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  1. Article: Potential Uses of

    Subramanian, Murukesan / Selvaraj, Kishore Kumar / Jagannathan, Raghunathan / Rajendran, Swaminathan / Rajendran, Deepika / Madapusi, Balaji Thodur

    Journal of pharmacy & bioallied sciences

    2023  Volume 15, Issue Suppl 1, Page(s) S40–S45

    Abstract: Plaque control, pain control, and modulation of inflammatory mediators to accelerate or stabilize tooth movements are hot issues in orthodontics. The recent advent of phytochemicals as biological mediators has opened new vistas in the aforementioned ... ...

    Abstract Plaque control, pain control, and modulation of inflammatory mediators to accelerate or stabilize tooth movements are hot issues in orthodontics. The recent advent of phytochemicals as biological mediators has opened new vistas in the aforementioned areas of orthodontics.
    Language English
    Publishing date 2023-07-05
    Publishing country India
    Document type Journal Article ; Review
    ZDB-ID 2573569-X
    ISSN 0975-7406 ; 0976-4879
    ISSN (online) 0975-7406
    ISSN 0976-4879
    DOI 10.4103/jpbs.jpbs_74_23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Potential uses of Adhatoda Vasica in orthodontics

    Murukesan Subramanian / Kishore Kumar Selvaraj / Raghunathan Jagannathan / Swaminathan Rajendran / Deepika Rajendran / Balaji Thodur Madapusi

    Journal of Pharmacy and Bioallied Sciences, Vol 15, Iss 5, Pp 40-

    2023  Volume 45

    Abstract: Plaque control, pain control, and modulation of inflammatory mediators to accelerate or stabilize tooth movements are hot issues in orthodontics. The recent advent of phytochemicals as biological mediators has opened new vistas in the aforementioned ... ...

    Abstract Plaque control, pain control, and modulation of inflammatory mediators to accelerate or stabilize tooth movements are hot issues in orthodontics. The recent advent of phytochemicals as biological mediators has opened new vistas in the aforementioned areas of orthodontics. Adhatoda vasica has caught the attention of investigators due to multiple properties related to orthodontics. This study addresses the potential areas of use of A. vasica in orthodontics, which provide ideas for further investigations. A. vasica possesses antibacterial activity, antifungal activity, anti-oxidant effect, anti-inflammatory activity, analgesic effect, osteogenic, and osteoclastic activities. A. vasica has huge potential in orthodontics, whereas all these vistas need careful and methodical testing before use in clinical orthodontics. In the future, investigators can focus on these aspects of the use of A. vasica to develop products.
    Keywords adhatoda vasica ; anti-inflammatory ; orthodontics ; plaque control ; tooth movement ; Pharmacy and materia medica ; RS1-441 ; Analytical chemistry ; QD71-142
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher Wolters Kluwer Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Effect of non-surgical periodontal therapy on CD14 + CD16+ monocyte counts in peripheral blood samples: a clinical interventional study.

    Jagannathan, Raghunanthan / Balaji, Thodur Madapusi / Rao, Suresh Ranga / Alosaimi, Meshal Saleh / Patil, Shankargouda / Siurkel, Yuliia / Cicciù, Marco / Minervini, Giuseppe

    BMC oral health

    2024  Volume 24, Issue 1, Page(s) 94

    Abstract: Monocytes and their macrophage progeny are thought to be involved in tissue and alveolar bone destruction in periodontal disease. It has been documented that the proportion of (CD14 + CD16+) non-classical monocytes in the blood are elevated in chronic ... ...

    Abstract Monocytes and their macrophage progeny are thought to be involved in tissue and alveolar bone destruction in periodontal disease. It has been documented that the proportion of (CD14 + CD16+) non-classical monocytes in the blood are elevated in chronic periodontitis;A total of 20 chronic generalized periodontitis patients who were otherwise healthy, were recruited for this study. At baseline and 3 weeks after non-surgical periodontal treatment, peripheral blood was obtained to assess the levels of C-reactive protein (CRP) and the proportion of monocyte subsets. Monocyte subsets were assessed using flow cytometry;The mean percentage of CD14 + CD16+ non-classical monocytes in the peripheral blood sample at baseline was 13.95 + 2.09, that reduced to 8.94 + 1.23 3 weeks after non-surgical treatment. A distinct significant reduction in the percentage of non-classical monocytes and a concomitant increase in classical monocytes were observed following periodontal treatment compared to baseline. There was a significant reduction in the all the periodontal parameters and CRP levels 3 weeks post non-surgical periodontal treatment. A positive correlation between CRP and percentage of non-classical monocytes was also observed; Periodontal treatment potentially modulates the host response effectively.
    MeSH term(s) Humans ; Monocytes/metabolism ; Receptors, IgG/metabolism ; Lipopolysaccharide Receptors/metabolism ; Macrophages ; Chronic Periodontitis/therapy ; Chronic Periodontitis/metabolism
    Chemical Substances Receptors, IgG ; Lipopolysaccharide Receptors
    Language English
    Publishing date 2024-01-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 2091511-1
    ISSN 1472-6831 ; 1472-6831
    ISSN (online) 1472-6831
    ISSN 1472-6831
    DOI 10.1186/s12903-023-03793-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Anticancer Effects of

    Varadarajan, Saranya / Madapusi, Balaji Thodur / Narasimhan, Malathi / Pandian, Chamundeeswari Durai / Dhanapal, Sakthisekaran

    The journal of contemporary dental practice

    2022  Volume 23, Issue 8, Page(s) 839–844

    Abstract: Aim: The study aimed to assess the anticancer effects of leaves of the male and female plant and seeds : Materials and methods: Extracts of CO: Results: The ethanol:water extract of : Conclusion: C. papaya: Clinical significance: The ... ...

    Abstract Aim: The study aimed to assess the anticancer effects of leaves of the male and female plant and seeds
    Materials and methods: Extracts of CO
    Results: The ethanol:water extract of
    Conclusion: C. papaya
    Clinical significance: The anticancer effects of papaya leaves and seeds could be further explored to develop an adjunct therapy for oral cancer to improve prognosis and reduce recurrence rates.
    MeSH term(s) Humans ; Carica ; Plant Extracts/pharmacology ; Carcinoma, Squamous Cell/drug therapy ; Squamous Cell Carcinoma of Head and Neck ; Mouth Neoplasms/drug therapy ; Antineoplastic Agents/pharmacology ; Cell Line ; Plant Leaves ; Head and Neck Neoplasms
    Chemical Substances benzyl isothiocyanate (871J6YOR8Q) ; Plant Extracts ; Antineoplastic Agents
    Language English
    Publishing date 2022-08-01
    Publishing country India
    Document type Journal Article
    ISSN 1526-3711
    ISSN (online) 1526-3711
    DOI 10.5005/jp-journals-10024-3384
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The SARS-CoV-2 Virus could Downregulate Dual Specificity Phosphatase-1 Expression in Oral Cancer: A Plausible Hypothesis that could Explain Oral Cancer Progression in the COVID-19 Pandemic and Post-pandemic Situation.

    Ramesh, Rajeswari / Siroraj, Pearlcid / Varadarajan, Saranya / Balaji, Thodur Madapusi / Patil, Shankargouda

    The journal of contemporary dental practice

    2022  Volume 23, Issue 10, Page(s) 963–964

    Abstract: This study explores the downregulation of Dual Specificity Phosphatase-1 (DUSP-1) expression in oral cancer progression during the pandemic and post-pandemic situations. Keywords: COVID-19, Dual specificity phosphatase-1, Oral cancer, SARS-CoV-2. ...

    Abstract This study explores the downregulation of Dual Specificity Phosphatase-1 (DUSP-1) expression in oral cancer progression during the pandemic and post-pandemic situations. Keywords: COVID-19, Dual specificity phosphatase-1, Oral cancer, SARS-CoV-2.
    MeSH term(s) Humans ; COVID-19 ; Mouth Neoplasms/epidemiology ; Neoplastic Processes ; SARS-CoV-2 ; Dual Specificity Phosphatase 1/genetics ; Disease Progression ; Gene Expression Regulation, Neoplastic
    Chemical Substances DUSP1 protein, human (EC 3.1.3.48) ; Dual Specificity Phosphatase 1 (EC 3.1.3.48)
    Language English
    Publishing date 2022-10-01
    Publishing country India
    Document type Editorial
    ISSN 1526-3711
    ISSN (online) 1526-3711
    DOI 10.5005/jp-journals-10024-3334
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Hypothesizing the potential role of melatonin in inhibiting epithelial to mesenchymal transition in oral squamous cell carcinoma.

    Madapusi Balaji, Thodur / Varadarajan, Saranya / Jagannathan, Raghunathan / Raj, A Thirumal / Sridhar, Lakshmi Priya / Patil, Shankaragouda

    Medical hypotheses

    2020  Volume 145, Page(s) 110346

    MeSH term(s) Carcinoma, Squamous Cell/drug therapy ; Cell Line, Tumor ; Epithelial-Mesenchymal Transition ; Humans ; Melatonin ; Mouth Neoplasms/drug therapy ; Squamous Cell Carcinoma of Head and Neck
    Chemical Substances Melatonin (JL5DK93RCL)
    Language English
    Publishing date 2020-10-15
    Publishing country United States
    Document type Letter
    ZDB-ID 193145-3
    ISSN 1532-2777 ; 0306-9877
    ISSN (online) 1532-2777
    ISSN 0306-9877
    DOI 10.1016/j.mehy.2020.110346
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1132: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: The SARS-CoV-2 Virus may Remain Viable on Oral Appliances for up to 3 Days?

    Balaji, Thodur Madapusi / Varadarajan, Saranya / Raj, A Thirumal / Patil, Shankargouda

    The journal of contemporary dental practice

    2020  Volume 21, Issue 6, Page(s) 597

    Abstract: The SARS-CoV-2 virus has created havoc in the world by causing the COVID-19 pandemic. ...

    Abstract The SARS-CoV-2 virus has created havoc in the world by causing the COVID-19 pandemic.
    MeSH term(s) Aged ; Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Humans ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2 ; Severe Acute Respiratory Syndrome/epidemiology
    Keywords covid19
    Language English
    Publishing date 2020-06-01
    Publishing country India
    Document type Journal Article
    ISSN 1526-3711
    ISSN (online) 1526-3711
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Estimation of GCF and Salivary Levels of NT-proBNP in Systemically Healthy Subjects with Severe Chronic Periodontitis Before and After Periodontal Flap Surgery.

    Ari, Geetha / Rajendran, Sathish / Mahendra, Jaideep / Ambalavanan, N / Vijayaraj, Shonali / Mahendra, Little / Madapusi Balaji, Thodur / Ali Baeshen, Hosam / Patil, Shankargouda / Reda, Rodolfo / Testarelli, Luca

    International journal of general medicine

    2023  Volume 16, Page(s) 1809–1816

    Abstract: Purpose: The aim of the study was to estimate and compare the Saliva and GCF levels of NT-proBNP in systemically healthy subjects with severe chronic periodontitis before and after periodontal flap surgery.: Materials and methods: Twenty subjects ... ...

    Abstract Purpose: The aim of the study was to estimate and compare the Saliva and GCF levels of NT-proBNP in systemically healthy subjects with severe chronic periodontitis before and after periodontal flap surgery.
    Materials and methods: Twenty subjects were selected and divided into two groups based on inclusion and exclusion criteria. Healthy Controls: 10 periodontally and systemically healthy subjects. Presurgery Group: 10 systemically healthy subjects with severe chronic generalized periodontitis. Postsurgery Group included Presurgery Group subjects who will undergo periodontal flap surgery. After the periodontal parameters were measured, GCF and saliva samples were collected. Postsurgery Group subjects underwent periodontal flap surgery and both periodontal parameters and GCF and saliva levels were reassessed after 6 months.
    Results: Presurgery Group showed a higher mean value of plaque index, modified gingival index, probing pocket depth and clinical attachment level when compared to Healthy Controls and it was found to decrease after periodontal flap surgery (Postsurgery Group). Intergroup comparison (Presurgery Group vs Postsurgery Group) of the mean difference of salivary NT-proBNP was found to be statistically significant. GCF levels of NT-proBNP also decreased after periodontal flap surgery but the difference was not statistically significant.
    Conclusion: NT pro-BNP levels were found to be higher in periodontitis group as compared to the controls. The levels decreased following surgical periodontal therapy, elucidating the role of periodontal treatment on the expression of NT-proBNP as a salivary and GCF marker. NT-proBNP could serve as a potential biomarker for periodontitis in saliva and GCF in future.
    Language English
    Publishing date 2023-05-15
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2452220-X
    ISSN 1178-7074
    ISSN 1178-7074
    DOI 10.2147/IJGM.S402929
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: COVID-19 pandemic and lock-down protocols: Impact in an indian tertiary cancer center.

    Dillibabu, Theerthika / Varadarajan, Saranya / Balaji, Thodur Madapusi / Balakrishnan, Priyanka / Tangutur, Shashank / Patil, Shankargouda / Raj, A Thirumal

    Oral oncology

    2021  Volume 124, Page(s) 105484

    MeSH term(s) COVID-19/epidemiology ; COVID-19/prevention & control ; Humans ; India/epidemiology ; Pandemics ; Quarantine ; Tertiary Care Centers
    Language English
    Publishing date 2021-08-11
    Publishing country England
    Document type Letter
    ZDB-ID 1120465-5
    ISSN 1879-0593 ; 0964-1955 ; 1368-8375
    ISSN (online) 1879-0593
    ISSN 0964-1955 ; 1368-8375
    DOI 10.1016/j.oraloncology.2021.105484
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4869: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.A 456: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  10. Article ; Online: Assessing the

    Ramamurthy, Shanmugapriya / Thiagarajan, Kavitha / Varghese, Sheeja / Kumar, Rajesh / Karthick, B Prem / Varadarajan, Saranya / Balaji, Thodur Madapusi

    The journal of contemporary dental practice

    2022  Volume 23, Issue 4, Page(s) 437–442

    Abstract: Background: Chronic inflammation and oxidative stress play a vital role in the pathogenesis of various diseases of the oral cavity including periodontal disease. Phytochemicals present in plants with antioxidant (AO) and anti-inflammatory properties ... ...

    Abstract Background: Chronic inflammation and oxidative stress play a vital role in the pathogenesis of various diseases of the oral cavity including periodontal disease. Phytochemicals present in plants with antioxidant (AO) and anti-inflammatory properties could aid as a therapeutic adjunct in the management of these diseases.
    Aim: To assess the antioxidant and anti-inflammatory effects of aqueous and ethanolic extracts of
    Materials and methods: Aqueous and ethanolic extracts of
    Results: Both the test substances exhibited significant antioxidant and anti-inflammatory activity, and aqueous extracts exhibited higher activity than ethanolic extract.
    Summary and conclusion: The anti-inflammatory and antioxidant activity of
    MeSH term(s) Anti-Inflammatory Agents/pharmacology ; Antioxidants/pharmacology ; Humans ; Moringa oleifera/chemistry ; Periodontal Diseases/drug therapy ; Plant Extracts/chemistry ; Plant Extracts/pharmacology ; Plant Leaves/chemistry
    Chemical Substances Anti-Inflammatory Agents ; Antioxidants ; Plant Extracts
    Language English
    Publishing date 2022-04-01
    Publishing country India
    Document type Journal Article
    ISSN 1526-3711
    ISSN (online) 1526-3711
    Database MEDical Literature Analysis and Retrieval System OnLINE

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