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Article ; Online: Erratum for Cheng et al., "Group A

Cheng, Yi-Lin / Kuo, Chih-Feng / Lu, Shiou-Ling / Omori, Hiroko / Wu, Ya-Na / Hsieh, Cheng-Lu / Noda, Takeshi / Wu, Shang-Rung / Anderson, Robert / Lin, Chiou-Feng / Chen, Chia-Ling / Wu, Jiunn-Jong / Lin, Yee-Shin

mBio

2021 Volume 12, Issue 4, Page(s) e0225021

Language	English
Publishing date	2021-08-31
Publishing country	United States
Document type	Journal Article ; Published Erratum
ZDB-ID	2557172-2
ISSN	2150-7511 ; 2161-2129
ISSN (online)	2150-7511
ISSN	2161-2129
DOI	10.1128/mBio.02250-21
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Dr Cheng and Colleagues Reply.

Cheng, Chih-Ming / Chen, Mu-Hong / Yang, Cheng-Hung / Tsai, Shih-Jen / Tsai, Chia-Fen

The Journal of clinical psychiatry

2020 Volume 81, Issue 3

MeSH term(s)	Cohort Studies ; Dementia ; Follow-Up Studies ; Humans ; Research Design ; Taiwan
Language	English
Publishing date	2020-03-24
Publishing country	United States
Document type	Letter ; Research Support, Non-U.S. Gov't ; Comment
ZDB-ID	716287-x
ISSN	1555-2101 ; 0160-6689
ISSN (online)	1555-2101
ISSN	0160-6689
DOI	10.4088/JCP.19lr13217a
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Zs.B 108: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
Zs.MO 247: Show issues

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Book: Tributes to Yuan-Cheng Fung on his 90th birthday

Fung, Yuan-cheng / Shu, Jian

biomechanics ; from molecules to man

2010

Author's details	ed. Shu Chien
Language	English
Size	IX, 350 S. : Ill., graph. Darst.
Publisher	World Scientific
Publishing place	Hackensack, NJ u.a.
Publishing country	United States
Document type	Book
HBZ-ID	HT016181812
ISBN	981-4289-87-6 ; 978-981-4289-87-0
Database	Catalogue ZB MED Medicine, Health

In stock of ZB MED Cologne/Königswinter

Shelf mark	Loan status	Location
2010 A 1263	order for loan	Magazin

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Article ; Online: Enhancing β-cell function and identity in type 2 diabetes: The protective role of Coptis deltoidea C. Y. Cheng et Hsiao via glucose metabolism modulation and AMPK signaling activation.

Zhang, Shan / Zhang, Yueying / Wen, Zhige / Chen, Yupeng / Bu, Tianjie / Yang, Yanan / Ni, Qing

Phytomedicine : international journal of phytotherapy and phytopharmacology

2024 Volume 128, Page(s) 155396

Abstract: ... and identity impairment resulting from high glucose exposure. In China, Coptis deltoidea C. Y. Cheng ...

Abstract	Background: Abnormalities in glucose metabolism may be the underlying cause of β-cell dysfunction and identity impairment resulting from high glucose exposure. In China, Coptis deltoidea C. Y. Cheng et Hsiao (YL) has demonstrated remarkable hypoglycemic effects. Hypothesis/purpose: To investigate the hypoglycemic effect of YL and determine the mechanism of YL in treating diabetes. Methods: A type 2 diabetes mouse model was used to investigate the pharmacodynamics of YL. YL was administrated once daily for 8 weeks. The hypoglycemic effect of YL was assessed by fasting blood glucose, an oral glucose tolerance test, insulin levels, and other indexes. The underlying mechanism of YL was examined by targeting glucose metabolomics, western blotting, and qRT-PCR. Subsequently, the binding capacity between predicted AMP-activated protein kinase (AMPK) and important components of YL (Cop, Ber, and Epi) were validated by molecular docking and surface plasmon resonance. Then, in AMPK knockdown MIN6 cells, the mechanisms of Cop, Ber, and Epi were inversely confirmed through evaluations encompassing glucose-stimulated insulin secretion, markers indicative of β-cell identity, and the examination of glycolytic genes and products. Results: YL (0.9 g/kg) treatment exerted notable hypoglycemic effects and protected the structural integrity and identity of pancreatic β-cells. Metabolomic analysis revealed that YL inhibited the hyperactivated glycolysis pathway in diabetic mice, thereby regulating the products of the tricarboxylic acid cycle. KEGG enrichment revealed the intimate relationship of this process with the AMPK signaling pathway. Cop, Ber, and Epi in YL displayed high binding affinities for AMPK protein. These compounds played a pivotal role in preserving the identity of pancreatic β-cells and amplifying insulin secretion. The mechanism underlying this process involved inhibition of glucose uptake, lowering intracellular lactate levels, and elevating acetyl coenzyme A and ATP levels through AMPK signaling. The use of a glycolytic inhibitor corroborated that attenuation of glycolysis restored β-cell identity and function. Conclusion: YL demonstrates significant hypoglycemic efficacy. We elucidated the potential mechanisms underlying the protective effects of YL and its active constituents on β-cell function and identity by observing glucose metabolism processes in pancreatic tissue and cells. In this intricate process, AMPK plays a pivotal regulatory role.
Language	English
Publishing date	2024-01-28
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1205240-1
ISSN	1618-095X ; 0944-7113
ISSN (online)	1618-095X
ISSN	0944-7113
DOI	10.1016/j.phymed.2024.155396
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Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

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Article: Improvement of inflammatory response and gastrointestinal function in perioperative of cholelithiasis by Modified Xiao-Cheng-Qi decoction.

Sun, Bao-Fang / Zhang, Fan / Chen, Qiang-Pu / Wei, Qiang / Zhu, Wen-Tao / Ji, Hai-Bin / Zhang, Xing-Yuan

World journal of clinical cases

2022 Volume 11, Issue 4, Page(s) 830–843

Abstract: ... the effects of Modified Xiao-Cheng-Qi decoction (MXD) on inflammatory response and GI function ...

Abstract	Background: In the perioperative period of biliary surgery, various factors can induce the release of a large number of inflammatory factors, leading to an imbalance in pro-inflammatory and anti-inflammatory responses and resulting in gastrointestinal (GI) dysfunction. Enhanced Recovery After Surgery protocols in biliary surgery have been shown to reduce the stress response and accelerate postoperative recovery. It is crucial to reduce the inflammatory response and promote the recovery of GI function after biliary surgery, both of which are the basis and key for perioperative care and postoperative recovery. Aim: To better understand the effects of Modified Xiao-Cheng-Qi decoction (MXD) on inflammatory response and GI function in the perioperative management of cholelithiasis and their correlation. Methods: This was a prospective randomized placebo-controlled trial, in which 162 patients who received biliary tract surgery were randomly assigned to three groups: MXD group, XD group, and placebo-control group. The observed parameters included frequency of bowel sounds, time of first flatus and defecation, time of diet, and amount of activity after surgery. The serum levels of C-reactive protein (CRP), interleukin (IL)-6, IL-10, serum amyloid A protein (SAA), and substance P were measured by the enzyme-linked immunosorbent assay. Then, the spearman correlation coefficient was used to analyze the relationship between the indicators of GI function and inflammation. Results: Compared to the placebo-control, improvements in GI function were observed in the MXD groups including reduced incidence of nausea, vomiting, and bloating; and earlier first exhaust time, first defecation time, and feeding time after surgery ( Conclusion: Treatment with MXD can relieve inflammatory response and improve GI function after surgery. Moreover, there are significant correlations between them. Furthermore, it does not cause serious adverse reactions.
Language	English
Publishing date	2022-12-04
Publishing country	United States
Document type	Clinical Trial
ISSN	2307-8960
ISSN	2307-8960
DOI	10.12998/wjcc.v11.i4.830
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Article ; Online: Change of the spatial and temporal pattern of ecological vulnerability: A case study on Cheng-Yu urban agglomeration, Southwest China

Jiang, Bohan / Chen, Wei / Dai, Xiaoai / Xu, Min / Liu, Lanfa / Sakai, Tetsuro / Li, Siliang

Ecological Indicators. 2023 May, v. 149 p.110161-

2023

Abstract: China's urban economy has developed rapidly over the decades, and the Cheng-Yu urban agglomeration ... of Cheng-Yu urban agglomeration is mainly mild and moderate, with an overall high distribution in Chongqing ...

Abstract	China's urban economy has developed rapidly over the decades, and the Cheng-Yu urban agglomeration has become one of China's four typical urban agglomerations, with a large population and a high level of economic development. However, the conflict between humans and the environment is becoming increasingly prominent together with economic development. In order to protect the ecological environment in urban areas, thus scientific understanding and assessment of ecological vulnerability are beneficial to establishing regional conservation measures, and serve as a key means to maintain environmental health. Based on the "Sensitivity-Resilience-Pressure" (SRP) model, this study considered remote sensing, geographic and statistical data to construct an evaluation system for regional ecological vulnerability. In addition, the coupled AHP (Analytic hierarchy process)-Entropy weighting model was proposed to obtain the weight of each evaluation indicator and analyze the spatio-temporal distribution characteristics of the ecological vulnerability of the study area during 2000-2020. The changes and the divergence pattern were depicted by the transfer matrix, dynamic degree and spatial auto-correlation. The results indicated that the ecological vulnerability of Cheng-Yu urban agglomeration is mainly mild and moderate, with an overall high distribution in Chongqing and Chengdu, while low in the central and north zone (e.g., Ziyang, Mianyang). It is consistent with the distribution of HH (High-High) and L-L (Low-Low) clusters, respectively, having a significant positive spatial correlation. In particular, the severely vulnerable area increased from 7059 km² in 2000 to 23553 km² in 2020, with an increased rate of 233.66 %. Combining the transfer matrix and dynamic degree, it was found that the ecological environment underwent a rapid deterioration followed by a slow recovery. This study provides a scientific reference for the ecological policy making which serves sustainable urban development.
Keywords	autocorrelation ; case studies ; environmental health ; issues and policy ; models ; urban development ; China ; Ecological vulnerability ; SRP model ; AHP-Entropy weighting model ; Cheng-Yu urban agglomeration
Language	English
Dates of publication	2023-05
Publishing place	Elsevier Ltd
Document type	Article ; Online
Note	Use and reproduction
ZDB-ID	2036774-0
ISSN	1872-7034 ; 1470-160X
ISSN (online)	1872-7034
ISSN	1470-160X
DOI	10.1016/j.ecolind.2023.110161
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Two new triterpenes isolated from Maytenus guangxiensis C. Y. Cheng et W. L. Sha and their antiproliferative activities

Huang, YuanYuan / Chen, Lu / Yao, Jing / Jia, XueGong / Deng, FuSheng / Mo, JingYa / Yuan, JingQuan

Natural Product Research. 2023 May 3, v. 37, no. 9 p.1498-1504

2023

Abstract: ... leaves of Maytenus guangxiensis C. Y. Cheng et W. L. Sha. Their structures were elucidated using 1D and ...

Abstract	Two new triterpenes, 3β, 7β-dihydroxyolean-12-en-11-one (1) and 3β-O-acetyl-7β-hydroxyolean-12-en-11-one (2), along with four known triterpenes 3β-hydroxyolean-12-en-11-one (3), β-amyrin (4), lup-20(29)-ene-1β, 3β-diol (5) and 1β, 3β-dihydroxy-urs-9(11)-12-diene (6), were isolated from the stems and leaves of Maytenus guangxiensis C. Y. Cheng et W. L. Sha. Their structures were elucidated using 1D and 2D NMR spectroscopy as well as MS and IR experiments. Compounds (3-6) were isolated from M. guangxiensis for the first time. Compounds 1–6 were evaluated for their antiproliferative activities against Eca-109, PANC-1, EJ and HeLa cell lines. The results showed that compounds 1–6 displayed a certain degree of inhibitory effects against the proliferation of various human cancer cell lines.
Keywords	Maytenus ; human cell lines ; humans ; neoplasm cells ; nuclear magnetic resonance spectroscopy ; research ; triterpenoids ; Maytenus guangxiensis ; triterpenes ; antiproliferative activities ; cancer cells
Language	English
Dates of publication	2023-0503
Size	p. 1498-1504.
Publishing place	Taylor & Francis
Document type	Article ; Online
ZDB-ID	2185747-7
ISSN	1478-6427 ; 1478-6419
ISSN (online)	1478-6427
ISSN	1478-6419
DOI	10.1080/14786419.2021.2023870
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Erratum: Cheng, Y.-C., et al. Evidence Supports PA Prescription for Parkinson's Disease: Motor Symptoms and Non-Motor Features: A Scoping Review. Int. J. Environ. Res. Public Health 2020

Cheng, Yi-Chen / Su, Chun-Hsien

International journal of environmental research and public health

2020 Volume 17, Issue 14

Abstract: The authors wish to make the following corrections to their paper published in IJERPH [1]: authors' affiliation [ ... ]. ...

Abstract	The authors wish to make the following corrections to their paper published in IJERPH [1]: authors' affiliation [...].
Language	English
Publishing date	2020-07-13
Publishing country	Switzerland
Document type	Published Erratum
ISSN	1660-4601
ISSN (online)	1660-4601
DOI	10.3390/ijerph17145024
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Metabolic Insight Into the Neuroprotective Effect of Tao-He-Cheng-Qi (THCQ) Decoction on ICH Rats Using Untargeted Metabolomics.

Yang, Rui-Pei / Cai, Da-Ke / Chen, Yu-Xing / Gang, Hai-Ning / Wei, Mei / Zhu, De-Quan / Li, Su-Mei / Yang, Jiu-Mei / Luo, Si-Ni / Bi, Xiao-Li / Sun, Dong-Mei

Frontiers in pharmacology

2021 Volume 12, Page(s) 636457

Abstract: Tao-He-Cheng-Qi decoction (THCQ) is an effective traditional Chinese medicine used to treat ...

Abstract	Tao-He-Cheng-Qi decoction (THCQ) is an effective traditional Chinese medicine used to treat intracerebral hemorrhage (ICH). This study was performed to investigate the possible neuroprotective effect of THCQ decoction on secondary brain damage in rats with intracerebral hemorrhage and to elucidate the potential mechanism based on a metabolomics approach. Sprague-Dawley (SD) rats were randomly divided into five groups: the sham group, collagenase-induced ICH model group, THCQ low-dose (THCQ-L)-treated group, THCQ moderate-dose (THCQ-M)-treated group and THCQ high-dose (THCQ-H)-treated group. Following 3 days of treatment, behavioral changes and histopathological lesions in the brain were estimated. Untargeted metabolomics analysis with multivariate statistics was performed by using ultrahigh-performance liquid chromatography-mass spectrometry (UPLC-Q-Exactive Orbitrap MS). THCQ treatment at two dosages (5.64 and 11.27 g/kg·d) remarkably improved behavior (
Language	English
Publishing date	2021-05-03
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2587355-6
ISSN	1663-9812
ISSN	1663-9812
DOI	10.3389/fphar.2021.636457
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Article ; Online: Response of the microbial community to phosphate-solubilizing bacterial inoculants on Ulmus chenmoui Cheng in Eastern China.

Song, Juan / Min, LiJing / Wu, JunRong / He, Qingfang / Chen, FengMao / Wang, Yang

PloS one

2021 Volume 16, Issue 2, Page(s) e0247309

Abstract: Phosphate-solubilizing bacteria (PSB) have beneficial effects on plant health and soil composition. To date, studies of PSB in soil have largely been performed under field or greenhouse conditions. However, less is known about the impact of introducing ... ...

Abstract	Phosphate-solubilizing bacteria (PSB) have beneficial effects on plant health and soil composition. To date, studies of PSB in soil have largely been performed under field or greenhouse conditions. However, less is known about the impact of introducing indigenous PSB in the field, including their effects on the local microbial community. In this study, we conducted greenhouse and field experiments to explore the effects of the addition of indigenous PSB on the growth of Chenmou elm (Ulmus chenmoui) and on the diversity and composition of the bacterial community in the soil. We obtained four bacterial isolates with the highest phosphate-solubilizing activity: UC_1 (Pseudomonas sp.), UC_M (Klebsiella sp.), UC_J (Burkholderia sp.), and UC_3 (Chryseobacterium sp.). Sequencing on the Illumina MiSeq platform showed that the inoculated PSB did not become the dominant strains in the U. chenmoui rhizosphere. However, the soil bacterial community structure was altered by the addition of these PSB. The relative abundance of Chloroflexi decreased significantly in response to PSB application in all treatment groups, whereas the populations of several bacteria, including Proteobacteria and Bacteroidetes, increased. Network analysis indicated that Chloroflexi was the most strongly negatively correlated with Proteobacteria, whereas Proteobacteria was strongly positively correlated with Bacteroidetes. Our findings indicate that inoculation with PSB (UC_1, UC_M, UC_J, and UC_3) can improve the growth of U. chenmoui and regulate its rhizosphere microbial community. Therefore, inoculation with these bacterial strains could promote the efficient cultivation and production of high-quality plant materials.
MeSH term(s)	Agricultural Inoculants/metabolism ; Burkholderia/metabolism ; China ; Microbiota/physiology ; Phosphates/metabolism ; Plants/microbiology ; Proteobacteria/metabolism ; Rhizosphere ; Soil/chemistry ; Soil Microbiology ; Ulmus/metabolism
Chemical Substances	Phosphates ; Soil
Language	English
Publishing date	2021-02-25
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0247309
Database	MEDical Literature Analysis and Retrieval System OnLINE

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