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Article ; Online: Q&A with Guang-Hui Liu.

Liu, Guang-Hui

2023 Volume 42, Issue 8, Page(s) 112862

Abstract: We at Cell Reports discuss with Guang-Hui Liu his work with the mechanisms and interventions ...

Abstract	We at Cell Reports discuss with Guang-Hui Liu his work with the mechanisms and interventions of aging, in particular, recent work regarding the resurrection of endogenous retroviruses in neurons in primates.
Language	English
Publishing date	2023-07-27
Publishing country	United States
Document type	Journal Article
ZDB-ID	2649101-1
ISSN	2211-1247 ; 2211-1247
ISSN (online)	2211-1247
ISSN	2211-1247
DOI	10.1016/j.celrep.2023.112862
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Article ; Online: Analysis on status quo and related factors of delays in diagnosis and treatment of breast cancer in Ningxia Hui Autonomous Region.

Wang, Yuchen / Bai, Zhoulan / Liu, Qingyuan / Yu, Hui / Tang, Zhenning / Liu, Xiang / Liu, Qilun

Medicine

2024 Volume 103, Issue 17, Page(s) e37826

Abstract: ... of breast cancer (BC) in Ningxia Hui Autonomous Region. We conducted a cohort analysis of 1012 patients ...

Abstract	This study aimed to explore factors contributing to the delays in the diagnosis and treatment of breast cancer (BC) in Ningxia Hui Autonomous Region. We conducted a cohort analysis of 1012 patients with BC diagnosed at the General Hospital of Ningxia Medical University between January 2018 and December 2019. Sociodemographic data were collected through questionnaires, and clinical data were gathered and analyzed from relevant databases. Furthermore, observations were made regarding delays in the diagnosis and treatment of BC, followed by an analysis of the correlations between patient delay and both sociological factors within the population and clinical factors specific to patients with BC. Subsequently, the factors associated with patient delay and system delay were examined using Cox regression analysis, along with the inclusion of neoadjuvant therapy. In the prevention and treatment of BC in Ningxia, the patient delay rate was 33.20%, the diagnosis delay rate was 17.89%, the treatment delay rate was 0.0099% and the system delay rate was 41.60%. There was a higher proportion of patient delay and system delay in aged patients (age ≥ 61 years) with rural registered permanent residence (RPR), multiple clinical symptoms (such as nipple spillage, axillary abnormalities, etc), a T4 tumor size classification, and the initial use of neoadjuvant therapy. Besides, significant positive correlations were observed between patient delay and system delay time with BC stage. Patients aged 51 to 60 and those with molecular types (Limanal1B: ki-67 > 14%, Limanal1B: HER-2 positive) were prone to patient delay, whereas molecular characteristics influenced system delay, unrelated to sociodemographic factors. The study identifies significant age, residency, and tumor molecular subtype correlations with diagnostic and treatment delays in Ningxia's patients with BC, predominantly affecting women aged 41 to 60, especially urban dwellers. These findings underscore the need for targeted interventions to reduce delays and improve BC care in this region.
MeSH term(s)	Humans ; Breast Neoplasms/therapy ; Breast Neoplasms/diagnosis ; Female ; Middle Aged ; Time-to-Treatment/statistics & numerical data ; Delayed Diagnosis/statistics & numerical data ; China/epidemiology ; Adult ; Aged ; Neoadjuvant Therapy/statistics & numerical data ; Neoadjuvant Therapy/methods ; Age Factors
Language	English
Publishing date	2024-04-26
Publishing country	United States
Document type	Journal Article ; Observational Study
ZDB-ID	80184-7
ISSN	1536-5964 ; 0025-7974
ISSN (online)	1536-5964
ISSN	0025-7974
DOI	10.1097/MD.0000000000037826
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Article ; Online: Performance evaluation of an in-house panel containing 59 autosomal InDels for forensic identification in Chinese Hui and Mongolian groups.

Fang, Yating / Liu, Yanfang / Xu, Hui / Zhu, Bofeng

Genomics

2022 Volume 115, Issue 1, Page(s) 110552

Abstract: ... of these loci were investigated in Chinese Hui (n = 249) and Mongolian (n = 222) ethnic groups using direct ... that the values of the combined power of discrimination were 0.9999999999999999999999999999006 (Hui) and 0 ... 999999999999999999999999999738 (Mongolian), respectively. Moreover, the combined power of exclusion values were 0.99999817 (Hui ...

Abstract	In recent years, a novel multiplex system containing two mini-short tandem repeats, 59 autosomal InDels, two Y-chromosomal InDels, and the Amelogenin gene with all amplicons less than 200 bp has been constructed and validated by ourselves for forensic degration sample, and its forensic application efficiency has been studied in Chinese some populations. Herein, the population genetic polymorphisms of these loci were investigated in Chinese Hui (n = 249) and Mongolian (n = 222) ethnic groups using direct multiplex amplification and capillary electrophoresis platform. The forensic identification efficiencies of this self-developed system were further evaluated in these two groups. And the results showed that the values of the combined power of discrimination were 0.9999999999999999999999999999006 (Hui) and 0.999999999999999999999999999738 (Mongolian), respectively. Moreover, the combined power of exclusion values were 0.99999817 (Hui) and 0.99999779 (Mongolian). The 59 autosomal InDels used in this study exhibited high forensic identification efficiencies in 10 East Asian populations, which was also expected to be a new powerful tool for identifying degraded biological materials in East Asian populations.
MeSH term(s)	Humans ; Asian People/genetics ; China ; East Asian People ; Gene Frequency ; Genetics, Population ; INDEL Mutation ; Microsatellite Repeats ; Polymorphism, Genetic ; Mongolia
Language	English
Publishing date	2022-12-21
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	356334-0
ISSN	1089-8646 ; 0888-7543
ISSN (online)	1089-8646
ISSN	0888-7543
DOI	10.1016/j.ygeno.2022.110552
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Article: [Summary of Hui prescriptions for treating cough].

Zhang, Wen-jin / Liu, Yue / Zhang, Xin-hui

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

2015 Volume 40, Issue 4, Page(s) 753–757

Abstract: ... therapy has been screened out from Hui medicine through collecting the ancient and modern literature ... summarizing the common drugs of Hui medicine for asthma are Pinellia, almond, white sugar, walnut. According ... to the commonly used drugs, the pathogeny and treatment principle about Hui medicine for asthma is preliminarily ...

Abstract	In this study, by using the method of literature research, 35 prescriptions related to asthma therapy has been screened out from Hui medicine through collecting the ancient and modern literature. A comparison of fragrant medicine between the name in Arab and Chinese herbal medicine is done. The countif function in Microsoft Excel 2007 is used to get the prescriptions of the drug on the frequency statistics, summarizing the common drugs of Hui medicine for asthma are Pinellia, almond, white sugar, walnut. According to the commonly used drugs, the pathogeny and treatment principle about Hui medicine for asthma is preliminarily inferred combining literature research and the related Hui medical theory. In this study, those prescriptions have been classified into 21 cases which are effective and can be used in medical therapy according to the relevant literatures with the development of the Hui people in their long process of formation of the unique diet culture, 14 useful and convenient Halal diet therapies are made up according to the indications, therapies, party name and composition. Halal diet and "medicine and food" herbs are preliminarily analyzed and summarized, which can be convenient for the people to reduce pains through the diet and improve health awareness.
MeSH term(s)	Asthma/drug therapy ; Asthma/ethnology ; China ; Cough/drug therapy ; Cough/ethnology ; Diet/ethnology ; Drug Prescriptions ; Drugs, Chinese Herbal/chemistry ; Drugs, Chinese Herbal/therapeutic use ; Humans ; Medicine, Chinese Traditional
Chemical Substances	Drugs, Chinese Herbal
Language	Chinese
Publishing date	2015-02
Publishing country	China
Document type	English Abstract ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1004649-5
ISSN	1001-5302 ; 0254-0029
ISSN	1001-5302 ; 0254-0029
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Article ; Online: Prevalence of hyperuricaemia among adults from Ningxia Hui Autonomous Region, China: a cross-sectional study.

Shi, Hongjuan / Liu, Yining / Wang, Jinyi / Luan, Hong / Shi, Chao

BMJ open

2023 Volume 13, Issue 10, Page(s) e072408

Abstract: ... its risk factors in the general adult population of Ningxia Hui Autonomous Region (NHAR), China.: Design ...

Abstract	Objective: This study aimed to estimate the prevalence of hyperuricaemia (HUA) and investigate its risk factors in the general adult population of Ningxia Hui Autonomous Region (NHAR), China. Design: Cross-sectional study. Setting: Survey of cardiovascular disorders and their related risk factors in NHAR, China. Participants: 10 803 permanent residents aged 18 and older. Main outcome measures: HUA was defined as serum uric acid levels >420 µmol/L for men and >360 µmol/L for women. Results: The overall prevalence of HUA in NHAR adults was 19.81% (95% CI 19.06 to 20.57), with prevalence values of 24.91% (95% CI 23.70 to 26.14) in men and 15.58% (95% CI 14.66 to 16.53, p<0.001) in women. The prevalence of HUA was higher in urban residents than in rural residents (23.26% vs 17.02%, p<0.001). HUA prevalence was relatively high in individuals younger than 30 years for both men and women, then decreased with age, and began to increase at the age of 40 for women and 60 for men. Higher level of education, being overweight or obese, alcohol consumption, hypertension, diabetes, higher triglycerides, higher total cholesterol and poorer renal function were associated with an increased risk of HUA. Conclusions: HUA prevalence is high among adults in NHAR. Young adults under 30 years and women over 50 years were identified as populations at high risk for HUA. Further attention ought to be placed to promoting healthy diets and implementing early interventions to manage dyslipidaemia, obesity and blood glucose level, as well as advocating for moderation of alcohol consumption.
MeSH term(s)	Male ; Young Adult ; Humans ; Female ; Hyperuricemia/epidemiology ; Cross-Sectional Studies ; Uric Acid ; Prevalence ; Risk Factors ; Obesity ; China/epidemiology
Chemical Substances	Uric Acid (268B43MJ25)
Language	English
Publishing date	2023-10-18
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2599832-8
ISSN	2044-6055 ; 2044-6055
ISSN (online)	2044-6055
ISSN	2044-6055
DOI	10.1136/bmjopen-2023-072408
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Article ; Online: Prevalence of hyperuricaemia among adults from Ningxia Hui Autonomous Region, China

Chao Shi / Hongjuan Shi / Yining Liu / Jinyi Wang / Hong Luan

BMJ Open, Vol 13, Iss

a cross-sectional study

2023 Volume 10

Abstract: ... its risk factors in the general adult population of Ningxia Hui Autonomous Region (NHAR), China.Design ...

Abstract	Objective This study aimed to estimate the prevalence of hyperuricaemia (HUA) and investigate its risk factors in the general adult population of Ningxia Hui Autonomous Region (NHAR), China.Design Cross-sectional study.Setting Survey of cardiovascular disorders and their related risk factors in NHAR, China.Participants 10 803 permanent residents aged 18 and older.Main outcome measures HUA was defined as serum uric acid levels >420 µmol/L for men and >360 µmol/L for women.Results The overall prevalence of HUA in NHAR adults was 19.81% (95% CI 19.06 to 20.57), with prevalence values of 24.91% (95% CI 23.70 to 26.14) in men and 15.58% (95% CI 14.66 to 16.53, p<0.001) in women. The prevalence of HUA was higher in urban residents than in rural residents (23.26% vs 17.02%, p<0.001). HUA prevalence was relatively high in individuals younger than 30 years for both men and women, then decreased with age, and began to increase at the age of 40 for women and 60 for men. Higher level of education, being overweight or obese, alcohol consumption, hypertension, diabetes, higher triglycerides, higher total cholesterol and poorer renal function were associated with an increased risk of HUA.Conclusions HUA prevalence is high among adults in NHAR. Young adults under 30 years and women over 50 years were identified as populations at high risk for HUA. Further attention ought to be placed to promoting healthy diets and implementing early interventions to manage dyslipidaemia, obesity and blood glucose level, as well as advocating for moderation of alcohol consumption.
Keywords	Medicine ; R
Language	English
Publishing date	2023-10-01T00:00:00Z
Publisher	BMJ Publishing Group
Document type	Article ; Online
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Article ; Online: The effect and pharmacology of Yizhi Sheng Hui decoction on Alzheimer's disease.

Li, Qiubing / Hou, Yi / Zhao, Baosheng / Li, Yingfan / Zhang, Xinyu / Mei, Rong / Wang, Shuo / Wang, Peng / Liu, Ying

Annals of palliative medicine

2021 Volume 10, Issue 5, Page(s) 5244–5251

Abstract: ... after treatment with the traditional Chinese medicine compound, Yizhi Sheng Hui (YZSH) decoction. This study ...

Abstract	Background: Alzheimer's disease (AD) has gradually increased as society has aged and is now a serious social problem. In the clinical treatment of AD, patients show improvement in cognitive function after treatment with the traditional Chinese medicine compound, Yizhi Sheng Hui (YZSH) decoction. This study systematically investigates the effect and pharmacology of the YZSH decoction on AD. Methods: In this study, 24 SAMP8 AD model mice were randomly divided into three groups: an untreated control group, a group treated with the YZSH decoction, and a positive control group treated with donepezil hydrochloride. Eight SAMR1 mice were placed in the normal control group. A Morris water maze test and a step-down test were conducted at 8 and 13 weeks after continuous intragastric administration of the two drugs. After 13 weeks of administration, the hippocampal expression of Aβ1-42 and tau protein were measured. Results: There was no change in the latent period duration and the number of platform crossings in each group after 8 weeks of administration, but after 13 weeks of administration, the latent period of the treatment group and the positive control group were significantly shorter than the untreated control group. Initially, the SAMP8 mice showed a lower spatial exploration ability than the SAMR1 mice. However, after 13 weeks of administration, the treatment group and the control group exhibited a better exploration ability. Compared with the SAMR1 mice, the on-stage evasion time and step-down errors significantly increased in the untreated group. Compared with the untreated group, mice in the treatment group and the positive control group showed a shorter latent period after 8 weeks of administration, and the on-stage evasion time for both groups was significantly reduced after 13 weeks of administration. The treatment group showed fewer instances of electric shock. Hippocampal expression of Aβ1-42 was high in the untreated group, was much lower in the positive control group, and no Aβ1-42 expression was observed in the treatment group. Conclusions: The YZSH decoction improved the learning and memory of mice with AD, related to the inhibition of Aβ1-42 expression.
MeSH term(s)	Aged ; Alzheimer Disease/drug therapy ; Animals ; Drugs, Chinese Herbal/therapeutic use ; Humans ; Learning ; Memory ; Mice
Chemical Substances	Drugs, Chinese Herbal ; yi-zhi (1QBV21VOZI)
Language	English
Publishing date	2021-05-14
Publishing country	China
Document type	Journal Article
ZDB-ID	2828544-X
ISSN	2224-5839 ; 2224-5839
ISSN (online)	2224-5839
ISSN	2224-5839
DOI	10.21037/apm-20-1629
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Article: Spatial-temporal changes of landscape and habitat quality in typical ecologically fragile areas of western China over the past 40 years: A case study of the Ningxia Hui Autonomous Region.

Wang, Ding / Hao, Haiguang / Liu, Hao / Sun, Lihui / Li, Yuyang

Ecology and evolution

2024 Volume 14, Issue 1, Page(s) e10847

Abstract: ... to assess the habitat quality of the Ningxia Hui Autonomous Region in Western China, which has ... utilization. The research results show that the overall habitat quality of Ningxia Hui Autonomous Region was ...

Abstract	In this paper, we use the InVEST model and five periods of land use data from 1980 to 2020 to assess the habitat quality of the Ningxia Hui Autonomous Region in Western China, which has characteristics of a typical fragile ecosystem. We further analyse the spatial and temporal characteristics of habitat quality evolution and its relationship with land use and landscape pattern indices to explore the close relationship between regional habitat quality changes and human natural resource conservation and utilization. The research results show that the overall habitat quality of Ningxia Hui Autonomous Region was stable and at a moderate level (0.57-0.60) during the 40 years from 1980 to 2020; Habitat patches (2020) with low (24.89%), high (22.45%) and very high (29.81%) quality occupy a larger proportion of the area, followed by very low (13.31%) and moderate levels (9.54%). Over the past 40 years, there have been 275 sample sites in Ningxia where habitat quality has deteriorated, 1593 sample sites where the habitat quality has remained stable, and 184 sample sites where the habitat quality has increased. From 1980 to 2020, the Mean Patch Area of landscape types in Ningxia decreased by 25.9 hm
Language	English
Publishing date	2024-01-22
Publishing country	England
Document type	Journal Article
ZDB-ID	2635675-2
ISSN	2045-7758
ISSN	2045-7758
DOI	10.1002/ece3.10847
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Article ; Online: Optimization of the N footprint model and analysis of nitrogen pollution in irrigation areas: A case study of Ningxia Hui Autonomous Region, China.

Zhang, Tianpeng / Lei, Qiuliang / Liang, Xia / Lindsey, Stuart / Luo, Jiafa / Pei, Wei / Du, Xinzhong / Wu, Shuxia / An, Miaoying / Qiu, Weiwen / Liu, Hongbin

Journal of environmental management

2023 Volume 340, Page(s) 118002

Abstract: ... in Ningxia Hui Autonomous Region (Ningxia), China, the study assessed the contribution of water diversion to N ...

Abstract	Water diverted from rivers for irrigation areas often contains large amounts of nitrogen (N), which is frequently overlooked and its role in contributing to N pollution is unknown. To investigate the influence of water diversion on N in different systems within irrigation areas, we developed and optimized the N footprint model, taking into account the N carried by irrigation water diversion and drainage in irrigated areas. This optimized model can serve as a reference for evaluating N pollution in other irrigated areas. By analyzing 29 years (1991-2019) of statistical data from a diverted irrigation area in Ningxia Hui Autonomous Region (Ningxia), China, the study assessed the contribution of water diversion to N in agriculture, animal husbandry, and human domestic activities. The results demonstrated that water diversion and drainage accounted for 10.3% and 13.8% in whole system, of the total N input and output in Ningxia, highlighting the potential N pollution risks associated with these activities. Additionally, the use of fertilizers in the plant subsystem, feed in the animal subsystem, and sanitary sewage in the human subsystem represented the main sources of N pollution in each subsystem. On a temporal scale, the study found that N loss increased year by year before reaching a stable level, indicating that N loss had reached its peak in Ningxia. The correlation analysis suggested that rainfall could regulate N input and output in irrigated areas by showing a negative correlation with water diversion, agricultural water consumption, and N from irrigated areas. Moreover, the study revealed that the amount of N brought by water diverted from rivers for irrigation should be taken into account when calculating the amount of fertilizer N required in the irrigation area.
MeSH term(s)	Humans ; Animals ; Nitrogen/analysis ; Agricultural Irrigation/methods ; Environmental Pollution/analysis ; Agriculture/methods ; Water/analysis ; China ; Fertilizers/analysis
Chemical Substances	Nitrogen (N762921K75) ; Water (059QF0KO0R) ; Fertilizers
Language	English
Publishing date	2023-04-27
Publishing country	England
Document type	Journal Article
ZDB-ID	184882-3
ISSN	1095-8630 ; 0301-4797
ISSN (online)	1095-8630
ISSN	0301-4797
DOI	10.1016/j.jenvman.2023.118002
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Article: Externalizing Behavior Problems Among Hui Ethnicity Left-Behind Children in Rural China: A Cross-Sectional Study.

Yu, Xue / Wang, Lingling / Liu, Miaomiao / Li, Qiuli / Dai, Xiuying

Psychiatry investigation

2022 Volume 19, Issue 4, Page(s) 289–301

Abstract: ... and its influencing factors among Hui left-behind children (LBC) in rural China.: Methods ... Results: The prevalence of EBPs in boys Hui LBC was significantly higher than that of non-LBC (12.37% vs ... for the EBPs of Hui LBC, while middle and high father refusal and denial (OR=0.11, OR=0.09) were ...

Abstract	Objective: This study aimed to investigate the prevalence of externalizing behavior problems (EBPs) and its influencing factors among Hui left-behind children (LBC) in rural China. Methods: A cross-sectional study was conducted among school students from the southern rural areas in Ningxia, China (2012-2013). The general self-made questionnaire, Egma Minnen av Bardndosna Uppforstran, Eysenck Personality Questionnaire (for Children), Piers-Harris Children's Self-Concept Scale, and Achenbach's Child Behavior Checklist (for parents) were used to investigate the related information. Binary logistic regressions were conducted. Results: The prevalence of EBPs in boys Hui LBC was significantly higher than that of non-LBC (12.37% vs. 6.84%, χ2=4.09, and p=0.04). Multivariate logistic regression analysis showed that low self-awareness of behavior (odds ratio [OR]=29.78), introversion (OR=21.67) and intermediate personality (OR=15.83), poor academic performance (OR=11.65) and both parent migrating (OR=2.73) were the risk factors for the EBPs of Hui LBC, while middle and high father refusal and denial (OR=0.11, OR=0.09) were their protective factors. Conclusion: Our findings suggest that both parent migrating is a potential risk factor for EBPs among Hui LBC. Hui boys LBC should be paid more attention when formulating relevant policies.
Language	English
Publishing date	2022-04-22
Publishing country	Korea (South)
Document type	Journal Article
ZDB-ID	2414364-9
ISSN	1976-3026 ; 1738-3684
ISSN (online)	1976-3026
ISSN	1738-3684
DOI	10.30773/pi.2021.0119
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