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  1. Article: The Heavy Links between Geological Events and Vascular Plants Evolution: A Brief Outline.

    Piombino, Aldo

    International journal of evolutionary biology

    2016  Volume 2016, Page(s) 9264357

    Abstract: Since the rise of photosynthesis, life has influenced terrestrial atmosphere, particularly the O2 and the CO2 content (the latter being originally more than 95%), changing the chemistry of waters, atmosphere, and soils. Billions of years after, a far ... ...

    Abstract Since the rise of photosynthesis, life has influenced terrestrial atmosphere, particularly the O2 and the CO2 content (the latter being originally more than 95%), changing the chemistry of waters, atmosphere, and soils. Billions of years after, a far offspring of these first unicellular forms conquered emerging lands, not only completely changing landscape, but also modifying geological cycles of deposition and erosion, many chemical and physical characteristics of soils and fresh waters, and, more, the cycle of various elements. So, there are no doubts that vascular plants modified geology; but it is true that also geology has affected (and, more, has driven) plant evolution. New software, PyRate, has determined vascular plant origin and diversification through a Bayesian analysis of fossil record from Silurian to today, particularly observing their origination and extinction rate. A comparison between PyRate data and geological history suggests that geological events massively influenced plant evolution and that also the rise of nonflowering seed plants and the fast diffusion of flowering plants can be explained, almost partly, with the environmental condition changes induced by geological phenomena.
    Language English
    Publishing date 2016-02-04
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2090-8032
    ISSN 2090-8032
    DOI 10.1155/2016/9264357
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  2. Article ; Online: Fusion of GNSS and Satellite Radar Interferometry

    Gregorio Farolfi / Aldo Piombino / Filippo Catani

    Remote Sensing, Vol 11, Iss 4, p

    Determination of 3D Fine-Scale Map of Present-Day Surface Displacements in Italy as Expressions of Geodynamic Processes

    2019  Volume 394

    Abstract: We present a detailed map of ground movement in Italy derived from the combination of the Global Navigation Satellite System (GNSS) and Satellite Synthetic Aperture Radar (SAR) interferometry. These techniques are two of the most used space geodetic ... ...

    Abstract We present a detailed map of ground movement in Italy derived from the combination of the Global Navigation Satellite System (GNSS) and Satellite Synthetic Aperture Radar (SAR) interferometry. These techniques are two of the most used space geodetic techniques to study Earth surface deformation. The above techniques provide displacements with respect to different components of the ground point position; GNSSs use the geocentric International Terrestrial Reference System 1989 (ITRS89), whereas the satellite SAR interferometry components are identified by the Lines of Sight (LOSs) between a satellite and ground points. Moreover, SAR interferometry is a differential technique, and for that reason, displacements have no absolute reference datum. We performed datum alignment of InSAR products using precise velocity fields derived from GNSS permanent stations. The result is a coherent ground velocity field with detailed boundaries of velocity patterns that provide new information about the complex geodynamics involved on the Italian peninsula and about local movements.
    Keywords geodesy ; geodynamics ; GNSS ; SAR ; DInSAR ; Persistent Scatter Interferometry ; calibration ; Science ; Q
    Subject code 600
    Language English
    Publishing date 2019-02-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Surgical management of pleomorphic adenoma of parotid gland in elderly patients: role of morphological features.

    Guerra, Germano / Testa, Domenico / Montagnani, Stefania / Tafuri, Domenico / Salzano, Francesco Antonio / Rocca, Aldo / Amato, Bruno / Salzano, Giovanni / Dell'Aversana Orabona, Giovanni / Piombino, Pasquale / Motta, Gaetano

    International journal of surgery (London, England)

    2014  Volume 12 Suppl 2, Page(s) S12–S16

    Abstract: The neoplasms of the salivary glands account for 2% of head and neck tumors and the most common form is the Pleomorphic adenoma (PA). Parotid gland is affected from 80% to 90% of cases. In elderly these tumors occur mostly in females. These benign tumors ...

    Abstract The neoplasms of the salivary glands account for 2% of head and neck tumors and the most common form is the Pleomorphic adenoma (PA). Parotid gland is affected from 80% to 90% of cases. In elderly these tumors occur mostly in females. These benign tumors are composed of epithelial and myoepithelial cells that are arranged with various morphological patterns and subtypes. The classification of these tumors is also based on the amount and nature of the stroma. In literature there is an almost complete consensus that, in the major salivary glands, PAs are enclosed by a layer of fibrous tissue often called "capsule" but there is disagreement about the form, extension and thickness of this layer. The treatment is surgical and there are two main different surgical approaches: an enucleation (local dissection) or so-called subtotal superficial parotidectomy and lateral or superficial total parotidectomy. Histopathological characteristics of PAs especially of capsular alterations such as thin capsule areas, capsule-free regions, capsule penetration, satellite nodules and pseudopodia in the different subtypes are important for the choice of surgical treatment and the first explanation for tumor recurrence. In our study we describe a morphological features of 84 cases of pleomorphic adenoma of parotid gland from elderly patients treated by a surgical "enucleation like" method called nucleoresection.
    MeSH term(s) Adenoma, Pleomorphic/pathology ; Adenoma, Pleomorphic/surgery ; Aged ; Disease-Free Survival ; Female ; Humans ; Image Processing, Computer-Assisted ; Male ; Neoplasm Recurrence, Local/pathology ; Parotid Neoplasms/pathology ; Parotid Neoplasms/surgery
    Language English
    Publishing date 2014
    Publishing country England
    Document type Journal Article
    ZDB-ID 2212038-5
    ISSN 1743-9159 ; 1743-9191
    ISSN (online) 1743-9159
    ISSN 1743-9191
    DOI 10.1016/j.ijsu.2014.08.391
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  4. Article ; Online: Prospective clinical evaluation of 201 direct laser metal forming implants: results from a 1-year multicenter study.

    Mangano, Carlo / Mangano, Francesco / Shibli, Jamil Awad / Luongo, Giuseppe / De Franco, Michele / Briguglio, Francesco / Figliuzzi, Michele / Eccellente, Tammaro / Rapani, Carmine / Piombino, Michele / Macchi, Aldo

    Lasers in medical science

    2011  Volume 27, Issue 1, Page(s) 181–189

    Abstract: This prospective clinical study evaluated the survival rate and the implant-crown success of 201 direct laser metal forming (DLMF) implants in different clinical applications, after short-term follow-up of functional loading. At the 1-year scheduled ... ...

    Abstract This prospective clinical study evaluated the survival rate and the implant-crown success of 201 direct laser metal forming (DLMF) implants in different clinical applications, after short-term follow-up of functional loading. At the 1-year scheduled follow-up examination, several clinical, radiographic, and prosthetic parameters were assessed. Success criteria included absence of pain, sensitivity, suppuration, exudation; absence of implant mobility; absence of continuous peri-implant radiolucency, DIB <1.5 mm; absence of prosthetic complications at the implant-abutment interface. A total of 201 implants (106 maxilla, 95 mandible) were inserted in 62 patients (39 males, 23 females; aged between 26 and 65 years) in eight different clinical centers. The sites included anterior (n = 79) and posterior (n = 122) implants. The overall implant survival rate was 99.5%, with one implant loss (maxilla: 99.0%, 1 implant failure; mandible: 100.0%, no implant failures). The mean DIB was 0.4 ± 0.2 mm. Among the survived implants (200), five did not fulfill the success criteria, giving an implant-crown success of 97.5%. This 1-year follow-up prospective clinical study gives evidence of very high survival (99.5%) and success (97.5%) rates using DLMF implants.
    MeSH term(s) Adult ; Aged ; Crowns ; Dental Implants/adverse effects ; Dental Prosthesis Design ; Dental Prosthesis, Implant-Supported ; Dental Restoration Failure ; Female ; Follow-Up Studies ; Humans ; Lasers ; Male ; Mandible/surgery ; Maxilla/surgery ; Middle Aged ; Prospective Studies
    Chemical Substances Dental Implants
    Language English
    Publishing date 2011-04-26
    Publishing country England
    Document type Clinical Trial ; Journal Article ; Multicenter Study
    ZDB-ID 632808-8
    ISSN 1435-604X ; 0268-8921
    ISSN (online) 1435-604X
    ISSN 0268-8921
    DOI 10.1007/s10103-011-0904-3
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  5. Article ; Online: Identification of optimal therapeutic window for steroid use in severe alcohol-associated hepatitis: A worldwide study.

    Arab, Juan Pablo / Díaz, Luis Antonio / Baeza, Natalia / Idalsoaga, Francisco / Fuentes-López, Eduardo / Arnold, Jorge / Ramírez, Carolina A / Morales-Arraez, Dalia / Ventura-Cots, Meritxell / Alvarado-Tapias, Edilmar / Zhang, Wei / Clark, Virginia / Simonetto, Douglas / Ahn, Joseph C / Buryska, Seth / Mehta, Tej I / Stefanescu, Horia / Horhat, Adelina / Bumbu, Andreea /
    Dunn, Winston / Attar, Bashar / Agrawal, Rohit / Haque, Zohaib Syed / Majeed, Muhammad / Cabezas, Joaquín / García-Carrera, Inés / Parker, Richard / Cuyàs, Berta / Poca, Maria / Soriano, German / Sarin, Shiv K / Maiwall, Rakhi / Jalal, Prasun K / Abdulsada, Saba / Higuera-de la Tijera, María Fátima / Kulkarni, Anand V / Rao, P Nagaraja / Guerra Salazar, Patricia / Skladaný, Lubomir / Bystrianska, Natália / Prado, Veronica / Clemente-Sanchez, Ana / Rincón, Diego / Haider, Tehseen / Chacko, Kristina R / Cairo, Fernando / de Sousa Coelho, Marcela / Romero, Gustavo A / Pollarsky, Florencia D / Restrepo, Juan Carlos / Castro-Sanchez, Susana / Toro, Luis G / Yaquich, Pamela / Mendizabal, Manuel / Garrido, Maria Laura / Narvaez, Adrián / Bessone, Fernando / Marcelo, Julio Santiago / Piombino, Diego / Dirchwolf, Melisa / Arancibia, Juan Pablo / Altamirano, José / Kim, Won / Araujo, Roberta C / Duarte-Rojo, Andrés / Vargas, Victor / Rautou, Pierre-Emmanuel / Issoufaly, Tazime / Zamarripa, Felipe / Torre, Aldo / Lucey, Michael R / Mathurin, Philippe / Louvet, Alexandre / García-Tsao, Guadalupe / González, José Alberto / Verna, Elizabeth / Brown, Robert S / Roblero, Juan Pablo / Abraldes, Juan G / Arrese, Marco / Shah, Vijay H / Kamath, Patrick S / Singal, Ashwani K / Bataller, Ramon

    Journal of hepatology

    2021  Volume 75, Issue 5, Page(s) 1026–1033

    Abstract: Background & aims: Corticosteroids are the only effective therapy for severe alcohol-associated hepatitis (AH), defined by a model for end-stage liver disease (MELD) score >20. However, there are patients who may be too sick to benefit from therapy. ... ...

    Abstract Background & aims: Corticosteroids are the only effective therapy for severe alcohol-associated hepatitis (AH), defined by a model for end-stage liver disease (MELD) score >20. However, there are patients who may be too sick to benefit from therapy. Herein, we aimed to identify the range of MELD scores within which steroids are effective for AH.
    Methods: We performed a retrospective, international multicenter cohort study across 4 continents, including 3,380 adults with a clinical and/or histological diagnosis of AH. The main outcome was mortality at 30 days. We used a discrete-time survival analysis model, and MELD cut-offs were established using the transform-the-endpoints method.
    Results: In our cohort, median age was 49 (40-56) years, 76.5% were male, and 79% had underlying cirrhosis. Median MELD at admission was 24 (19-29). Survival was 88% (87-89) at 30 days, 77% (76-78) at 90 days, and 72% (72-74) at 180 days. A total of 1,225 patients received corticosteroids. In an adjusted-survival-model, corticosteroid use decreased 30-day mortality by 41% (hazard ratio [HR] 0.59; 0.47-0.74; p <0.001). Steroids only improved survival in patients with MELD scores between 21 (HR 0.61; 0.39-0.95; p = 0.027) and 51 (HR 0.72; 0.52-0.99; p = 0.041). The maximum effect of corticosteroid treatment (21-30% survival benefit) was observed with MELD scores between 25 (HR 0.58; 0.42-0.77; p <0.001) and 39 (HR 0.57; 0.41-0.79; p <0.001). No corticosteroid benefit was seen in patients with MELD >51. The type of corticosteroids used (prednisone, prednisolone, or methylprednisolone) was not associated with survival benefit (p = 0.247).
    Conclusion: Corticosteroids improve 30-day survival only among patients with severe AH, especially with MELD scores between 25 and 39.
    Lay summary: Alcohol-associated hepatitis is a condition where the liver is severely inflamed as a result of excess alcohol use. It is associated with high mortality and it is not clear whether the most commonly used treatments (corticosteroids) are effective, particularly in patients with very severe liver disease. In this worldwide study, the use of corticosteroids was associated with increased 30-day, but not 90- or 180-day, survival. The maximal benefit was observed in patients with an MELD score (a marker of severity of liver disease; higher scores signify worse disease) between 25-39. However, this benefit was lost in patients with the most severe liver disease (MELD score higher than 51).
    MeSH term(s) Adult ; Alcohol Drinking/adverse effects ; Alcohol Drinking/drug therapy ; Alcohol Drinking/physiopathology ; Cohort Studies ; Female ; Hepatitis/drug therapy ; Hepatitis/etiology ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Severity of Illness Index ; Steroids/administration & dosage ; Steroids/therapeutic use ; Time Factors
    Chemical Substances Steroids
    Language English
    Publishing date 2021-06-21
    Publishing country Netherlands
    Document type Journal Article ; Observational Study ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 605953-3
    ISSN 1600-0641 ; 0168-8278
    ISSN (online) 1600-0641
    ISSN 0168-8278
    DOI 10.1016/j.jhep.2021.06.019
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