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  1. Article ; Online: Hand and Foot Color Change: Diagnosis and Management.

    Fleck, Dustin E / Hoeltzel, Mark F

    Pediatrics in review

    2017  Volume 38, Issue 11, Page(s) 511–519

    MeSH term(s) Child ; Color ; Cyanosis/diagnosis ; Cyanosis/etiology ; Cyanosis/therapy ; Diagnosis, Differential ; Erythromelalgia/diagnosis ; Erythromelalgia/etiology ; Erythromelalgia/therapy ; Foot Diseases/diagnosis ; Foot Diseases/etiology ; Foot Diseases/therapy ; Hand ; Humans ; Raynaud Disease/diagnosis ; Raynaud Disease/etiology ; Raynaud Disease/therapy
    Language English
    Publishing date 2017-11
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 774515-1
    ISSN 1526-3347 ; 0191-9601
    ISSN (online) 1526-3347
    ISSN 0191-9601
    DOI 10.1542/pir.2016-0234
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Lost at Sea in Search of a Diagnosis: A Case of Unexplained Bleeding.

    Amos, Lauren E / Carpenter, Shannon L / Hoeltzel, Mark F

    Pediatric blood & cancer

    2016  Volume 63, Issue 7, Page(s) 1305–1306

    Abstract: Scurvy results from a dietary deficiency of vitamin C (ascorbic acid) and is rarely thought of in modern day medicine. It now almost always occurs in pediatric patients with behavioral diagnoses, nutritionally restricted diets, and food allergies. ... ...

    Abstract Scurvy results from a dietary deficiency of vitamin C (ascorbic acid) and is rarely thought of in modern day medicine. It now almost always occurs in pediatric patients with behavioral diagnoses, nutritionally restricted diets, and food allergies. Symptoms of scurvy include ecchymoses, bleeding gums, and arthralgias. Here, we present a 17-year-old male with autism spectrum disorder and a diet severely deficient in ascorbic acid due to textural aversion and food preferences. He presented with recurrent arthritis, hemarthrosis, bruising, and anemia. His vitamin C level was low, and his symptoms improved promptly after treatment with ascorbic acid.
    MeSH term(s) Adolescent ; Ascorbic Acid/administration & dosage ; Autism Spectrum Disorder ; Hemorrhage/diagnosis ; Hemorrhage/drug therapy ; Hemorrhage/pathology ; Humans ; Male ; Scurvy/diagnosis ; Scurvy/drug therapy ; Scurvy/pathology
    Chemical Substances Ascorbic Acid (PQ6CK8PD0R)
    Language English
    Publishing date 2016
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2131448-2
    ISSN 1545-5017 ; 1545-5009
    ISSN (online) 1545-5017
    ISSN 1545-5009
    DOI 10.1002/pbc.25980
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Pansclerotic morphea with features of eosinophilic fasciitis: distinct entities or part of a continuum?

    Odhav, Ashika / Hoeltzel, Mark F / Canty, Kristi

    Pediatric dermatology

    2014  Volume 31, Issue 2, Page(s) e42–7

    Abstract: Scleroderma is a highly complex disorder in its clinical manifestations and pathogenesis. It has a wide range of clinical manifestations due to varying degrees of vasculopathy, autoimmunity, altered endothelium function, and abnormal fibrosis. The most ... ...

    Abstract Scleroderma is a highly complex disorder in its clinical manifestations and pathogenesis. It has a wide range of clinical manifestations due to varying degrees of vasculopathy, autoimmunity, altered endothelium function, and abnormal fibrosis. The most widely used classification system grouped eosinophilic fasciitis and disabling pansclerotic morphea of childhood into the category of deep morphea. This previous classification does not include a category for overlapping conditions. A proposed new classification includes a new mixed subtype in which a combination of two or more of the previous subtypes is present in the same individual, although eosinophilic fasciitis has been excluded. We present the case of a 4-year-old boy who presented with features of disabling pansclerotic morphea and eosinophilic fasciitis simultaneously, which to our knowledge has not been previously reported. This suggests that these diseases are part of a more closely related continuum rather than separate disorders, as currently classified.
    MeSH term(s) Child, Preschool ; Diagnosis, Differential ; Drug Therapy, Combination ; Eosinophilia/diagnosis ; Eosinophilia/drug therapy ; Eosinophilia/pathology ; Fasciitis/diagnosis ; Fasciitis/drug therapy ; Fasciitis/pathology ; Glucocorticoids/therapeutic use ; Humans ; Immunosuppressive Agents/therapeutic use ; Male ; Scleroderma, Localized/diagnosis ; Scleroderma, Localized/drug therapy ; Scleroderma, Localized/pathology
    Chemical Substances Glucocorticoids ; Immunosuppressive Agents
    Language English
    Publishing date 2014-03
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 605539-4
    ISSN 1525-1470 ; 0736-8046
    ISSN (online) 1525-1470
    ISSN 0736-8046
    DOI 10.1111/pde.12279
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Picture of the month--a case of neonatal lupus erythematosus and associated hepatitis.

    Adil, Hala F / Horii, Kimberly A / Hoeltzel, Mark F

    Archives of pediatrics & adolescent medicine

    2012  Volume 166, Issue 3, Page(s) 283–284

    MeSH term(s) Humans ; Infant ; Liver Function Tests ; Lupus Erythematosus, Systemic/blood ; Lupus Erythematosus, Systemic/congenital ; Lupus Erythematosus, Systemic/diagnosis ; Lupus Erythematosus, Systemic/immunology ; Lupus Erythematosus, Systemic/therapy ; Male
    Language English
    Publishing date 2012-03
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 1179374-0
    ISSN 1538-3628 ; 1072-4710
    ISSN (online) 1538-3628
    ISSN 1072-4710
    DOI 10.1001/archpediatrics.2011.789a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The presentation, assessment, pathogenesis, and treatment of calcinosis in juvenile dermatomyositis.

    Hoeltzel, Mark F / Oberle, Edward J / Robinson, Angela Byun / Agarwal, Arunima / Rider, Lisa G

    Current rheumatology reports

    2014  Volume 16, Issue 12, Page(s) 467

    Abstract: Calcinosis is one of the hallmark sequelae of juvenile dermatomyositis (JDM), and despite recent ...

    Abstract Calcinosis is one of the hallmark sequelae of juvenile dermatomyositis (JDM), and despite recent progress in the therapy of JDM, dystrophic calcification still occurs in approximately one third of patients. This review discusses our current, albeit limited, understanding of risk factors for the development of calcinosis in JDM, as well as approaches to assessment, and current views on its pathogenesis. Anecdotal approaches to treating calcinosis associated with JDM, including both anti-inflammatory therapies and agents aimed at inhibiting the deposition of calcium hydroxyapatite, are reviewed. An improved understanding of the pathogenesis of calcinosis, the establishment of standardized measurement tools to assess calcinosis, and randomized controlled trials employing more sensitive outcome measures are needed to develop efficacious therapies for this often disabling complication.
    MeSH term(s) Anti-Inflammatory Agents/therapeutic use ; Calcinosis/diagnosis ; Calcinosis/drug therapy ; Calcinosis/etiology ; Dermatomyositis/complications ; Humans
    Chemical Substances Anti-Inflammatory Agents
    Language English
    Publishing date 2014-11-03
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Intramural ; Review
    ZDB-ID 2057357-1
    ISSN 1534-6307 ; 1523-3774
    ISSN (online) 1534-6307
    ISSN 1523-3774
    DOI 10.1007/s11926-014-0467-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Diagnostic evaluation and medication usage in a cohort of subjects with juvenile dermatomyositis from the CARRAnet registry

    Robinson Angela B / Hoeltzel Mark F / Reed Ann M / Huber Adam / Feldman Brian M

    Pediatric Rheumatology, Vol 10, Iss Suppl 1, p A

    2012  Volume 64

    Keywords Diseases of the musculoskeletal system ; RC925-935 ; Specialties of internal medicine ; RC581-951 ; Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Internal medicine ; DOAJ:Medicine (General) ; DOAJ:Health Sciences ; Pediatrics ; RJ1-570 ; DOAJ:Pediatrics
    Language English
    Publishing date 2012-07-01T00:00:00Z
    Publisher BioMed Central
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Comparison of idiopathic and secondary uveitis patients seen in a dual pediatric rheumatology-ophthalmology clinic

    Rizk Victoria TE / Becker Mara L / Hoeltzel Mark F / Olitsky Scott E / Lasky Andrew

    Pediatric Rheumatology, Vol 10, Iss Suppl 1, p A

    2012  Volume 80

    Keywords Diseases of the musculoskeletal system ; RC925-935 ; Specialties of internal medicine ; RC581-951 ; Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Internal medicine ; DOAJ:Medicine (General) ; DOAJ:Health Sciences ; Pediatrics ; RJ1-570 ; DOAJ:Pediatrics
    Language English
    Publishing date 2012-07-01T00:00:00Z
    Publisher BioMed Central
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Intracellular folate concentrations in Down syndrome patients with arthritis

    Becker Mara L / van Haandel Leon / Talib Nasreen / Lasky Andrew / Hoeltzel Mark F / Leeder J

    Pediatric Rheumatology, Vol 10, Iss Suppl 1, p A

    2012  Volume 52

    Keywords Diseases of the musculoskeletal system ; RC925-935 ; Specialties of internal medicine ; RC581-951 ; Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Internal medicine ; DOAJ:Medicine (General) ; DOAJ:Health Sciences ; Pediatrics ; RJ1-570 ; DOAJ:Pediatrics
    Language English
    Publishing date 2012-07-01T00:00:00Z
    Publisher BioMed Central
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Race is a risk factor for calcinosis in patients with JDM – early results from the CARRAnet registry study

    Hoeltzel Mark F / Becker Mara L / Robinson Angela B / Feldman Brian M / Huber Adam / Reed Ann M

    Pediatric Rheumatology, Vol 10, Iss Suppl 1, p A

    2012  Volume 65

    Keywords Diseases of the musculoskeletal system ; RC925-935 ; Specialties of internal medicine ; RC581-951 ; Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Internal medicine ; DOAJ:Medicine (General) ; DOAJ:Health Sciences ; Pediatrics ; RJ1-570 ; DOAJ:Pediatrics
    Language English
    Publishing date 2012-07-01T00:00:00Z
    Publisher BioMed Central
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Clinical characteristics of children with juvenile dermatomyositis recruited within the first 7 months of the CARRAnet registry

    Hoeltzel Mark F / Becker Mara L / Robinson Angela B / Feldman Brian M / Huber Adam / Reed Ann M

    Pediatric Rheumatology, Vol 10, Iss Suppl 1, p A

    2012  Volume 12

    Keywords Diseases of the musculoskeletal system ; RC925-935 ; Specialties of internal medicine ; RC581-951 ; Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Internal medicine ; DOAJ:Medicine (General) ; DOAJ:Health Sciences ; Pediatrics ; RJ1-570 ; DOAJ:Pediatrics
    Language English
    Publishing date 2012-07-01T00:00:00Z
    Publisher BioMed Central
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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