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  1. Article: The Impact of the Covid-19 Pandemic on Stroke Volume.

    Pasarikovski, Christopher R / da Costa, Leodante

    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques

    2020  Volume 47, Issue 6, Page(s) 847–848

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/epidemiology ; Emergency Medical Services ; Emergency Service, Hospital ; Fear ; Help-Seeking Behavior ; Hospitalization ; Humans ; Ontario/epidemiology ; Pandemics ; Patient Transfer ; Pneumonia, Viral/epidemiology ; SARS-CoV-2 ; Stroke/epidemiology ; Stroke/therapy ; Thrombectomy
    Keywords covid19
    Language English
    Publishing date 2020-06-04
    Publishing country England
    Document type Letter
    ZDB-ID 197622-9
    ISSN 0317-1671
    ISSN 0317-1671
    DOI 10.1017/cjn.2020.116
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1203: Show issues Location:
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  2. Article: Endovascular treatment for anterior inferior cerebellar artery-posterior inferior cerebellar artery (AICA-PICA) common trunk variant aneurysms: Technical note and literature review.

    Ku, Jerry C / Chavda, Vishal / Palmisciano, Paolo / Pasarikovski, Christopher R / Yang, Victor X D / Kiwan, Ruba / Priola, Stefano M / Chaurasia, Bipin

    Journal of cerebrovascular and endovascular neurosurgery

    2023  Volume 25, Issue 4, Page(s) 452–461

    Abstract: The Anterior Inferior Cerebellar Artery-Posterior Inferior Cerebellar Artery (AICA-PICA) common trunk is a rare variant of cerebral posterior circulation in which a single vessel originating from either the basilar or vertebral arteries supplies both ... ...

    Abstract The Anterior Inferior Cerebellar Artery-Posterior Inferior Cerebellar Artery (AICA-PICA) common trunk is a rare variant of cerebral posterior circulation in which a single vessel originating from either the basilar or vertebral arteries supplies both cerebellum and brainstem territories. We present the first case of an unruptured right AICA-PICA aneurysm treated with flow diversion using a Shield-enhanced pipeline endovascular device (PED, VANTAGE Embolization Device with Shield Technology, Medtronic, Canada). We expand on this anatomic variant and review the relevant literature. A 39-year-old man presented to our treatment center with vertigo and right hypoacusis. The initial head CT/CTA was negative, but a 4-month follow-up MRI revealed a 9 mm fusiform dissecting aneurysm of the right AICA. The patient underwent a repeat head CTA and cerebral angiogram, which demonstrated the presence of an aneurysm on the proximal portion of an AICA-PICA anatomical variant. This was treated with an endovascular approach that included flow diversion via a PED equipped with Shield Technology. The patient's post-procedure period was uneventful, and he was discharged home after two days with an intact neurological status. The patient is still asymptomatic after a 7-month follow-up, with MR angiogram evidence of stable aneurysm obliteration and no ischemic lesions. Aneurysms of the AICA-PICA common trunk variants have a high morbidity risk due to the importance and extent of the territory vascularized by a single vessel. Endovascular treatment with flow diversion proved to be both safe and effective in obliterating unruptured cases.
    Language English
    Publishing date 2023-04-12
    Publishing country Korea (South)
    Document type Journal Article
    ISSN 2234-8565
    ISSN 2234-8565
    DOI 10.7461/jcen.2023.E2022.10.011
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  3. Article ; Online: Carotid stenting for symptomatic carotid artery web: Multicenter experience.

    Pasarikovski, Christopher R / Lynch, Jeremy / Corrin, Michael / Ku, Jerry C / Kumar, Ashish / Pereira, Vitor M / Krings, Timo / da Costa, Leodante / Black, Sandra E / Agid, Ronit / Yang, Victor Xd

    Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences

    2024  , Page(s) 15910199231226293

    Abstract: Objective: Carotid artery webs are an underappreciated cause of recurrent ischemic stroke, and may represent a significant portion of cryptogenic stroke. Evidence-based guidelines for the management of symptomatic carotid webs do not exist. The goal of ... ...

    Abstract Objective: Carotid artery webs are an underappreciated cause of recurrent ischemic stroke, and may represent a significant portion of cryptogenic stroke. Evidence-based guidelines for the management of symptomatic carotid webs do not exist. The goal of this study is to audit our local experience for patients with symptomatic carotid artery webs undergoing carotid stenting as a treatment option, along with describing the hypothesized dynamic physiology of carotid webs.
    Methods: All patients undergoing stenting for symptomatic carotid artery web at two comprehensive regional stroke centers with high endovascular thrombectomy volume from January 1, 2012 to March 1, 2021 were included. The modified Rankin Scale (mRS) score was used to define functional outcome at 3 months after stenting.
    Results: Fourteen consecutive patients with symptomatic carotid artery webs underwent stenting. Twelve patients were female (86%), with a median age of 54 (IQR, 48-64) years across all patients. Stroke was the qualifying event in 12 (86%) patients and TIA in 2. Eleven patients (11/14, 79%) achieved a mRS score of 0-2 at 90 days, 2 (14%) were mRS 3-5, and one patient was lost to follow-up. The median follow-up was 12 months (IQR, 10-12). There was no recurrent stroke or TIA like symptoms in any patients.
    Conclusions: Carotid stenting appears to be safe at preventing recurrent stroke/TIA with a median follow-up of 12 months in this retrospective multicenter observational study.
    Language English
    Publishing date 2024-01-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1354913-3
    ISSN 2385-2011 ; 1591-0199 ; 1123-9344
    ISSN (online) 2385-2011
    ISSN 1591-0199 ; 1123-9344
    DOI 10.1177/15910199231226293
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6325: Show issues Location:
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  4. Article ; Online: Perspective review on applications of optics in cerebral endovascular neurosurgery.

    Pasarikovski, Christopher R / Cardinell, Jillian / Yang, Victor X D

    Journal of biomedical optics

    2019  Volume 24, Issue 3, Page(s) 1–7

    Abstract: Cerebral endovascular neurosurgery has transformed the way we manage cerebrovascular disease. Several landmark trials have demonstrated the effectiveness of endovascular techniques leading to continued technological development and applications for ... ...

    Abstract Cerebral endovascular neurosurgery has transformed the way we manage cerebrovascular disease. Several landmark trials have demonstrated the effectiveness of endovascular techniques leading to continued technological development and applications for various diseases. The utilization of optical technologies and devices is already underway in the field of endovascular neurosurgery. We discuss the contemporary paradigms, challenges, and current optical applications for the most common cerebrovascular diseases: carotid atherosclerotic disease, cerebral aneurysms, intracranial atherosclerosis, and dural arteriovenous fistulas. We also describe needs-based opportunities for future optical applications, with the goal of providing researchers a sense of where we feel optical technologies could impact the way we manage cerebral disease.
    MeSH term(s) Carotid Artery Diseases/diagnostic imaging ; Carotid Artery Diseases/surgery ; Cerebrovascular Disorders/diagnostic imaging ; Cerebrovascular Disorders/surgery ; Endovascular Procedures ; Humans ; Neurosurgical Procedures ; Optical Imaging ; Surgery, Computer-Assisted
    Language English
    Publishing date 2019-03-23
    Publishing country United States
    Document type Journal Article ; Systematic Review
    ZDB-ID 1309154-2
    ISSN 1560-2281 ; 1083-3668
    ISSN (online) 1560-2281
    ISSN 1083-3668
    DOI 10.1117/1.JBO.24.3.030601
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    Zs.A 4699: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: The Impact of the Covid-19 Pandemic on Stroke Volume

    Pasarikovski, Christopher R. / da Costa, Leodante

    Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques

    2020  , Page(s) 1–2

    Keywords Neurology ; Clinical Neurology ; General Medicine ; covid19
    Language English
    Publisher Cambridge University Press (CUP)
    Publishing country uk
    Document type Article ; Online
    ZDB-ID 197622-9
    ISSN 0317-1671
    ISSN 0317-1671
    DOI 10.1017/cjn.2020.116
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    Zs.A 1203: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  7. Article: Optical coherence tomography as an adjunct during carotid artery stenting for carotid web.

    Pasarikovski, Christopher R / Ramjist, Joel / da Costa, Leodante / Yang, Victor X D

    Neurology. Clinical practice

    2020  Volume 9, Issue 6, Page(s) 484–486

    Language English
    Publishing date 2020-02-10
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2645818-4
    ISSN 2163-0933 ; 2163-0402
    ISSN (online) 2163-0933
    ISSN 2163-0402
    DOI 10.1212/CPJ.0000000000000618
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Endovascular optical coherence tomography imaging in cerebrovascular disease.

    Pasarikovski, Christopher R / Ku, Jerry C / Priola, Stefano M / da Costa, Leodante / Yang, Victor X D

    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

    2020  Volume 80, Page(s) 30–37

    Abstract: Endovascular optical coherence tomography (OCT) is the highest resolution imaging modality currently available with spatial resolution of 10 µm. Although originally developed for interventional cardiology, the ability to visualize the luminal environment ...

    Abstract Endovascular optical coherence tomography (OCT) is the highest resolution imaging modality currently available with spatial resolution of 10 µm. Although originally developed for interventional cardiology, the ability to visualize the luminal environment and anatomy, along with the stent-vessel interaction could be of great utility for various cerebrovascular diseases, and the adoption of endovascular OCT imaging in the evolving field of interventional neuroradiology seems instinctive. The purpose of this study is to conduct a systematic review of the literature regarding applications of endovascular OCT in the diagnosis and treatment of cerebrovascular diseases. In addition, the authors report their institutional experience with the use of OCT in carotid atherosclerotic disease, cerebral aneurysms, and acute ischemic stroke. A systematic review of the literature was undertaken. Peer-reviewed articles were collected through MEDLINE, Embase, Scopus, and Cochrane Central Register of Controlled Trials (CENTRAL) searches through March 2020. A total of 34 studies with 598 patients were included in the qualitative synthesis. These include 23 studies of carotid atherosclerotic disease, 7 studies of cerebral aneurysms, and 4 studies of non-aneurysmal posterior circulation pathology. OCT imaging was feasible in 94% of patients with 0.6% complication rate. Endovascular OCT appears to be safe and feasible, allowing clinicians to visualize stent-vessel interactions, aneurysmal healing, and vulnerable atherosclerotic plaque features. OCT carries great promise, however additional investigations are needed before any imposing statement can be made about the role of OCT in cerebrovascular imaging.
    MeSH term(s) Cerebrovascular Disorders/diagnostic imaging ; Female ; Humans ; Male ; Neuroimaging/methods ; Tomography, Optical Coherence/methods
    Language English
    Publishing date 2020-08-17
    Publishing country Scotland
    Document type Journal Article ; Review
    ZDB-ID 1193674-5
    ISSN 1532-2653 ; 0967-5868
    ISSN (online) 1532-2653
    ISSN 0967-5868
    DOI 10.1016/j.jocn.2020.07.064
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    Zs.A 3999: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  9. Article ; Online: Angio-architecture of complex cranial dural arteriovenous fistulas: A single centre retrospective review of treatment modalities and outcomes.

    Priola, Stefano M / Ku, Jerry C / Pasarikovski, Christopher R / Yang, Victor X D / da Costa, Leodante

    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

    2020  Volume 76, Page(s) 87–99

    Abstract: Introduction: Cranial dural arteriovenous fistulas (DAVFs) are rare vascular lesions that often harbour complex angio-architectural features. This subtype of DAVF may require multiple, multimodality, or hybrid treatments. In this paper we aim to ... ...

    Abstract Introduction: Cranial dural arteriovenous fistulas (DAVFs) are rare vascular lesions that often harbour complex angio-architectural features. This subtype of DAVF may require multiple, multimodality, or hybrid treatments. In this paper we aim to identify specific angio-architectural features that are present in complex cranial DAVFs and we report our series with respect to treatment modalities and outcomes.
    Methods: Twenty-five cranial Borden type II and III cranial DAVFs were treated at our Institution from 2013 to 2017. We classified nine (36%) as complex based on specific angio-architectural features. Treatment strategies were based on fistula location, angiographic features and patient's presenting condition. Phone interviews were used to confirm outcome at 6 and 12 months.
    Results: Four patients (45%) presented with acute hydrocephalus, and 3 (33%) with intracranial hemorrhage. Multiple and combined treatment sessions were needed for all complex DAVFs. Five patients required 2 endovascular procedures each. One patient had 2 surgeries. The first line of treatment was endovascular in 6 cases (67%) and surgery in 3 (33%). Two treatment-related (22%) complications occurred. Complete disconnection was achieved in 5 out of 9 patients (55%). Two patients with an incomplete disconnection refused further treatment and were well at last follow up, with a partially treated fistula and persistent CVR. The other 3 patients concluded treatment after the end of our data collection period. At 1 year, 7/9 patients had stable or improved clinical symptoms, and 8/9 patients had GOS of 4 or 5.
    Conclusions: Complex cranial DAVF often require a multidisciplinary approach and multiple treatment sessions should be expected. Specific angio-architectural features that increase DAVF complexity include multiple arterial feeders, especially transosseous or pial, reflux into multiple cortical veins, sinus occlusion/entrapment, venous aneurysms, segmental stenosis, medial or deep location, and association with the deep venous system.
    MeSH term(s) Aged ; Central Nervous System Vascular Malformations/diagnostic imaging ; Central Nervous System Vascular Malformations/pathology ; Central Nervous System Vascular Malformations/therapy ; Cerebral Angiography/methods ; Combined Modality Therapy ; Embolization, Therapeutic/methods ; Endovascular Procedures/methods ; Female ; Humans ; Magnetic Resonance Angiography/methods ; Male ; Middle Aged ; Retrospective Studies ; Treatment Outcome
    Language English
    Publishing date 2020-04-10
    Publishing country Scotland
    Document type Case Reports ; Journal Article
    ZDB-ID 1193674-5
    ISSN 1532-2653 ; 0967-5868
    ISSN (online) 1532-2653
    ISSN 0967-5868
    DOI 10.1016/j.jocn.2020.04.037
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    Zs.A 3999: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  10. Article ; Online: Minimally invasive intrathecal spinal cord imaging with optical coherence tomography.

    Pasarikovski, Christopher R / Ku, Jerry C / Ramjist, Joel / Dobashi, Yuta / Priola, Stefano M / da Costa, Leodante / Kumar, Ashish / Yang, Victor X D

    Journal of biomedical optics

    2021  Volume 26, Issue 5

    Abstract: Significance: Imaging of the spinal cord is challenging due to the surrounding bony anatomy, physiologic motion, and the small diameter of the spinal cord. This precludes the use of non-invasive imaging techniques in assessing structural changes related ...

    Abstract Significance: Imaging of the spinal cord is challenging due to the surrounding bony anatomy, physiologic motion, and the small diameter of the spinal cord. This precludes the use of non-invasive imaging techniques in assessing structural changes related to trauma and evaluating residual function.
    Aim: The purpose of our research was to apply endovascular technology and techniques and construct a preclinical animal model of intrathecal spinal cord imaging using optical coherence tomography (OCT).
    Approach: Five animals (2 Yorkshire Swine and 3 New Zealand Rabbits) were utilized. Intrathecal access was gained using a 16-guage Tuohy, and an OCT catheter was advanced under roadmap technique into the cervical canal. The OCT catheter has a motorized pullback, and a total length of 54 mm of the spinal canal is imaged.
    Results: Image acquisition was successful for all animals. There were no instances of difficult catheter navigation, enabling OCT imaging rostrally to C2. The thecal sac provided excellent thoroughfare for the OCT catheter. The clear cerebrospinal fluid also provided an excellent medium for image acquisition, with no detectable artifact from the contents of the cerebrospinal fluid. The anatomical space of the spinal canal could be readily appreciated including: dural lining of the thecal sac, epidural veins, pial lining of the spinal cord, arachnoid bands, dentate ligaments, and nerve rootlets/roots.
    Conclusion: Minimally invasive intrathecal imaging using endovascular OCT was feasible in this preclinical animal study. The repurposing of an endovascular device for spinal imaging comes with limitations, and a spine-specific device is necessary.
    MeSH term(s) Animals ; Movement ; Rabbits ; Spinal Cord/diagnostic imaging ; Swine ; Tomography, Optical Coherence
    Language English
    Publishing date 2021-05-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1309154-2
    ISSN 1560-2281 ; 1083-3668
    ISSN (online) 1560-2281
    ISSN 1083-3668
    DOI 10.1117/1.JBO.26.5.056002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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