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Article ; Online: Plant tRNA functions beyond their major role in translation.

Chery, Marjorie / Drouard, Laurence

2022 Volume 74, Issue 7, Page(s) 2352–2363

Abstract: Transfer RNAs (tRNAs) are well known for their essential function as adapters in delivering amino acids to ribosomes and making the link between mRNA and protein according to the genetic code. Besides this central role in protein synthesis, other ... ...

Abstract	Transfer RNAs (tRNAs) are well known for their essential function as adapters in delivering amino acids to ribosomes and making the link between mRNA and protein according to the genetic code. Besides this central role in protein synthesis, other functions are attributed to these macromolecules, or their genes, in all living organisms. This review focuses on these extra functions of tRNAs in photosynthetic organisms. For example, tRNAs are implicated in tetrapyrrole biosynthesis, mRNA stabilization or transport, and priming the reverse transcription of viral RNAs, and tRNA-like structures play important roles in RNA viral genomes. Another important function of tRNAs in regulating gene expression is related to their cleavage allowing the production of small non-coding RNAs termed tRNA-derived RNAs. Here, we examine in more detail the biogenesis of tRNA-derived RNAs and their emerging functions in plants.
MeSH term(s)	RNA, Transfer/genetics ; RNA, Transfer/chemistry ; RNA, Transfer/metabolism ; Genetic Code ; Amino Acids/genetics ; Ribosomes/genetics ; Ribosomes/metabolism ; RNA, Messenger
Chemical Substances	RNA, Transfer (9014-25-9) ; Amino Acids ; RNA, Messenger
Language	English
Publishing date	2022-12-07
Publishing country	England
Document type	Review ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2976-2
ISSN	1460-2431 ; 0022-0957
ISSN (online)	1460-2431
ISSN	0022-0957
DOI	10.1093/jxb/erac483
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Article ; Online: Patient and health worker perspectives on quality of HIV care and treatment services in Haiti.

Puttkammer, Nancy / Demes, Joseph Adrien Emmanuel / Dervis, Witson / Chéry, Jean Marcxime / Elusdort, Josette / Haight, Elizabeth / Honoré, Jean Guy / Simoni, Jane M

BMC health services research

2023 Volume 23, Issue 1, Page(s) 66

Abstract: Background: Poor quality of care is a barrier to engagement in HIV care and treatment in low- and middle-income country settings. This study involved focus group discussions (FGD) with patients and health workers in two large urban hospitals to describe ...

Abstract	Background: Poor quality of care is a barrier to engagement in HIV care and treatment in low- and middle-income country settings. This study involved focus group discussions (FGD) with patients and health workers in two large urban hospitals to describe quality of patient education and psychosocial support services within Haiti's national HIV antiretroviral therapy (ART) program. The purpose of this qualitative study was to illuminate key gaps and salient "ingredients" for improving quality of care. Methods: The study included 8 FGDs with a total of 26 male patients and 32 female patients and 15 smaller FGDs with 57 health workers. The analysis used a directed content analysis method, with the goal of extending existing conceptual frameworks on quality of care through rich description. Results: Dimension of safety, patient-centeredness, accessibility, and equity were most salient. Patients noted risks to privacy with both clinic and community-based services as well as concerns with ART side effects, while health workers described risks to their own safety in providing community-based services. While patients cited examples of positive interactions with health workers that centered their needs and perspectives, they also noted concerns that inhibited trust and satisfaction with services. Health workers described difficult working conditions that challenged their ability to provide patient-centered services. Patients sought favored relationships with health workers to help them navigate the health care system, but this undermined the sense of fairness. Both patients and health workers described frustration with lack of resources to assist patients in dire poverty, and health workers described great pressure to help patients from their "own pockets." Conclusions: These concerns reflected the embeddedness of patient - provider interactions within a health system marked by scarcity, power dynamics between patients and health workers, and social stigma related to HIV. Reinforcing a respectful and welcoming atmosphere, timely service, privacy protection, and building patient perception of fairness in access to support could help to build patient satisfaction and care engagement in Haiti. Improving working conditions for health workers is also critical to achieving quality.
MeSH term(s)	Humans ; Male ; Female ; Haiti ; Qualitative Research ; Focus Groups ; Patient Satisfaction ; HIV Infections/drug therapy ; HIV Infections/psychology
Language	English
Publishing date	2023-01-23
Publishing country	England
Document type	Journal Article
ZDB-ID	2050434-2
ISSN	1472-6963 ; 1472-6963
ISSN (online)	1472-6963
ISSN	1472-6963
DOI	10.1186/s12913-023-09041-2
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Article ; Online: The association of body mass index with tumor aggression among men undergoing radical prostatectomy.

Gregg, Justin R / Magill, Resa / Fang, Andrew M / Chapin, Brian F / Davis, John W / Adibi, Mehrad / Chéry, Lisly / Papadopoulos, John / Pettaway, Curtis / Pisters, Louis / Ward, John F / Hahn, Andrew W / Daniel, Carrie R / Bhaskaran, Jerusha / Zhu, Keyi / Guerrero, Mireya / Zhang, Miao / Troncoso, Patricia

Urologic oncology

2024 Volume 42, Issue 4, Page(s) 116.e1–116.e7

Abstract: Objectives: To evaluate the association of preoperative body mass index (BMI) on adverse pathology in peripheral (PZ) and transition zone (TZ) tumors at time of prostatectomy for localized prostate cancer.: Methods: Clinical and pathologic ... ...

Abstract	Objectives: To evaluate the association of preoperative body mass index (BMI) on adverse pathology in peripheral (PZ) and transition zone (TZ) tumors at time of prostatectomy for localized prostate cancer. Methods: Clinical and pathologic characteristics were obtained from up to 100 consecutive prostatectomy patients from 10 prostate surgeons. BMI groups included normal (18.5-24.9), overweight (25-29.9) and obese (> 29.9). "Aggressive" pathology was defined as the presence of Grade Group (GG) 3 or higher and/or pT3a or higher. Pathologic characteristics were evaluated for association with BMI using univariate analyses. Our primary outcome was the association of BMI with adverse pathology, which was assessed using logistic regression accounting for patient age. We hypothesized that obese BMI would be associated with aggressive TZ tumor. Results: Among 923 patients, 140 (15%) were classified as "normal" BMI, 413 (45%) were "overweight", and 370 (40%) were "obese." 474 patients (51%) had aggressive PZ tumors while 102 (11%) had aggressive TZ tumors. "Obese" BMI was not associated with aggressive TZ tumor compared to normal weight. Increasing BMI group was associated with overall increased risk of aggressive PZ tumor (HR 1.56 [95CI 1.04-2.34]; P = 0.03). Among patients with GG1 or GG2, increasing BMI was associated with presence of pT3a or higher TZ tumor (P = 0.03). Conclusions: Increased BMI is associated with adverse pathology in PZ tumors. TZ adverse pathology risk may be increased among obese men with GG1 or GG2 disease, which has implications for future studies assessing behavioral change among men whose tumors are actively monitored.
MeSH term(s)	Male ; Humans ; Prostate/pathology ; Body Mass Index ; Aggression ; Retrospective Studies ; Prostatic Neoplasms/complications ; Prostatic Neoplasms/surgery ; Prostatic Neoplasms/pathology ; Prostatectomy ; Obesity/complications ; Overweight
Language	English
Publishing date	2024-01-22
Publishing country	United States
Document type	Journal Article
ZDB-ID	1336505-8
ISSN	1873-2496 ; 1078-1439
ISSN (online)	1873-2496
ISSN	1078-1439
DOI	10.1016/j.urolonc.2023.12.013
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Article ; Online: Comparison of Cavity Preparation Times Using Conventional High-Speed Handpiece Versus Er, Cr:YSGG Laser: A Pilot Study with Pediatric Dental Residents.

Chery, Jerry / Freitas, Vanessa / Saman, Daniel M / Gupta, Apeksha

Pediatric dentistry

2022 Volume 44, Issue 2, Page(s) 90–94

Abstract: Purpose: The purpose of this study was to compare pediatric dental residents' comfort levels and cavity preparation time using an Er, Cr:YSGG laser versus a conventional high-speed handpiece.: Methods: This cross-sectional study was conducted on ... ...

Abstract	Purpose: The purpose of this study was to compare pediatric dental residents' comfort levels and cavity preparation time using an Er, Cr:YSGG laser versus a conventional high-speed handpiece. Methods: This cross-sectional study was conducted on residents with no past restorative dental laser experience. A mixed-effects model was used to evaluate the difference in total time and comfort level between the laser and high-speed handpiece groups. Results: A total of 131 teeth (high-speed handpiece group equals 79; laser group equals 52) were completed. The adjusted result showed that the estimated average difference in preparation time among the laser group was 1.92 minutes longer per tooth compared to the high-speed handpiece group. Similarly, when using a laser, residents had a 0.74 times lower rate of comfort compared to the high-speed handpiece group. Conclusions: The total preparation time required for restorative treatment with a laser was significantly higher than the total time with a high-speed handpiece. Additionally, the comfort level was also lower using a laser compared to a high-speed preparation.
MeSH term(s)	Child ; Cross-Sectional Studies ; Dental Cavity Preparation ; Humans ; Lasers, Solid-State/therapeutic use ; Pilot Projects
Language	English
Publishing date	2022-04-28
Publishing country	United States
Document type	Journal Article
ZDB-ID	604709-9
ISSN	1942-5473 ; 0164-1263
ISSN (online)	1942-5473
ISSN	0164-1263
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Article ; Online: The Situated Information, Motivation, and Behavioral Skills Model of HIV Antiretroviral Therapy Adherence Among Persons Living With HIV in Haiti: A Qualitative Study Incorporating Culture and Context.

Puttkammer, Nancy / Emmanuel Demes, Joseph Adrien / Dervis, Witson / Chéry, Jean Marcxime / Elusdort, Josette / Haight, Elizabeth / Balan, Jean Gabriel / Simoni, Jane M

The Journal of the Association of Nurses in AIDS Care : JANAC

2022 Volume 33, Issue 4, Page(s) 448–458

Abstract: Abstract: To inform a clinic-based adherence-promotion intervention, this qualitative study applied the Situated Information, Motivation, and Behavioral Skills Model of Care Initiation and Maintenance to elucidate cultural and contextual factors ... ...

Abstract	Abstract: To inform a clinic-based adherence-promotion intervention, this qualitative study applied the Situated Information, Motivation, and Behavioral Skills Model of Care Initiation and Maintenance to elucidate cultural and contextual factors affecting antiretroviral therapy adherence in Haiti. From the 23 focus group discussions with patients ( n = 58) and health care workers ( n = 57), culturally specific themes emerged relating to Information (e.g., conflicts with allopathic medicine and heuristics about how treatment failure occurs), Motivation (e.g., protecting family members, health and physical appearance, material advantages, and relationships with health workers), and Behavioral Skills (e.g., managing food intake and side effects, navigating health services utilization, accessing medication, and advocating for care needs). Recommendations include: provide therapeutic education on HIV drug resistance; promote the concept of "undetectable = untransmittable"; develop treatment buddy relationships; invest in training and enforcement of patient privacy, transparency, and fairness in access to services and resources; and provide patient-centered behavioral skills counseling.
MeSH term(s)	Anti-HIV Agents/therapeutic use ; Anti-Retroviral Agents/therapeutic use ; HIV Infections/psychology ; Haiti ; Humans ; Medication Adherence/psychology ; Motivation ; Patient Compliance
Chemical Substances	Anti-HIV Agents ; Anti-Retroviral Agents
Language	English
Publishing date	2022-03-01
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	1159376-3
ISSN	1552-6917 ; 1055-3290
ISSN (online)	1552-6917
ISSN	1055-3290
DOI	10.1097/JNC.0000000000000329
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Zs.A 3748: Show issues

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Article ; Online: The Effect of Disability and Social Determinants of Health on Breast and Cervical Cancer Screenings During the COVID-19 Pandemic.

Rolle, LaShae D / Chery, Maurice J / Larson, Michaela / Lopez-Pentecost, Melissa / Calfa, Carmen J / Schlumbrecht, Matthew P / Crane, Tracy E

Preventing chronic disease

2024 Volume 21, Page(s) E05

Abstract: Introduction: The objective of this study was to examine the effect of disability status and social determinants of health (SDOH) on adherence to breast and cervical cancer screening recommendations during the COVID-19 pandemic.: Methods: We ... ...

Abstract	Introduction: The objective of this study was to examine the effect of disability status and social determinants of health (SDOH) on adherence to breast and cervical cancer screening recommendations during the COVID-19 pandemic. Methods: We conducted a secondary analysis of the 2018 and 2020 Behavioral Risk Factor Surveillance System (BRFSS) data sets. We defined adherence to screenings according to the US Preventive Services Task Force guidelines for breast and cervical cancer screening. The analysis included respondents assigned female at birth, aged 50 to 74 years (breast cancer screening) or aged 21 to 65 years (cervical cancer screening). We performed logistic regression to evaluate breast and cervical cancer screening adherence, by disability status and SDOH (health insurance coverage, marital status, and urban residency), independently and simultaneously. Results: Our analysis included 27,526 BRFSS respondents in 2018 and 2020. In 2018, women with disabilities had lower adjusted odds than women without disabilities of being up to date with mammograms (adjusted odds ratio [AOR] = 0.76, 95% CI, 0.63-0.93) and Pap (Papanicolaou) tests (AOR = 0.73; 95% CI, 0.59-0.89). In 2020, among women with disabilities, the adjusted odds of mammogram and Pap test adherence decreased (AOR = 0.69; 95% CI, 0.54-0.89; AOR = 0.59; 95% CI, 0.47-0.75, respectively). In 2018, the adjusted odds of mammogram adherence among rural residents with and without disabilities were 0.83 (95% CI, 0.70-0.98), which decreased to 0.76 (95% CI, 0.62-0.93) in 2020. Conclusion: The findings of this study highlight the effect of disability status and SDOH on breast and cervical cancer screening rates during the COVID-19 pandemic. Public health strategies that acknowledge and address these disparities are crucial in preparing for future public health crises.
MeSH term(s)	Infant, Newborn ; Female ; Humans ; Early Detection of Cancer ; Uterine Cervical Neoplasms/diagnosis ; Uterine Cervical Neoplasms/prevention & control ; Social Determinants of Health ; Pandemics/prevention & control ; COVID-19/diagnosis ; COVID-19/epidemiology ; Breast Neoplasms/diagnosis ; Breast Neoplasms/prevention & control ; Mammography ; Papanicolaou Test ; Disabled Persons ; Mass Screening
Language	English
Publishing date	2024-01-25
Publishing country	United States
Document type	Journal Article
ZDB-ID	2135684-1
ISSN	1545-1151 ; 1545-1151
ISSN (online)	1545-1151
ISSN	1545-1151
DOI	10.5888/pcd21.230234
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Article ; Online: Validity and Reliability of the Load-Velocity Relationship to Predict the One-Repetition Maximum in Deadlift.

Ruf, Ludwig / Chéry, Clément / Taylor, Kristie-Lee

Journal of strength and conditioning research

2018 Volume 32, Issue 3, Page(s) 681–689

Abstract: ... trials (ES = -0.30, 90% CL [-0.78 to 0.17], TE = 0.029 m·s [0.022-0.047], ICC = 0.63 [0.19-0.86], and CV ...

Abstract	Ruf, L, Chéry, C, Taylor, KL. Validity and reliability of the load-velocity relationship to predict the 1RM in deadlift. J Strength Cond Res 32(3): 681-689, 2018-The aim of this study was to verify the reliability and validity of using submaximal loads from the load-velocity relationship to predict the actual 1 repetition maximum (1RM) in the deadlift. Data from 11 resistance-trained athletes were analyzed performing three 1RM assessments separated by at least 3 days. Reliability was assessed by comparing predicted 1RMs of sessions 2 and 3, whereas for validity purposes, predicted 1RMs of session 3 were compared with actual 1RMs of session 2. Mean concentric velocity at 1RM (v at 1RM) was entered in individualized linear regression equations, derived from the load-velocity relationship for 3 (20-60%, 40-80%, and 60-90% of 1RM), 4 (20-80% and 40-90% of 1RM), and 5 (20-90% of 1RM) incremental loads to predict 1RMs. There were trivial changes for all predicted 1RMs between sessions with 20-90% of 1RM being the most reliable model. Similarly, the actual 1RM was very stable (effect size [ES] = 0.04, 90% confidence limit [CL] [-0.03 to 0.12], typical error of measurement [TE] = 3.4 kg [2.5-5.4], intraclass coefficient [ICC] = 0.99 [0.96-0.996], and coefficient of variation [CV] = 1.9% [1.4-3.0]), whereas the v at 1RM was unreliable between trials (ES = -0.30, 90% CL [-0.78 to 0.17], TE = 0.029 m·s [0.022-0.047], ICC = 0.63 [0.19-0.86], and CV = 15.7% [11.7-26.1]). However, predicted 1RMs computed from all submaximal load ranges substantially overestimated the actual 1RM with considerable differences between athletes. Although 1RM predictions showed high reliability, they all overestimated the actual 1RM, which was stable between sessions. Therefore, it is not recommended to apply the prediction models used in this study to compute daily 1RMs.
MeSH term(s)	Humans ; Male ; Muscle Strength/physiology ; Reproducibility of Results ; Weight Lifting/physiology ; Young Adult
Language	English
Publishing date	2018-03
Publishing country	United States
Document type	Journal Article
ZDB-ID	1156349-7
ISSN	1533-4287 ; 1064-8011
ISSN (online)	1533-4287
ISSN	1064-8011
DOI	10.1519/JSC.0000000000002369
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Zs.A 6263: Show issues

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Article: "I Am Half of a Person": Lived Experiences of Individuals Living With Ostomy After Surgery in Rural Haiti.

Chery, Maurice J / Henderson, Rebecca / Dubique, Kobel / Camilus, Adler / Eliacin, Henry Claude / Pinard, Jacquemine / Toussaint, Eric / Clisbee, Mary

Qualitative health research

2024 , Page(s) 10497323241229420

Abstract: Intestinal ostomy can have significant effects on lives and lived experiences. However, limited research exists on the experiences of persons with ostomy in low-resource settings, such as rural Haiti. This study aimed to explore the lived experiences of ... ...

Abstract	Intestinal ostomy can have significant effects on lives and lived experiences. However, limited research exists on the experiences of persons with ostomy in low-resource settings, such as rural Haiti. This study aimed to explore the lived experiences of Haitians with an ostomy, focusing on the physical, psychological, and social aspects of their post-operative lives. We conducted 9 semi-structured, in-depth interviews with participants who had undergone ostomy surgery at the Hôpital Universitaire de Mirebalais in Haiti. Employing interpretative phenomenological analysis (IPA), we iteratively examined transcripts to identify convergent and divergent codes, which were then grouped into themes to better understand the participants' experiences. Three themes emerged: (a) ostomy as a social disease, which has severe impacts on relationships and place in society; (b) ostomy as altering self-image, leading participants to reflect on their identity and the underlying causes of their condition and to reevaluate their necessities and abilities; and (c) ostomy as an arduous medical journey, characterized by pain, distress, uncertainty, and disillusionment, but also resiliency, improvisation, and hope. This study highlights the multifaceted experiences of persons with ostomy in the low-resource rural environment of Haiti and underscores the need for improved access to medical care, financial support, and psychosocial and caregiving resources for these individuals. Findings also emphasize the importance of medical providers' improved understanding in making medical decisions, and cultural and socioeconomic factors in developing effective support strategies.
Language	English
Publishing date	2024-02-08
Publishing country	United States
Document type	Journal Article
ZDB-ID	1275716-0
ISSN	1552-7557 ; 1049-7323
ISSN (online)	1552-7557
ISSN	1049-7323
DOI	10.1177/10497323241229420
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Article: Understanding the impact of stress in teleostean reproduction

Raju, Murugananthkumar / Sudhakumari, Cheni-Chery

Shanghai Ocean University. Aquaculture and fisheries. 2022 May 05,

2022

Abstract: Fishes exert stress response in a variety of ways depending on the type of the stressor. The stress responses are activated through a cascade mechanism stimulated by the stressor which involve hypothalamus–hypophyseal–interrenal (HHI) axis, ... ...

Abstract	Fishes exert stress response in a variety of ways depending on the type of the stressor. The stress responses are activated through a cascade mechanism stimulated by the stressor which involve hypothalamus–hypophyseal–interrenal (HHI) axis, catecholamines, and gonadotropins. Adaptive stress responses may have positive impact on the fish survival and reproduction while continuous or prolonged stress cause negative effects on the fish reproduction. Corticotropin releasing factor and adrenocorticotropic hormone are the principal hormones responsible to produce corticosteroids through the HHI axis. Cortisol acts differentially on the stress response as it helps at the early developmental stage conversely it impairs the gonadal function. Catecholamines have a critical role in the maintenance of body homeostasis and intermediary metabolism also it has predominant role in the reproductive function. Besides hormones, few genetic and epigenetic factors have been identified to understand the molecular responses to stress however, genome wide associated studies will be initiated to investigate complete picture of the stress mechanism. Further, recent evidence suggests that there is a growing concern in determining the correlation between the stress hormone level and its associated gene function. Hence, this review highlights the stress responses and its regulation in different axis, genetic and epigenetic factors related to stress, and the integration of recent technologies and novel hypotheses to unravel the mechanism of stress response in fish reproduction.
Keywords	aquaculture ; catecholamines ; corticotropin ; cortisol ; epigenetics ; fish ; genes ; gonadotropins ; gonads ; homeostasis ; metabolism ; reproduction ; stress response
Language	English
Dates of publication	2022-0505
Publishing place	Elsevier B.V.
Document type	Article
Note	Pre-press version
ISSN	2468-550X
DOI	10.1016/j.aaf.2022.05.001
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Article ; Online: A meta-analysis on the effect of proximal landing zone location on stroke and mortality in thoracic endovascular aortic repair.

Ma, Yuchi / Siddiqui, Mishal S / Farhan, Syed A / Albuquerque, Francisco C / Larson, Robert A / Levy, Mark M / Chery, Josue / Newton, Daniel H

Journal of vascular surgery

2023 Volume 78, Issue 6, Page(s) 1559–1566.e5

Abstract: Background: Thoracic endovascular aortic repair (TEVAR) involving the aortic arch may increase the opportunity for stroke owing to disruption of cerebral circulation and embolization. In this study, a systematic meta-analysis was performed to examine ... ...

Abstract	Background: Thoracic endovascular aortic repair (TEVAR) involving the aortic arch may increase the opportunity for stroke owing to disruption of cerebral circulation and embolization. In this study, a systematic meta-analysis was performed to examine the impact of proximal landing zone location on stroke and 30-day mortality after TEVAR. Methods: MEDLINE and Cochrane Library were searched for all original studies of TEVAR reporting outcomes of stroke or 30-day mortality for at least two adjacent proximal landing zones, based on the Ishimaru classification scheme. Forest plots were created using relative risks (RR) with 95% confidence intervals (CI). An I Results: Of the 57 studies examined, a total of 22,244 patients (male 73.1%, aged 71.9 ± 11.5 years) were included in the meta-analysis, with 1693 undergoing TEVAR with proximal landing zone 0, 1931 with zone 1, 5839 with zone 2, and 3089 with zone 3 and beyond. The overall risk of clinically evident stroke was 2.7% for zones ≥3, 6.6% for zone 2, 7.7% for zone 1, and 14.2% for zone 0. More proximal landing zones were associated with higher risks of stroke compared with distal (zone 2 vs ≥3: RR, 2.14; 95% CI, 1.43-3.20; P = .0002; I Conclusions: The risk of stroke from TEVAR is lowest in zone 3 and beyond, increasing significantly as the landing zone is moved proximally. Furthermore, perioperative mortality is increased with zone 0 compared with zone 1. Therefore, risk of stent grafting in the proximal arch should be weighed against alternative surgical or nonoperative options. It is anticipated that the risk of stroke will improve with further development of stent graft technology and implantation technique.
MeSH term(s)	Humans ; Male ; Endovascular Aneurysm Repair ; Cerebrovascular Circulation ; Embolization, Therapeutic ; Stroke/etiology
Language	English
Publishing date	2023-05-17
Publishing country	United States
Document type	Meta-Analysis ; Journal Article ; Review
ZDB-ID	605700-7
ISSN	1097-6809 ; 0741-5214
ISSN (online)	1097-6809
ISSN	0741-5214
DOI	10.1016/j.jvs.2023.05.014
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