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  1. Article ; Online: Mitigating the Impact of COVID-19 on Adolescent and Young Adult Sexual Health Care.

    Zucker, Jason / Nagendra, Gowri / Burstein, Gale / Neu, Natalie

    Pediatrics

    2023  Volume 151, Issue Suppl 1

    MeSH term(s) Humans ; Adolescent ; Young Adult ; COVID-19 ; Sexual Health ; Sexual Behavior ; Sexual Partners
    Language English
    Publishing date 2023-04-03
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 207677-9
    ISSN 1098-4275 ; 0031-4005
    ISSN (online) 1098-4275
    ISSN 0031-4005
    DOI 10.1542/peds.2022-057267E
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The Potential Impact and Availability of Sexual Health Services During the COVID-19 Pandemic.

    Nagendra, Gowri / Carnevale, Caroline / Neu, Natalie / Cohall, Alwyn / Zucker, Jason

    Sexually transmitted diseases

    2020  Volume 47, Issue 7, Page(s) 434–436

    Abstract: As the COVID-19 pandemic causes upheaval in New York City (NYC), 1 consequence is the accessibility of sexual health services. The NYC STD Prevention Training Center at Columbia University administered an online provider survey to understand how the ... ...

    Abstract As the COVID-19 pandemic causes upheaval in New York City (NYC), 1 consequence is the accessibility of sexual health services. The NYC STD Prevention Training Center at Columbia University administered an online provider survey to understand how the COVID-19 pandemic is affecting the availability of sexual health care services regionally.
    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/epidemiology ; Coronavirus Infections/virology ; Health Services Accessibility/organization & administration ; Humans ; New York City/epidemiology ; Pandemics ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/virology ; Reproductive Health Services/supply & distribution ; SARS-CoV-2 ; Sexual Health
    Keywords covid19
    Language English
    Publishing date 2020-06-08
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 435191-5
    ISSN 1537-4521 ; 0148-5717
    ISSN (online) 1537-4521
    ISSN 0148-5717
    DOI 10.1097/OLQ.0000000000001198
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The Potential Impact & Availability of Sexual Health Services During the COVID-19 Pandemic

    Nagendra, Gowri / Carnevale, Caroline / Neu, Natalie / Cohall, Alwyn / Zucker, Jason

    Sexually Transmitted Diseases

    2020  Volume Publish Ahead of Print

    Keywords Public Health, Environmental and Occupational Health ; Microbiology (medical) ; Infectious Diseases ; Dermatology ; covid19
    Language English
    Publisher Ovid Technologies (Wolters Kluwer Health)
    Publishing country us
    Document type Article ; Online
    ZDB-ID 435191-5
    ISSN 1537-4521 ; 0148-5717
    ISSN (online) 1537-4521
    ISSN 0148-5717
    DOI 10.1097/olq.0000000000001198
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Understanding the Impact of Mpox on Sexual Health Clinical Services: A National Knowledge, Attitudes, and Practices Survey-United States, 2022.

    Schubert, Sara L / Miele, Kathryn / Quilter, Laura A S / Agnew-Brune, Christine / Coor, Alexandra / Kachur, Rachel / Lewis, Felicia / Ard, Kevin L / Wendel, Karen / Anderson, Teri / Nagendra, Gowri / Tromble, Erin

    Sexually transmitted diseases

    2023  Volume 51, Issue 1, Page(s) 38–46

    Abstract: Background: During the 2022 mpox outbreak, most cases were associated with sexual contact, and many people with mpox sought care from sexual health clinics and programs. The National Network of STD Clinical Prevention Training Centers, in partnership ... ...

    Abstract Background: During the 2022 mpox outbreak, most cases were associated with sexual contact, and many people with mpox sought care from sexual health clinics and programs. The National Network of STD Clinical Prevention Training Centers, in partnership with the Centers for Disease Control and Prevention, conducted a survey of US sexual health clinics and programs to assess knowledge, practices, and experiences around mpox to inform a future public health response.
    Methods: Between August 31 and September 13, 2022, the National Network of STD Clinical Prevention Training Centers facilitated a web-based survey. Descriptive statistics were generated in R.
    Results: Among 168 responses by clinicians (n = 131, 78%) and program staff (n = 37, 22%), more than half (51%) reported at least somewhat significant mpox-related clinical disruptions including burdensome paperwork requirements for mpox testing (40%) and tecovirimat use (88%). Long clinic visits (51%) added additional burden, and the median mpox-related visit lasted 1 hour. Few clinicians felt comfortable with advanced pain management, and clinicians felt most uninformed about preexposure (19%) and postexposure (24%) prophylaxis. Of 89 respondents involved in vaccination, 61% reported using equity strategies; however, accounts of these strategies revealed a focus on guideline or risk factor-based screenings instead of equity activities.
    Conclusions: These findings highlight the substantial impact of the 2022 mpox outbreak on sexual health care in the United States. Critical gaps and barriers were identified that may inform additional mpox training and technical assistance, including challenges with testing, diagnosis, and management as well as a disconnect between programs' stated goal of equity and operationalization of strategies to achieve equity.
    MeSH term(s) United States/epidemiology ; Humans ; Health Knowledge, Attitudes, Practice ; Mpox (monkeypox) ; Sexual Health ; Ambulatory Care ; Ambulatory Care Facilities
    Language English
    Publishing date 2023-10-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 435191-5
    ISSN 1537-4521 ; 0148-5717
    ISSN (online) 1537-4521
    ISSN 0148-5717
    DOI 10.1097/OLQ.0000000000001882
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: The Potential Impact & Availability of Sexual Health Services During the COVID-19 Pandemic

    Nagendra, Gowri / Carnevale, Caroline / Neu, Natalie / Cohall, Alwyn / Zucker, Jason

    Sex. transm. dis

    Abstract: As the COVID-19 pandemic causes upheaval in New York City (NYC), one consequence is the accessibility of sexual health services. The NYC STD Prevention Training Center at Columbia University administered an online provider survey to understand how the ... ...

    Abstract As the COVID-19 pandemic causes upheaval in New York City (NYC), one consequence is the accessibility of sexual health services. The NYC STD Prevention Training Center at Columbia University administered an online provider survey to understand how the COVID-19 pandemic is affecting the availability of sexual health care services regionally.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #589624
    Database COVID19

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  6. Article: PAIN MANAGEMENT AMID THE COVID-19 PANDEMICThe Potential Impact and Availability of Sexual Health Services During the COVID-19 Pandemic

    Nagendra, Gowri / Carnevale, Caroline / Neu, Natalie / Cohall, Alwyn / Zucker, Jason

    Topics in Pain Management

    Abstract: As the COVID-19 pandemic causes upheaval in New York City (NYC), 1 consequence is the accessibility of sexual health services The NYC STD Prevention Training Center at Columbia University administered an online provider survey to understand how the COVID- ...

    Abstract As the COVID-19 pandemic causes upheaval in New York City (NYC), 1 consequence is the accessibility of sexual health services The NYC STD Prevention Training Center at Columbia University administered an online provider survey to understand how the COVID-19 pandemic is affecting the availability of sexual health care services regionally
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #604426
    Database COVID19

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  7. Article: The Potential Impact and Availability of Sexual Health Services During the COVID-19 Pandemic

    Nagendra, Gowri / Carnevale, Caroline / Neu, Natalie / Cohall, Alwyn / Zucker, Jason

    Sex Transm Dis

    Abstract: As the COVID-19 pandemic causes upheaval in New York City (NYC), 1 consequence is the accessibility of sexual health services. The NYC STD Prevention Training Center at Columbia University administered an online provider survey to understand how the ... ...

    Abstract As the COVID-19 pandemic causes upheaval in New York City (NYC), 1 consequence is the accessibility of sexual health services. The NYC STD Prevention Training Center at Columbia University administered an online provider survey to understand how the COVID-19 pandemic is affecting the availability of sexual health care services regionally.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #589624
    Database COVID19

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  8. Article ; Online: An Educational Intervention to Improve Provider Screening for Syphilis Among Men Who Have Sex with Men Utilizing an Urban Urgent Care Center.

    Romo, Dina / Nagendra, Gowri / Schechter, Sarah / Pavlish, April / Cohall, Alwyn / Neu, Natalie

    Journal of community health

    2019  Volume 44, Issue 4, Page(s) 822–827

    Abstract: Rates of syphilis are increasing in the United States especially among men who have sex with men (MSM). The purpose of this project was to implement an educational intervention based on the 2015 CDC Sexually Transmitted Diseases (STD) Treatment ... ...

    Abstract Rates of syphilis are increasing in the United States especially among men who have sex with men (MSM). The purpose of this project was to implement an educational intervention based on the 2015 CDC Sexually Transmitted Diseases (STD) Treatment Guidelines for urgent care providers with an emphasis on identifying MSM sexual behavior and appropriate screening for syphilis. An urgent care center was identified as a location where men seek care and where STD testing was occurring. After a baseline provider focus group to identify barriers to STD testing, a patient survey was created and given to clients to increase identification of MSM behaviors and to prompt providers to order syphilis testing. In addition, an educational intervention was implemented to improve provider and staff screening for syphilis. The intervention occurred between September 2015-December 2015. A total of 1341 males were seen with 1067 surveys collected. The mean age was 35.6 and 57.4% were Hispanic. Overall, 72 (5.4%) males identified as MSM. Approximately 50% of all MSM identified had RPRs (n = 37) sent and of these 13.5% (n = 5) tested positive for syphilis. The focus group among urgent care providers and staff identified barriers to syphilis testing. Targeted screening of males using a self-administered questionnaire is acceptable to urgent care populations and may assist in identifying MSM which in turn may help to facilitate syphilis screening and other relevant STI testing pertinent to this population.
    MeSH term(s) Adult ; Ambulatory Care/methods ; Health Personnel/education ; Homosexuality, Male ; Humans ; Male ; Practice Guidelines as Topic ; Surveys and Questionnaires ; Syphilis/diagnosis ; Urban Population
    Language English
    Publishing date 2019-03-15
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 426631-6
    ISSN 1573-3610 ; 0094-5145
    ISSN (online) 1573-3610
    ISSN 0094-5145
    DOI 10.1007/s10900-019-00647-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Novel amide and sulphonamide derivatives of 6-(piperazin-1-yl)phenanthridine as potent Mycobacterium tuberculosis H37Rv inhibitors.

    Naidu, Kalaga Mahalakshmi / Nagesh, Hunsur Nagendra / Singh, Manjeet / Sriram, Dharmarajan / Yogeeswari, Perumal / Gowri Chandra Sekhar, Kondapalli Venkata

    European journal of medicinal chemistry

    2015  Volume 92, Page(s) 415–426

    Abstract: A series of thirty three novel 6-(piperazin-1-yl)phenanthridine amide and sulphonamide analogues were synthesized, characterized and screened for their in vitro antimycobacterial activity against Mycobacterium tuberculosis (MTB) H37Rv strain. These ... ...

    Abstract A series of thirty three novel 6-(piperazin-1-yl)phenanthridine amide and sulphonamide analogues were synthesized, characterized and screened for their in vitro antimycobacterial activity against Mycobacterium tuberculosis (MTB) H37Rv strain. These compounds exhibited minimum inhibitory concentration (MIC) between 1.56 and ≥50 μg/mL. Out of these derivatives, few compounds 6l, 6r, 7b, 7f, 7g and 7k exhibited moderate activity (MIC = 6.25 μg/mL) and compounds 6b, 6e, 6k, 6n, 7h, 7i and 7n displayed good activity (MIC = 3.13 μg/mL), whereas compounds 6m, 6s and 7d exhibited excellent anti-tubercular activity (MIC = 1.56 μg/mL). In addition, MTT assay was accomplished on the active analogues of the series against mouse macrophage (RAW 264.7) cells to evaluate the toxicity profile of the newly synthesized compounds and selectivity index of the compounds was determined. Additionally, compounds 6b and 7d were docked to the ATPase domain of M. tuberculosis GyrB protein to know the interaction profile and structures of compounds 6b and 7d were further substantiated through single crystal XRD.
    MeSH term(s) Amides/chemical synthesis ; Amides/chemistry ; Amides/pharmacology ; Animals ; Antitubercular Agents/chemical synthesis ; Antitubercular Agents/chemistry ; Antitubercular Agents/pharmacology ; Cell Line ; Crystallography, X-Ray ; Dose-Response Relationship, Drug ; Enzyme Inhibitors/chemical synthesis ; Enzyme Inhibitors/chemistry ; Enzyme Inhibitors/pharmacology ; Hydrolases/antagonists & inhibitors ; Hydrolases/metabolism ; Macrophages/drug effects ; Mice ; Microbial Sensitivity Tests ; Models, Molecular ; Molecular Structure ; Mycobacterium tuberculosis/drug effects ; Mycobacterium tuberculosis/enzymology ; Phenanthridines/chemical synthesis ; Phenanthridines/chemistry ; Phenanthridines/pharmacology ; Piperazines/chemical synthesis ; Piperazines/chemistry ; Piperazines/pharmacology ; Structure-Activity Relationship
    Chemical Substances 6-(piperazin-1-yl)phenanthridine ; Amides ; Antitubercular Agents ; Enzyme Inhibitors ; Phenanthridines ; Piperazines ; Hydrolases (EC 3.-) ; HsaD protein, Mycobacterium tuberculosis (EC 3.7.-)
    Language English
    Publishing date 2015-03-06
    Publishing country France
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 188597-2
    ISSN 1768-3254 ; 0009-4374 ; 0223-5234
    ISSN (online) 1768-3254
    ISSN 0009-4374 ; 0223-5234
    DOI 10.1016/j.ejmech.2015.01.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Multicomponent cascade reaction: dual role of copper in the synthesis of 1,2,3-triazole tethered benzimidazo[1,2-a]quinoline and their photophysical studies

    Nagesh, Hunsur Nagendra / Suresh, Amaroju / Reddy, Muthyala Nagarjuna / Suresh, Narva / Subbalakshmi, Jayanty / Chandra Sekhar, Kondapalli Venkata Gowri

    RSC advances. 2016 Feb. 08, v. 6, no. 19

    2016  

    Abstract: One-pot synthesis of 1,2,3-triazole tethered benzimidazo[1,2-a]quinolines through a multi-component reaction is demonstrated. The domino/cascade reaction proceeds via click reaction, in which 1,2,3-triazole motif augment methylene group reactivity/N–C ... ...

    Abstract One-pot synthesis of 1,2,3-triazole tethered benzimidazo[1,2-a]quinolines through a multi-component reaction is demonstrated. The domino/cascade reaction proceeds via click reaction, in which 1,2,3-triazole motif augment methylene group reactivity/N–C bond formation/Knoevenagel condensation in sequence. Overall one C–C bond and three C–N bonds are formed in a single step. In addition, photophysical properties of these new compounds were studied and compound 5u emerged as good fluorogenic substrate with quantum yield ∼0.21.
    Keywords chemical bonding ; condensation reactions ; copper ; quinoline ; synthesis ; triazoles
    Language English
    Dates of publication 2016-0208
    Size p. 15884-15894.
    Publishing place The Royal Society of Chemistry
    Document type Article
    ISSN 2046-2069
    DOI 10.1039/c5ra24048d
    Database NAL-Catalogue (AGRICOLA)

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