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  1. Article: Acceptance remarks of Joseph L Goldstein and Michael S. Brown on the occasion of the presentation of the Kober Medal, 2002.

    Goldstein, Joseph L / Brown, Michael S

    The Journal of clinical investigation

    2002  Volume 110, Issue 12, Page(s) S11–3

    MeSH term(s) Animals ; Awards and Prizes ; Biomedical Research ; Cholesterol/metabolism ; Education, Medical ; Humans ; Societies, Scientific ; United States
    Chemical Substances Cholesterol (97C5T2UQ7J)
    Language English
    Publishing date 2002-12-19
    Publishing country United States
    Document type Address
    ZDB-ID 3067-3
    ISSN 1558-8238 ; 0021-9738
    ISSN (online) 1558-8238
    ISSN 0021-9738
    DOI 10.1172/jci120038
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Michael S. Brown, MD and Joseph L. Goldstein, MD. 1985 Nobel laureates in medicine.

    Brown, M S / Goldstein, J L

    Journal of investigative medicine : the official publication of the American Federation for Clinical Research

    1996  Volume 44, Issue 2, Page(s) 14–23

    Abstract: When Michael S. Brown, MD and Joseph L. Goldstein, MD first met as interns at the Massachusetts ... with myocardial infarction, Brown and Goldstein, who relocated to the University of Texas Southwestern Medical Center in 1972 ... the Nobel Prize in Medicine in 1985. Today, as Regental Professors of the University of Texas, Brown and Goldstein ...

    Abstract When Michael S. Brown, MD and Joseph L. Goldstein, MD first met as interns at the Massachusetts General Hospital in 1966, they could hardly have imagined that their careers would continue to be intertwined some 30 years later. It was shortly following their arrival as clinical associates at the National Institutes of Health in 1968 that the pair developed an interest in abnormalities of cholesterol metabolism. Bolstered by epidemiologic data that showed elevated cholesterol levels in many patients with myocardial infarction, Brown and Goldstein, who relocated to the University of Texas Southwestern Medical Center in 1972, began a search for receptors important in cholesterol homeostasis. These studies, performed in their early stages while juggling clinical duties at Parkland Hospital, culminated in a series of scientific achievements which merited among other honors the Hazen Award in 1982, the Lasker Award in 1985, and the Nobel Prize in Medicine in 1985. Today, as Regental Professors of the University of Texas, Brown and Goldstein head a laboratory group which continues to test the cutting edge of medical research. Although impressed with the pace of technological advances in biology, the declining role of clinically oriented physicians in biomedical research troubles the pair. Interviewed in their library in Dallas, Brown and Goldstein spoke about the complicated balance of science, medicine, and education necessary to produce another generation of successful investigators.
    MeSH term(s) Cholesterol/metabolism ; Education, Medical ; Homeostasis ; Humans ; Nobel Prize ; Research Support as Topic ; Science
    Chemical Substances Cholesterol (97C5T2UQ7J)
    Language English
    Publishing date 1996-02
    Publishing country England
    Document type Interview
    ZDB-ID 1217870-6
    ISSN 1708-8267 ; 1081-5589 ; 0009-9279
    ISSN (online) 1708-8267
    ISSN 1081-5589 ; 0009-9279
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Online: The Current State of the Art in Pediatric Acute Kidney Injury

    Goldstein, Stuart L. / Joseph Askenazi, David / Joseph Askenazi, David

    2020  

    Keywords Medicine ; Paediatric medicine ; acute kidney injury ; children ; biomarkers ; risk stratification ; renal replacement therapy
    Size 1 electronic resource (59 pages)
    Publisher Frontiers Media SA
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021230387
    ISBN 9782889639526 ; 2889639525
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Article ; Online: The secret to a successful career in science-according to Magritte.

    Goldstein, Joseph L

    Proceedings of the National Academy of Sciences of the United States of America

    2023  Volume 120, Issue 39, Page(s) e2304819120

    Language English
    Publishing date 2023-09-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 209104-5
    ISSN 1091-6490 ; 0027-8424
    ISSN (online) 1091-6490
    ISSN 0027-8424
    DOI 10.1073/pnas.2304819120
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  5. Article ; Online: How the JCI's most-cited paper sparked the field of lipoprotein research.

    Brown, Michael S / Goldstein, Joseph L

    The Journal of clinical investigation

    2024  Volume 134, Issue 4

    Language English
    Publishing date 2024-02-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3067-3
    ISSN 1558-8238 ; 0021-9738
    ISSN (online) 1558-8238
    ISSN 0021-9738
    DOI 10.1172/JCI177475
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  6. Article ; Online: The art and science of building castles in the sky and houses of cards that don't collapse.

    Goldstein, Joseph L

    Cell

    2022  Volume 185, Issue 21, Page(s) 3839–3843

    Abstract: The creative process in art and science involves two phases-generating and exploring new and wild ideas (building castles in the sky) and then narrowing down and focusing on the most tractable and useful ones (building houses of cards that don't topple ... ...

    Abstract The creative process in art and science involves two phases-generating and exploring new and wild ideas (building castles in the sky) and then narrowing down and focusing on the most tractable and useful ones (building houses of cards that don't topple over).
    MeSH term(s) Art ; Awards and Prizes ; Creativity ; Humans ; Science
    Language English
    Publishing date 2022-09-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 187009-9
    ISSN 1097-4172 ; 0092-8674
    ISSN (online) 1097-4172
    ISSN 0092-8674
    DOI 10.1016/j.cell.2022.08.027
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  7. Article ; Online: The surprise element: A hallmark of creativity in scientists, artists, and comedians.

    Goldstein, Joseph L

    Cell

    2021  Volume 184, Issue 21, Page(s) 5261–5265

    Abstract: Truly creative works of science and art produce unexpected and surprising results-just like the punch line of a good joke that generates an unfamiliar twist on a familiar idea. Surprise stimulates curiosity, which triggers a search to reveal the mystery ... ...

    Abstract Truly creative works of science and art produce unexpected and surprising results-just like the punch line of a good joke that generates an unfamiliar twist on a familiar idea. Surprise stimulates curiosity, which triggers a search to reveal the mystery of things unknown.
    MeSH term(s) Art ; Awards and Prizes ; Creativity ; Humans ; Paintings ; Science ; Sculpture ; Wit and Humor as Topic
    Language English
    Publishing date 2021-09-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 187009-9
    ISSN 1097-4172 ; 0092-8674
    ISSN (online) 1097-4172
    ISSN 0092-8674
    DOI 10.1016/j.cell.2021.08.007
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  8. Article ; Online: Toppling the Tower of Babel: Large Language Models in Academia.

    Tsai, Mitchell H / Goldstein, Joseph C / Goldstein, Heide V / Wang, Zuyue / Dauerman, Harold L

    Journal of clinical anesthesia

    2024  Volume 96, Page(s) 111462

    Language English
    Publishing date 2024-04-27
    Publishing country United States
    Document type Letter
    ZDB-ID 1011618-7
    ISSN 1873-4529 ; 0952-8180
    ISSN (online) 1873-4529
    ISSN 0952-8180
    DOI 10.1016/j.jclinane.2024.111462
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  9. Article ; Online: The 2020 Lasker Awards and the COVID-19 Pandemic.

    Goldstein, Joseph L

    JAMA

    2020  Volume 324, Issue 15, Page(s) 1497–1498

    MeSH term(s) Awards and Prizes ; Biomedical Research ; COVID-19 ; History, 20th Century ; History, 21st Century ; Humans ; Infectious Disease Medicine/history ; Nobel Prize
    Keywords covid19
    Language English
    Publishing date 2020-09-25
    Publishing country United States
    Document type Historical Article ; Journal Article
    ZDB-ID 2958-0
    ISSN 1538-3598 ; 0254-9077 ; 0002-9955 ; 0098-7484
    ISSN (online) 1538-3598
    ISSN 0254-9077 ; 0002-9955 ; 0098-7484
    DOI 10.1001/jama.2020.17056
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  10. Article ; Online: The Spanish 1918 Flu and the COVID-19 Disease: The Art of Remembering and Foreshadowing Pandemics.

    Goldstein, Joseph L

    Cell

    2020  Volume 183, Issue 2, Page(s) 285–289

    Abstract: Tragic events such as pandemics can be remembered as well as foreshadowed by works of art. Paintings by the artists Edvard Munch and John Singer Sargent (1918-19) tell us in real time what it was like to be stricken by the Spanish flu. Paintings by ... ...

    Abstract Tragic events such as pandemics can be remembered as well as foreshadowed by works of art. Paintings by the artists Edvard Munch and John Singer Sargent (1918-19) tell us in real time what it was like to be stricken by the Spanish flu. Paintings by Edward Hopper (1940s and '50s) foretell the lockdown and social distancing of today's COVID-19 pandemic.
    MeSH term(s) COVID-19 ; Coronavirus Infections/epidemiology ; Disease Outbreaks ; Famous Persons ; History, 20th Century ; Humans ; Influenza Pandemic, 1918-1919 ; Influenza, Human/epidemiology ; Medicine in the Arts ; Pandemics ; Pneumonia, Viral/epidemiology ; World War I
    Keywords covid19
    Language English
    Publishing date 2020-11-24
    Publishing country United States
    Document type Historical Article ; Journal Article
    ZDB-ID 187009-9
    ISSN 1097-4172 ; 0092-8674
    ISSN (online) 1097-4172
    ISSN 0092-8674
    DOI 10.1016/j.cell.2020.09.030
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