral Change in Response to the Mpox Outbreak in the United States: August 2022 Through November 2022.

    Grov, Christian / Zohra, Fatima / Mirzayi, Chloe / Stief, Matthew / D'Angelo, Alexa B / Dearolf, Michelle / Westmoreland, Drew A / Carneiro, Pedro / Nash, Denis / Carrico, Adam W

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

    2024  

    Abstract: Background: In the summer of 2022, the United States faced a nationwide outbreak of mpox, with cases concentrated in sexual and gender minorities who have sex with men. Understanding rates of mpox vaccine uptake and concomitant behavioral change is ... ...

    Abstract Background: In the summer of 2022, the United States faced a nationwide outbreak of mpox, with cases concentrated in sexual and gender minorities who have sex with men. Understanding rates of mpox vaccine uptake and concomitant behavioral change is essential to guide the implementation of targeted public health responses to the potential reemergence of mpox.
    Methods: Between August 2022 and November 2022, 8551 individuals recruited via geosocial networking apps completed a brief survey that assessed mpox vaccine uptake, intentions to get a mpox vaccine, and behavioral change.
    Results: In August, 17.4% of participants reported having received at least 1 dose of the mpox vaccine. By November, this prevalence estimate was 35.0%. Black participants were significantly less likely to be vaccinated, and vaccine hesitancy increased among Black participants over time. Among those who had not yet received a vaccination, the intention to get vaccinated decreased over time. We observed trends that coincided with the evolving outbreak, such as decreased worry about mpox and less engagement in risk reduction behaviors over time.
    Conclusions: Despite a 2-fold increase in mpox vaccine uptake between August 2022 and November 2022 in sexual and gender minorities who have sex with men, disparities in vaccine uptake were observed among Black participants. Findings will guide the implementation of public health responses to the potential reemergence of mpox and other viral infectious diseases (eg, meningitis) with a specific focus on optimizing vaccine uptake in Black communities.
    Language English
    Publishing date 2024-01-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1093/cid/ciad793
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1505: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 480: Show issues

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  8. Article: Update on pathology laboratory development and research in advancing regional cancer care in Malawi.

    Brownlee, Amy J / Dewey, Morgan / Chagomerana, Maganizo B / Tomoka, Tamiwe / Mulenga, Maurice / Khan, Shiraz / Kampani, Coxcilly / Chimzimu, Fred / Gastier-Foster, Julie M / Westmoreland, Kate D / Ozuah, Nmazuo W / Krysiak, Robert / Malamba-Banda, Chikondi / Painschab, Matthew S / Gopal, Satish / Fedoriw, Yuri

    Frontiers in medicine

    2024  Volume 11, Page(s) 1336861

    Abstract: The pathology laboratory at Kamuzu Central Hospital (KCH) in Lilongwe, Malawi was established in 2011. We published our initial experiences in laboratory development and telepathology in 2013 and 2016, respectively. The purpose of this paper is to ... ...

    Abstract The pathology laboratory at Kamuzu Central Hospital (KCH) in Lilongwe, Malawi was established in 2011. We published our initial experiences in laboratory development and telepathology in 2013 and 2016, respectively. The purpose of this paper is to provide an update on our work by highlighting the positive role laboratory development has played in improving regional cancer care and research. In addition, we provide a summary of the adult pathology data from specimens received between July 1, 2011, and May 31, 2019, with an emphasis on malignant diagnoses. We compare these summaries to estimates of cancer incidence in this region to identify gaps and future needs.
    Language English
    Publishing date 2024-01-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2024.1336861
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  9. Article ; Online: A Bond-Energy/Bond-Order and Populations Relationship.

    Zulueta, Barbaro / Tulyani, Sonia V / Westmoreland, Phillip R / Frisch, Michael J / Petersson, E James / Petersson, George A / Keith, John A

    Journal of chemical theory and computation

    2022  Volume 18, Issue 8, Page(s) 4774–4794

    Abstract: ... B, C, N, O, and F atoms, and it can be used to analyze intramolecular bond energies ...

    Abstract We report an analytical bond energy from bond orders and populations (BEBOP) model that provides intramolecular bond energy decompositions for chemical insight into the thermochemistry of molecules. The implementation reported here employs a minimum basis set Mulliken population analysis on well-conditioned Hartree-Fock orbitals to decompose total electronic energies into physically interpretable contributions. The model's parametrization scheme is based on atom-specific parameters for hybridization and atom pair-specific parameters for short-range repulsion and extended Hückel-type bond energy term fitted to reproduce CBS-QB3 thermochemistry data. The current implementation is suitable for molecules involving H, Li, Be, B, C, N, O, and F atoms, and it can be used to analyze intramolecular bond energies of molecular structures at optimized stationary points found from other computational methods. This first-generation model brings the computational cost of a Hartree-Fock calculation using a large triple-ζ basis set, and its atomization energies are comparable to those from widely used hybrid Kohn-Sham density functional theory (DFT, as benchmarked to 109 species from the G2/97 test set and an additional 83 reference species). This model should be useful for the community by interpreting overall
    MeSH term(s) Density Functional Theory ; Molecular Structure ; Thermodynamics
    Language English
    Publishing date 2022-07-18
    Publishing country United States
    Document type Journal Article
    ISSN 1549-9626
    ISSN (online) 1549-9626
    DOI 10.1021/acs.jctc.2c00334
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  10. Article: Periodic lateralized epileptiform discharges after evacuation of subdural hematomas.

    Westmoreland, B F

    Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society

    2001  Volume 18, Issue 1, Page(s) 20–24

    Abstract: Periodic lateralized epileptiform discharges (PLEDs) have been recorded in some patients with subdural hematomas. In most of the patients, PLEDs occurred before the hematoma was evacuated. Five patients (three men and two women) who ranged in age from 57 ...

    Abstract Periodic lateralized epileptiform discharges (PLEDs) have been recorded in some patients with subdural hematomas. In most of the patients, PLEDs occurred before the hematoma was evacuated. Five patients (three men and two women) who ranged in age from 57 to 88 years had PLEDs and seizures after evacuation of a subdural hematoma. The PLEDs occurred 1 to 9 days after evacuation and were associated with clinical seizures and altered consciousness. After treatment with anticonvulsant agents, the PLEDs and seizures resolved. The presence of PLEDs should be considered in patients who, after evacuation of a subdural hematoma, have altered consciousness, lateralized neurologic findings, or seizurelike activity (or a combination of these features).
    MeSH term(s) Aged ; Aged, 80 and over ; Electroencephalography/methods ; Female ; Hematoma, Subdural/complications ; Hematoma, Subdural/surgery ; Humans ; Male ; Middle Aged ; Postoperative Complications/diagnosis ; Postoperative Complications/etiology ; Seizures/diagnosis ; Seizures/etiology
    Language English
    Publishing date 2001-03-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 605640-4
    ISSN 1537-1603 ; 0736-0258
    ISSN (online) 1537-1603
    ISSN 0736-0258
    DOI 10.1097/00004691-200101000-00005
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1921: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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