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  1. Article ; Online: Dealing with confounding in observational studies.

    Fumo-Dos-Santos, Cristiane / Ferreira, Juliana Carvalho

    Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia

    2023  Volume 49, Issue 4, Page(s) e20230281

    Language Portuguese
    Publishing date 2023-09-18
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 2223157-2
    ISSN 1806-3756 ; 1806-3713
    ISSN (online) 1806-3756
    ISSN 1806-3713
    DOI 10.36416/1806-3756/e20230281
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Could Teledentistry Be a Solution in the Diagnosis of Oral Lesions?

    Carrard, Vinicius Coelho / Roxo-Gonçalves, Michelle / Santos, Ingrid da Silva / Romanini, Juliana / Carvalho, Fabiana / Umpierre, Roberto Nunes

    Telemedicine journal and e-health : the official journal of the American Telemedicine Association

    2024  

    Abstract: In recent years, teledentistry has gained visibility, especially because of the COVID-19 pandemic. Concerning oral medicine, there is great expectation, particularly about its potential to promote early diagnosis of oral lesions. In southern Brazil, two ... ...

    Abstract In recent years, teledentistry has gained visibility, especially because of the COVID-19 pandemic. Concerning oral medicine, there is great expectation, particularly about its potential to promote early diagnosis of oral lesions. In southern Brazil, two initiatives have shown a positive influence on each other and have led to greater awareness of oral cancer and more access to qualified advice on diagnosing and managing oral lesions. Although the contributions of this approach are promising, there are barriers to be overcome.
    Language English
    Publishing date 2024-03-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2035659-6
    ISSN 1556-3669 ; 1530-5627
    ISSN (online) 1556-3669
    ISSN 1530-5627
    DOI 10.1089/tmj.2023.0404
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4576: Show issues Location:
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  3. Article ; Online: Correction: Hotspots and Trends of Layered Double Hydroxide-based Adsorbents for Polluted Water Treatment: Insights from Bibliometric Analysis.

    Paulino, Juliana Cristina Pereira Lima / da Silva, Anamália Ferreira / da Silva Santos, Danilo Henrique / de Carvalho Nagliate, Patrícia / Meili, Lucas

    Environmental management

    2023  Volume 71, Issue 5, Page(s) 1110

    Language English
    Publishing date 2023-01-13
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 1478932-2
    ISSN 1432-1009 ; 0364-152X
    ISSN (online) 1432-1009
    ISSN 0364-152X
    DOI 10.1007/s00267-023-01786-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Thermo-rheological properties of chitosan hydrogels with hydroxypropyl methylcellulose and methylcellulose.

    Dos Santos Carvalho, Juliana Domingues / Rabelo, Renata Santos / Hubinger, Miriam Dupas

    International journal of biological macromolecules

    2022  Volume 209, Issue Pt A, Page(s) 367–375

    Abstract: Thermal and rheological properties of methylcellulose (MC) and hydroxypropyl methylcellulose (HPMC) hydrogels with chitosan (CHI) were investigated to verify the potential application of these blends as structured systems for oil transport (emulgel, ... ...

    Abstract Thermal and rheological properties of methylcellulose (MC) and hydroxypropyl methylcellulose (HPMC) hydrogels with chitosan (CHI) were investigated to verify the potential application of these blends as structured systems for oil transport (emulgel, oleogels, and bigels). FTIR confirmed hydrophobic interactions of cellulosic polymers with chitosan. In the temperature sweep, the thermosensitive hydrogels showed their reduced gel point compared to the original polymers. The gelation temperature was reduced from 66.9 °C for pure HPMC to 43.6 °C and 43.6 °C (MC pure polymer) to 39.3 °C when 30% CHI was added for both cases. The addition of 20 and 30% chitosan is enough to modify the extension of the gelation temperature of these polymers. These results indicate that the addition of chitosan enables MC and HPMC to form gels at lower temperatures, which could allow milder thermal conditions to be applied in processing oil carrier systems.
    MeSH term(s) Chitosan/chemistry ; Hydrogels/chemistry ; Hypromellose Derivatives ; Methylcellulose/chemistry ; Polymers ; Rheology ; Temperature
    Chemical Substances Hydrogels ; Polymers ; Hypromellose Derivatives (3NXW29V3WO) ; Methylcellulose (9004-67-5) ; Chitosan (9012-76-4)
    Language English
    Publishing date 2022-04-10
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 282732-3
    ISSN 1879-0003 ; 0141-8130
    ISSN (online) 1879-0003
    ISSN 0141-8130
    DOI 10.1016/j.ijbiomac.2022.04.035
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Oil-in-water emulsion gels stabilized with cellulosic polymers and chitosan: Themorheological and physical-chemical evaluation.

    Dos Santos Carvalho, Juliana Domingues / Rabelo, Renata Santos / Cerqueira E Silva, Klycia Fidelis / Hubinger, Miriam Dupas

    International journal of biological macromolecules

    2023  Volume 236, Page(s) 123828

    Abstract: This research evaluated the use of different polymer ratios, hydroxypropyl methylcellulose (HPMC) and methylcellulose (MC) with chitosan (CHI), in the production of emulgel by emulsification. The concentration was fixed at 2 % (w/v) for all polymers. 60/ ... ...

    Abstract This research evaluated the use of different polymer ratios, hydroxypropyl methylcellulose (HPMC) and methylcellulose (MC) with chitosan (CHI), in the production of emulgel by emulsification. The concentration was fixed at 2 % (w/v) for all polymers. 60/40 sunflower oil-in-water emulgels were made with a cellulosic polymer:chitosan ratio of (80:20), (70:30), and (60:40), respectively. The objective was to study how different proportions of a cellulosic polymer combined with chitosan can affect the stability, microstructure, and rheology of the emulgels to be used as potential oil carrier systems. Droplet size and microscopy results show oil-in-water (O/W) emulgels, and their interface was stabilized by mixing polymeric pairs, HPMC:CHI or MC:CHI. In the thermal analysis, it was identified in the entire temperature range studied (5 to 85 °C) that both emulgels, HPMC:CHI and MC:CHI, were presented as gels (G' > G″). Thus, the addition of CHI to the systems modified their gelling behavior. Microscopy revealed that the emulsions at the 7th and 10th week of storage showed similar characteristics to the fresh emulsion. Therefore, these results indicate that the emulgels present good thermal resistance, the predominance of elastic behavior, and can retain high concentrations of oil in their structure (96 to 99 %).
    MeSH term(s) Polymers/chemistry ; Chitosan/chemistry ; Emulsions/chemistry ; Gels/chemistry ; Rheology ; Hypromellose Derivatives ; Water/chemistry
    Chemical Substances Polymers ; Chitosan (9012-76-4) ; Emulsions ; Gels ; Hypromellose Derivatives (3NXW29V3WO) ; Water (059QF0KO0R)
    Language English
    Publishing date 2023-02-27
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 282732-3
    ISSN 1879-0003 ; 0141-8130
    ISSN (online) 1879-0003
    ISSN 0141-8130
    DOI 10.1016/j.ijbiomac.2023.123828
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Physical Activity and Sedentary Behavior as Treatable Traits for Clinical Control in Moderate-to-Severe Asthma.

    de Lima, Fabiano F / Dos Santos, Juliana M B / Lunardi, Adriana C / de Oliveira, Joice M / Freitas, Patrícia D / Kim, Fabiana S / Agondi, Rosana Câmara / Carvalho-Pinto, Regina M / Furlanetto, Karina C / Carvalho, Celso R F

    The journal of allergy and clinical immunology. In practice

    2024  

    Abstract: Background: Physical activity and sedentary behavior are treatable traits that may impact asthma control in distinct manners, but this impact remains poorly understood.: Objective: To evaluate the influence of physical activity and sedentary behavior ...

    Abstract Background: Physical activity and sedentary behavior are treatable traits that may impact asthma control in distinct manners, but this impact remains poorly understood.
    Objective: To evaluate the influence of physical activity and sedentary behavior on clinical control in adults with moderate-to-severe asthma.
    Methods: This cross-sectional, multicentric study included 426 individuals with moderate-to-severe asthma. Assessments included physical activity and sedentary time (actigraphy), clinical asthma control (Asthma Control Questionnaire [ACQ]), quality of life (Asthma Quality of Life Questionnaire), anxiety and depression symptoms (Hospital Anxiety and Depression Scale), anthropometric data, and lung function. Participants were grouped according to physical activity levels and sedentary behavior.
    Results: Participants who walked ≥7500 steps/day presented better ACQ scores than those who walked <7500 steps/day (P < .05), independent of sedentary status. The percentage of patients with controlled asthma was higher in the active/sedentary (43.9%) and active/nonsedentary (43.8%) groups than in the inactive/sedentary (25.4%) and inactive/nonsedentary (23.9%) groups (P < .02). The likelihood of having uncontrolled asthma according to the treatable traits of physical inactivity (odds ratio [95% confidence interval]: 2.36 [1.55-3.59]), higher anxiety (2.26 [1.49-3.42]), and depression symptoms (1.95 [1.28-2.95]) was significant (P ≤ .002). Obesity and sedentary time were not associated with asthma control.
    Conclusions: Our results show that ≥7500 steps/day is associated with better asthma control independent of sedentary time in adults with moderate-to-severe asthma. Physical inactivity, anxiety, and depression symptoms are associated with higher odds of uncontrolled asthma. These results suggest that interventions should mainly focus on increasing physical activity rather than reducing sedentary time.
    Language English
    Publishing date 2024-03-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2843237-X
    ISSN 2213-2201 ; 2213-2198
    ISSN (online) 2213-2201
    ISSN 2213-2198
    DOI 10.1016/j.jaip.2024.03.012
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    Zs.A 7086: Show issues Location:
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  7. Article: Optimization of Platelet-Rich Plasma Preparation for Regenerative Medicine: Comparison of Different Anticoagulants and Resuspension Media.

    Carvalho, Alexandra / Ferreira, Ana Filipa / Soares, Maria / Santos, Susana / Tomé, Patrícia / Machado-Simões, Juliana / Pais, Ana Sofia / Sousa, Ana Paula / Paiva, Artur / Almeida-Santos, Teresa

    Bioengineering (Basel, Switzerland)

    2024  Volume 11, Issue 3

    Abstract: Platelet-rich plasma (PRP) has emerged as a promising therapy in regenerative medicine. However, the lack of standardization in PRP preparation protocols presents a challenge in achieving reproducible and accurate results. This study aimed to optimize ... ...

    Abstract Platelet-rich plasma (PRP) has emerged as a promising therapy in regenerative medicine. However, the lack of standardization in PRP preparation protocols presents a challenge in achieving reproducible and accurate results. This study aimed to optimize the PRP preparation protocol by investigating the impact of two different anticoagulants, sodium citrate (SC) and ethylenediaminetetraacetic acid (EDTA), and resuspension media, plasma versus sodium chloride (NaCl). Platelet recovery rates were calculated and compared between groups, in addition to platelet activity and vascular endothelial growth factor (VEGF) released into plasma after PRP activation. The platelet recovery rate was higher with EDTA in comparison to SC (51.04% vs. 29.85%,
    Language English
    Publishing date 2024-02-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2746191-9
    ISSN 2306-5354
    ISSN 2306-5354
    DOI 10.3390/bioengineering11030209
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  8. Article: Body Mass Index but not Physical Activity Level Moderates Lowered Cardiac Baroreflex Sensitivity in People Living with HIV.

    Dos Santos Rangel, Marcus Vinicius / Barros, Juliana Pereira / Peres, Deysiane / DE Carvalho Mira, Pedro Augusto / Martinez, Daniel Godoy / Laterza, Mateus Camaroti / Farinatti, Paulo / Borges, Juliana Pereira

    International journal of exercise science

    2023  Volume 16, Issue 2, Page(s) 700–709

    Abstract: Reduced cardiac baroreflex sensitivity (cBRS) is an autonomic marker associated with a worse cardiovascular prognosis. Whether cBRS is lowered in people living with HIV (PLHIV) is yet unclear, as well as potential moderator effects of body mass index ( ... ...

    Abstract Reduced cardiac baroreflex sensitivity (cBRS) is an autonomic marker associated with a worse cardiovascular prognosis. Whether cBRS is lowered in people living with HIV (PLHIV) is yet unclear, as well as potential moderator effects of body mass index (BMI) or physical activity (PA) level. The present study aims to compare the spontaneous cBRS in PLHIV
    Language English
    Publishing date 2023-06-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2411342-6
    ISSN 1939-795X
    ISSN 1939-795X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: RHOA Therapeutic Targeting in Hematological Cancers.

    Santos, Juliana Carvalho / Profitós-Pelejà, Núria / Sánchez-Vinces, Salvador / Roué, Gaël

    Cells

    2023  Volume 12, Issue 3

    Abstract: Primarily identified as an important regulator of cytoskeletal dynamics, the small GTPase Ras homolog gene family member A (RHOA) has been implicated in the transduction of signals regulating a broad range of cellular functions such as cell survival, ... ...

    Abstract Primarily identified as an important regulator of cytoskeletal dynamics, the small GTPase Ras homolog gene family member A (RHOA) has been implicated in the transduction of signals regulating a broad range of cellular functions such as cell survival, migration, adhesion and proliferation. Deregulated activity of RHOA has been linked to the growth, progression and metastasis of various cancer types. Recent cancer genome-wide sequencing studies have unveiled both
    MeSH term(s) Humans ; rhoA GTP-Binding Protein/genetics ; rhoA GTP-Binding Protein/metabolism ; Signal Transduction ; Neoplasms ; Mutation ; Hematologic Neoplasms/drug therapy ; Hematologic Neoplasms/genetics
    Chemical Substances rhoA GTP-Binding Protein (EC 3.6.5.2) ; RHOA protein, human (124671-05-2)
    Language English
    Publishing date 2023-01-28
    Publishing country Switzerland
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2661518-6
    ISSN 2073-4409 ; 2073-4409
    ISSN (online) 2073-4409
    ISSN 2073-4409
    DOI 10.3390/cells12030433
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Oil-in-water emulsion gels stabilized with cellulosic polymers and chitosan: Themorheological and physical-chemical evaluation

    dos Santos Carvalho, Juliana Domingues / Rabelo, Renata Santos / Cerqueira e Silva, Klycia Fidelis / Hubinger, Miriam Dupas

    International Journal of Biological Macromolecules. 2023 May, v. 236 p.123828-

    2023  

    Abstract: This research evaluated the use of different polymer ratios, hydroxypropyl methylcellulose (HPMC) and methylcellulose (MC) with chitosan (CHI), in the production of emulgel by emulsification. The concentration was fixed at 2 % (w/v) for all polymers. 60/ ... ...

    Abstract This research evaluated the use of different polymer ratios, hydroxypropyl methylcellulose (HPMC) and methylcellulose (MC) with chitosan (CHI), in the production of emulgel by emulsification. The concentration was fixed at 2 % (w/v) for all polymers. 60/40 sunflower oil-in-water emulgels were made with a cellulosic polymer:chitosan ratio of (80:20), (70:30), and (60:40), respectively. The objective was to study how different proportions of a cellulosic polymer combined with chitosan can affect the stability, microstructure, and rheology of the emulgels to be used as potential oil carrier systems. Droplet size and microscopy results show oil-in-water (O/W) emulgels, and their interface was stabilized by mixing polymeric pairs, HPMC:CHI or MC:CHI. In the thermal analysis, it was identified in the entire temperature range studied (5 to 85 °C) that both emulgels, HPMC:CHI and MC:CHI, were presented as gels (G′ > G″). Thus, the addition of CHI to the systems modified their gelling behavior. Microscopy revealed that the emulsions at the 7th and 10th week of storage showed similar characteristics to the fresh emulsion. Therefore, these results indicate that the emulgels present good thermal resistance, the predominance of elastic behavior, and can retain high concentrations of oil in their structure (96 to 99 %).
    Keywords Helianthus annuus ; chitosan ; droplet size ; emulsifying ; emulsions ; heat tolerance ; methylcellulose ; microscopy ; microstructure ; oils ; polymers ; rheology ; temperature ; thermal analysis ; Emulgels ; Cellulosic polymers ; Sol-gel transition ; Mechanical properties
    Language English
    Dates of publication 2023-05
    Publishing place Elsevier B.V.
    Document type Article ; Online
    ZDB-ID 282732-3
    ISSN 1879-0003 ; 0141-8130
    ISSN (online) 1879-0003
    ISSN 0141-8130
    DOI 10.1016/j.ijbiomac.2023.123828
    Database NAL-Catalogue (AGRICOLA)

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