Article ; Online: Uncaria tomentosa
Journal of biomolecular structure & dynamics
2020 Volume 40, Issue 5, Page(s) 2227–2243
Abstract: COVID-19 is a novel severe acute respiratory syndrome coronavirus. Currently, there is no effective treatment and vaccines seem to be the solution in the future. Virtual screening of potential drugs against the S protein of severe acute respiratory ... ...
Abstract | COVID-19 is a novel severe acute respiratory syndrome coronavirus. Currently, there is no effective treatment and vaccines seem to be the solution in the future. Virtual screening of potential drugs against the S protein of severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) has provided small molecular compounds with a high binding affinity. Unfortunately, most of these drugs do not attach with the binding interface of the receptor-binding domain (RBD)-angiotensin-converting enzyme-2 (ACE-2) complex in host cells. Molecular modeling was carried out to evaluate the potential antiviral properties of the components of the medicinal herb |
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MeSH term(s) | COVID-19/drug therapy ; Cat's Claw/chemistry ; Herbal Medicine ; Humans ; Plant Extracts/chemistry ; Plant Extracts/pharmacology ; Plants, Medicinal ; SARS-CoV-2 ; Spike Glycoprotein, Coronavirus |
Chemical Substances | Plant Extracts ; Spike Glycoprotein, Coronavirus ; spike protein, SARS-CoV-2 |
Keywords | covid19 |
Language | English |
Publishing date | 2020-10-29 |
Publishing country | England |
Document type | Journal Article |
ZDB-ID | 49157-3 |
ISSN | 1538-0254 ; 0739-1102 |
ISSN (online) | 1538-0254 |
ISSN | 0739-1102 |
DOI | 10.1080/07391102.2020.1837676 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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