LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 285

Search options

  1. Article ; Online: The Impact of COVID-19 on Diabetes Research in Canada.

    Dyck, Jason R B

    Canadian journal of diabetes

    2020  Volume 44, Issue 5, Page(s) 369

    MeSH term(s) Betacoronavirus ; Biomedical Research/economics ; Biomedical Research/trends ; COVID-19 ; Canada/epidemiology ; Coronavirus Infections/epidemiology ; Coronavirus Infections/therapy ; Diabetes Mellitus/epidemiology ; Diabetes Mellitus/therapy ; Humans ; Pandemics ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/therapy ; Resource Allocation/economics ; Resource Allocation/trends ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-05-13
    Publishing country Canada
    Document type Editorial
    ISSN 2352-3840
    ISSN (online) 2352-3840
    DOI 10.1016/j.jcjd.2020.05.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  2. Article ; Online: The therapeutic potential of ketones in cardiometabolic disease: impact on heart and skeletal muscle.

    Soni, Shubham / Tabatabaei Dakhili, Seyed Amirhossein / Ussher, John R / Dyck, Jason R B

    American journal of physiology. Cell physiology

    2024  Volume 326, Issue 2, Page(s) C551–C566

    Abstract: β-Hydroxybutyrate (βOHB) is the major ketone in the body, and it is recognized as a metabolic energy source and an important signaling molecule. While ketone oxidation is essential in the brain during prolonged fasting/starvation, other organs such as ... ...

    Abstract β-Hydroxybutyrate (βOHB) is the major ketone in the body, and it is recognized as a metabolic energy source and an important signaling molecule. While ketone oxidation is essential in the brain during prolonged fasting/starvation, other organs such as skeletal muscle and the heart also use ketones as metabolic substrates. Additionally, βOHB-mediated molecular signaling events occur in heart and skeletal muscle cells, and via metabolism and/or signaling, ketones may contribute to optimal skeletal muscle health and cardiac function. Of importance, when the use of ketones for ATP production and/or as signaling molecules becomes disturbed in the presence of underlying obesity, type 2 diabetes, and/or cardiovascular diseases, these changes may contribute to cardiometabolic disease. As a result of these disturbances in cardiometabolic disease, multiple approaches have been used to elevate circulating ketones with the goal of optimizing either ketone metabolism or ketone-mediated signaling. These approaches have produced significant improvements in heart and skeletal muscle during cardiometabolic disease with a wide range of benefits that include improved metabolism, weight loss, better glycemic control, improved cardiac and vascular function, as well as reduced inflammation and oxidative stress. Herein, we present the evidence that indicates that ketone therapy could be used as an approach to help treat cardiometabolic diseases by targeting cardiac and skeletal muscles.
    MeSH term(s) Humans ; Ketones/therapeutic use ; Ketones/metabolism ; Diabetes Mellitus, Type 2/drug therapy ; Diabetes Mellitus, Type 2/metabolism ; Muscle, Skeletal/metabolism ; Myocardium/metabolism ; 3-Hydroxybutyric Acid/metabolism ; Heart Failure/metabolism
    Chemical Substances Ketones ; 3-Hydroxybutyric Acid (TZP1275679)
    Language English
    Publishing date 2024-01-09
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 392098-7
    ISSN 1522-1563 ; 0363-6143
    ISSN (online) 1522-1563
    ISSN 0363-6143
    DOI 10.1152/ajpcell.00501.2023
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Uc I Zs.89: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: The Multiple Effects of SGLT2 Inhibitors Suggest Potential Benefit in COVID-19 Patients.

    Soni, Shubham / Dyck, Jason R B

    The Canadian journal of cardiology

    2020  Volume 36, Issue 10, Page(s) 1691.e3

    MeSH term(s) Anti-Inflammatory Agents/therapeutic use ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/drug therapy ; Coronavirus Infections/immunology ; Humans ; Inflammation/drug therapy ; Inflammation/immunology ; Pandemics ; Pneumonia, Viral/drug therapy ; Pneumonia, Viral/immunology ; SARS-CoV-2 ; Sodium-Glucose Transporter 2 Inhibitors/therapeutic use
    Chemical Substances Anti-Inflammatory Agents ; Sodium-Glucose Transporter 2 Inhibitors
    Keywords covid19
    Language English
    Publishing date 2020-07-24
    Publishing country England
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 632813-1
    ISSN 1916-7075 ; 0828-282X
    ISSN (online) 1916-7075
    ISSN 0828-282X
    DOI 10.1016/j.cjca.2020.07.230
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2150: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: The Impact of COVID-19 on Diabetes Research in Canada

    Dyck, Jason R.B.

    Canadian Journal of Diabetes

    2020  Volume 44, Issue 5, Page(s) 369

    Keywords Internal Medicine ; Endocrinology, Diabetes and Metabolism ; Endocrinology ; General Medicine ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 2205004-8
    ISSN 1499-2671
    ISSN 1499-2671
    DOI 10.1016/j.jcjd.2020.05.002
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 6154: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: Medical cannabis authorization and risk of emergency department visits and hospitalization due to psychotic disorders: A propensity score-matched cohort study.

    Dubois, Cerina / Lunghi, Carlotta / Eurich, Dean T / Dyck, Jason R B / Hyshka, Elaine / Hanlon, John G / Zongo, Arsene

    Schizophrenia research

    2024  Volume 264, Page(s) 534–542

    Abstract: Despite evidence showing that recreational cannabis use is associated with a higher risk of psychotic disorders, this risk has not been well characterized for patients using medical cannabis. Therefore, this study assessed the risk of emergency ... ...

    Abstract Despite evidence showing that recreational cannabis use is associated with a higher risk of psychotic disorders, this risk has not been well characterized for patients using medical cannabis. Therefore, this study assessed the risk of emergency department (ED) visits and hospitalization for psychotic disorders (the study outcome) among adult patients authorized to use medical cannabis. We performed a retrospective cohort study on patients authorized to use medical cannabis in a group of Ontario cannabis clinics between 2014 and 2019. Using clinical and health administrative data, each patient was matched by propensity scores to up to 3 population-based controls. Conditional Cox proportional hazards regressions were used to assess the risk. Among 54,006 cannabis patients matched to 161,265 controls, 39 % were aged ≤50 years, and 54 % were female. Incidence rates for psychotic disorders were 3.00/1000 person-years (95%CI: 2.72-3.32) in the cannabis group and 1.88/1000 person-years (1.75-2.03) in the control group. A significant association was observed, with an adjusted hazard ratio of 1.38 (95%CI: 1.19-1.60) in the total sample and 1.63 (1.40-1.91) in patients without previous psychotic disorders. The results suggest that cannabis authorization should include a benefit-risk assessment of psychotic disorders to minimize the risk of events requiring emergency attention.
    MeSH term(s) Adult ; Humans ; Female ; Male ; Cohort Studies ; Medical Marijuana ; Retrospective Studies ; Propensity Score ; Emergency Room Visits ; Psychotic Disorders/epidemiology ; Psychotic Disorders/etiology ; Hospitalization ; Cannabis ; Emergency Service, Hospital
    Chemical Substances Medical Marijuana
    Language English
    Publishing date 2024-02-07
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 639422-x
    ISSN 1573-2509 ; 0920-9964
    ISSN (online) 1573-2509
    ISSN 0920-9964
    DOI 10.1016/j.schres.2024.01.029
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2351: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 543: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article ; Online: The Multiple Effects of SGLT2 Inhibitors Suggest Potential Benefit in COVID-19 Patients

    Soni, Shubham / Dyck, Jason R.B.

    Canadian Journal of Cardiology

    2020  Volume 36, Issue 10, Page(s) 1691.e3

    Keywords Cardiology and Cardiovascular Medicine ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 632813-1
    ISSN 1916-7075 ; 0828-282X
    ISSN (online) 1916-7075
    ISSN 0828-282X
    DOI 10.1016/j.cjca.2020.07.230
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2150: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: Correction to "Chemical Composition of Commercial Cannabis".

    Wishart, David S / Hiebert-Giesbrecht, Mickel / Inchehborouni, Gozal / Cao, Xuan / Guo, An Chi / LeVatte, Marcia A / Torres-Calzada, Claudia / Gautam, Vasuk / Johnson, Mathew / Liigand, Jaanus / Wang, Fei / Zahraei, Shirin / Bhumireddy, Sudarshana / Wang, Yilin / Zheng, Jiamin / Mandal, Rupasri / Dyck, Jason R B

    Journal of agricultural and food chemistry

    2024  

    Language English
    Publishing date 2024-02-27
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 241619-0
    ISSN 1520-5118 ; 0021-8561
    ISSN (online) 1520-5118
    ISSN 0021-8561
    DOI 10.1021/acs.jafc.4c01418
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1172: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article ; Online: Pharmacological Inhibition of Succinyl Coenzyme A:3-Ketoacid Coenzyme A Transferase Alleviates the Progression of Diabetic Cardiomyopathy.

    Greenwell, Amanda A / Tabatabaei Dakhili, Seyed Amirhossein / Wagg, Cory S / Saed, Christina T / Chan, Jordan S F / Yang, Kunyan / Mangra-Bala, Indiresh A / Stenlund, Magnus J / Eaton, Farah / Gopal, Keshav / Dyck, Jason R B / Lopaschuk, Gary D / Ussher, John R

    Journal of the American Heart Association

    2024  Volume 13, Issue 7, Page(s) e032697

    MeSH term(s) Humans ; Coenzyme A-Transferases ; Diabetic Cardiomyopathies/drug therapy ; Ketone Bodies ; Diabetes Mellitus
    Chemical Substances Coenzyme A-Transferases (EC 2.8.3.-) ; Ketone Bodies
    Language English
    Publishing date 2024-03-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 2653953-6
    ISSN 2047-9980 ; 2047-9980
    ISSN (online) 2047-9980
    ISSN 2047-9980
    DOI 10.1161/JAHA.123.032697
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top