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  1. Article: Memoir of Walter S. Cornell 1877-1969.

    Cornell, H W

    Transactions & studies of the College of Physicians of Philadelphia

    1970  Volume 37, Issue 3, Page(s) 257–258

    MeSH term(s) History, 20th Century ; Pennsylvania ; School Health Services/history ; United States
    Language English
    Publishing date 1970-01
    Publishing country United States
    Document type Biography ; Historical Article ; Journal Article
    ZDB-ID 208414-4
    ISSN 0010-1087 ; 0093-2949
    ISSN 0010-1087 ; 0093-2949
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: The Nurse as a Municipal Officer.

    Cornell, Walter S

    The Psychological clinic

    2017  Volume 4, Issue 7, Page(s) 181–188

    Language English
    Publishing date 2017-09-14
    Publishing country United States
    Document type Journal Article
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: The Relation of Physical to Mental Defect in School Children.

    Cornell, Walter S

    The Psychological clinic

    2017  Volume 1, Issue 8, Page(s) 231–234

    Language English
    Publishing date 2017-09-14
    Publishing country United States
    Document type Journal Article
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: The Need of Improved Records of the Physical Condition of School Children.

    Cornell, Walter S

    The Psychological clinic

    2017  Volume 3, Issue 6, Page(s) 161–163

    Language English
    Publishing date 2017-09-14
    Publishing country United States
    Document type Journal Article
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: The Physical Condition of the School Children of the School of Observation, University of Pennsylvania.

    Cornell, Walter S

    The Psychological clinic

    2017  Volume 3, Issue 5, Page(s) 134–135

    Language English
    Publishing date 2017-09-14
    Publishing country United States
    Document type Journal Article
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Age per Grade of Truant and Difficult School Boys.

    Cornell, Walter S

    The Psychological clinic

    2017  Volume 4, Issue 8, Page(s) 239–240

    Language English
    Publishing date 2017-09-14
    Publishing country United States
    Document type Journal Article
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Mentally Defective Children in the Public Schools.

    Cornell, Walter S

    The Psychological clinic

    2017  Volume 2, Issue 3, Page(s) 75–86

    Language English
    Publishing date 2017-09-14
    Publishing country United States
    Document type Journal Article
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: The Nervous Disorders of School Children.

    Cornell, Walter S

    The Psychological clinic

    2017  Volume 4, Issue 3, Page(s) 65–78

    Language English
    Publishing date 2017-09-14
    Publishing country United States
    Document type Journal Article
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Progressive decline of function in renal allografts with normal 1-year biopsies: Gene expression studies fail to identify a classifier.

    Park, Walter D / Kim, Dean Y / Mai, Martin L / Reddy, Kunam S / Gonwa, Thomas / Ryan, Margaret S / Herrera Hernandez, Loren P / Smith, Maxwell L / Geiger, Xochiquetzal J / Turkevi-Nagy, Sandor / Cornell, Lynn D / Smith, Byron H / Kremers, Walter K / Stegall, Mark D

    Clinical transplantation

    2021  Volume 35, Issue 12, Page(s) e14456

    Abstract: Histologic findings on 1-year biopsies such as inflammation with fibrosis and transplant glomerulopathy predict renal allograft loss by 5 years. However, almost half of the patients with graft loss have a 1-year biopsy that is either normal or has only ... ...

    Abstract Histologic findings on 1-year biopsies such as inflammation with fibrosis and transplant glomerulopathy predict renal allograft loss by 5 years. However, almost half of the patients with graft loss have a 1-year biopsy that is either normal or has only interstitial fibrosis. The goal of this study was to determine if there was a gene expression profile in these relatively normal 1-year biopsies that predicted subsequent decline in renal function. Using transcriptome microarrays we measured intragraft mRNA levels in a retrospective Discovery cohort (170 patients with a normal/minimal fibrosis 1-year biopsy, 54 with progressive decline in function/graft loss and 116 with stable function) and developed a nested 10-fold cross-validated gene classifier that predicted progressive decline in renal function (positive predictive value = 38 ± 34%%; negative predictive value = 73 ± 30%, c-statistic = .59). In a prospective, multicenter Validation cohort (270 patients with Normal/Interstitial Fibrosis [IF]), the classifier had a 20% positive predictive value, 85% negative predictive value and .58 c-statistic. Importantly, the majority of patients with graft loss in the prospective study had 1-year biopsies scored as Normal or IF. We conclude predicting graft loss in many renal allograft recipients (i.e., those with a relatively normal 1-year biopsy and eGFR > 40) remains difficult.
    MeSH term(s) Allografts ; Biopsy ; Fibrosis ; Gene Expression ; Glomerular Filtration Rate ; Graft Rejection/etiology ; Graft Rejection/genetics ; Humans ; Kidney/pathology ; Kidney/physiology ; Kidney Transplantation/adverse effects ; Prospective Studies ; Retrospective Studies
    Language English
    Publishing date 2021-11-09
    Publishing country Denmark
    Document type Journal Article ; Multicenter Study ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 639001-8
    ISSN 1399-0012 ; 0902-0063
    ISSN (online) 1399-0012
    ISSN 0902-0063
    DOI 10.1111/ctr.14456
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Global glomerulosclerosis with nephrotic syndrome; the clinical importance of age adjustment.

    Hommos, Musab S / Zeng, Caihong / Liu, Zhihong / Troost, Jonathan P / Rosenberg, Avi Z / Palmer, Matthew / Kremers, Walter K / Cornell, Lynn D / Fervenza, Fernando C / Barisoni, Laura / Rule, Andrew D

    Kidney international

    2017  Volume 93, Issue 5, Page(s) 1175–1182

    Abstract: Globally sclerotic glomeruli (GSG) occur with both normal aging and kidney disease. However, it is unknown whether any GSG or only GSG exceeding that expected for age is clinically important. To evaluate this, we identified patients with a glomerulopathy ...

    Abstract Globally sclerotic glomeruli (GSG) occur with both normal aging and kidney disease. However, it is unknown whether any GSG or only GSG exceeding that expected for age is clinically important. To evaluate this, we identified patients with a glomerulopathy that often presents with nephrotic syndrome (focal segmental glomerulosclerosis, membranous nephropathy, or minimal change disease) in the setting of the Nephrotic Syndrome Study Network (NEPTUNE), China-Digital Kidney Pathology (DiKiP), and the Southeast Minnesota cohorts. Age-based thresholds (95th percentile) for GSG based on normotensive living kidney donors were used to classify each patient into one of three groups; no GSG, GSG normal for age, or GSG abnormal for age. The risk of end-stage renal disease or a 40% decline in glomerular filtration rate during follow-up was then compared between groups. Among the 425 patients studied, 170 had no GSG, 107 had GSG normal for age, and 148 had GSG abnormal for age. Compared to those with no GSG, the risk of kidney disease progression with GSG normal for age was similar but was significantly higher with GSG abnormal for age. This increased risk with GSG abnormal for age remained significant after adjustment for interstitial fibrosis, arteriosclerosis, age, hypertension, diabetes, body mass index, glomerulopathy type, glomerular filtration rate, and proteinuria. Thus, in patients with glomerulopathy that often presents with nephrotic syndrome, global glomerulosclerosis is clinically important only if it exceeds that expected for age.
    MeSH term(s) Adolescent ; Adult ; Age Distribution ; Age Factors ; Aged ; Biopsy ; China/epidemiology ; Disease Progression ; Female ; Glomerular Filtration Rate ; Glomerulonephritis, Membranous/diagnosis ; Glomerulonephritis, Membranous/epidemiology ; Glomerulonephritis, Membranous/physiopathology ; Glomerulosclerosis, Focal Segmental/diagnosis ; Glomerulosclerosis, Focal Segmental/epidemiology ; Glomerulosclerosis, Focal Segmental/physiopathology ; Humans ; Incidence ; Kidney/pathology ; Kidney/physiopathology ; Kidney Failure, Chronic/diagnosis ; Kidney Failure, Chronic/epidemiology ; Kidney Failure, Chronic/physiopathology ; Male ; Middle Aged ; Nephrosis, Lipoid/diagnosis ; Nephrosis, Lipoid/epidemiology ; Nephrosis, Lipoid/physiopathology ; Nephrotic Syndrome/diagnosis ; Nephrotic Syndrome/epidemiology ; Nephrotic Syndrome/physiopathology ; North America/epidemiology ; Prognosis ; Risk Factors ; Time Factors ; Young Adult
    Language English
    Publishing date 2017-12-19
    Publishing country United States
    Document type Comparative Study ; Journal Article ; Multicenter Study ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 120573-0
    ISSN 1523-1755 ; 0085-2538
    ISSN (online) 1523-1755
    ISSN 0085-2538
    DOI 10.1016/j.kint.2017.09.028
    Database MEDical Literature Analysis and Retrieval System OnLINE

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