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Article: [Prognostic analysis of definitive radiotherapy for early esophageal carcinoma(T1-2N0M0): a multi-center retrospective study of Jing-Jin-ji Esophageal and Esophagogastric Cancer Radiotherapy Oncology Group].

Lu, N / Wang, X / Li, C / Wang, L / Chen, J Q / Zhang, W C / Wang, X M / Ge, X L / Shen, W B / Hu, M M / Yuan, Q Q / Xu, Y G / Hao, C L / Zhou, Z G / Qie, S / Xiao, Z F / Zhu, S C / Han, C / Qiao, X Y /

Pang, Q S / Wang, P / Zhao, Y D / Sun, X C / Zhang, K X / Li, L / Li, G F / Liu, M L / Wang, Y D

Zhonghua zhong liu za zhi [Chinese journal of oncology

2020 Volume 42, Issue 2, Page(s) 139–144

Abstract: Objective: ...

Abstract	Objective:
MeSH term(s)	Antineoplastic Agents/therapeutic use ; Chemoradiotherapy ; Dose-Response Relationship, Radiation ; Esophageal Neoplasms/drug therapy ; Esophageal Neoplasms/mortality ; Esophageal Neoplasms/pathology ; Esophageal Neoplasms/radiotherapy ; Esophageal Squamous Cell Carcinoma/drug therapy ; Esophageal Squamous Cell Carcinoma/mortality ; Esophageal Squamous Cell Carcinoma/pathology ; Esophageal Squamous Cell Carcinoma/radiotherapy ; Humans ; Prognosis ; Radiotherapy Dosage ; Radiotherapy, Conformal ; Radiotherapy, Intensity-Modulated ; Retrospective Studies
Chemical Substances	Antineoplastic Agents
Language	Chinese
Publishing date	2020-03-02
Publishing country	China
Document type	Journal Article ; Multicenter Study
ZDB-ID	603424-x
ISSN	0253-3766
ISSN	0253-3766
DOI	10.3760/cma.j.issn.0253-3766.2020.02.010
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Article: [Efficacy analysis of the radiotherapy and chemotherapy in patients with stage Ⅳ esophageal squamous carcinoma: a multicenter retrospective study of Jing-Jin-Ji Esophageal and Esophagogastric Cancer Radiotherapy Oncology Group (3JECROG R-01F)].

Hu, M M / Yuan, Q Q / Zhang, X S / Yang, S / Wang, X / Wang, L / Chen, J Q / Zhang, W C / Wang, X M / Ge, X L / Shen, W B / Xu, Y G / Hao, C L / Zhou, Z G / Qie, S / Lu, N / Pang, Q S / Zhao, Y D / Sun, X C /

Li, G F / Li, L / Qiao, X Y / Liu, M L / Wang, Y D / Li, C / Zhu, S C / Han, C / Zhang, K X / Xiao, Z F

Zhonghua zhong liu za zhi [Chinese journal of oncology

2020 Volume 42, Issue 8, Page(s) 676–681

Abstract: Objective: ...

Abstract	Objective:
MeSH term(s)	Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Chemoradiotherapy/methods ; China/epidemiology ; Esophageal Neoplasms/drug therapy ; Esophageal Neoplasms/mortality ; Esophageal Neoplasms/pathology ; Esophageal Neoplasms/radiotherapy ; Esophageal Squamous Cell Carcinoma/drug therapy ; Esophageal Squamous Cell Carcinoma/mortality ; Esophageal Squamous Cell Carcinoma/pathology ; Esophageal Squamous Cell Carcinoma/radiotherapy ; Humans ; Neoplasm Staging ; Radiotherapy, Intensity-Modulated/methods ; Retrospective Studies ; Treatment Outcome
Language	Chinese
Publishing date	2020-08-20
Publishing country	China
Document type	Journal Article
ZDB-ID	603424-x
ISSN	0253-3766
ISSN	0253-3766
DOI	10.3760/cma.j.cn112152-20190327-00197
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Article: Prevalence of chronic kidney disease in Jing adults in China: a village-based study.

Xue, Chao / Ye, Xu D / Li, Wei / Peng, Qian / Ding, Heng Y / Zhang, Ying H / He, Di F / Bai, Xu / Huang, You / Song, Ya S / Pang, Ling / Liao, Yun H

Clinical nephrology

2013 Volume 79, Issue 1, Page(s) 50–56

Abstract: ... Jing community. We determined CKD prevalence and related risk factors in Jing adults.: Methods ... A stratified cluster random sampling method was used in this study comprising 757 Jing adults. Questionnaires ... a protective factor.: Conclusion: Jing adults showed a high CKD prevalence of 15.3%, with a low awareness ...

Abstract	Aim: Chronic kidney disease (CKD) is increasingly recognized as a predictor of end-stage renal and cardiovascular disease. There is no data on CKD prevalence in numerous minority communities of China such as the Guangxi Jing community. We determined CKD prevalence and related risk factors in Jing adults. Methods: A stratified cluster random sampling method was used in this study comprising 757 Jing adults. Questionnaires, physical examinations and laboratory tests including measurements of urinary albumin and hematuria, were performed. Estimated glomerular filtration rate (eGFR) was calculated using the improved Chinese population MDRD formula. CKD-related risk factors were also examined. Results: After standardization for age and gender, the prevalence of albuminuria, haematuria and eGFR < 60 ml/min per 1.73 m2 was 12.5%, 3.8% and 0.4%, respectively Overall CKD prevalence was 15.3%, while the awareness rate was only 11.6%. Females had a significantly higher (p < 0.05) prevalence of albuminuria, hematuria and eGFR < 60 ml/min compared to males. CKD prevalence tended to increase significantly (< 0.05) with increase in age. Using the standardized age and gender ratios, the prevalence of hypertension, diabetes, hyperlipidemia and hyperuricemia was 14.8%, 5.2%, 38% and 16.2%, respectively, with awareness of 41.0%, 41.2%, 6.6% and 0.9%. Prevalence of overweight or obesity status and metabolic syndrome was 12.1% and 3.0%. Females showed a significantly higher prevalence of hyperuricemia and obesity or overweight status. CKD prevalence was also significantly higher in people with risk diseases. Regression analysis showed that age, gender, hypertension, high cholesterol and diabetes were CKD-related risk factors, while culture (higher education level) was a protective factor. Conclusion: Jing adults showed a high CKD prevalence of 15.3%, with a low awareness rate of 11.6%. Older subjects and females were more susceptible with a high prevalence of hypertension, diabetes, hyperlipidemia, metabolic syndrome etc. being associated closely with CKD.
MeSH term(s)	Adolescent ; Adult ; Age Distribution ; Aged ; Aged, 80 and over ; China/epidemiology ; Female ; Glomerular Filtration Rate ; Humans ; Hyperuricemia/complications ; Hyperuricemia/epidemiology ; Male ; Metabolic Syndrome/complications ; Metabolic Syndrome/epidemiology ; Middle Aged ; Obesity/complications ; Obesity/epidemiology ; Prevalence ; Prognosis ; Renal Insufficiency, Chronic/epidemiology ; Renal Insufficiency, Chronic/etiology ; Renal Insufficiency, Chronic/physiopathology ; Risk Factors ; Rural Population ; Sex Distribution ; Young Adult
Language	English
Publishing date	2013-01
Publishing country	Germany
Document type	Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	185101-9
ISSN	0301-0430
ISSN	0301-0430
DOI	10.5414/CN107511
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Article: [Contribution of Zhenjiu jiayi jing (A-B classic of acupuncture and moxibustion) to surface anatomy].

Pang, Bing / Wang, Zi-xuan

Zhongguo zhen jiu = Chinese acupuncture & moxibustion

2011 Volume 31, Issue 4, Page(s) 371–374

Abstract: The knowledge of surface anatomy in the ancient classic Zhenjiu Jiayi Jing (A-B Classic ...

Abstract	The knowledge of surface anatomy in the ancient classic Zhenjiu Jiayi Jing (A-B Classic of Acupuncture and Moxibustion) is expounded in this article through comprehensive reading of the book and study of surface anatomy. The description and application of body surface landmarks,recording of the length of skeleton at the surface of the body,location of the viscera,palpation on arteries at the surface of the body and dynamic selection of acupoints are studied as well,which provide basis for locating and selecting of acupoints.
MeSH term(s)	Acupuncture/history ; Acupuncture Points ; Anatomy/history ; China ; History, Ancient ; Humans ; Medicine in Literature
Language	Chinese
Publishing date	2011-04
Publishing country	China
Document type	English Abstract ; Historical Article ; Journal Article ; Research Support, Non-U.S. Gov't
ISSN	0255-2930
ISSN	0255-2930
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Article: The coherence between PSMC6 and α-ring in the 26S proteasome is associated with Alzheimer's disease.

Xiong, Jing / Pang, Xinping / Song, Xianghu / Yang, Lin / Pang, Chaoyang

Frontiers in molecular neuroscience

2024 Volume 16, Page(s) 1330853

Abstract: Alzheimer's disease (AD) is a heterogeneous age-dependent neurodegenerative disorder. Its hallmarks involve abnormal proteostasis, which triggers proteotoxicity and induces neuronal dysfunction. The 26S proteasome is an ATP-dependent proteolytic ... ...

Abstract	Alzheimer's disease (AD) is a heterogeneous age-dependent neurodegenerative disorder. Its hallmarks involve abnormal proteostasis, which triggers proteotoxicity and induces neuronal dysfunction. The 26S proteasome is an ATP-dependent proteolytic nanomachine of the ubiquitin-proteasome system (UPS) and contributes to eliminating these abnormal proteins. This study focused on the relationship between proteasome and AD, the hub genes of proteasome, PSMC6, and 7 genes of α-ring, are selected as targets to study. The following three characteristics were observed: 1. The total number of proteasomes decreased with AD progression because the proteotoxicity damaged the expression of proteasome proteins, as evidenced by the downregulation of hub genes. 2. The existing proteasomes exhibit increased activity and efficiency to counterbalance the decline in total proteasome numbers, as evidenced by enhanced global coordination and reduced systemic disorder of proteasomal subunits as AD advances. 3. The synergy of PSMC6 and α-ring subunits is associated with AD. Synergistic downregulation of PSMC6 and α-ring subunits reflects a high probability of AD risk. Regarding the above discovery, the following hypothesis is proposed: The aggregation of pathogenic proteins intensifies with AD progression, then proteasome becomes more active and facilitates the UPS selectively targets the degradation of abnormal proteins to maintain CNS proteostasis. In this paper, bioinformatics and support vector machine learning methods are applied and combined with multivariate statistical analysis of microarray data. Additionally, the concept of entropy was used to detect the disorder of proteasome system, it was discovered that entropy is down-regulated continually with AD progression against system chaos caused by AD. Another conception of the matrix determinant was used to detect the global coordination of proteasome, it was discovered that the coordination is enhanced to maintain the efficiency of degradation. The features of entropy and determinant suggest that active proteasomes resist the attack caused by AD like defenders, on the one hand, to protect themselves (entropy reduces), and on the other hand, to fight the enemy (determinant reduces). It is noted that these are results from biocomputing and need to be supported by further biological experiments.
Language	English
Publishing date	2024-01-31
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2452967-9
ISSN	1662-5099
ISSN	1662-5099
DOI	10.3389/fnmol.2023.1330853
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Article: Primary hyperparathyroidism: predictors of sporadic multi-gland disease.

Yang, Lu / Jing, Xingguo / Pang, Hua / Guan, Lili / Li, Mengdan

Endocrine connections

2024 Volume 13, Issue 5

Abstract: In this review, we discuss the definition, prevalence, and etiology of sporadic multiglandular disease (MGD), with an emphasis on its preoperative and intraoperative predictors. Primary hyperparathyroidism (PHPT) is the third-most common endocrine ... ...

Abstract	In this review, we discuss the definition, prevalence, and etiology of sporadic multiglandular disease (MGD), with an emphasis on its preoperative and intraoperative predictors. Primary hyperparathyroidism (PHPT) is the third-most common endocrine disorder, and multiglandular parathyroid disease (MGD) is a cause of PHPT. Hereditary MGD can be definitively diagnosed with detailed family history and genetic testing, whereas sporadic MGD presents a greater challenge in clinical practice, and parathyroidectomy for MGD is associated with a higher risk of surgical failure than single gland disease (SGD). Therefore, it is crucial to be able to predict the presence of sporadic MGD in a timely manner, either preoperatively or intraoperatively. Various predictive methods cannot accurately identify all cases of sporadic MGD, but they can greatly optimize the management of MGD diagnosis and treatment and optimize the cure rate. Future research will urge us to investigate more integrative predictive models as well as increase our understanding of MGD pathogenesis.
Language	English
Publishing date	2024-04-04
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	2668428-7
ISSN	2049-3614
ISSN	2049-3614
DOI	10.1530/EC-23-0492
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Article ; Online: Comparison of Angiolytic Effects Between the 445-nm Blue Laser and 532-nm Pulsed KTP Laser.

Nguyen, Duy Duong / Pang, Jing-Yin / Novakovic, Daniel

The Laryngoscope

2024

Abstract: Objective: This study aimed to compare the selective absorption of the 445-nm Blue laser (BL) and the 532-nm pulsed potassium-titanyl-phosphate (KTP) laser by blood vessels.: Methods: Thirty-six chicken eggs at day 14 of incubation were dissected to ... ...

Abstract	Objective: This study aimed to compare the selective absorption of the 445-nm Blue laser (BL) and the 532-nm pulsed potassium-titanyl-phosphate (KTP) laser by blood vessels. Methods: Thirty-six chicken eggs at day 14 of incubation were dissected to expose the chick chorioallantoic membrane (CAM). Third-order vessels of the CAM were identified and irradiated using BL and KTP lasers using various settings at a laser-to-vessel distance of 3 mm using 0.4 mm fiber size. In total, 494 vessels segments were irradiated. Mean (standard deviation) number of irradiations for each setting was 26.0 (4.6), range from 15 to 39. Outcome measures included ablation rate (AR) and rupture rate (RR). Results: The two lasers were compared for AR and RR at long and medium pulse width (PW) associated with different power levels. At long PW (above 100 ms), BL showed significantly higher AR than KTP at high energy (600 mJ/pulse) and low energy (400 mJ/pulse); they did not show different AR and RR at medium energy levels (500 mJ/pulse). Using medium PW settings plus high and medium energy levels, BL and KTP showed relatively high AR and did not significantly differ in performance. However, at medium PW plus low energy (400-450 mJ/pulse), KTP showed significantly higher AR compared to BL. Conclusion: At long PW, BL appeared to show higher AR than KTP at high or low energy levels, but they showed equivalent performance at medium energy. At medium PW, both performed similarly from high to medium energy, but KTP appeared to perform better than BL at lower energy settings. Level of evidence: NA Laryngoscope, 2024.
Language	English
Publishing date	2024-02-26
Publishing country	United States
Document type	Journal Article
ZDB-ID	80180-x
ISSN	1531-4995 ; 0023-852X
ISSN (online)	1531-4995
ISSN	0023-852X
DOI	10.1002/lary.31364
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Article ; Online: Special clinical features with a novel mutation site of CHN1 gene in a Chinese family with Duane retraction syndrome.

Wang, Minshu / Liu, Jing / Pang, Honglei / Bu, Juan

Strabismus

2024 , Page(s) 1–7

Abstract: Purpose: This study is to describe the special clinical and genotypic features of a Chinese family with variant types of Duane retraction syndrome and to present our experience on managing these cases.: Methods: Four individuals from one family were ... ...

Abstract	Purpose: This study is to describe the special clinical and genotypic features of a Chinese family with variant types of Duane retraction syndrome and to present our experience on managing these cases. Methods: Four individuals from one family were reviewed by ophthalmologic examinations, in which two affected and two unaffected individuals were revealed. MRI scans were performed on the two patients. Relevant gene mutations were screened by the next-generation sequencing technology and confirmed by Sanger sequencing technology. Results: The six-year-old proband presented with special clinical features of severe horizontal gaze dysfunction, exotropia and mild scoliosis. His mother showed significantly limited binocular abductions, with retraction of eyeballs in adduction. From MRI scans, abducens nerves were not observed in both patients and the oculomotor nerve was slightly thin in the proband. The proband and his mother shared the same CHN1 gene mutation site (c. 62A>G; p.Y21C). Strabismus surgery was performed on the proband to correct the primary gaze exotropia.(NM_001822: exon3 or NM_001025201: exon4: c. 62A>G; p.Y21C). Conclusions: A novel CHN1 gene mutation was revealed from a Chinese family with Duane retraction syndrome. Remarkably, the proband and his mother presented different clinical features of ocular motility disorder. Strabismus correction surgery and amblyopia training helped to improve the appearance and visual function of the proband.
Language	English
Publishing date	2024-03-20
Publishing country	England
Document type	Journal Article
ZDB-ID	1149100-0
ISSN	1744-5132 ; 0927-3972
ISSN (online)	1744-5132
ISSN	0927-3972
DOI	10.1080/09273972.2023.2299470
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Article: Acupoint Selection in Postoperative Ophthalmic Pain Management: A Data Mining Protocol.

Wang, Jing / Yang, Feng / Wang, Xing / Pang, Fang

Journal of pain research

2024 Volume 17, Page(s) 903–909

Abstract: Background: Postoperative ophthalmic pain not only induces anxiety and depression among patients, but also prolongs the recovery cycle. However, the management of postoperative pain in ophthalmology is still not standardized. The effectiveness of ... ...

Abstract	Background: Postoperative ophthalmic pain not only induces anxiety and depression among patients, but also prolongs the recovery cycle. However, the management of postoperative pain in ophthalmology is still not standardized. The effectiveness of acupuncture in treating postoperative pain has been validated based on numerous clinical trials and meta-analysis. Our study is to conduct the first data mining analysis to identify the most effective acupoints selection and combinations for treating postoperative ophthalmic pain, inform. Methods: We will search bibliographic databases from inception to November 2023. Clinical trials evaluating the effectiveness of acupuncture therapy in the management of postoperative ophthalmic pain will be selected. Reviews, protocols, animal studies, case reports, systematic evaluations and Meta-analyses will be excluded. Primary outcome indicators will be clinical outcomes related to postoperative ophthalmic pain. Descriptive statistics will be performed in Excel 2019. Association rule analysis will be performed in SPSS Modeler 18.0. Exploratory factor analysis and cluster analysis will be performed in SPSS Statistics 25.0. Results: This study will investigate the most effective point selection and combination of acupuncture points for the treatment of postoperative ophthalmic pain. Conclusion: Our findings will provide evidence for the effectiveness and potential therapeutic prescription of acupuncture for postoperative ophthalmologic pain, helping clinicians and patients work together to make more informed decisions.
Language	English
Publishing date	2024-03-05
Publishing country	New Zealand
Document type	Journal Article
ZDB-ID	2495284-9
ISSN	1178-7090
ISSN	1178-7090
DOI	10.2147/JPR.S449175
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Article ; Online: Sale methods of betel nuts in China: Cash back and low price repurchase.

Pang, Liwei / Kong, Jing

Oral diseases

2022 Volume 29, Issue 5, Page(s) 2324–2325

MeSH term(s)	Humans ; Areca ; Mouth Neoplasms ; China
Language	English
Publishing date	2022-06-23
Publishing country	Denmark
Document type	Letter
ZDB-ID	1290529-x
ISSN	1601-0825 ; 1354-523X
ISSN (online)	1601-0825
ISSN	1354-523X
DOI	10.1111/odi.14250
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