LIVIVO - Search results -

Search results

Result 1 - 10 of total 115

Search options

Book ; Online ; Thesis: Maturation of the Salmonella containing vacuole is compromised in G1 arrested host cells

Lisowski, Clivia [Verfasser] / Eulalio, Ana [Gutachter]

2022

Author's details	Clivia Lisowski ; Gutachter: Ana Eulalio
Keywords	Biowissenschaften, Biologie ; Life Science, Biology
Subject code	sg570
Language	English
Publisher	Universität Würzburg
Publishing place	Würzburg
Document type	Book ; Online ; Thesis
Database	Digital theses on the web

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: C-N linked donor type porphyrin derivatives: unrevealed hole-transporting materials for efficient hybrid perovskite solar cells.

Reis, Melani J A / Nogueira, Ana T / Eulálio, Ana / Moura, Nuno M M / Rodrigues, Joana / Ivanou, Dzmitry / Abreu, Paulo E / Correia, M Rosário P / Neves, Maria G P M S / Pereira, Ana M V M / Mendes, Adélio

Dalton transactions (Cambridge, England : 2003)

2023 Volume 52, Issue 41, Page(s) 14762–14773

Abstract: A new series of Zn(II) and Cu(II)-based porphyrin complexes 5a and 5b doubly functionalised with carbazole units were developed to be used as hole-transporting materials (HTMs) in perovskite solar cells (PSCs). These complexes were ... ...

Abstract	A new series of Zn(II) and Cu(II)-based porphyrin complexes 5a and 5b doubly functionalised with carbazole units were developed to be used as hole-transporting materials (HTMs) in perovskite solar cells (PSCs). These complexes were obtained
Language	English
Publishing date	2023-10-24
Publishing country	England
Document type	Journal Article
ZDB-ID	1472887-4
ISSN	1477-9234 ; 1364-5447 ; 0300-9246 ; 1477-9226
ISSN (online)	1477-9234 ; 1364-5447
ISSN	0300-9246 ; 1477-9226
DOI	10.1039/d3dt00512g
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Article: Biomaterials Based on Organic Polymers and Layered Double Hydroxides Nanocomposites: Drug Delivery and Tissue Engineering.

Constantino, Vera Regina Leopoldo / Figueiredo, Mariana Pires / Magri, Vagner Roberto / Eulálio, Denise / Cunha, Vanessa Roberta Rodrigues / Alcântara, Ana Clecia Santos / Perotti, Gustavo Frigi

Pharmaceutics

2023 Volume 15, Issue 2

Abstract: The development of biomaterials has a substantial role in pharmaceutical and medical strategies for the enhancement of life quality. This review work focused on versatile biomaterials based on nanocomposites comprising organic polymers and a class of ... ...

Abstract	The development of biomaterials has a substantial role in pharmaceutical and medical strategies for the enhancement of life quality. This review work focused on versatile biomaterials based on nanocomposites comprising organic polymers and a class of layered inorganic nanoparticles, aiming for drug delivery (oral, transdermal, and ocular delivery) and tissue engineering (skin and bone therapies). Layered double hydroxides (LDHs) are 2D nanomaterials that can intercalate anionic bioactive species between the layers. The layers can hold metal cations that confer intrinsic biological activity to LDHs as well as biocompatibility. The intercalation of bioactive species between the layers allows the formation of drug delivery systems with elevated loading capacity and modified release profiles promoted by ion exchange and/or solubilization. The capacity of tissue integration, antigenicity, and stimulation of collagen formation, among other beneficial characteristics of LDH, have been observed by in vivo assays. The association between the properties of biocompatible polymers and LDH-drug nanohybrids produces multifunctional nanocomposites compatible with living matter. Such nanocomposites are stimuli-responsive, show appropriate mechanical properties, and can be prepared by creative methods that allow a fine-tuning of drug release. They are processed in the end form of films, beads, gels, monoliths etc., to reach orientated therapeutic applications. Several studies attest to the higher performance of polymer/LDH-drug nanocomposite compared to the LDH-drug hybrid or the free drug.
Language	English
Publishing date	2023-01-26
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2527217-2
ISSN	1999-4923
ISSN	1999-4923
DOI	10.3390/pharmaceutics15020413
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Implantação de um programa de mentoria remoto para estudantes de Medicina em tempo de pandemia

Sandra Regina Gonzaga Mazutti / Ana Cristina Kuhn Pletsch Roncati / Délio Eulálio Martins

Revista Brasileira de Educação Médica, Vol 45, Iss suppl

2021 Volume 1

Abstract: Resumo: Introdução: Programas de mentoria são necessários para apoio ao estudante de Medicina e podem ter diversos objetivos, dependendo das instituições que os implementam, embora ainda não sejam uma realidade na maioria das universidades. Durante a ... ...

Abstract	Resumo: Introdução: Programas de mentoria são necessários para apoio ao estudante de Medicina e podem ter diversos objetivos, dependendo das instituições que os implementam, embora ainda não sejam uma realidade na maioria das universidades. Durante a pandemia da Covid-19, encontros presenciais foram impedidos, o que dificultou ainda mais a manutenção desses programas, apesar de ser um dos momentos de maior necessidade emocional para os alunos. Ajustaram-se as aulas, e os encontros foram transformados em remotos, e, dessa forma, a mentoria on-line passou a ser uma realidade. Relato de experiência: Apoiado pelo Núcleo de Apoio Psicopedagógico dos Estudantes de Medicina (Napem), foi estruturado um programa de mentoria em pequenos grupos, formados por docentes, discentes mais experientes (comentores) e mentorados (alunos do primeiro ao terceiro ano) com reuniões realizadas de forma remota, o que permitiu a participação dos estudantes, a interação com eles e o acolhimento desse público. As reuniões aconteceram entre junho e dezembro de 2020. O programa contou com a participação de 13 mentores, 94 alunos mentorados e 24 comentores. O programa teve uma sessão de treinamento com mentores e comentores, que foi conduzida pela psicóloga do Napem para alinhamento de expectativas e orientações. As discussões nos grupos focaram dificuldades na vida acadêmica, profissional e pessoal. Discussão: O modelo remoto de mentoria apresenta como pontos fortes a maior flexibilidade para mentores e mentorados, a facilidade de participação de ambos e a manutenção da conexão do grupo, pois os encontros são facilitados pela tecnologia, visto que não houve nenhuma desistência. Como ponto fraco dessa experiência, citamos a falta de análises quantitativas e qualitativas do programa utilizando, por exemplo, entrevistas ou questionários de forma científica para avaliar melhor os resultados. Conclusão: A mentoria remota é útil e deve ser incluída como uma possibilidade de legado permanente para os cursos de Medicina, pois os encontros ...
Keywords	Mentores ; Educação Médica ; Tutoria ; Pandemia ; Education (General) ; L7-991 ; Medicine (General) ; R5-920
Language	Portuguese
Publishing date	2021-06-01T00:00:00Z
Publisher	Associção Brasileira de Educação Médica
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Multifaceted Roles of microRNAs in Host-Bacterial Pathogen Interaction.

Aguilar, Carmen / Mano, Miguel / Eulalio, Ana

Microbiology spectrum

2019 Volume 7, Issue 3

Abstract: MicroRNAs (miRNAs) are a well-characterized class of small noncoding RNAs that act as major posttranscriptional regulators of gene expression. Accordingly, miRNAs have been associated with a wide range of fundamental biological processes and implicated ... ...

Abstract	MicroRNAs (miRNAs) are a well-characterized class of small noncoding RNAs that act as major posttranscriptional regulators of gene expression. Accordingly, miRNAs have been associated with a wide range of fundamental biological processes and implicated in human diseases. During the past decade, miRNAs have also been recognized for their role in the complex interplay between the host and bacterial pathogens, either as part of the host response to counteract infection or as a molecular strategy employed by bacteria to subvert host pathways for their own benefit. Importantly, the characterization of downstream miRNA targets and their underlying mechanisms of action has uncovered novel molecular factors and pathways relevant to infection. In this article, we review the current knowledge of the miRNA response to bacterial infection, focusing on different bacterial pathogens, including
MeSH term(s)	Animals ; Bacteria/pathogenicity ; Bacterial Infections/metabolism ; Bacterial Physiological Phenomena ; Gene Expression Regulation ; Helicobacter pylori ; Host-Pathogen Interactions/genetics ; Host-Pathogen Interactions/physiology ; Humans ; Listeria monocytogenes ; MicroRNAs/genetics ; MicroRNAs/physiology ; Mycobacterium ; Salmonella enterica
Chemical Substances	MicroRNAs
Language	English
Publishing date	2019-06-17
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Review
ISSN	2165-0497
ISSN (online)	2165-0497
DOI	10.1128/microbiolspec.BAI-0002-2019
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Dysregulated endolysosomal trafficking in cells arrested in the G

Lisowski, Clivia / Dias, Jane / Costa, Susana / Silva, Ricardo Jorge / Mano, Miguel / Eulalio, Ana

Autophagy

2021 Volume 18, Issue 8, Page(s) 1785–1800

Abstract: Modulation of the host cell cycle has emerged as a common theme among the pathways regulated by bacterial pathogens, arguably to promote host cell colonization. However, in most cases the exact benefit ensuing from such interference to the infection ... ...

Abstract	Modulation of the host cell cycle has emerged as a common theme among the pathways regulated by bacterial pathogens, arguably to promote host cell colonization. However, in most cases the exact benefit ensuing from such interference to the infection process remains unclear. Previously, we have shown that
MeSH term(s)	Autophagy ; Bacterial Proteins/metabolism ; Cell Cycle ; Lysosomes/metabolism ; Salmonella/metabolism ; Type III Secretion Systems/metabolism ; Vacuoles/metabolism
Chemical Substances	Bacterial Proteins ; Type III Secretion Systems
Language	English
Publishing date	2021-11-15
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2454135-7
ISSN	1554-8635 ; 1554-8627
ISSN (online)	1554-8635
ISSN	1554-8627
DOI	10.1080/15548627.2021.1999561
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 6741: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Project and Implementation of an Educational Large-Scale Water Distillation Unit with a Closed-Circuit Condenser

Luís Carlos Matos / Ana Eulálio / Tiago Antunes / José Miguel Loureiro / Alexandre Ferreira / Adélio Mendes

Sustainability, Vol 12, Iss 3239, p

2020 Volume 3239

Abstract: Water is one of the scarcest resources in the world, and it is becoming rarer fast, year after year. Chemical engineers are particularly suited to addressing the challenges of saving water and producing more fresh water. Proper education is then critical ...

Abstract	Water is one of the scarcest resources in the world, and it is becoming rarer fast, year after year. Chemical engineers are particularly suited to addressing the challenges of saving water and producing more fresh water. Proper education is then critical to prepare them for the upcoming decades. All student laboratories need distilled water, which is typically produced using commercial distillation units, which consume up to 70 L of fresh water per liter of distillated water. This work reports the design, construction, optimization, and operation of a water distillation unit that produces 10 liters per hour at 4 µS∙cm −1 and wastes no fresh water. Developed by a committed team made up of students, lab technicians, and instructors, this unit saves ca. 550 m 3 of fresh water annually while spending less electrical power.
Keywords	distilled water ; heat transfer ; distillation ; automation and control ; chemical engineering education ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
Subject code	333 ; 690
Language	English
Publishing date	2020-04-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: MicroRNAs at the Host-Bacteria Interface: Host Defense or Bacterial Offense.

Aguilar, Carmen / Mano, Miguel / Eulalio, Ana

Trends in microbiology

2018 Volume 27, Issue 3, Page(s) 206–218

Abstract: MicroRNAs are a class of small noncoding RNAs that act as major post-transcriptional regulators of gene expression. They are currently recognized for their important role in the intricate interaction between host and bacterial pathogens, either as part ... ...

Abstract	MicroRNAs are a class of small noncoding RNAs that act as major post-transcriptional regulators of gene expression. They are currently recognized for their important role in the intricate interaction between host and bacterial pathogens, either as part of the host immune response to neutralize infection, or as a molecular strategy employed by bacteria to hijack host pathways for their own benefit. Here, we summarize recent advances on the function of miRNAs during infection of mammalian hosts by bacterial pathogens, highlighting key cellular pathways. In addition, we discuss emerging themes in this field, including the participation of miRNAs in host-microbiota crosstalk and cell-to-cell communication.
MeSH term(s)	Animals ; Bacteria/genetics ; Bacteria/immunology ; Bacteria/pathogenicity ; Bacterial Infections/immunology ; Gastrointestinal Microbiome ; Gene Expression Regulation ; Host-Pathogen Interactions/genetics ; Host-Pathogen Interactions/immunology ; Humans ; MicroRNAs/genetics
Chemical Substances	MicroRNAs
Language	English
Publishing date	2018-11-23
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Review
ZDB-ID	1158963-2
ISSN	1878-4380 ; 0966-842X
ISSN (online)	1878-4380
ISSN	0966-842X
DOI	10.1016/j.tim.2018.10.011
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 3738: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: MicroRNA Screening and the Quest for Biologically Relevant Targets.

Eulalio, Ana / Mano, Miguel

Journal of biomolecular screening

2015 Volume 20, Issue 8, Page(s) 1003–1017

Abstract: MicroRNAs (miRNAs) are a class of genome-encoded small RNAs that post-transcriptionally regulate gene expression by repressing target transcripts containing partially or fully complementary binding sites.Despite their relatively low number, miRNAs have ... ...

Abstract	MicroRNAs (miRNAs) are a class of genome-encoded small RNAs that post-transcriptionally regulate gene expression by repressing target transcripts containing partially or fully complementary binding sites.Despite their relatively low number, miRNAs have been shown to directly regulate a large fraction of the transcriptome. In agreement with their pervasive role in the regulation of eukaryotic gene expression, miRNAs have been implicated in virtually all biological processes, including different pathologies.The use of screening technologies to systematically analyze miRNA function in cell-based assays offers a unique opportunity to gain new insights into complex biological and disease-relevant processes. Given the low complexity of the miRNome and the similarities to small interfering RNA (siRNA) screening experimental approaches, phenotypic screening using genome-wide libraries of miRNA mimics or inhibitors is not, per se, technically challenging. The identification of miRNA targets and, more importantly, the characterization of their mechanisms of action through the identification of the key targets underlying observed phenotypes remain the major challenges of this approach.This article provides an overview of cell-based screenings for miRNA function that were performed in different biological contexts. The advantages and limitations of computational and experimental approaches commonly used to identify miRNA targets are also discussed.
MeSH term(s)	Animals ; Cell Line ; Computational Biology/methods ; Genomics/methods ; High-Throughput Screening Assays ; Humans ; MicroRNAs/genetics ; RNA Interference ; RNA, Messenger/genetics ; Reproducibility of Results
Chemical Substances	MicroRNAs ; RNA, Messenger
Language	English
Publishing date	2015-09
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Review
ZDB-ID	1433680-7
ISSN	1552-454X ; 1087-0571
ISSN (online)	1552-454X
ISSN	1087-0571
DOI	10.1177/1087057115578837
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 4911: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: The induction of natural competence adapts staphylococcal metabolism to infection.

Cordero, Mar / García-Fernández, Julia / Acosta, Ivan C / Yepes, Ana / Avendano-Ortiz, Jose / Lisowski, Clivia / Oesterreicht, Babett / Ohlsen, Knut / Lopez-Collazo, Eduardo / Förstner, Konrad U / Eulalio, Ana / Lopez, Daniel

Nature communications

2022 Volume 13, Issue 1, Page(s) 1525

Abstract: A central question concerning natural competence is why orthologs of competence genes are conserved in non-competent bacterial species, suggesting they have a role other than in transformation. Here we show that competence induction in the human pathogen ...

Abstract	A central question concerning natural competence is why orthologs of competence genes are conserved in non-competent bacterial species, suggesting they have a role other than in transformation. Here we show that competence induction in the human pathogen Staphylococcus aureus occurs in response to ROS and host defenses that compromise bacterial respiration during infection. Bacteria cope with reduced respiration by obtaining energy through fermentation instead. Since fermentation is energetically less efficient than respiration, the energy supply must be assured by increasing the glycolytic flux. The induction of natural competence increases the rate of glycolysis in bacteria that are unable to respire via upregulation of DNA- and glucose-uptake systems. A competent-defective mutant showed no such increase in glycolysis, which negatively affects its survival in both mouse and Galleria infection models. Natural competence foster genetic variability and provides S. aureus with additional nutritional and metabolic possibilities, allowing it to proliferate during infection.
MeSH term(s)	Animals ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Carbohydrate Metabolism ; Fermentation ; Glycolysis/genetics ; Mice ; Staphylococcal Infections/microbiology ; Staphylococcus aureus/genetics ; Staphylococcus aureus/metabolism
Chemical Substances	Bacterial Proteins
Language	English
Publishing date	2022-03-21
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2553671-0
ISSN	2041-1723 ; 2041-1723
ISSN (online)	2041-1723
ISSN	2041-1723
DOI	10.1038/s41467-022-29206-7
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

To top

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito