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Article ; Online: Re: Jim C. Hu, Melissa Assel, Mohamad E. Allaf, et al. Transrectal Magnetic Resonance Imaging-targeted and Systematic Prostate Biopsy to Prevent Infectious Complications: The PREVENT Randomized Trial. Eur Urol. In press. https://doi.org/10.1016/j.eururo.2023.12.015.

Marra, Giancarlo / Oderda, Marco / Gontero, Paolo

2024

Language	English
Publishing date	2024-03-25
Publishing country	Switzerland
Document type	Letter
ZDB-ID	193790-x
ISSN	1873-7560 ; 1421-993X ; 0302-2838
ISSN (online)	1873-7560 ; 1421-993X
ISSN	0302-2838
DOI	10.1016/j.eururo.2024.02.018
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Article ; Online: Inguinal Lymphadenectomy for Penile Cancer: An Interim Report from a Trial Comparing Open Versus Videoendoscopic Surgery Using a Within-patient Design.

Falcone, Marco / Gül, Murat / Peretti, Federica / Preto, Mirko / Cirigliano, Lorenzo / Scavone, Martina / Sedigh, Omid / Oderda, Marco / Gontero, Paolo

European urology open science

2024 Volume 63, Page(s) 31–37

Abstract: Background and objective: Nodal metastasis is a major survival and prognostic factor in penile cancer (PeCa). Thus, accurate staging, prognosis, and treatment selection require adequate inguinal lymphadenectomy (ILND). ILND surgery should balance ... ...

Abstract	Background and objective: Nodal metastasis is a major survival and prognostic factor in penile cancer (PeCa). Thus, accurate staging, prognosis, and treatment selection require adequate inguinal lymphadenectomy (ILND). ILND surgery should balance oncologic rigor with morbidity and postoperative complications. Our aim was to compare the feasibility and safety of open ILND (OILND) and videoendoscopic ILND (VEILND) in patients with PeCa. Methods: We conducted a single-center randomized trial with a within-patient design between October 2019 and April 2023. Patients who were undergoing either staging or radical ILND for PeCa were included and randomized to receive either OILND or VEILND on one side, with the other technique then used on the contralateral side. The trial was approved by the local ethics committee and was registered on ClinicalTrials.gov (NCT05887921). The primary outcome was the safety of VEILND. Secondary outcomes included intraoperative and postoperative morbidity rates and surgical outcomes for the two procedures, as well as oncological outcomes according to survival estimates. Key findings and limitations: We included 14 patients in the study. Median follow-up was 12 mo (interquartile range [IQR] 12-17). There were no significant differences in operative time and the number of lymph nodes removed between OILND and VEILND. However, the median time to drain removal was significantly shorter in the VEILND group (15 d, IQR 13-17, 95% confidence interval [CI] 12-17) than in the OILND group (27 d, IQR 20-41, 95% CI 24-31; Conclusions and clinical implications: VEILND represents a safe technique to consider for either staging or curative intent in PeCa and seems to have an advantage over OILND in terms of morbidity. Further high-powered studies are warranted to confirm these preliminary results. Patient summary: We compared the outcomes of two different surgical techniques to remove lymph nodes in patients with penile cancer. We found that a video-assisted keyhole surgery approach seems to result in a lower rate of complications than after open surgery.
Language	English
Publishing date	2024-03-21
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	3040546-4
ISSN	2666-1683 ; 2058-4881
ISSN (online)	2666-1683
ISSN	2058-4881
DOI	10.1016/j.euros.2024.02.007
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Article ; Online: Comment on: "Masculinizing genital gender-affirming surgery: metoidioplasty and urethral lengthening".

Falcone, Marco / Oderda, Marco / Gontero, Paolo

International journal of impotence research

2020 Volume 34, Issue 2, Page(s) 229–230

MeSH term(s)	Genitalia ; Humans ; Male ; Sex Reassignment Surgery ; Urethra/surgery
Language	English
Publishing date	2020-04-14
Publishing country	England
Document type	Journal Article ; Comment
ZDB-ID	1034295-3
ISSN	1476-5489 ; 0955-9930
ISSN (online)	1476-5489
ISSN	0955-9930
DOI	10.1038/s41443-020-0272-2
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Article ; Online: Reply to Comment on "Suprapubic Pedicled Phalloplasty in Transgender Men: a Multicentric Retrospective Cohort Analysis".

Falcone, Marco / Oderda, Marco / Gontero, Paolo

International journal of impotence research

2020 Volume 33, Issue 8, Page(s) 862–863

MeSH term(s)	Cohort Studies ; Humans ; Male ; Retrospective Studies ; Sex Reassignment Surgery ; Transgender Persons ; Transsexualism/surgery
Language	English
Publishing date	2020-05-06
Publishing country	England
Document type	Journal Article ; Comment
ZDB-ID	1034295-3
ISSN	1476-5489 ; 0955-9930
ISSN (online)	1476-5489
ISSN	0955-9930
DOI	10.1038/s41443-020-0274-0
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Article: Awake Da Vinci robotic partial nephrectomy: First case report ever in a situation of need.

Gontero, Paolo / Oderda, Marco / Calleris, Giorgio / Allasia, Marco / Balagna, Roberto / Gobbi, Fabio

Urology case reports

2022 Volume 42, Page(s) 102008

Abstract: We report a unique case of a robotic partial nephrectomy performed under continuous spinal anesthesia (CSA). A 63-year-old woman, active smoker with mild obesity and previous right pneumonectomy, was diagnosed with a growing 5.5-cm renal right cystic ... ...

Abstract	We report a unique case of a robotic partial nephrectomy performed under continuous spinal anesthesia (CSA). A 63-year-old woman, active smoker with mild obesity and previous right pneumonectomy, was diagnosed with a growing 5.5-cm renal right cystic tumor. Being at high risk for general anesthesia, a loco-regional approach was indicated. Therefore, after multidisciplinary discussion, a robotic-assisted partial nephrectomy under CSA was considered mandatory. After T4-T5 sensory and motor block, retroperitoneoscopic robot-assisted surgery was successfully performed. Postoperative period was uneventful, with optimal pain control. This unique case demonstrates the feasibility of robotic surgery under CSA, for imperative indications.
Language	English
Publishing date	2022-01-22
Publishing country	United States
Document type	Case Reports
ZDB-ID	2745459-9
ISSN	2214-4420
ISSN	2214-4420
DOI	10.1016/j.eucr.2022.102008
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Article ; Online: Surgical and Functional Outcomes of Penile Amputation and Perineal Urethrostomy Configuration in Invasive Penile Cancer.

Falcone, Marco / Preto, Mirko / Ferro, Ilaria / Cirigliano, Lorenzo / Peretti, Federica / Plamadeala, Natalia / Scavone, Martina / Lavagno, Federico / Oderda, Marco / Gontero, Paolo

Urology

2023 Volume 177, Page(s) 227

Abstract: Objective: The treatment of invasive penile cancer is based on partial or total penectomy and perineal urethrostomy configuration.: Materials and methods: A single-center retrospective analysis was conducted from January 2018 to December 2022. Data ... ...

Abstract	Objective: The treatment of invasive penile cancer is based on partial or total penectomy and perineal urethrostomy configuration. Materials and methods: A single-center retrospective analysis was conducted from January 2018 to December 2022. Data were extracted from clinical records and operative notes. As primary outcomes, surgical complications were described. Oncological outcomes through cancer-specific survival and overall survival were analyzed. Patient survival was estimated by a Kaplan-Meier analysis. Functional outcomes were assessed through the administration of the International Prostatic Symptoms Score (IPSS) questionnaire at 3 months follow-up. Results: Overall 10 patients were enrolled. The median follow-up was 16 months (Interquartile range (IQR 12-18)). The median age was 71 years (IQR 63-79). Operative time was set at 195 minutes (IQR 155-275). The median hospital stay was 8 days (IQR: 6-10). Postoperative complications occurred in 20% of patients, in 1 case surgical revision was necessary. Positive surgical margins were detected only in 1 patient. The median catheterization time was 15 days (IQR: 15-32). One patient developed local recurrence. At 1 year, the cancer-specific survival was 80% and overall survival was 60%. The median preoperative IPSS was 15 (IQR 12-19). The median postoperative IPSS was 6 (IQR 5-7). Conclusion: Penile amputation and perineal urethrostomy configuration was demonstrated to be a safe and effective procedure to address invasive penile cancer.
MeSH term(s)	Male ; Humans ; Aged ; Penile Neoplasms/surgery ; Retrospective Studies ; Penis/surgery ; Urethra/surgery ; Amputation, Surgical ; Treatment Outcome
Language	English
Publishing date	2023-04-19
Publishing country	United States
Document type	Video-Audio Media
ZDB-ID	192062-5
ISSN	1527-9995 ; 0090-4295
ISSN (online)	1527-9995
ISSN	0090-4295
DOI	10.1016/j.urology.2023.04.005
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Zs.A 1142: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Surgical Outcomes of Glansectomy and Split Thickness Skin Graft Reconstruction for Localized Penile Cancer.

Falcone, Marco / Oderda, Marco / Calleris, Giorgio / Peretti, Federica / Gontero, Paolo

Urology

2021 Volume 152, Page(s) 195

Abstract: Introduction: The management of localized penile cancer is based on organ-sparing approaches. Our aim is to report surgical outcomes of glansectomy (GS) and split thickness skin graft (STSG) reconstruction in a consecutive series of penile cancers.: ... ...

Abstract	Introduction: The management of localized penile cancer is based on organ-sparing approaches. Our aim is to report surgical outcomes of glansectomy (GS) and split thickness skin graft (STSG) reconstruction in a consecutive series of penile cancers. Patients and methods: Patients with a localized penile cancer underwent GS and STSG reconstruction in tertiary referral center. Data were extrapolated from a single center prospective database starting from May 2013 to August 2019. Two different techniques are presented in the video abstract: - a standard GS with dissection over the Bucks' fascia. - a salvage GS with dissection under Bucks' fascia. Results: A total of 34 patients were enrolled. 30 patients underwent a standard GS, whether a salvage GS was performed in the remainders. The apex of corpora cavernosa was transected in 5 cases due to suspicious of local invasion. Median follow-up was 12 (12-41) months. Operative time was 150 (105-180) minutes. Hospital stay was 2 (1-3) days. A modified TODGA compressive dressing and a catheter were applied and left in place for 5 days. After that a saline washing was used for 2 weeks. The incidence of intraoperative complications was minimal (2.9%). Positive surgical margins were detected in 2.9% of cases, requiring a salvage surgery. The incidence of postoperative complications was 29.4%: 11.7% were classified as Grade 1, 8.8% as Grade 2 and 8.8% as Grade 3a according to Clavien-Dindo classification. 1-year recurrence free-survival (RFS) was 88.2%. 1-y cancer-specific (CSS) and overall survival (OS) resulted 91.2% in both cases. Limitations of the study were the retrospective and single centre nature of the study, the lack of comparative group, the limited number of cases and of follow-up. Conclusions: GS and STSG reconstruction represents a safe procedure burden by a low incidence of postoperative complications providing a satisfactory cancer control, with a minimal risk of local recurrence.
MeSH term(s)	Disease-Free Survival ; Follow-Up Studies ; Humans ; Incidence ; Male ; Margins of Excision ; Neoplasm Recurrence, Local/epidemiology ; Neoplasm Recurrence, Local/prevention & control ; Organ Sparing Treatments/adverse effects ; Organ Sparing Treatments/methods ; Penile Neoplasms/mortality ; Penile Neoplasms/pathology ; Penile Neoplasms/surgery ; Penis/pathology ; Penis/surgery ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Prospective Studies ; Retrospective Studies ; Skin Transplantation/adverse effects ; Skin Transplantation/methods ; Urologic Surgical Procedures, Male/adverse effects ; Urologic Surgical Procedures, Male/methods
Language	English
Publishing date	2021-04-01
Publishing country	United States
Document type	Journal Article ; Video-Audio Media
ZDB-ID	192062-5
ISSN	1527-9995 ; 0090-4295
ISSN (online)	1527-9995
ISSN	0090-4295
DOI	10.1016/j.urology.2021.03.022
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Zs.A 1142: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Correction to: The outcomes of surgical management options for adult acquired buried penis.

Falcone, Marco / Preto, Mirko / Timpano, Massimiliano / Oderda, Marco / Plamadeala, Natalia / Cirigliano, Lorenzo / Blecher, Gideon / Peretti, Federica / Ferro, Ilaria / Gontero, Paolo

International journal of impotence research

2022 Volume 35, Issue 8, Page(s) 767

Language	English
Publishing date	2022-12-28
Publishing country	England
Document type	Published Erratum
ZDB-ID	1034295-3
ISSN	1476-5489 ; 0955-9930
ISSN (online)	1476-5489
ISSN	0955-9930
DOI	10.1038/s41443-022-00657-2
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Article ; Online: AUTHOR REPLY.

Marra, Giancarlo / Marquis, Alessandro / Calleris, Giorgio / Oderda, Marco / Gontero, Paolo

Urology

2020 Volume 140, Page(s) 131

Language	English
Publishing date	2020-05-27
Publishing country	United States
Document type	Journal Article ; Comment
ZDB-ID	192062-5
ISSN	1527-9995 ; 0090-4295
ISSN (online)	1527-9995
ISSN	0090-4295
DOI	10.1016/j.urology.2019.11.081
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Article ; Online: How uro-oncology has been affected by COVID-19 emergency? Data from Piedmont/Valle d'Aosta Oncological Network, Italy.

Oderda, Marco / Calleris, Giorgio / Falcone, Marco / Fasolis, Giuseppe / Muto, Giovanni / Oderda, Gianluca / Porpiglia, Francesco / Volpe, Alessandro / Bertetto, Oscar / Gontero, Paolo

Urologia

2021 Volume 88, Issue 1, Page(s) 3–8

Abstract: Introduction: Coronavirus disease 2019 (COVID-19) pandemic has dramatically hit all Europe and Northern Italy in particular. The reallocation of medical resources has caused a sharp reduction in the activity of many medical disciplines, including ... ...

Abstract	Introduction: Coronavirus disease 2019 (COVID-19) pandemic has dramatically hit all Europe and Northern Italy in particular. The reallocation of medical resources has caused a sharp reduction in the activity of many medical disciplines, including urology. The restricted availability of resources is expected to cause a delay in the treatment of urological cancers and to negatively influence the clinical history of many cancer patients. In this study, we describe COVID-19 impact on uro-oncological management in Piedmont/Valle d'Aosta, estimating its future impact. Methods: We performed an online survey in 12 urological centers, belonging to the Oncological Network of Piedmont/Valle d'Aosta, to estimate the impact of COVID-19 emergency on their practice. On this basis, we then estimated the medical working capacity needed to absorb all postponed uro-oncological procedures. Results: Most centers (77%) declared to be "much"/"very much" affected by COVID-19 emergency. If uro-oncological consultations for newly diagnosed cancers were often maintained, follow-up consultations were more than halved or even suspended in around two out of three centers. In-office and day-hospital procedures were generally only mildly reduced, whereas major uro-oncological procedures were more than halved or even suspended in 60% of centers. To clear waiting list backlog, the urological working capacity should dramatically increase in the next months; delays greater than 1 month are expected for more than 50% of uro-oncological procedures. Conclusions: COVID-19 emergency has dramatically slowed down uro-oncological activity in Piedmont and Valle d'Aosta. Ideally, uro-oncological patients should be referred to COVID-19-free tertiary urological centers to ensure a timely management.
MeSH term(s)	Appointments and Schedules ; COVID-19/epidemiology ; Continuity of Patient Care ; Female ; Health Care Surveys ; Health Services Accessibility ; Humans ; Italy/epidemiology ; Kidney Neoplasms/epidemiology ; Kidney Neoplasms/surgery ; Male ; Medical Oncology/organization & administration ; Medical Oncology/statistics & numerical data ; Pandemics ; Procedures and Techniques Utilization ; Prostatic Neoplasms/epidemiology ; Prostatic Neoplasms/surgery ; SARS-CoV-2 ; Urinary Bladder Neoplasms/epidemiology ; Urinary Bladder Neoplasms/surgery ; Urologic Neoplasms/epidemiology ; Urologic Neoplasms/surgery ; Urologic Surgical Procedures/statistics & numerical data ; Urology/organization & administration ; Urology/statistics & numerical data
Language	English
Publishing date	2021-02-25
Publishing country	United States
Document type	Journal Article
ZDB-ID	204043-8
ISSN	1724-6075 ; 0376-0057 ; 0391-5603
ISSN (online)	1724-6075
ISSN	0376-0057 ; 0391-5603
DOI	10.1177/0391560320946186
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