LIVIVO - Search results -

Search results

Result 1 - 10 of total 150

Search options

Article ; Online: Nanoencapsulation of general anaesthetics.

Abdoullateef, Basma M T / El-Din Al-Mofty, Saif / Azzazy, Hassan M E

Nanoscale advances

2024 Volume 6, Issue 5, Page(s) 1361–1373

Abstract: General anaesthetics are routinely used to sedate patients during prolonged surgeries and ... ...

Abstract	General anaesthetics are routinely used to sedate patients during prolonged surgeries and administered
Language	English
Publishing date	2024-02-15
Publishing country	England
Document type	Journal Article ; Review
ISSN	2516-0230
ISSN (online)	2516-0230
DOI	10.1039/d3na01012k
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: ROLE OF DIMETHYL FUMARATE (NRF2 ACTIVATOR) IN REDUCING OF CIPROFLOXACIN-INDUCED HEPATOTOXICITY IN RATS VIA THE NRF2/HO-1 PATHWAY.

Jawad, Mahmood / Al-Akkam, Karam / Mohammed, Manar / Hassan, Saif M

Wiadomosci lekarskie (Warsaw, Poland : 1960)

2023 Volume 76, Issue 5 pt 1, Page(s) 1001–1006

Abstract: Objective: The aim: The present study aims to study the effect of DMF on ciprofloxacin-induced liver damage as assessed by liver function and liver pathology and to study this effect if it is thought to activate the Nrf2 antioxidant defense mechanism.!## ...

Abstract	Objective: The aim: The present study aims to study the effect of DMF on ciprofloxacin-induced liver damage as assessed by liver function and liver pathology and to study this effect if it is thought to activate the Nrf2 antioxidant defense mechanism. Patients and methods: Materials and methods: G1 (control), G2 (ciprofloxacin group), G3 and G4 (two DMF groups rats treated with DMF 50mg and 100mg), and G5 and G6 (two DMF groups rats treated with DMF 50mg and 100mg) (two ciprofloxacin Plus DMF at 50 mg and 100 mg). The tests included study of liver function, Nrf2 analysis, and anti-oxidant enzyme analysis. Results: Results: The serum blood Nrf2, HO-1, and tissue anti-oxidant enzymes all increased after ciprofloxacin treatment. The serum levels of Nrf2 and HO-1 were higher in the ciprofloxacin plus DMF groups, but anti-oxidant enzymes were lower. DMF increased Nrf2 expression in rats when ciprofloxacin caused hepatotoxicity. Conclusion: Conclusions: DMF lowers experimental hepatotoxicity in vivo. This effect is thought to activate the Nrf2 antioxidant defense mechanism.
MeSH term(s)	Humans ; Dimethyl Fumarate/pharmacology ; Antioxidants/pharmacology ; NF-E2-Related Factor 2/metabolism ; NF-E2-Related Factor 2/pharmacology ; Oxidative Stress ; Chemical and Drug Induced Liver Injury/drug therapy
Chemical Substances	Dimethyl Fumarate (FO2303MNI2) ; Antioxidants ; NF-E2-Related Factor 2
Language	English
Publishing date	2023-06-16
Publishing country	Poland
Document type	Journal Article
ZDB-ID	414731-5
ISSN	0043-5147 ; 1895-0485 ; 0860-8865
ISSN	0043-5147 ; 1895-0485 ; 0860-8865
DOI	10.36740/WLek202305117
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 646: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: USE OF INFLIXIMAB TO ATTENUATE CEREBRAL APOPTOSIS INDUCED BY CEREBRAL ISCHEMIA/REPERFUSION IN MALE RATS.

Hassan, Saif M / Mohammed, Manar Hameed / Jawad, Mahmood J / Abbas, Ashwaq Najemaldeen

Wiadomosci lekarskie (Warsaw, Poland : 1960)

2023 Volume 76, Issue 2, Page(s) 326–331

Abstract: Objective: The aim: The purpose of the research was to study the role of infiximab global cerebral ischemia-reperfusion injury.: Patients and methods: Materials and methods: The rats were split into five groups: Sham group; Control group: occlusion ... ...

Abstract	Objective: The aim: The purpose of the research was to study the role of infiximab global cerebral ischemia-reperfusion injury. Patients and methods: Materials and methods: The rats were split into five groups: Sham group; Control group: occlusion of the common carotid artery for 60 minutes, and sub-sequently reperfusion for an hour without receiving any medication; Vehicle group: as the control group, but 72 hours before to the ischemia, they were given the medication 0.9 NaCl intraperitoneally (i.p); Treated group-1: as the control group, plus 3 mg/kg of IFX intraperitoneally (i.p) 72 hours prior to ischemia; Treated group-2: as the control group, plus 7 mg/kg of IFX intraperitoneally (i.p) 72 hours prior to ischemia. Results: Results: Pre-treatment with IFX significantly reduced the percentage of infarct area, but in the IFX (7 mg/kg) group, the infarct area was smaller than at the low dose. The ischemia group had a significant elevated of TNF- α and caspase-3 while a significant lowered in CAT and SOD levels. The pre-treatment with IFX, the TNF- α and caspase-3 levels lowered significantly, furthermore, significantly increased CAT and SOD levels activity (P≤0.05) as compared with IR group. Among effective groups, I/R+IFX (7mg/kg) group more effective in lowering TNF- α and caspase than I/R+IFX (3mg/kg) group. Conclusion: Conclusions: Infiximab has neuroprotective effective due to its powerful TNF- α blocker and limit ROS release and cell death signaling which protects the neurons from injury during cerebral ischemia reperfusion.
MeSH term(s)	Humans ; Infliximab/pharmacology ; Infliximab/therapeutic use ; Caspase 3/pharmacology ; Caspase 3/therapeutic use ; Cerebral Infarction/drug therapy ; Cerebral Infarction/etiology ; Brain Ischemia/drug therapy ; Apoptosis ; Tumor Necrosis Factor-alpha ; Reperfusion ; Superoxide Dismutase
Chemical Substances	Infliximab (B72HH48FLU) ; Caspase 3 (EC 3.4.22.-) ; Tumor Necrosis Factor-alpha ; Superoxide Dismutase (EC 1.15.1.1)
Language	English
Publishing date	2023-04-03
Publishing country	Poland
Document type	Journal Article
ZDB-ID	414731-5
ISSN	0043-5147 ; 1895-0485 ; 0860-8865
ISSN	0043-5147 ; 1895-0485 ; 0860-8865
DOI	10.36740/WLek202302112
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 646: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Intercalation of C60 into MXene Multilayers: A Promising Approach for Enhancing the Electrochemical Properties of Electrode Materials for High-Performance Energy Storage Applications.

Bukhari, Hassan / Iqbal, Asad M / Awan, Saif Ullah / Hussain, Danish / Shah, Saqlain A / Rizwan, Syed

ACS omega

2023 Volume 9, Issue 1, Page(s) 227–238

Abstract: In this study, we report on the enhancement of the electrochemical properties of MXene by intercalating C60 nanoparticles between its layers. The aim was to increase the interlayer spacing of MXene, which has a direct effect on capacitance by allowing ... ...

Abstract	In this study, we report on the enhancement of the electrochemical properties of MXene by intercalating C60 nanoparticles between its layers. The aim was to increase the interlayer spacing of MXene, which has a direct effect on capacitance by allowing the electrolyte flow in the electrode. To achieve this, various concentrations of Ti
Language	English
Publishing date	2023-12-28
Publishing country	United States
Document type	Journal Article
ISSN	2470-1343
ISSN (online)	2470-1343
DOI	10.1021/acsomega.3c04058
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: ROLE OF PRE-CESAREAN SECTION CEFOTAXIME IN AMELIORATED POST-CESAREAN COMPLICATION.

Jawad, Mahmood J / Hassan, Saif M / Obaid, Ahmed Kareem / Hadi, Najah R

Wiadomosci lekarskie (Warsaw, Poland : 1960)

2022 Volume 75, Issue 4 pt 1, Page(s) 818–823

Abstract: Objective: The aim: The purpose of this study was to examine the efficacy of cefotaxime before and after skin incision in avoiding post-operative infection complications in caesarean section women, also evaluation the efficacy of cefotaxime in reducing ... ...

Abstract	Objective: The aim: The purpose of this study was to examine the efficacy of cefotaxime before and after skin incision in avoiding post-operative infection complications in caesarean section women, also evaluation the efficacy of cefotaxime in reducing post-caesarean section complications. Patients and methods: Materials and methods: We conducted 150 women who undergoing caesarean section in the Obstetrics & Gynecological Department, Babylon government from January, 2021 to March, 2021. The caesarean operations were done by using standard protocols. Each patient was examined daily and post-operative infectious. Women were randomly divided into three groups; each group contains 50 women; Group 1: (control) given normal saline 12 hr. before and after skin incision. Group 2 (pre-operation antibiotic): given single dose of cefotaxime 1 g intravenously 12 hr. before skin incision, and Group 3 (post-operation antibiotic): given single dose of cefotaxime 1 g intravenously 12 hr after operation. Results: Results: The outcome measures were post-operative febrile morbidity, healing period and urinary tract infections, in addition to socioeconomic state of each woman. Conclusion: Conclusions: cefotaxime pre-cesarean section could ameliorate post-operative problems such as infection of surgical wound, febrile, and urinary tract infections.
MeSH term(s)	Anti-Bacterial Agents/therapeutic use ; Cefotaxime/therapeutic use ; Cesarean Section/adverse effects ; Cesarean Section/methods ; Female ; Humans ; Postoperative Complications/drug therapy ; Postoperative Complications/etiology ; Postoperative Complications/prevention & control ; Pregnancy ; Surgical Wound Infection/drug therapy ; Surgical Wound Infection/etiology ; Surgical Wound Infection/prevention & control ; Urinary Tract Infections/drug therapy ; Urinary Tract Infections/etiology ; Urinary Tract Infections/prevention & control
Chemical Substances	Anti-Bacterial Agents ; Cefotaxime (N2GI8B1GK7)
Language	English
Publishing date	2022-03-11
Publishing country	Poland
Document type	Journal Article ; Randomized Controlled Trial
ZDB-ID	414731-5
ISSN	0043-5147 ; 1895-0485 ; 0860-8865
ISSN	0043-5147 ; 1895-0485 ; 0860-8865
DOI	10.36740/WLek202204113
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 646: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Intercalation of C60 into MXene Multilayers

Hassan Bukhari / Asad M. Iqbal / Saif Ullah Awan / Danish Hussain / Saqlain A. Shah / Syed Rizwan

ACS Omega, Vol 9, Iss 1, Pp 227-

A Promising Approach for Enhancing the Electrochemical Properties of Electrode Materials for High-Performance Energy Storage Applications

2023 Volume 238

Keywords	Chemistry ; QD1-999
Language	English
Publishing date	2023-12-01T00:00:00Z
Publisher	American Chemical Society
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Pattern of antibiotic use for acute respiratory infections among out-patients in South Asian Region: Protocol for a systematic review.

Al-Amin, Saif / Hassan, Md Zakiul / Saif-Ur-Rahman, K M / Chowdhury, Muhammad Abdul Baker / Morrison, Sharon D / Donevant, Sara B / Chowdhury, Fahmida

Medicine

2021 Volume 100, Issue 4, Page(s) e22398

Abstract: Background: South Asian region has been experiencing the increasing burden of antimicrobial resistance (AMR) primarily due to over and irrational prescribing of antibiotics. Acute respiratory infections (ARIs) are the leading cause of out-patients' ... ...

Abstract	Background: South Asian region has been experiencing the increasing burden of antimicrobial resistance (AMR) primarily due to over and irrational prescribing of antibiotics. Acute respiratory infections (ARIs) are the leading cause of out-patients' visits in the region. Despite commonly known viral aetiology, ARI is the single largest reason for antibiotic prescriptions contributing the exponential growth of AMR in the region. Collated data on antibiotic consumption for ARI at outpatients and resistance pattern of respiratory pathogen are lacking in the region. Methods: MEDLINE, Cochrane, CINAHL Plus (EBSCO), and Web of Science will be searched for eligible papers. Titles and abstracts, and full texts of the relevant studies will be screened by 2 independent reviewers against the inclusion criteria. Data extraction and quality of the studies will be assessed by 2 reviewers independently using the JBI Critical Appraisal Tools. A third reviewer will resolve any disagreement at any point between 2 reviewers. Results: The review will assess proportions of ARI patients receiving antibiotic therapy and types of antibiotics prescribed among outpatients of all ages in South Asia. This review will also assess the pattern of antimicrobial resistance among respiratory pathogens causing ARI in the region. Conclusions: This systematic review will evaluate published literature, summarize the existing data on the antibiotic prescribing patterns for outpatients with ARI in South Asia. The holistic finding of the proportion of patients receiving antibiotic therapy for ARI, proportion of different types of antibiotic received, and resistance against respiratory pathogen might guide future research. This underscores a need for formulating regional and national policy for AMR mitigation strategy, and revising clinical practice guidelines for the clinician to ensure rational use of antibiotics for ARI. Prospero: registration no: CRD42018116658.
MeSH term(s)	Acute Disease ; Anti-Bacterial Agents/therapeutic use ; Asia ; Humans ; Outpatients/statistics & numerical data ; Patient Acceptance of Health Care/statistics & numerical data ; Research Design ; Respiratory Tract Infections/drug therapy ; Systematic Reviews as Topic
Chemical Substances	Anti-Bacterial Agents
Language	English
Publishing date	2021-01-22
Publishing country	United States
Document type	Journal Article
ZDB-ID	80184-7
ISSN	1536-5964 ; 0025-7974
ISSN (online)	1536-5964
ISSN	0025-7974
DOI	10.1097/MD.0000000000022398
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ua VI Zs.171: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Identification of phytochemicals as putative ligands for the targeted modulation of peroxisome proliferator-activated receptor α (PPARα) in animals.

Hassan, Faiz-Ul / Rehman, M Saif-Ur / Javed, Maryam / Ahmad, Khalil / Fatima, Israr / Safdar, Muhammad / Ashraf, Noman / Nadeem, Asif

Journal of biomolecular structure & dynamics

2023 , Page(s) 1–12

Abstract: The PPAR family of transcription factors are ligand-activated and regulate diverse functions including metabolic, neurological, and inflammatory diseases, neurodegenerative disorders, fertility or reproduction in the body. Specifically, PPARα is known to ...

Abstract	The PPAR family of transcription factors are ligand-activated and regulate diverse functions including metabolic, neurological, and inflammatory diseases, neurodegenerative disorders, fertility or reproduction in the body. Specifically, PPARα is known to play a role in reducing the levels of circulating triglycerides and regulating energy homeostasis in livestock animals. This study aimed to identify phytochemicals that could serve as ligands for modulation of the bovine nuclear peroxisome proliferator-activated receptor alpha (PPARα) using molecular docking studies. Therefore, we investigated 1000 flavonoids belonging to different groups for their ability to bind to PPARα using molecular docking. Out of 1000, 6 top lead compounds with maximum binding affinity, evaluated through molecular docking, were further analysed for physicochemical properties and drug-likeness attributes. The results revealed that two flavonoids, Quercetin-3-o-rhamnoside and (-)- epicatechingallate, which are known fatty acid synthase inhibitors, demonstrated high docking scores with PPARα (-8.66 kcal/mol and -8.49 kcal/mol, respectively) and low RMSD values with PPARα (1.61 kcal/mol and 1.28 kcal/mol, respectively) as compared to PPARα agonist (
Language	English
Publishing date	2023-10-14
Publishing country	England
Document type	Journal Article
ZDB-ID	49157-3
ISSN	1538-0254 ; 0739-1102
ISSN (online)	1538-0254
ISSN	0739-1102
DOI	10.1080/07391102.2023.2268185
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 2093: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Multifunctional Hemostatic PVA/Chitosan Sponges Loaded with Hydroxyapatite and Ciprofloxacin.

Al-Mofty, Saif El-Din / Karaly, Ali H / Sarhan, Wessam Awad / Azzazy, Hassan M E

ACS omega

2022 Volume 7, Issue 15, Page(s) 13210–13220

Abstract: The present study describes the development of multifunctional hemostatic sponges to control bleeding. Chitosan (Ch) and poly(vinyl alcohol) (PVA) were selected as the basic polymeric matrix [Ch/PVA] for sponges. Glycerol and citric acid were used as ... ...

Abstract	The present study describes the development of multifunctional hemostatic sponges to control bleeding. Chitosan (Ch) and poly(vinyl alcohol) (PVA) were selected as the basic polymeric matrix [Ch/PVA] for sponges. Glycerol and citric acid were used as crosslinkers [Ch/PVA/G(Cl)] to enhance the mechanical properties of the developed sponges. Ciprofloxacin (AB) was added to the developed sponge to impart antibacterial activity. Hydroxyapatite (HA) was also added, which would make the sponge suitable for bone surgery. Among the developed sponges, the Ch/PVA/G(Cl)-HA-AB sponge demonstrated enhanced cell viability, mechanical properties, and strong antimicrobial effect against
Language	English
Publishing date	2022-04-11
Publishing country	United States
Document type	Journal Article
ISSN	2470-1343
ISSN (online)	2470-1343
DOI	10.1021/acsomega.2c00654
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: An Intelligent and Reliable Hyperparameter Optimization Machine Learning Model for Early Heart Disease Assessment Using Imperative Risk Attributes.

Ansarullah, Syed Immamul / Mohsin Saif, Syed / Abdul Basit Andrabi, Syed / Kumhar, Sajadul Hassan / Kirmani, Mudasir M / Kumar, Dr Pradeep

publication RETRACTED

Journal of healthcare engineering

2022 Volume 2022, Page(s) 9882288

Abstract: Heart disease is a severe disorder, which inflicts an adverse burden on all societies and leads to prolonged suffering and disability. We developed a risk evaluation model based on visible low-cost significant noninvasive attributes using hyperparameter ... ...

Abstract	Heart disease is a severe disorder, which inflicts an adverse burden on all societies and leads to prolonged suffering and disability. We developed a risk evaluation model based on visible low-cost significant noninvasive attributes using hyperparameter optimization of machine learning techniques. The multiple set of risk attributes is selected and ranked by the recursive feature elimination technique. The assigned rank and value to each attribute are validated and approved by the choice of medical domain experts. The enhancements of applying specific optimized techniques like decision tree, k-nearest neighbor, random forest, and support vector machine to the risk attributes are tested. Experimental results show that the optimized random forest risk model outperforms other models with the highest sensitivity, specificity, precision, accuracy, AUROC score, and minimum misclassification rate. We simulate the results with the prevailing research; they show that it can do better than the existing risk assessment models with exceptional predictive accuracy. The model is applicable in rural areas where people lack an adequate supply of primary healthcare services and encounter barriers to benefit from integrated elementary healthcare advances for initial prediction. Although this research develops a low-cost risk evaluation model, additional research is needed to understand newly identified discoveries about the disease.
MeSH term(s)	Cluster Analysis ; Heart Diseases ; Humans ; Machine Learning ; Risk Assessment ; Support Vector Machine
Language	English
Publishing date	2022-04-12
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Retracted Publication
ZDB-ID	2545054-2
ISSN	2040-2309 ; 2040-2295
ISSN (online)	2040-2309
ISSN	2040-2295
DOI	10.1155/2022/9882288
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

To top

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito