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Article ; Online: Apolipoprotein C3 and apolipoprotein B colocalize in proximity to macrophages in atherosclerotic lesions in diabetes.

Kanter, Jenny E / Bornfeldt, Karin E

2020 Volume 62, Page(s) 100010

MeSH term(s)	Apolipoprotein C-III
Chemical Substances	Apolipoprotein C-III
Language	English
Publishing date	2020-12-13
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	80154-9
ISSN	1539-7262 ; 0022-2275
ISSN (online)	1539-7262
ISSN	0022-2275
DOI	10.1194/jlr.ILR120001217
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Article ; Online: Haemophilus influenzae type B in an immunocompetent, fully vaccinated ALL survivor.

Nevin, John / Kanter Washko, Julie / Arnold, John

Pediatrics

2013 Volume 131, Issue 5, Page(s) e1639–42

Abstract: ... as Haemophilus influenzae type b, β-lactamase negative. Review of the patient's medical records showed a history of complete ... immunization to Haemophilus influenzae type b. An immunologic evaluation was made to determine if the patient ... or hepatitis B. This loss of immunologic memory appears to be a rarely described side effect ...

Abstract	A 7-year-old boy with a history of recurrent acute lymphoblastic leukemia (ALL), in remission, presented to primary care clinic after 2 days of progressive right hip pain with weight-bearing activities. He was otherwise asymptomatic at the time of presentation. Blood cultures revealed Gram-negative diplococci, which prompted an MRI that was significant for a hip joint effusion and femoral head bone marrow edema. The patient had no sick contacts and no significant past medical history other than ALL. The patient had been given all recommended childhood vaccinations. Arthrocentesis and needle biopsy of the femoral neck were not diagnostic for malignancy and revealed only mild hip joint inflammation, leading to a diagnosis of osteomyelitis. The organism in the original blood culture was identified as Haemophilus influenzae type b, β-lactamase negative. Review of the patient's medical records showed a history of complete immunization to Haemophilus influenzae type b. An immunologic evaluation was made to determine if the patient retained immunity from his other vaccinations. Pathogen-specific antibody testing revealed detectable antibodies to polio but not measles, mumps, rubella, varicella-zoster virus, tetanus, diphtheria, pertussis, or hepatitis B. This loss of immunologic memory appears to be a rarely described side effect of ALL chemotherapy. There is currently no protocol to evaluate the immunologic memory of patients who underwent chemotherapy for ALL or to revaccinate them after their treatment. It is unclear whether the loss of immunologic memory is genuinely rare or is underdiagnosed because affected patients are protected by herd immunity.
MeSH term(s)	Antineoplastic Combined Chemotherapy Protocols/administration & dosage ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Arthralgia/physiopathology ; Blood/microbiology ; Child ; Follow-Up Studies ; Haemophilus Infections/diagnosis ; Haemophilus Infections/immunology ; Haemophilus Infections/prevention & control ; Haemophilus Vaccines/administration & dosage ; Haemophilus Vaccines/immunology ; Haemophilus influenzae type b/immunology ; Hip Joint/diagnostic imaging ; Hip Joint/physiopathology ; Humans ; Immunization, Secondary/methods ; Immunocompetence/immunology ; Immunologic Memory/drug effects ; Immunologic Memory/immunology ; Male ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/diagnosis ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/drug therapy ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/immunology ; Radiography ; Risk Assessment ; Survivors ; Vaccination/methods
Chemical Substances	Haemophilus Vaccines
Language	English
Publishing date	2013-05
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	207677-9
ISSN	1098-4275 ; 0031-4005
ISSN (online)	1098-4275
ISSN	0031-4005
DOI	10.1542/peds.2012-1126
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Zs.MO 357: Show issues

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Article: Modern communications technology: An essential tool for optimizing hospital operations and improving outcomes.

Kanter, Benjamin

Healthcare management forum

2021 Volume 34, Issue 5, Page(s) 248–251

Abstract: An ability to rapidly convert data from multiple different sources into actionable information is embodied in a concept called Real-time Health Systems (RTHS). The foundational component of RTHS is a modern Clinical Communication and Collaboration (CC&C) ...

Abstract	An ability to rapidly convert data from multiple different sources into actionable information is embodied in a concept called Real-time Health Systems (RTHS). The foundational component of RTHS is a modern Clinical Communication and Collaboration (CC&C) Platform, which translates organizational knowledge into action. Effective communication is the key. A CC&C Platform that can receive data from multiple hospital systems, analyze the data, arbitrate any resulting actions and determine the relative priorities to distribute work to the right person or teams-can lead to improved operational efficiencies and better patient outcomes.
MeSH term(s)	Communication ; Hospitals ; Humans
Language	English
Publishing date	2021-08-14
Publishing country	United States
Document type	Journal Article
ZDB-ID	2140831-2
ISSN	2352-3883 ; 0840-4704
ISSN (online)	2352-3883
ISSN	0840-4704
DOI	10.1177/08404704211038215
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Zs.A 5895: Show issues

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Article ; Online: Double aortic arch with aortic atresia and left-sided type B interruption.

Baker-Smith, Carissa M / Milazzo, Angelo S / Frush, Donald P / Jaggers, James / Kirby, Margaret L / Kanter, Ronald J / Barker, Piers C

Congenital heart disease

2010 Volume 5, Issue 3, Page(s) 316–320

Abstract: ... of our knowledge, the first case of a live birth with aortic valve atresia and interrupted left aortic arch (type B ...

Abstract	Aortic valve atresia with interruption of the aortic arch is an extremely rare anomaly; only eleven cases of this anomaly have been reported to date. In the absence of additional sources of blood flow to the ascending aorta, aortic valve atresia with interruption of the aortic arch is fatal. We present, to the best of our knowledge, the first case of a live birth with aortic valve atresia and interrupted left aortic arch (type B) without evidence of an aorticopulmonary communication or ductal supply to the native ascending aorta. Instead, blood flow to the native aortic root was derived from a persistent right embryonic dorsal aorta.
MeSH term(s)	Abnormalities, Multiple/diagnosis ; Abnormalities, Multiple/physiopathology ; Abnormalities, Multiple/surgery ; Aorta, Thoracic/abnormalities ; Aorta, Thoracic/physiopathology ; Aorta, Thoracic/surgery ; Aortic Valve/abnormalities ; Aortic Valve/physiopathology ; Aortic Valve/surgery ; Cardiac Surgical Procedures/adverse effects ; Fatal Outcome ; Heart Defects, Congenital/diagnosis ; Heart Defects, Congenital/physiopathology ; Heart Defects, Congenital/surgery ; Hemodynamics ; Humans ; Live Birth ; Tomography, X-Ray Computed ; Treatment Outcome ; Vascular Malformations/diagnosis ; Vascular Malformations/physiopathology ; Vascular Malformations/surgery
Language	English
Publishing date	2010-05
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	2274321-2
ISSN	1747-0803 ; 1747-079X
ISSN (online)	1747-0803
ISSN	1747-079X
DOI	10.1111/j.1747-0803.2009.00341.x
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Zs.A 6693: Show issues

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Article: Rapid expression of vaccine proteins for B-cell lymphoma in a cell-free system.

Yang, Junhao / Kanter, Gregory / Voloshin, Alexei / Michel-Reydellet, Nathalie / Velkeen, Hendrik / Levy, Ronald / Swartz, James R

Biotechnology and bioengineering

2005 Volume 89, Issue 5, Page(s) 503–511

Abstract: ... potential vaccines for immunotherapy of B-cell lymphoma. In this study, four vaccine candidates were ... constructed by fusing murine GM-CSF to the amino- or carboxy-terminus of the 38C13 murine B-lymphocyte Id scFv ... incorrectly formed disulfide linkages. The 38C13 B-lymphocyte Id scFv was expressed with 30% of its soluble ...

Abstract	The idiotype (Id)-granulocyte-macrophage colony-stimulating factor (GM-CSF) fusion proteins are potential vaccines for immunotherapy of B-cell lymphoma. In this study, four vaccine candidates were constructed by fusing murine GM-CSF to the amino- or carboxy-terminus of the 38C13 murine B-lymphocyte Id scFv with two different arrangements of the variable regions of the heavy chain and light chain (VL-VH and VH-VL). scFv (VH-VL) and GM-CSF/scFv fusion proteins were expressed in an Escherichia coli cell-free protein synthesis system. In order to promote disulfide bond formation during cell-free expression, cell extract was pretreated with iodoacetamide (IAM), and a sulfhydryl redox buffer composed of oxidized and reduced glutathione was added. The E. coli periplasmic disulfide isomerase, DsbC, was also added to rearrange incorrectly formed disulfide linkages. The 38C13 B-lymphocyte Id scFv was expressed with 30% of its soluble yield in active form (43 microg/ml) when tested with an anti-idiotypic mAb, S1C5, as the capture antibody in radioimmunoassay. It was found that the amino-terminal GM-CSF fusion proteins, GM-VL-VH and GM-VH-VL, showed much higher activity than the carboxy-terminal GM-CSF fusion proteins, VL-VH-GM and VH-VL-GM, in stimulating the cell proliferation of a GM-CSF-dependent cell line, NFS-60. Between the two amino-terminal GM-CSF fusion proteins, GM-VL-VH showed a higher total and soluble yield than GM-VH-VL.
MeSH term(s)	Animals ; Antibodies, Monoclonal/metabolism ; Autoradiography ; Cancer Vaccines/immunology ; Cell Proliferation ; Cell-Free System ; Disulfides/chemistry ; Escherichia coli/enzymology ; Escherichia coli/genetics ; Gene Expression Regulation, Bacterial ; Granulocyte-Macrophage Colony-Stimulating Factor/chemistry ; Granulocyte-Macrophage Colony-Stimulating Factor/genetics ; Granulocyte-Macrophage Colony-Stimulating Factor/metabolism ; Immunoglobulin Heavy Chains ; Immunoglobulin Idiotypes ; Immunoglobulin Light Chains ; Immunoglobulin Variable Region ; Lymphoma, B-Cell/therapy ; Mice ; Protein Disulfide-Isomerases/metabolism ; Protein Folding ; Protein Structure, Tertiary ; Proteins/metabolism ; Recombinant Fusion Proteins/chemistry ; Recombinant Fusion Proteins/metabolism ; Vaccines/chemistry ; Vaccines/genetics ; Vaccines/immunology
Chemical Substances	Antibodies, Monoclonal ; Cancer Vaccines ; Disulfides ; Immunoglobulin Heavy Chains ; Immunoglobulin Idiotypes ; Immunoglobulin Light Chains ; Immunoglobulin Variable Region ; Proteins ; Recombinant Fusion Proteins ; Vaccines ; Granulocyte-Macrophage Colony-Stimulating Factor (83869-56-1) ; Protein Disulfide-Isomerases (EC 5.3.4.1)
Language	English
Publishing date	2005-03-05
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, U.S. Gov't, P.H.S.
ZDB-ID	280318-5
ISSN	1097-0290 ; 0006-3592
ISSN (online)	1097-0290
ISSN	0006-3592
DOI	10.1002/bit.20283
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Zs.B 960: Show issues

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Article ; Online: Bupropion: Does Its Efficacy Outweigh Potential Morbidity and Lethality?

Al-Namnakani, Bayan / Zell-Kanter, Michele

Pediatric annals

2023 Volume 52, Issue 5, Page(s) e178–e179

Abstract: Bupropion is a structurally and biochemically unique antidepressant that inhibits the neuronal uptake of dopamine and norepinephrine. Often prescribed for children and adolescents, bupropion displays both neurologic and cardiac toxicities in overdose ... ...

Abstract	Bupropion is a structurally and biochemically unique antidepressant that inhibits the neuronal uptake of dopamine and norepinephrine. Often prescribed for children and adolescents, bupropion displays both neurologic and cardiac toxicities in overdose more serious than toxicities resulting from poisonings by tricyclic antidepressants and selective serotonin reuptake inhibitors. Bupropion was briefly removed from the market in the 1980s. The incidence of bupropion poisonings in the United States, and resultant morbidity and mortality in children and adolescents, has been steadily increasing since 2012. Antidepressants less toxic than bupropion in overdose should be considered in the vulnerable 6- to 19-year-old patient population.
MeSH term(s)	Adolescent ; Child ; Humans ; Young Adult ; Adult ; Bupropion/adverse effects ; Morbidity ; Dopamine ; Norepinephrine ; Selective Serotonin Reuptake Inhibitors
Chemical Substances	Bupropion (01ZG3TPX31) ; Dopamine (VTD58H1Z2X) ; Norepinephrine (X4W3ENH1CV) ; Selective Serotonin Reuptake Inhibitors
Language	English
Publishing date	2023-05-01
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	195430-1
ISSN	1938-2359 ; 0090-4481
ISSN (online)	1938-2359
ISSN	0090-4481
DOI	10.3928/19382359-20230307-01
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Zs.A 1347: Show issues

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Article ; Online: Relational concerns and change in relationship satisfaction in a relationship education program.

Kanter, Jeremy B / Lannin, Daniel G / Rauer, Amy J / Yazedjian, Ani

Family process

2023 Volume 62, Issue 2, Page(s) 576–590

Abstract: Lower income couples tend to report more difficulty sustaining high-quality intimate relationships. As a result, policy initiatives have been enacted to fund relationship education (RE) programs that aim to increase lower income couples' relationship ... ...

Abstract	Lower income couples tend to report more difficulty sustaining high-quality intimate relationships. As a result, policy initiatives have been enacted to fund relationship education (RE) programs that aim to increase lower income couples' relationship satisfaction. Generally, these programs demonstrate small, albeit statistically significant improvements in mean levels of relationship functioning. It is critical, however, to understand if RE programming influences the developmental course of intimate relationships, and if this influence depends on couples' initial levels of concerns about their relationships. Using dyadic group-based modeling and three waves of data from 6034 couples in the Supporting Healthy Marriages project, a randomized control trial of RE, we categorized couples into four relationship concern groups (No Relational Concerns, Both Relationally Concerned, Men's Relational Concerns, and Women's Relational Concerns) and explored how these groups moderated the long-term efficacy of RE programming. Results indicated that RE was associated with different developmental trajectories of satisfaction, but RE effects differed for men and women. Specifically, random assignment into RE was associated with men maintaining high levels of relationship satisfaction, whereas women's satisfaction decreased over time. These effects were not moderated by initial relationship concerns. The association between RE and relationship satisfaction trajectories was small in magnitude, suggesting that more comprehensive services are needed to strengthen lower income couples' intimate relationships.
MeSH term(s)	Male ; Humans ; Female ; Sexual Behavior ; Sexual Partners ; Personal Satisfaction ; Poverty ; Educational Status
Language	English
Publishing date	2023-02-15
Publishing country	United States
Document type	Randomized Controlled Trial ; Journal Article ; Research Support, U.S. Gov't, P.H.S.
ZDB-ID	212740-4
ISSN	1545-5300 ; 0014-7370
ISSN (online)	1545-5300
ISSN	0014-7370
DOI	10.1111/famp.12851
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Article ; Online: How do you Behave as a Psychometrician? Research Conduct in the Context of Psychometric Research.

Flores-Kanter, Pablo Ezequiel / Mosquera, Mariano

The Spanish journal of psychology

2023 Volume 26, Page(s) e13

Abstract: ... specifically linked to psychometric studies; and (b) promoting greater awareness and widespread application ...

Abstract	The identification of fraudulent and questionable research conduct is not something new. However, in the last 12 years the aim has been to identify specific problems and concrete solutions applicable to each area of knowledge. For example, previous work has focused on questionable and responsible research conducts associated with clinical assessment, measurement practices in psychology and related sciences; or applicable to specific areas of study, such as suicidology. One area of study that merits further study of questionable and responsible research behaviors is psychometrics. Focusing on psychometric research is important and necessary, as without adequate evidence of construct validity the overall validity of the research is at least debatable. Our interest here is to (a) identifying questionable research conduct specifically linked to psychometric studies; and (b) promoting greater awareness and widespread application of responsible research conduct in psychometrics research. We believe that the identification and recognition of these conducts is important and will help us to improve our daily work as psychometricians.
MeSH term(s)	Humans ; Psychometrics ; Reproducibility of Results
Language	English
Publishing date	2023-05-17
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	2073783-X
ISSN	1988-2904 ; 1138-7416
ISSN (online)	1988-2904
ISSN	1138-7416
DOI	10.1017/SJP.2023.14
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Article ; Online: Atypical cervical radiculopathy presenting with brachioradial pruritus: illustrative cases.

Khalifeh, Kareem / Le, Janneinne / Musmar, Basel / Maroon, Joseph / Kanter, Adam S / Ozgur, Burak

Journal of neurosurgery. Case lessons

2024 Volume 7, Issue 8

Abstract: Background: Brachioradial pruritus (BRP) is a rare form of chronic dysesthesia characterized by persistent itching, burning, or tingling commonly involving the dorsolateral upper extremities. Although the exact pathophysiology remains unclear, the ... ...

Abstract	Background: Brachioradial pruritus (BRP) is a rare form of chronic dysesthesia characterized by persistent itching, burning, or tingling commonly involving the dorsolateral upper extremities. Although the exact pathophysiology remains unclear, the condition may be a manifestation of atypical cervical radiculopathy. Observations: The authors describe two patients with BRP, a 44-year-old female and a 51-year-old male, both of whom benefited from surgical intervention for atypical cervical radiculopathy, while also highlighting their presentation, diagnostic testing, treatment, and outcomes. Lessons: The cases demonstrate the potential relationship between cervical spondylosis and BRP while examining the role of surgical intervention as a treatment option.
Language	English
Publishing date	2024-02-19
Publishing country	United States
Document type	Journal Article
ISSN	2694-1902
ISSN (online)	2694-1902
DOI	10.3171/CASE23715
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Article ; Online: Understanding the Early Years of Socioeconomically Disadvantaged Couples' Marriages.

Kanter, Jeremy B / Proulx, Christine M

Family process

2020 Volume 60, Issue 3, Page(s) 806–822

Abstract: Recent research has identified significant differences in how satisfaction in newlywed relationships progress, with the majority of spouses reporting relatively high marital satisfaction. However, most studies have focused on white, middle class, ... ...

Abstract	Recent research has identified significant differences in how satisfaction in newlywed relationships progress, with the majority of spouses reporting relatively high marital satisfaction. However, most studies have focused on white, middle class, childless couples, and it is not clear whether these findings hold for socioeconomically disadvantaged couples (those with low educational attainment or income). Further, previous work has largely ignored differences between spouses within the same marriage and the circumstances under which interpersonal processes between spouses are influential to prospective marital satisfaction. Using dyadic growth-mixture modeling and three waves of data from 530 newlywed couples in the Supporting Healthy Marriages study, we simultaneously modeled husbands' and wives' marital satisfaction and identified two classes of couples, labeled the Relatively satisfied class and Husbands' moderate intercept, wives' low, and increasing satisfaction class. Husbands consistently reported better marital satisfaction than their wives regardless of class membership. Wives' perceptions of interpersonal processes during experiences of financial stress predicted class membership. Dissolution rates also differed between classes. We conclude by providing practical implications for working with socioeconomically disadvantaged families.
MeSH term(s)	Humans ; Income ; Marriage ; Personal Satisfaction ; Prospective Studies ; Spouses
Language	English
Publishing date	2020-10-21
Publishing country	United States
Document type	Journal Article
ZDB-ID	212740-4
ISSN	1545-5300 ; 0014-7370
ISSN (online)	1545-5300
ISSN	0014-7370
DOI	10.1111/famp.12602
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