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  1. Article ; Online: Domenico Scafoglio e Simona De Luna, Brigantesse e briganti. Le due metà della banda

    Stefania Mazzega

    Laboratoire Italien (2023)

    2023  

    Keywords Social Sciences ; H
    Language French
    Publishing date 2023-10-01T00:00:00Z
    Publisher École Normale Supérieure de Lyon Editions
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: The Zooxanthellate Jellyfish Holobiont

    De Domenico, Stefania / De Rinaldis, Gianluca / Mammone, Marta / Bosch-Belmar, Mar / Piraino, Stefano / Leone, Antonella

    Marine drugs

    2023  Volume 21, Issue 5

    Abstract: Cassiopea ... ...

    Abstract Cassiopea andromeda
    MeSH term(s) Animals ; Cnidaria ; Scyphozoa/chemistry ; Antioxidants/pharmacology ; Antioxidants/chemistry ; Proteins ; Fatty Acids
    Chemical Substances Antioxidants ; Proteins ; Fatty Acids
    Language English
    Publishing date 2023-04-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2175190-0
    ISSN 1660-3397 ; 1660-3397
    ISSN (online) 1660-3397
    ISSN 1660-3397
    DOI 10.3390/md21050272
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  3. Article ; Online: Correction to: Internal validation study to assess the SeqStudio™ for human identification's performance.

    Soldati, Giulia / Turrina, Stefania / Saccardo, Chiara / Ausania, Francesco / De Leo, Domenico

    International journal of legal medicine

    2023  Volume 137, Issue 6, Page(s) 1943

    Language English
    Publishing date 2023-08-03
    Publishing country Germany
    Document type Published Erratum
    ZDB-ID 1055109-8
    ISSN 1437-1596 ; 0937-9827
    ISSN (online) 1437-1596
    ISSN 0937-9827
    DOI 10.1007/s00414-023-03071-5
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    Un I Zs.312: Show issues Location:
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  4. Article: Combination of Solid State and Submerged Fermentation Strategies to Produce a New Jellyfish-Based Food.

    Ramires, Francesca Anna / Bleve, Gianluca / De Domenico, Stefania / Leone, Antonella

    Foods (Basel, Switzerland)

    2022  Volume 11, Issue 24

    Abstract: This study describes the set-up and optimization of a fermentation strategy applied to a composite raw material containing jellyfish biomass as the principal ingredient. New fermented food was developed by combining fresh ... ...

    Abstract This study describes the set-up and optimization of a fermentation strategy applied to a composite raw material containing jellyfish biomass as the principal ingredient. New fermented food was developed by combining fresh jellyfish
    Language English
    Publishing date 2022-12-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704223-6
    ISSN 2304-8158
    ISSN 2304-8158
    DOI 10.3390/foods11243974
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  5. Article ; Online: Correction: Concordance study on Y-STRs typing between SeqStudio™ genetic analyzer for HID and MiSeq™ FGx forensic genomics system.

    Soldati, Giulia / Turrina, Stefania / Treccani, Mirko / Saccardo, Chiara / Ausania, Francesco / De Leo, Domenico

    Molecular biology reports

    2023  Volume 50, Issue 12, Page(s) 9791

    Language English
    Publishing date 2023-11-10
    Publishing country Netherlands
    Document type Published Erratum
    ZDB-ID 186544-4
    ISSN 1573-4978 ; 0301-4851
    ISSN (online) 1573-4978
    ISSN 0301-4851
    DOI 10.1007/s11033-023-08908-1
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  6. Article ; Online: The ménage à trois of healthcare

    Riccardo Saccà / Rachele Turrini / Francesco Ausania / Stefania Turrina / Domenico De Leo

    Frontiers in Medicine, Vol

    the actors in after-AI era under patient consent

    2024  Volume 10

    Abstract: IntroductionArtificial intelligence has become an increasingly powerful technological instrument in recent years, revolutionizing many sectors, including public health. Its use in this field will inevitably change clinical practice, the patient-caregiver ...

    Abstract IntroductionArtificial intelligence has become an increasingly powerful technological instrument in recent years, revolutionizing many sectors, including public health. Its use in this field will inevitably change clinical practice, the patient-caregiver relationship and the concept of the diagnosis and treatment pathway, affecting the balance between the patient’s right to self-determination and health, and thus leading to an evolution of the concept of informed consent. The aim was to characterize the guidelines for the use of artificial intelligence, its areas of application and the relevant legislation, to propose guiding principles for the design of optimal informed consent for its use.Materials and methodsA classic review by keywords on the main search engines was conducted. An analysis of the guidelines and regulations issued by scientific authorities and legal bodies on the use of artificial intelligence in public health was carried out.ResultsThe current areas of application of this technology were highlighted, divided into sectors, its impact on them, as well as a summary of current guidelines and legislation.DiscussionThe ethical implications of artificial intelligence in the health care system were assessed, particularly regarding the therapeutic alliance between doctor and patient, and the balance between the right to self-determination and health. Finally, given the evolution of informed consent in relation to the use of this new technology, seven guiding principles were proposed to guarantee the right to the most informed consent or dissent.
    Keywords artificial intelligence ; informed consent ; therapeutic alliance ; patient-caregiver relationship ; medical ethics ; patient autonomy ; Medicine (General) ; R5-920
    Subject code 170
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article: The ménage à trois of healthcare: the actors in after-AI era under patient consent.

    Saccà, Riccardo / Turrini, Rachele / Ausania, Francesco / Turrina, Stefania / De Leo, Domenico

    Frontiers in medicine

    2024  Volume 10, Page(s) 1329087

    Abstract: Introduction: Artificial intelligence has become an increasingly powerful technological instrument in recent years, revolutionizing many sectors, including public health. Its use in this field will inevitably change clinical practice, the patient- ... ...

    Abstract Introduction: Artificial intelligence has become an increasingly powerful technological instrument in recent years, revolutionizing many sectors, including public health. Its use in this field will inevitably change clinical practice, the patient-caregiver relationship and the concept of the diagnosis and treatment pathway, affecting the balance between the patient's right to self-determination and health, and thus leading to an evolution of the concept of informed consent. The aim was to characterize the guidelines for the use of artificial intelligence, its areas of application and the relevant legislation, to propose guiding principles for the design of optimal informed consent for its use.
    Materials and methods: A classic review by keywords on the main search engines was conducted. An analysis of the guidelines and regulations issued by scientific authorities and legal bodies on the use of artificial intelligence in public health was carried out.
    Results: The current areas of application of this technology were highlighted, divided into sectors, its impact on them, as well as a summary of current guidelines and legislation.
    Discussion: The ethical implications of artificial intelligence in the health care system were assessed, particularly regarding the therapeutic alliance between doctor and patient, and the balance between the right to self-determination and health. Finally, given the evolution of informed consent in relation to the use of this new technology, seven guiding principles were proposed to guarantee the right to the most informed consent or dissent.
    Language English
    Publishing date 2024-01-08
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2023.1329087
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Resizing reaction volumes for the ForenSeq™ DNA Signature Prep kit library preparation.

    Turrina, Stefania / De Leo, Domenico

    Medicine, science, and the law

    2021  Volume 61, Issue 1_suppl, Page(s) 92–95

    Abstract: The introduction of next generation sequencing (NGS; also known as massively parallel sequencing) technology in the field of forensic genetics has been welcomed by the scientific community, above all because it complements the weaknesses of capillary ... ...

    Abstract The introduction of next generation sequencing (NGS; also known as massively parallel sequencing) technology in the field of forensic genetics has been welcomed by the scientific community, above all because it complements the weaknesses of capillary electrophoresis (CE) in the analysis of genetic markers, such as single nucleotide polymorphism (SNP) typing. However, one of the main obstacles to its adoption does not seem to be the cost of the instrumentation, but rather the cost of the NGS library preparation kits. With the aim of reducing the cost of library preparation without compromising the quality of the results, we tried to scale down reaction volumes for the first two polymerase chain reactions in the amplification and enrichment phases of the targeted loci of library preparation using the ForenSeq™ DNA Signature Prep kit. We used 1 µL templated DNA input to a concentration of 1 ng/µL, instead of the 5 µL at 0.2 ng/µL recommended by the manufacturer. Our findings indicate that reduction of the library preparation volume using the ForenSeq™ DNA Signature Prep kit did not interfere with the quality and reproducibility of the DNA profiles obtained and can help lower the overall cost of NGS.
    MeSH term(s) Forensic Genetics/instrumentation ; Gene Library ; High-Throughput Nucleotide Sequencing/economics ; High-Throughput Nucleotide Sequencing/instrumentation ; Humans ; Polymerase Chain Reaction ; Reproducibility of Results ; Sequence Analysis, DNA/economics ; Sequence Analysis, DNA/instrumentation
    Language English
    Publishing date 2021-02-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 301137-9
    ISSN 2042-1818 ; 0025-8024
    ISSN (online) 2042-1818
    ISSN 0025-8024
    DOI 10.1177/0025802420923163
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 206: Show issues Location:
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  9. Article ; Online: Medical error disclosure in the Italian healthcare context: A delicate balance between ethical obligations and the principle of non-self-incrimination.

    Gibelli, Filippo / Turrina, Stefania / De Leo, Domenico

    Patient education and counseling

    2022  Volume 105, Issue 7, Page(s) 1976–1979

    Abstract: ... of interest, relating to the possible detrimental effects on doctors who accuse themselves of conduct ...

    Abstract Surprisingly, Italian legal doctrine and jurisprudence never systematically address the medical error disclosure issue. The topic of medical error communication represents a non-negligible profile of interest, relating to the possible detrimental effects on doctors who accuse themselves of conduct that does not comply with the lex artis. The effects of error disclosure on the effectiveness of insurance guarantees in civil and administrative liability are particularly relevant, as are the implications for ethical liability. Although the burden of reporting an error falls within the wide range of informative duties doctors hold, it still seems far from having found a factual statement in clinical practice, especially in Italy. This applies whether the error has a marginal or significant impact on the patient's health. The reasons lay in a very contradictory legal framework. Doctors tend with increasing ease not to comply with their information obligation - especially in cases where fulfilling this duty means admitting a personal, professional error - to preserve the integrity of their professional images. This article aims to offer a brief overview of that topic in the context of Italian healthcare.
    MeSH term(s) Communication ; Delivery of Health Care ; Disclosure ; Humans ; Liability, Legal ; Medical Errors ; Morals ; Truth Disclosure
    Language English
    Publishing date 2022-03-09
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 605590-4
    ISSN 1873-5134 ; 0738-3991
    ISSN (online) 1873-5134
    ISSN 0738-3991
    DOI 10.1016/j.pec.2022.03.003
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    Zs.A 1465: Show issues Location:
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  10. Article: An Alum-Free Jellyfish Treatment for Food Applications.

    Bleve, Gianluca / Ramires, Francesca Anna / De Domenico, Stefania / Leone, Antonella

    Frontiers in nutrition

    2021  Volume 8, Page(s) 718798

    Abstract: Jellyfish, marketed and consumed as food in The Far East, are traditionally processed using salt and alum mixtures. In recent years, the interest of Western consumers in jellyfish (JF) as a food source is increasing. In Europe [European Union (EU)], JF- ... ...

    Abstract Jellyfish, marketed and consumed as food in The Far East, are traditionally processed using salt and alum mixtures. In recent years, the interest of Western consumers in jellyfish (JF) as a food source is increasing. In Europe [European Union (EU)], JF-derived food products are regulated by a novel food law, but methods for JF treatment and processing have not been developed yet. In this study, a protocol for the stabilization and processing of JF into semi-finished food products without the use of alum is proposed for the first time. Safety and quality parameters, together with a series of technological and nutritional traits, were used to monitor the proposed process and for the characterization of the JF-derived products. Calcium lactate (E327), calcium citrate (E333), and calcium acetate (E263), which are food thickening/stabilizing agents allowed by EU regulations, were used in order to control the presence of possible microbial pathogens and spoilage species. The use of calcium lactate and citrate led to an increase in texture values (~1.7-1.8-fold higher than in starting raw materials) and in several nutritional traits such as antioxidant activity, and protein and fatty acid content. In particular, the combination of JF treatments with calcium salts and phenolic compounds resulted in an antioxidant activity increase of up to 8-fold, protein concentration increase of up to 2.6-fold, fatty acid composition maintenance, and a ω6/ω3 ratio lower than 1. For the first time, the application of phenolic compounds to improve JF technological and nutritional features was verified. This study proposes a new procedure for JF treatment and stabilization useful for future potential food applications in Western countries.
    Language English
    Publishing date 2021-08-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2776676-7
    ISSN 2296-861X
    ISSN 2296-861X
    DOI 10.3389/fnut.2021.718798
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