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  1. Article: Ticagrelor: clinical development and future potential.

    Sanderson, Nicholas C / Parker, William A E / Storey, Robert F

    Reviews in cardiovascular medicine

    2021  Volume 22, Issue 2, Page(s) 373–394

    Abstract: Platelets participate centrally in atherothrombosis, resulting in vessel occlusion and ischaemia. Consequently, optimisation of antiplatelet regimens has the potential to further reduce the residual burden of morbidity and mortality associated with ... ...

    Abstract Platelets participate centrally in atherothrombosis, resulting in vessel occlusion and ischaemia. Consequently, optimisation of antiplatelet regimens has the potential to further reduce the residual burden of morbidity and mortality associated with atherosclerosis. Ticagrelor is a potent oral platelet P2Y
    MeSH term(s) Aspirin ; Brain Ischemia ; Humans ; Platelet Aggregation Inhibitors/adverse effects ; Stroke ; Ticagrelor/adverse effects
    Chemical Substances Platelet Aggregation Inhibitors ; Ticagrelor (GLH0314RVC) ; Aspirin (R16CO5Y76E)
    Language English
    Publishing date 2021-07-14
    Publishing country Singapore
    Document type Journal Article ; Review
    ZDB-ID 2108910-3
    ISSN 1530-6550
    ISSN 1530-6550
    DOI 10.31083/j.rcm2202044
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6410: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  2. Book: Treatment strategies for patients with psychiatric comorbidity

    Wetzler, Scott / Sanderson, William C.

    (An Einstein psychiatry publication ; 15)

    1997  

    Author's details ed. by Scott Wetzler ; William C. Sanderson
    Series title An Einstein psychiatry publication ; 15
    Einstein psychiatry publication
    Collection Einstein psychiatry publication
    Keywords Mental Disorders / complications ; Mental Disorders / therapy
    Language English
    Size XVI, 368 S., 24 cm
    Publisher Wiley
    Publishing place New York u.a.
    Publishing country United States
    Document type Book
    Note Includes bibliographical references and index
    HBZ-ID HT016449602
    ISBN 0-471-11773-0 ; 978-0-471-11773-5
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2004 A 6125 order for loan Magazin

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  3. Article ; Online: AKAP150-anchored PKA regulates synaptic transmission and plasticity, neuronal excitability and CRF neuromodulation in the mouse lateral habenula.

    Simmons, Sarah C / Flerlage, William J / Langlois, Ludovic D / Shepard, Ryan D / Bouslog, Christopher / Thomas, Emily H / Gouty, Kaitlyn M / Sanderson, Jennifer L / Gouty, Shawn / Cox, Brian M / Dell'Acqua, Mark L / Nugent, Fereshteh S

    Communications biology

    2024  Volume 7, Issue 1, Page(s) 345

    Abstract: The scaffolding A-kinase anchoring protein 150 (AKAP150) is critically involved in kinase and phosphatase regulation of synaptic transmission/plasticity, and neuronal excitability. Emerging evidence also suggests that AKAP150 signaling may play a key ... ...

    Abstract The scaffolding A-kinase anchoring protein 150 (AKAP150) is critically involved in kinase and phosphatase regulation of synaptic transmission/plasticity, and neuronal excitability. Emerging evidence also suggests that AKAP150 signaling may play a key role in brain's processing of rewarding/aversive experiences, however its role in the lateral habenula (LHb, as an important brain reward circuitry) is completely unknown. Using whole cell patch clamp recordings in LHb of male wildtype and ΔPKA knockin mice (with deficiency in AKAP-anchoring of PKA), here we show that the genetic disruption of PKA anchoring to AKAP150 significantly reduces AMPA receptor-mediated glutamatergic transmission and prevents the induction of presynaptic endocannabinoid-mediated long-term depression in LHb neurons. Moreover, ΔPKA mutation potentiates GABA
    MeSH term(s) Animals ; Male ; Mice ; A Kinase Anchor Proteins/genetics ; A Kinase Anchor Proteins/metabolism ; Corticotropin-Releasing Hormone/metabolism ; Endocannabinoids ; Habenula/metabolism ; Neuronal Plasticity/physiology ; Neurons/physiology ; Receptors, AMPA/genetics ; Receptors, AMPA/metabolism ; Receptors, GABA-A/metabolism ; Synaptic Transmission/physiology
    Chemical Substances A Kinase Anchor Proteins ; Corticotropin-Releasing Hormone (9015-71-8) ; Endocannabinoids ; Receptors, AMPA ; Receptors, GABA-A ; Akap5 protein, mouse
    Language English
    Publishing date 2024-03-20
    Publishing country England
    Document type Journal Article
    ISSN 2399-3642
    ISSN (online) 2399-3642
    DOI 10.1038/s42003-024-06041-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book: Treating generalized anxiety disorder

    Rygh, Jayne L. / Sanderson, William C.

    evidence-based strategies, tools, and techniques

    2004  

    Author's details Jayne L. Rygh and William C. Sanderson
    Keywords Anxiety Disorders / therapy ; Cognitive Therapy / methods ; Evidence-Based Medicine
    Language English
    Size XIII, 210 S. : Ill.
    Publisher Guilford Press
    Publishing place New York u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT014251201
    ISBN 1-59385-039-5 ; 978-1-59385-039-5
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2005 A 2947 order for loan Magazin

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  5. Article ; Online: Rotational fishing enables biodiversity recovery and provides a model for oyster (Ostrea edulis) habitat restoration.

    Kennon, Naomi A / Robertson-Jones, Alexander / Jemmett, Sebastian / Hugh-Jones, Tristan / Bell, Michael C / Sanderson, William G

    PloS one

    2023  Volume 18, Issue 3, Page(s) e0283345

    Abstract: Reefs formed by Ostrea edulis, the European native oyster, are among many biogenic habitats that have declined globally. European oyster habitats are now rare, and undisturbed examples have not been described. As more is understood of the ecosystem ... ...

    Abstract Reefs formed by Ostrea edulis, the European native oyster, are among many biogenic habitats that have declined globally. European oyster habitats are now rare, and undisturbed examples have not been described. As more is understood of the ecosystem services provided by the reefs, oyster restoration efforts are on the rise, becoming a more prominent component of Europe's portfolio of marine conservation practices. It is therefore important to establish the relationship between the development of oyster reefs and their associated biotic community if the biodiversity benefits are to be accurately predicted and the progress of restoration projects assessed. The Loch Ryan oyster fishery in Southwest Scotland is the last of its type and uses a rotational harvest system where different areas are fished each year and then left for six years before they are fished again. This provided an opportunity to study the effect of oyster reef development and biodiversity gain at different stages of habitat recovery. In this study three treatments were surveyed for faunal biodiversity, oyster shell density and oyster shell percentage cover. Treatments were plots that had been harvested one year before, two years before, and six years before the study. The treatments were surveyed with SCUBA using a combination of video transects and photo quadrats. Oyster shell density, oyster shell percent cover and macrofaunal biodiversity differed significantly between treatments, with the highest values observed in the six-year treatment. Shell density was 8.5 times higher in the six-year treatment compared to the one-year treatment, whilst Shannon-Wiener's diversity was 60.5% higher, and Margalef's richness 68.8% higher. Shell density and percent cover had a significant positive relationship with macrofaunal biodiversity. This is probably due to the provision of increased structural complexity in the matrix of live and dead oyster shells. Projecting forward the trend of biodiversity increase in relation to time since disturbance indicates that full recovery would take approximately ten years in which time diversity (Shannon-Wiener) would probably have doubled. The findings from the present study indicate the probable biodiversity benefits of oyster habitat restoration and a cost-effective metric (shell density) to judge progress in restoration projects.
    MeSH term(s) Animals ; Ecosystem ; Ostrea ; Hunting ; Conservation of Natural Resources ; Biodiversity
    Language English
    Publishing date 2023-03-29
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0283345
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Rotational fishing enables biodiversity recovery and provides a model for oyster (Ostrea edulis) habitat restoration

    Naomi A. Kennon / Alexander Robertson-Jones / Sebastian Jemmett / Tristan Hugh-Jones / Michael C. Bell / William G. Sanderson

    PLoS ONE, Vol 18, Iss

    2023  Volume 3

    Abstract: Reefs formed by Ostrea edulis, the European native oyster, are among many biogenic habitats that have declined globally. European oyster habitats are now rare, and undisturbed examples have not been described. As more is understood of the ecosystem ... ...

    Abstract Reefs formed by Ostrea edulis, the European native oyster, are among many biogenic habitats that have declined globally. European oyster habitats are now rare, and undisturbed examples have not been described. As more is understood of the ecosystem services provided by the reefs, oyster restoration efforts are on the rise, becoming a more prominent component of Europe’s portfolio of marine conservation practices. It is therefore important to establish the relationship between the development of oyster reefs and their associated biotic community if the biodiversity benefits are to be accurately predicted and the progress of restoration projects assessed. The Loch Ryan oyster fishery in Southwest Scotland is the last of its type and uses a rotational harvest system where different areas are fished each year and then left for six years before they are fished again. This provided an opportunity to study the effect of oyster reef development and biodiversity gain at different stages of habitat recovery. In this study three treatments were surveyed for faunal biodiversity, oyster shell density and oyster shell percentage cover. Treatments were plots that had been harvested one year before, two years before, and six years before the study. The treatments were surveyed with SCUBA using a combination of video transects and photo quadrats. Oyster shell density, oyster shell percent cover and macrofaunal biodiversity differed significantly between treatments, with the highest values observed in the six-year treatment. Shell density was 8.5 times higher in the six-year treatment compared to the one-year treatment, whilst Shannon-Wiener’s diversity was 60.5% higher, and Margalef’s richness 68.8% higher. Shell density and percent cover had a significant positive relationship with macrofaunal biodiversity. This is probably due to the provision of increased structural complexity in the matrix of live and dead oyster shells. Projecting forward the trend of biodiversity increase in relation to time since disturbance indicates ...
    Keywords Medicine ; R ; Science ; Q
    Subject code 333
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Rotational fishing enables biodiversity recovery and provides a model for oyster (Ostrea edulis) habitat restoration.

    Naomi A Kennon / Alexander Robertson-Jones / Sebastian Jemmett / Tristan Hugh-Jones / Michael C Bell / William G Sanderson

    PLoS ONE, Vol 18, Iss 3, p e

    2023  Volume 0283345

    Abstract: Reefs formed by Ostrea edulis, the European native oyster, are among many biogenic habitats that have declined globally. European oyster habitats are now rare, and undisturbed examples have not been described. As more is understood of the ecosystem ... ...

    Abstract Reefs formed by Ostrea edulis, the European native oyster, are among many biogenic habitats that have declined globally. European oyster habitats are now rare, and undisturbed examples have not been described. As more is understood of the ecosystem services provided by the reefs, oyster restoration efforts are on the rise, becoming a more prominent component of Europe's portfolio of marine conservation practices. It is therefore important to establish the relationship between the development of oyster reefs and their associated biotic community if the biodiversity benefits are to be accurately predicted and the progress of restoration projects assessed. The Loch Ryan oyster fishery in Southwest Scotland is the last of its type and uses a rotational harvest system where different areas are fished each year and then left for six years before they are fished again. This provided an opportunity to study the effect of oyster reef development and biodiversity gain at different stages of habitat recovery. In this study three treatments were surveyed for faunal biodiversity, oyster shell density and oyster shell percentage cover. Treatments were plots that had been harvested one year before, two years before, and six years before the study. The treatments were surveyed with SCUBA using a combination of video transects and photo quadrats. Oyster shell density, oyster shell percent cover and macrofaunal biodiversity differed significantly between treatments, with the highest values observed in the six-year treatment. Shell density was 8.5 times higher in the six-year treatment compared to the one-year treatment, whilst Shannon-Wiener's diversity was 60.5% higher, and Margalef's richness 68.8% higher. Shell density and percent cover had a significant positive relationship with macrofaunal biodiversity. This is probably due to the provision of increased structural complexity in the matrix of live and dead oyster shells. Projecting forward the trend of biodiversity increase in relation to time since disturbance indicates ...
    Keywords Medicine ; R ; Science ; Q
    Subject code 333
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  8. Book: Marital distress

    Rathus, Jill H. / Sanderson, William C.

    cognitive behavioral interventions for couples

    (Clinical application of evidence-based psychotherapy)

    1999  

    Author's details Jill H. Rathus ; William C. Sanderson
    Series title Clinical application of evidence-based psychotherapy
    Language English
    Size XI, 378 S.
    Publisher Aronson
    Publishing place Northvale, NJ
    Publishing country United States
    Document type Book
    HBZ-ID HT011233475
    ISBN 0-7657-0000-X ; 978-0-7657-0000-1
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2000 A 1743 order for loan Magazin

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  9. Book: Treatment of obsessive compulsive disorder

    MacGinn, Lata K. / Sanderson, William C.

    (Clinical application of evidence-based psychotherapy)

    1999  

    Author's details Lata K. McGinn & William C. Sanderson
    Series title Clinical application of evidence-based psychotherapy
    Keywords Zwangsstörung ; Therapie
    Subject Medizinische Behandlung ; Behandlung ; Krankenbehandlung ; Anankastische Neurose ; Anankastisches Syndrom ; Obsessionsneurose ; Zwangssyndrom ; Zwangskrankheit ; Zwangserkrankung ; Zwangserscheinung ; Zwangsneurose
    Language English
    Size XIV, 296 S.
    Publisher Aronson
    Publishing place Northvale, NJ u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT011223328
    ISBN 0-7657-0211-8 ; 978-0-7657-0211-1
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2000 A 2520 order for loan Magazin

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  10. Book: Specific phobias

    Bruce, Timothy J. / Sanderson, William C.

    clinical applications of evidence-based psychotherapy

    (Clinical application of evidence-based psychotherapy)

    1998  

    Author's details Timothy J. Bruce ; William C. Sanderson
    Series title Clinical application of evidence-based psychotherapy
    Keywords Phobic Disorders / therapy ; Phobic Disorders / psychology ; Behavior Therapy / methods ; Evidence-Based Medicine
    Language English
    Size XIV, 264 S.
    Publisher Aronson
    Publishing place Northvale, NJ u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT009852616
    ISBN 1-56821-883-4 ; 978-1-56821-883-0
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1999 A 1078 order for loan Magazin

    Order via subito

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