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Article ; Online: A clinician's guide to gallstones and common bile duct (CBD): A study protocol for a systematic review and evidence-based recommendations.

Sebghatollahi, Vahid / Parsa, Mohammadreza / Minakari, Mohammad / Azadbakht, Saleh

Health science reports

2023 Volume 6, Issue 9, Page(s) e1555

Abstract: Background and aims: Gallstones are one of the most common and costly diseases of the gastrointestinal tract and occur when a combination of deposits consisting of fat or minerals accumulate in the gallbladder or common bile duct (CBD). This paper ... ...

Abstract	Background and aims: Gallstones are one of the most common and costly diseases of the gastrointestinal tract and occur when a combination of deposits consisting of fat or minerals accumulate in the gallbladder or common bile duct (CBD). This paper provides a comprehensive review of gallstone epidemiology, diagnosis, and management, focusing on current clinical guidelines and evidence-based approaches. Methods: A systematic literature review gathered information from various sources, including PubMed, Trip, Google Scholar, Clinical Key, and reputable medical association websites. Keywords related to gallstones, CBD stones, cholelithiasis, choledocholithiasis, and guidelines were used to extract relevant recommendations. Expert consultations and consensus meetings localized the recommendations based on the target population and available resources. Results: The paper discusses demographic factors, dietary habits, and lifestyle influences contributing to gallstone formation. Gallstones are categorized into cholesterol and pigment types, with varying prevalences across regions. Many individuals with gallstones remain asymptomatic, but complications can lead to serious and potentially life-threatening conditions. Diagnosis relies on history, physical examination, laboratory tests, and transabdominal ultrasound. Specific predictive factors help categorize patients into high, moderate, or low probability groups for CBD stones. Conclusion: Evidence-based recommendations for gallstone diagnosis and management are presented, emphasizing individualized treatment plans. Surgical interventions, nonsurgical treatments like oral litholysis with UDCA, and stenting are discussed. The management of gallstones in pregnant women is also addressed, considering the potential risks and appropriate treatment options during pregnancy.
Language	English
Publishing date	2023-09-12
Publishing country	United States
Document type	Journal Article
ISSN	2398-8835
ISSN (online)	2398-8835
DOI	10.1002/hsr2.1555
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Hyponatremia-induced generalized seizure after taking polyethylene glycol for colon preparation-A case report and brief review of the literature.

Seyrafian, Shiva / Sebghatollahi, Vahid / Bastani, Bahar

Clinical case reports

2022 Volume 10, Issue 8, Page(s) e6247

Abstract: Severe hyponatremia is life-threatening in hospitalized patients. We present an elderly female who developed severe hyponatremia, seizure, and loss of consciousness after taking polyethylene glycol (PEG) solution before colonoscopy. The risk of ... ...

Abstract	Severe hyponatremia is life-threatening in hospitalized patients. We present an elderly female who developed severe hyponatremia, seizure, and loss of consciousness after taking polyethylene glycol (PEG) solution before colonoscopy. The risk of hyponatremia with PEG for colon preparation in elderly susceptible patients is high. We review the relevant literature.
Language	English
Publishing date	2022-08-26
Publishing country	England
Document type	Case Reports
ZDB-ID	2740234-4
ISSN	2050-0904
ISSN	2050-0904
DOI	10.1002/ccr3.6247
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Article ; Online: A clinician's guide to gallstones and common bile duct (CBD)

Vahid Sebghatollahi / Mohammadreza Parsa / Mohammad Minakari / Saleh Azadbakht

Health Science Reports, Vol 6, Iss 9, Pp n/a-n/a (2023)

A study protocol for a systematic review and evidence‐based recommendations

2023

Abstract: Abstract Background and Aims Gallstones are one of the most common and costly diseases of the gastrointestinal tract and occur when a combination of deposits consisting of fat or minerals accumulate in the gallbladder or common bile duct (CBD). This ... ...

Abstract	Abstract Background and Aims Gallstones are one of the most common and costly diseases of the gastrointestinal tract and occur when a combination of deposits consisting of fat or minerals accumulate in the gallbladder or common bile duct (CBD). This paper provides a comprehensive review of gallstone epidemiology, diagnosis, and management, focusing on current clinical guidelines and evidence‐based approaches. Methods A systematic literature review gathered information from various sources, including PubMed, Trip, Google Scholar, Clinical Key, and reputable medical association websites. Keywords related to gallstones, CBD stones, cholelithiasis, choledocholithiasis, and guidelines were used to extract relevant recommendations. Expert consultations and consensus meetings localized the recommendations based on the target population and available resources. Results The paper discusses demographic factors, dietary habits, and lifestyle influences contributing to gallstone formation. Gallstones are categorized into cholesterol and pigment types, with varying prevalences across regions. Many individuals with gallstones remain asymptomatic, but complications can lead to serious and potentially life‐threatening conditions. Diagnosis relies on history, physical examination, laboratory tests, and transabdominal ultrasound. Specific predictive factors help categorize patients into high, moderate, or low probability groups for CBD stones. Conclusion Evidence‐based recommendations for gallstone diagnosis and management are presented, emphasizing individualized treatment plans. Surgical interventions, nonsurgical treatments like oral litholysis with UDCA, and stenting are discussed. The management of gallstones in pregnant women is also addressed, considering the potential risks and appropriate treatment options during pregnancy.
Keywords	bile duct ; cholecystectomy ; endoscopic ; gallbladder ; gallstones ; Medicine ; R
Subject code	610
Language	English
Publishing date	2023-09-01T00:00:00Z
Publisher	Wiley
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Hyponatremia‐induced generalized seizure after taking polyethylene glycol for colon preparation—A case report and brief review of the literature

Shiva Seyrafian / Vahid Sebghatollahi / Bahar Bastani

Clinical Case Reports, Vol 10, Iss 8, Pp n/a-n/a (2022)

2022

Abstract: Abstract Severe hyponatremia is life‐threatening in hospitalized patients. We present an elderly female who developed severe hyponatremia, seizure, and loss of consciousness after taking polyethylene glycol (PEG) solution before colonoscopy. The risk of ... ...

Abstract	Abstract Severe hyponatremia is life‐threatening in hospitalized patients. We present an elderly female who developed severe hyponatremia, seizure, and loss of consciousness after taking polyethylene glycol (PEG) solution before colonoscopy. The risk of hyponatremia with PEG for colon preparation in elderly susceptible patients is high. We review the relevant literature.
Keywords	colonoscopy ; hyponatremia ; polyethylene glycol ; seizure ; Medicine ; R ; Medicine (General) ; R5-920
Language	English
Publishing date	2022-08-01T00:00:00Z
Publisher	Wiley
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Correlation of Treatment of Peptic Ulcer Bleeding by Argon Plasma Coagulation (APC) via Contact Heat Probe Method (heater probe) with Epinephrine Injection.

Sebghatollahi, Vahid / Minakari, Mohammad / Tamizifar, Babak / Ebrahimi, Amrollah / Dashti, Gholam Reza

Middle East journal of digestive diseases

2021 Volume 12, Issue 4, Page(s) 271–277

Abstract: BACKGROUND This clinical investigation aimed to compare the efficacy of treatment of peptic ulcer hemorrhage by argon plasma coagulation (APC) via contact heat probe method (heater probe) along with epinephrine injection. METHODS 100 patients who ... ...

Abstract	BACKGROUND This clinical investigation aimed to compare the efficacy of treatment of peptic ulcer hemorrhage by argon plasma coagulation (APC) via contact heat probe method (heater probe) along with epinephrine injection. METHODS 100 patients who underwent endoscopic treatment, were randomly divided into two groups consisting of 50 patients each. In the first group, an intervention was performed using foot pedal and 2.3 mm and 3.2 mm argon probes placed in a 2 to 8 mm distance of delivery place leading to plasma coagulation, sufficient necrosis and hemostasis. In the second group, wound press contact probe was used for wound healing with 15 watts of heat for about 25 degrees, causing coagulation and hemostasis. To evaluate and compare the ulcer treatment in both groups, the patient progress results were monitored for a period of one month from the day of discharge. Statistical analyses of data were performed using SPSS software version 22 along with Chi-square test and T-test. RESULTS No significant difference observed in two groups in term of age, sex and clinical symptoms, but patients treated with APC method had higher hemoglobin levels (
Language	English
Publishing date	2021-01-25
Publishing country	Iran
Document type	Journal Article
ZDB-ID	2623796-9
ISSN	2008-5249 ; 2008-5230
ISSN (online)	2008-5249
ISSN	2008-5230
DOI	10.34172/mejdd.2020.193
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Article: Serum amylase and lipase levels for prediction of postendoscopic retrograde cholangiopancreatography pancreatitis.

Minakari, Mohammad / Sebghatollahi, Vahid / Sattari, Maryam / Fahami, Elaheh

Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences

2018 Volume 23, Page(s) 54

Abstract: Background: The aim of the present study was to assess 2- and 4-h postendoscopic retrograde cholangiopancreatography (ERCP) serum amylase and lipase levels for prediction of post-ERCP, pancreatitis (PEP), and their predictive cutoff values.: Materials ...

Abstract	Background: The aim of the present study was to assess 2- and 4-h postendoscopic retrograde cholangiopancreatography (ERCP) serum amylase and lipase levels for prediction of post-ERCP, pancreatitis (PEP), and their predictive cutoff values. Materials and methods: In this cross-sectional study, we evaluated serum amylase and lipase levels before the procedure, 2 h and 4 h after the procedure, and in patients with persisting abdominal pain, 24 h afterward. A total of 300 adult patients who underwent ERCP procedures from March 2014 to June 2015 in referral hospital in Isfahan were studied. The receiver operating characteristic analysis was applied to determine the predictive score of amylase and lipase levels for PEP 2 and 4 h after ERCP. Results: The 2-h serum amylase cutoff values of 241 IU/L (normal range: 28-100 IU/L) had a very high negative predictive value (NPV) (98.7%) but a poor positive predictive value (49.2%) for prediction of PEP (area under curve [AUC]: 0.947; 95% confidence interval [CI]: 0.914-0.979). Based on our results, the patients might be considered for supportive therapy of PEP with the 4-h serum amylase above the cut point of 839.5 IU/L with a specificity of 95.1% (AUC: 0.978; 95% CI: 0.964-0.992). In addition, the 2- and 4-h serum lipase levels at cut points of 216 IU/L (AUC: 0.954; 95% CI: 0.931-0.977) and 656.5 IU/L (AUC: 0.966; 95% CI: 0.945-0.986) (normal value <60 IU/L), respectively, had the best sensitivity (97.1%) and high NPVs (99.6%) for exclusion of PEP. Conclusion: Measurements of serum amylase and lipase 2- and 4-h post-ERCP might be useful in prediction of PEP.
Language	English
Publishing date	2018-06-06
Publishing country	India
Document type	Journal Article
ZDB-ID	2513029-8
ISSN	1735-7136 ; 1735-1995
ISSN (online)	1735-7136
ISSN	1735-1995
DOI	10.4103/jrms.JRMS_1100_17
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Article ; Online: Comparison of Self-Coherence and Impulsiveness between People with Irritable Bowel Syndrome and Healthy People

Saeideh Khaki / Hajar Torkan / Vahid Sebghatollahi

Social Behavior Research & Health, Vol 3, Iss 1, Pp 340-

2019 Volume 348

Abstract: Background: Irritable Bowel Syndrome (IBS) is a serious syndrome, which damages people’s psychological, communicative, social, and emotional lives. Therefore, the present study was conducted to compare integrative self-knowledge and impulsivity in ... ...

Abstract	Background: Irritable Bowel Syndrome (IBS) is a serious syndrome, which damages people’s psychological, communicative, social, and emotional lives. Therefore, the present study was conducted to compare integrative self-knowledge and impulsivity in patients with Irritable IBS and healthy individuals. Methods: This case-control study was conducted on patients with IBS referring to gastroenterologists and healthy individuals in the city of Isfahan in 2018. The sample size included 150 patients with IBS and 150 healthy people in Isfahan selected using non-random convenient sampling method. The integrative self-knowledge and impulsivity questionnaires were applied to collect the information. After collecting the questionnaires and extracting the raw data, SPSS23 software was used and t-test was run to analyze the data. Results: A significant difference was observed between patients with IBS and healthy participants with regard to integrative self-knowledge and impulsivity (P-value < 0.001), so that people with IBS had lower integrative self-knowledge and higher impulsivity in comparison with the healthy individuals. Conclusion: According to the findings, people with IBS had lower integrative self-knowledge and higher impulsivity due to their therapeutic and psychological involvement in the disease. So, third-wave psychological treatments such as mindfulness treatment and positivist psychotherapy are required in this area.
Keywords	Integrative Self-Knowledge ; Impulsivity ; Irritable Bowel Syndrome (IBS) ; Social Sciences ; H
Subject code	150
Language	English
Publishing date	2019-06-01T00:00:00Z
Publisher	Shahid Sadoughi University of Medical Sciences
Document type	Article ; Online
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Article ; Online: The Efficacy of Levofloxacin versus Clarithromycin in Primary Quadruple Therapy for the Eradication of Helicobacter Pylori

Vahid Sebghatollahi / Reyhaneh Hosseini / Babak Tamizifar / Mohammad Minakari / Maryam Soheilipour

مجله دانشکده پزشکی اصفهان, Vol 38, Iss 569, Pp 186-

A Prospective Randomized Controlled Clinical Trial Study

2020 Volume 192

Abstract: Background: Helicobacter pylori (H. pylori) infection is prevalent in the world. Resistance to antibiotics is the main reason for treatment failure. This clinical trial examined the effect of clarithromycin versus levofloxacin as the content of first ... ...

Abstract	Background: Helicobacter pylori (H. pylori) infection is prevalent in the world. Resistance to antibiotics is the main reason for treatment failure. This clinical trial examined the effect of clarithromycin versus levofloxacin as the content of first line of treatment of the patients with peptic ulcer. Methods: In this double-blind randomized controlled clinical trial study with parallel groups, 148 infected patients by H. pylori who had been proven during endoscopic biopsy were randomly divided into two equal groups. One group was treated with the quadruple therapy of clarithromycin 500 mg BID, amoxicillin 1 g BID, bismuth subcitrate 240 mg BID, and pantazole 40 mg BID. The second group was treated with levofloxacin 500 mg QD, amoxicillin 1 g BID, bismuth subcitrate 240 mg BID, and pantazole 40 mg BID. The duration of treatment was 14 days in both groups and four weeks after treatment, the eradication rate was assessed using the stool antigen test. Findings: The eradication rate was significantly higher using regime containing clarithromycin than that of levofloxacin [81.1%; confidence interval of 95% (95%CI): 72.2%-89.9% vs. 60.3%; 95%CI: 49.3%-72.2%; P = 0.021). The improvement in quality of life in patients treated with clarithromycin was comparable with levofloxacin (7.90 ± 5.79 vs. 9.27 ± 5.89; P = 0.18). Adverse effects were different between the groups in which bad taste was reported more frequently in clarithromycin than levofloxacin (27.0% vs. 4.3%) while epigastric pain was more in levofloxacin (7.1% vs. 2.7%). Conclusion: The effectiveness of clarithromycin on H. pylori eradication rate was significantly higher than levofloxacin.
Keywords	helicobacter pylori ; clarithromycin ; levofloxacin ; Medicine ; R ; Medicine (General) ; R5-920
Subject code	610
Language	Persian
Publishing date	2020-06-01T00:00:00Z
Publisher	Vesnu Publications
Document type	Article ; Online
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Article: Association of irritable bowel syndrome and sleep apnea in patients referred to sleep laboratory.

Ghiasi, Farzin / Amra, Babak / Sebghatollahi, Vahid / Azimian, Fatemeh

Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences

2017 Volume 22, Page(s) 72

Abstract: Background: Irritable bowel syndrome (IBS) is assumed as one of the most frequent gastrointestinal disorders, which decreases the patient's quality of life. IBS pathogenesis, however, is not clearly defined. It seems that sleep apnea induces or ... ...

Abstract	Background: Irritable bowel syndrome (IBS) is assumed as one of the most frequent gastrointestinal disorders, which decreases the patient's quality of life. IBS pathogenesis, however, is not clearly defined. It seems that sleep apnea induces or escalates IBS clinical symptoms. This study aims at evaluating of IBS prevalence in patients, who are afflicted or are not afflicted with sleep apnea. Materials and methods: This was a case-control study, which was implemented in a sleep laboratory located in Isfahan, Iran. We recruited 200 patients being more than 15 years from 2014 to 2015. Based on the apnea-hypopnea index (AHI), we recruited 100 patients in each of two groups: negative sleep apnea (NSA) (AHI ≤4) and positive sleep apnea (PSA) (AHI >4). IBS was diagnosed through a Rome III diagnostic questionnaire. Results: Overall, the prevalence of IBS among patients referred to sleep laboratory was 17.6%. Indeed, IBS prevalence in NSA and PSA groups were 8.2% and 27.1%, respectively. Furthermore, odds ratio of IBS in PSA group versus NSA was 3.92 (95% confidence interval = 1.58-9.77, Conclusion: This study showed that there was a positive association between sleep apnea and IBS.
Language	English
Publishing date	2017-06-21
Publishing country	India
Document type	Journal Article
ZDB-ID	2513029-8
ISSN	1735-7136 ; 1735-1995
ISSN (online)	1735-7136
ISSN	1735-1995
DOI	10.4103/jrms.JRMS_523_16
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Article ; Online: Etiology and outcome in patients with upper gastrointestinal bleeding: Study on 4747 patients in the central region of Iran.

Minakari, Mohammad / Badihian, Shervin / Jalalpour, Pooyan / Sebghatollahi, Vahid

Journal of gastroenterology and hepatology

2017 Volume 32, Issue 4, Page(s) 789–796

Abstract: Background and aim: Upper gastrointestinal bleeding (UGIB) is a threatening condition leading to urgent hospitalization. This study aims to investigate etiology and outcome in UGIB patients in Iran.: Methods: Medical records of GIB patients admitted ... ...

Abstract	Background and aim: Upper gastrointestinal bleeding (UGIB) is a threatening condition leading to urgent hospitalization. This study aims to investigate etiology and outcome in UGIB patients in Iran. Methods: Medical records of GIB patients admitted to Alzahra referral hospital (in Isfahan) during 2010-2015 were retrospectively reviewed for demographic data, comorbidities, history of smoking and taking non-steroidal anti-inflammatory drugs (NSAIDs), presenting symptoms, endoscopic findings, therapeutic endoscopy, blood products' infusion, surgical intervention, rebleeding, and mortality. Results: A total of 4747 patients were enrolled in the study (69.2% men, mean age = 55.46 ± 21.98 years). Hematemesis was the most frequent presenting symptom (63.5%). Peptic ulcer (duodenal ulcer in most cases) was seen as the main reason for UGIB (42.4%). Rebleeding (present in 16.5% of patients) was found to be more frequent in patients with older age, presenting sign of hematochezia and hypotension, history of taking NSAIDs and smoking, presence of comorbidities, history of bleeding because of UGI tract neoplasm and esophageal varices, history of needing blood products' infusion, and history of therapeutic endoscopy or surgical intervention (P < 0.005). We found that mortality (5.5% in total) was also higher in the same group of patients that were seen to have a higher tendency for rebleeding (P < 0.005). Conclusion: Peptic ulcers are the most common cause of UGIB. Comorbidities, hemodynamic instability, high-risk endoscopic stigmata, history of smoking and taking NSAIDs, gastric and esophageal malignancies, may be important predisposing factors for rebleeding and mortality in patients with UGIB.
MeSH term(s)	Adult ; Age Factors ; Aged ; Anti-Inflammatory Agents, Non-Steroidal/adverse effects ; Comorbidity ; Endoscopy, Gastrointestinal ; Esophageal and Gastric Varices ; Female ; Gastrointestinal Hemorrhage/epidemiology ; Gastrointestinal Hemorrhage/etiology ; Gastrointestinal Hemorrhage/mortality ; Gastrointestinal Neoplasms ; Hematemesis/etiology ; Humans ; Iran/epidemiology ; Male ; Middle Aged ; Peptic Ulcer/complications ; Prognosis ; Recurrence ; Smoking/adverse effects
Chemical Substances	Anti-Inflammatory Agents, Non-Steroidal
Language	English
Publishing date	2017-04
Publishing country	Australia
Document type	Journal Article
ZDB-ID	632882-9
ISSN	1440-1746 ; 0815-9319
ISSN (online)	1440-1746
ISSN	0815-9319
DOI	10.1111/jgh.13617
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