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  1. Article ; Online: Surgical Outcomes of Minimally Invasive Trephine Surgery for Pilonidal Sinus Disease and Risk Factors for Recurrence.

    Khalilieh, Saed / Horesh, Nir / Cordoba, Mordehay / Forschmidt, Eyal / Zager, Yaniv / Nadler, Roy / Gutman, Mordechai / Rosin, Danny / Ram, Edward

    Journal of laparoendoscopic & advanced surgical techniques. Part A

    2021  Volume 32, Issue 3, Page(s) 288–292

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Adult ; Humans ; Minimally Invasive Surgical Procedures/methods ; Neoplasm Recurrence, Local/etiology ; Pilonidal Sinus/surgery ; Prospective Studies ; Recurrence ; Risk Factors ; Treatment Outcome
    Language English
    Publishing date 2021-05-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1381909-4
    ISSN 1557-9034 ; 1092-6429
    ISSN (online) 1557-9034
    ISSN 1092-6429
    DOI 10.1089/lap.2021.0097
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Development and Utilization of a Medical Student Surgery Podcast During COVID-19.

    Anteby, Roi / Amiel, Imri / Cordoba, Mordehay / Axelsson, Carl Gustaf S / Rosin, Danny / Phitayakorn, Roy

    The Journal of surgical research

    2021  Volume 265, Page(s) 95–99

    Abstract: Background: The 2019 coronavirus disease (COVID-19) pandemic drastically reduced learning opportunities for medical students. We sought to determine the cost and success of implementation of a podcast for a surgical department in a large academic ... ...

    Abstract Background: The 2019 coronavirus disease (COVID-19) pandemic drastically reduced learning opportunities for medical students. We sought to determine the cost and success of implementation of a podcast for a surgical department in a large academic hospital.
    Methods: We created a podcast series for Israeli medical students during the COVID-19 epidemic based on the Medical Student Core Curriculum of the American College of Surgeons / Association for Surgical Education. Episodes were available for free download or streaming on a designated website and popular podcast platforms. Podcast analytics were used to measure public listeners and uptake.
    Results: Total development time was 90 hours at an estimated cost of $7091 USD. A total of 10 episodes were released between March 21, 2020 and August 31, 2020. An average of 9 ± 1.26 h (range 2-6) was required to generate each episode, including 3.4 ± 1.26 h (2-6) for content review and 5.6 ± 2 h (4-10) for audio production. An average episode ran for 35.9 ± 4.3 min (28-42). Podcasts recorded a total of 5678 downloads, with an average of 228 and 336 downloads per episode in the first 30 and 90 days, respectively. The average daily downloads before the students returned to clinical rotations (March 21-April 30) was 48 ± 58.3 (7-283;) compared to 16 ± 7.4 after their return (1-38; P< 0.01). Estimated costs to produce a video-based education series would have been significantly more.
    Conclusion: Podcasts can serve as a cost-effective and quickly produced instructional tool to supplement online learning. Further research is required to determine the efficacy of podcasts versus video-based education modules.
    MeSH term(s) COVID-19/epidemiology ; Costs and Cost Analysis ; Education, Medical ; General Surgery/education ; Humans ; SARS-CoV-2 ; Students, Medical ; Webcasts as Topic
    Language English
    Publishing date 2021-04-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80170-7
    ISSN 1095-8673 ; 0022-4804
    ISSN (online) 1095-8673
    ISSN 0022-4804
    DOI 10.1016/j.jss.2021.03.059
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The Impact of the Coronavirus Disease 2019 Outbreak on the Attendance of Patients with Surgical Complaints at a Tertiary Hospital Emergency Department.

    Anteby, Roi / Zager, Yaniv / Barash, Yiftach / Nadler, Roy / Cordoba, Mordehay / Klang, Eyal / Klein, Yoram / Ram, Edward / Gutman, Mordechai / Horesh, Nir

    Journal of laparoendoscopic & advanced surgical techniques. Part A

    2020  Volume 30, Issue 9, Page(s) 1001–1007

    Abstract: Introduction: ...

    Abstract Introduction:
    MeSH term(s) Adolescent ; Adult ; Aged ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/epidemiology ; Emergency Service, Hospital/statistics & numerical data ; Female ; Health Personnel ; Hospitalization ; Humans ; Intestinal Diseases/epidemiology ; Israel/epidemiology ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/epidemiology ; Retrospective Studies ; SARS-CoV-2 ; Sex Factors ; Surgery Department, Hospital/statistics & numerical data ; Tachycardia/epidemiology ; Tertiary Care Centers/statistics & numerical data ; Young Adult
    Keywords covid19
    Language English
    Publishing date 2020-06-23
    Publishing country United States
    Document type Journal Article ; Observational Study
    ZDB-ID 1381909-4
    ISSN 1557-9034 ; 1092-6429
    ISSN (online) 1557-9034
    ISSN 1092-6429
    DOI 10.1089/lap.2020.0465
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Associations of novel inflammatory markers with long-term outcomes and recurrence of diverticulitis.

    Zager, Yaniv / Horesh, Nir / Dan, Assaf / Aharoni, Mor / Khalilieh, Saed / Cordoba, Mordehay / Nevler, Avinoam / Gutman, Mordechai / Rosin, Danny

    ANZ journal of surgery

    2020  Volume 90, Issue 10, Page(s) 2041–2045

    Abstract: Background: The neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) have emerged as markers of various outcomes of inflammatory and malignant diseases. The association of those markers with short-term outcomes of acute ... ...

    Abstract Background: The neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) have emerged as markers of various outcomes of inflammatory and malignant diseases. The association of those markers with short-term outcomes of acute diverticulitis has been discussed in recent studies. This study aimed at evaluation of the association of NLR and PLR with long-term outcomes in patients presenting with acute diverticulitis.
    Methods: A retrospective single institute study included patients admitted with acute diverticulitis between 2012 and 2016. Associations were analysed of NLR and PLR values at admission with patient outcomes.
    Results: A total of 456 patients were included in the study. High NLR and PLR values were associated with complicated disease (P < 0.01 for both). Among patients with complicated diverticulitis, for those with high NLR, the interval to a recurrent episode of acute diverticulitis was shorter (68.3 days versus 83.7 days, P = 0.044). Patients with high NLR had higher mean number of readmissions (0.54 versus 0.34, P = 0.035). High NLR (10.06 ± 11.23 versus 7.6 ± 8.04, P = 0.012) and PLR (9.64 days ±10.56 versus 7.47 days ±8.225, P = 0.018) were associated with longer cumulative hospital stay due to acute diverticulitis.
    Conclusions: High NLR and PLR values were associated with recurrence in acute diverticulitis in terms of shorter interval between recurrent episodes and longer cumulative hospitalization days.
    MeSH term(s) Blood Platelets ; Diverticulitis ; Humans ; Lymphocytes ; Neutrophils ; Platelet Count ; Prognosis ; Retrospective Studies
    Language English
    Publishing date 2020-08-28
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2050749-5
    ISSN 1445-2197 ; 1445-1433 ; 0004-8682
    ISSN (online) 1445-2197
    ISSN 1445-1433 ; 0004-8682
    DOI 10.1111/ans.16220
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy in patients with peritoneal carcinomatosis from colorectal cancer: The prognostic impact of baseline neutrophil-lymphocyte, platelet-lymphocyte and lymphocyte-monocyte ratios.

    Zager, Yaniv / Hoffman, Aviad / Dreznik, Yael / Jacoby, Harel / Cordoba, Mordehay / Horesh, Nir / Nevler, Avinoam / Gutman, Mordechai / Berger, Yaniv

    Surgical oncology

    2020  Volume 35, Page(s) 321–327

    Abstract: Purpose: In this retrospective analysis we sought to determine if the preoperative neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR) and lymphocyte-monocyte ratio (LMR) were predictive of both operability and survival in those patients ... ...

    Abstract Purpose: In this retrospective analysis we sought to determine if the preoperative neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR) and lymphocyte-monocyte ratio (LMR) were predictive of both operability and survival in those patients presenting with peritoneal carcinomatosis (PC) from colorectal cancer (CRC) who underwent cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS-HIPEC).
    Methods: Analysis included all patients admitted between 2009 and 2017 with PC from CRC who were treated with curative intent by CRS-Mitomycin C-HIPEC. Patients were assessed pre- and intra-operatively by the PC index (PCI) and by a completeness of cytoreduction (CC) score with calculation of Kaplan-Meier survival curves and multivariate analysis of prognostic factors. Discrimination was made for NLR >3.5, PLR >168.8 and LMR >4.4.
    Results: We identified 98 CRC patients undergoing 105 CRS-HIPEC procedures. There were no associations detected between NLR/PLR/LMR and the rates of incomplete or abandoned CRS cases. Overall survival (OS) after CRS-HIPEC was worse with high versus low NLR (19.9 mths vs. 45.7 mths, respectively; P = 0.009) and also with low versus high LMR (27.1 mths vs. 53.2 mths, respectively; P = 0.01). On multivariate analysis, a low LMR (P = 0.008), the preoperative CT PCI value (P = 0.004), poor tumor differentiation (P = 0.023) and the preoperative CEA level (P < 0.001) were all independent variables associated with a worse OS after surgery.
    Conclusions: The baseline LMR value may have potential value as a selection tool for CRS-HIPEC in patients with CRC-related PC.
    MeSH term(s) Aged ; Blood Platelets ; Colorectal Neoplasms/blood ; Colorectal Neoplasms/drug therapy ; Colorectal Neoplasms/pathology ; Colorectal Neoplasms/surgery ; Combined Modality Therapy ; Cytoreduction Surgical Procedures ; Female ; Humans ; Hyperthermic Intraperitoneal Chemotherapy ; Israel ; Lymphocytes ; Male ; Middle Aged ; Monocytes ; Neutrophils ; Peritoneal Neoplasms/secondary ; Prognosis ; Treatment Outcome
    Language English
    Publishing date 2020-09-14
    Publishing country Netherlands
    Document type Comparative Study ; Journal Article
    ZDB-ID 1107810-8
    ISSN 1879-3320 ; 0960-7404
    ISSN (online) 1879-3320
    ISSN 0960-7404
    DOI 10.1016/j.suronc.2020.09.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: The Effect of the COVID-19 Outbreak on Trauma-Related Visits to a Tertiary Hospital Emergency Department.

    Cordoba, Mordehay / Anteby, Roi / Zager, Yaniv / Barash, Yiftach / Klang, Eyal / Nadler, Roy / Amiel, Imri / Gutman, Mordechai / Horesh, Nir / Aviran, Nimrod / Klein, Yoram

    The Israel Medical Association journal : IMAJ

    2021  Volume 23, Issue 2, Page(s) 82–86

    Abstract: Background: The novel coronavirus disease (COVID-19) pandemic changed medical environments worldwide.: Objectives: To evaluate the impact of the COVID-19 pandemic on trauma-related visits to the emergency department (ED).: Methods: A single ... ...

    Abstract Background: The novel coronavirus disease (COVID-19) pandemic changed medical environments worldwide.
    Objectives: To evaluate the impact of the COVID-19 pandemic on trauma-related visits to the emergency department (ED).
    Methods: A single tertiary center retrospective study was conducted that compared ED attendance of patients with injury-related morbidity between March 2020 (COVID-19 outbreak) and pre-COVID-19 periods: February 2020 and the same 2 months in 2018 and 2019.
    Results: Overall, 6513 patients were included in the study. During the COVID-19 outbreak, the daily number of patients visiting the ED for acute trauma declined by 40% compared to the average in previous months (P < 0.01). A strong negative correlation was found between the number of trauma-related ED visits and the log number of confirmed cases of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) in Israel (Pearson's r = -0.63, P < 0.01). In the COVID-19 period there was a significant change in the proportion of elderly patients (7% increase, P = 0.002), admissions ratio (12% increase, P < 0.001), and patients brought by emergency medical services (10% increase, P < 0.001). The number of motor vehicle accident related injury declined by 45% (P < 0.01).
    Conclusions: A significant reduction in the number of trauma patients presenting to the ED occurred during the COVID-19 pandemic, yet trauma-related admissions were on the rise.
    MeSH term(s) Accidents, Traffic/statistics & numerical data ; Adolescent ; Adult ; Age Distribution ; Aged ; COVID-19/epidemiology ; Cross-Sectional Studies ; Emergency Medical Services/statistics & numerical data ; Emergency Service, Hospital/statistics & numerical data ; Female ; Hospitalization/statistics & numerical data ; Humans ; Israel/epidemiology ; Male ; Middle Aged ; Retrospective Studies ; Tertiary Care Centers ; Wounds and Injuries/epidemiology ; Wounds and Injuries/therapy ; Young Adult
    Language English
    Publishing date 2021-02-17
    Publishing country Israel
    Document type Journal Article
    ZDB-ID 2008291-5
    ISSN 1565-1088 ; 0021-2180
    ISSN 1565-1088 ; 0021-2180
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: The Impact of the Coronavirus Disease 2019 Outbreak on the Attendance of Patients with Surgical Complaints at a Tertiary Hospital Emergency Department

    Anteby, Roi / Zager, Yaniv / Barash, Yiftach / Nadler, Roy / Cordoba, Mordehay / Klang, Eyal / Klein, Yoram / Ram, Edward / Gutman, Mordechai / Horesh, Nir

    J. laparoendosc. adv. surg. tech., Part A

    Abstract: Introduction: Emergency departments (EDs) during the novel coronavirus disease 2019 (COVID-19) pandemic are perceived as possible sources of infection. The effects of COVID-19 on patients presenting to the hospital with surgical complaints remain ... ...

    Abstract Introduction: Emergency departments (EDs) during the novel coronavirus disease 2019 (COVID-19) pandemic are perceived as possible sources of infection. The effects of COVID-19 on patients presenting to the hospital with surgical complaints remain uncertain. Methods: A single tertiary center retrospective study analysis compared the ED attendance rate and severity of patients with surgical complaints between March 2020 (COVID-19 outbreak) and pre-COVID-19 periods: February 2020 and the same 2 months in 2019 and 2018. Results: Overall, 6,017 patients were included. The mean daily ED visits of patients with nontrauma surgical complaints in the COVID-19 outbreak period declined by 27%-32% (P value <.01) compared with pre-COVID-19 periods. The log number of confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cases in Israel in March 2020 was negatively correlated with the number of ED visits (Pearson's r = -0.59, P < .01). The proportion of patients requiring hospitalization increased by up to 8% during the outbreak period (P < .01), and there was a higher proportion of tachycardic patients (20% versus 15.5%, P = .01). The percentage of visits to the ED by men declined by 5% (P < .01). The ED diagnosis distribution significantly changed during COVID-19 (P = .013), with an 84% decrease in the number of patients hospitalized for diverticular disease (P < .05). Conclusion: During the COVID-19 outbreak, the overall number of patients presenting at the ED with surgical complaints decreased significantly, and there was a higher admissions ratio. The extent to which the pandemic affects hospital ED attendance can help health care professionals prepare for future such events. ClinicalTrials.gov ID: NCT04338672.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #32589496
    Database COVID19

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