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  1. Book ; Online: Mapping the Cyberbiosecurity Enterprise

    Murch, Randall / DiEuliis, Diane

    2019  

    Keywords Civil engineering, surveying & building ; Biotechnology ; cyberbiosecurity ; biosecurity ; cybersecurity ; Biopharma ; Cyber-Biological Infrastructure ; Food and Agriculture Systems ; National and Transnational Security
    Size 1 electronic resource (123 pages)
    Publisher Frontiers Media SA
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021230102
    ISBN 9782889632138 ; 288963213X
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Perspective: The Rapidly Expanding Need for Biosecurity by Design.

    DiEuliis, Diane

    Biodesign research

    2022  Volume 2022, Page(s) 9809058

    Abstract: Advancing biotechnologies are revolutionizing not only health and medicine, but also many different sectors such as agriculture, energy, chemistry, and textiles. As synthetic biology is leveraged as a programmable platform for the creation and biodesign ... ...

    Abstract Advancing biotechnologies are revolutionizing not only health and medicine, but also many different sectors such as agriculture, energy, chemistry, and textiles. As synthetic biology is leveraged as a programmable platform for the creation and biodesign of high-value biological medicines, foods, and commodities, the world is facing new territory in terms of ensuring the safety and security of both novel and engineered biological organisms, as well as the biological and digital platforms in which they are designed. Biosecurity practices and policies have traditionally revolved around preventing the misuse of biological pathogens, primarily through controlling access to pathogens. The advent of biodesign capabilities, such as gene editors, gene synthesis capabilities, and genetic engineering, requires a reevaluation of traditional biosecurity policies to mitigate risks associated with such engineering of biological entities. Here, features of "Biosecurity by Design" approaches are described, including the application of risk/benefit analysis and risk mitigation, post-COVID opportunities, and ethical global norms in the progression of biodesign and growing bioeconomies.
    Language English
    Publishing date 2022-05-25
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2693-1257
    ISSN (online) 2693-1257
    DOI 10.34133/2022/9809058
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Safely balancing a double-edged blade: identifying and mitigating emerging biosecurity risks in precision medicine.

    DiEuliis, Diane / Giordano, James J

    Frontiers in medicine

    2024  Volume 11, Page(s) 1364703

    Abstract: Tools and methods of precision medicine are developing rapidly, through both iterative discoveries enabled by innovations in biomedical research (e.g., genome editing, synthetic biology, bioengineered devices). These are strengthened by advancements in ... ...

    Abstract Tools and methods of precision medicine are developing rapidly, through both iterative discoveries enabled by innovations in biomedical research (e.g., genome editing, synthetic biology, bioengineered devices). These are strengthened by advancements in information technology and the increasing body of data-as assimilated, analyzed, and made accessible-and affectable-through current and emerging cyber-and systems- technologies. Taken together, these approaches afford ever greater volume and availability of individual and collective human data. Machine learning and/or artificial intelligence approaches are broadening this dual use risk; and in the aftermath of COVID-19, there is growing incentive and impetus to gather more biological data from individuals and their environments on a routine basis. By engaging these data-and the interventions that are based upon them, precision medicine offer promise of highly individualized treatments for disease and injury, optimization of structure and function, and concomitantly, the potential for (mis) using data to incur harm. This double-edged blade of benefit and risk obligates the need to safeguard human data from purloinment, through systems, guidelines and policies of a novel discipline, cyberbiosecurity, which, as coupled to ethical precepts, aims to protect human privacy, agency, and safety in ways that remain apace with scientific and technological advances in biomedicine. Herein, current capabilities and trajectories precision medicine are described as relevant to their dual use potential, and approaches to biodata security (
    Language English
    Publishing date 2024-03-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2024.1364703
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: The Need for Modernization of Biosecurity in the Post-COVID World.

    DiEuliis, Diane / Giordano, James

    mSphere

    2022  Volume 7, Issue 2, Page(s) e0002522

    Abstract: At present, there are two hypotheses about the emergence of SARS-CoV-2; the first is that it was due to a naturally occurring zoonotic jump, and the second contends that it spread due to an accidental dispersion of a laboratory-acquired infection in ... ...

    Abstract At present, there are two hypotheses about the emergence of SARS-CoV-2; the first is that it was due to a naturally occurring zoonotic jump, and the second contends that it spread due to an accidental dispersion of a laboratory-acquired infection in Wuhan, China. While the pandemic's actual origins remain occluded, it is useful to examine the latter possibility as a paradigm for evaluating biosecurity policy in the post-COVID world. While the pandemic may not have emerged from a research lab, this is possible with research on dangerous pathogens and prompts questions for biosecurity. How might biosecurity protections for such research be modernized while still enabling important, necessary public health research that utilizes dual-use or gain-of-function capabilities? As the world takes urgent action to mitigate shortcomings in the response to COVID-19, such questions and their potential solutions are vital to inform and direct future life science and technology endeavors.
    MeSH term(s) Biosecurity ; COVID-19 ; Humans ; Pandemics/prevention & control ; Public Health ; SARS-CoV-2
    Language English
    Publishing date 2022-02-28
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ISSN 2379-5042
    ISSN (online) 2379-5042
    DOI 10.1128/msphere.00025-22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Balancing Act: Precision Medicine and National Security.

    DiEuliis, Diane / Giordano, James

    Military medicine

    2022  Volume 187, Issue Suppl 1, Page(s) 32–35

    Abstract: Developments in genetics, pharmacology, biomarker identification, imaging, and interventional biotechnology are enabling medicine to become increasingly more precise in "personalized" approaches to assessing and treating individual patients. Here we ... ...

    Abstract Developments in genetics, pharmacology, biomarker identification, imaging, and interventional biotechnology are enabling medicine to become increasingly more precise in "personalized" approaches to assessing and treating individual patients. Here we describe current scientific and technological developments in precision medicine and elucidate the dual-use risks of employing these tools and capabilities to exert disruptive influence upon human health, economics, social structure, military capabilities, and global dimensions of power. We advocate continued enterprise toward more completely addressing nuances in the ethical systems and approaches that can-and should-be implemented (and communicated) to more effectively inform policy to guide and govern the biosecurity and use of current and emerging bioscience and technology on the rapidly shifting global stage.
    MeSH term(s) Biotechnology ; Humans ; Policy ; Precision Medicine/methods ; Security Measures
    Language English
    Publishing date 2022-01-25
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 391061-1
    ISSN 1930-613X ; 0026-4075
    ISSN (online) 1930-613X
    ISSN 0026-4075
    DOI 10.1093/milmed/usab017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Un I Zs.546: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: The Shield and Sword of Biosecurity: Balancing the Ethics of Public Safety and Global Preparedness.

    DiEuliis, Diane / Giordano, James

    The American journal of bioethics : AJOB

    2020  Volume 20, Issue 7, Page(s) 142–144

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Global Health ; Humans ; International Cooperation ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-07-27
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2060433-6
    ISSN 1536-0075 ; 1526-5161
    ISSN (online) 1536-0075
    ISSN 1526-5161
    DOI 10.1080/15265161.2020.1779859
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6814: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  7. Article: Editorial: Mapping the Cyberbiosecurity Enterprise.

    Murch, Randall / DiEuliis, Diane

    Frontiers in bioengineering and biotechnology

    2019  Volume 7, Page(s) 235

    Language English
    Publishing date 2019-10-03
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2719493-0
    ISSN 2296-4185
    ISSN 2296-4185
    DOI 10.3389/fbioe.2019.00235
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Mapping the Synthetic Biology Industry: Implications for Biosecurity.

    Carter, Sarah / DiEuliis, Diane

    Health security

    2019  Volume 17, Issue 5, Page(s) 403–406

    MeSH term(s) Biotechnology/trends ; Government Regulation ; Humans ; Industry/trends ; Interviews as Topic ; Security Measures/standards ; Stakeholder Participation ; Synthetic Biology ; United States ; United States Dept. of Health and Human Services
    Language English
    Publishing date 2019-10-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2823049-8
    ISSN 2326-5108 ; 2326-5094
    ISSN (online) 2326-5108
    ISSN 2326-5094
    DOI 10.1089/hs.2019.0078
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Breaching the Department of Defense's Biotech Bottleneck.

    DiEuliis, Diane / Terrell, Patrick / Emanuel, Peter

    Health security

    2020  Volume 18, Issue 2, Page(s) 139–144

    Abstract: The global biotechnology revolution offers a profusion of promising innovations for the US Department of Defense (DoD). As with other emerging technologies, the commercial market, rather than defense, is driving the evolution of biotechnology products, ... ...

    Abstract The global biotechnology revolution offers a profusion of promising innovations for the US Department of Defense (DoD). As with other emerging technologies, the commercial market, rather than defense, is driving the evolution of biotechnology products, and the ability to harness biotechnology for defense benefits has been hampered by strategic confusion in DoD. Here we describe a set of high-level challenges and a set of potential solutions that could bring innovative biotechnology closer to reality for the warfighter and DoD writ large.
    MeSH term(s) Biotechnology ; Commerce ; United States ; United States Department of Defense/organization & administration ; Warfare
    Language English
    Publishing date 2020-04-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2823049-8
    ISSN 2326-5108 ; 2326-5094
    ISSN (online) 2326-5108
    ISSN 2326-5094
    DOI 10.1089/hs.2019.0150
    Database MEDical Literature Analysis and Retrieval System OnLINE

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