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  1. Article ; Online: Authors' Response to Ashton Gatewood and Michael Harding: Tribal Partnerships as an Avenue Forward.

    Green, Larry A / Miller, William L / Frey, John J / Jason, Hilliard / Westberg, Jane / Cohen, Deborah J / Gotler, Robin S / DeGruy, Frank V

    Family medicine

    2022  Volume 54, Issue 5, Page(s) 405–406

    MeSH term(s) Cooperative Behavior ; Humans ; Indians, North American
    Language English
    Publishing date 2022-05-10
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 639374-3
    ISSN 1938-3800 ; 0742-3225
    ISSN (online) 1938-3800
    ISSN 0742-3225
    DOI 10.22454/FamMed.2022.364987
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Reply: The pelvic floor is a function of the body continuum.

    DeLancey, John O / Mastrovito, Sara / Ashton-Miller, James A

    American journal of obstetrics and gynecology

    2024  

    Language English
    Publishing date 2024-02-15
    Publishing country United States
    Document type Letter
    ZDB-ID 80016-8
    ISSN 1097-6868 ; 0002-9378
    ISSN (online) 1097-6868
    ISSN 0002-9378
    DOI 10.1016/j.ajog.2024.02.019
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  3. Article ; Online: Letter to the editor: Stress urinary incontinence is caused predominantly by urethral support failure.

    DeLancey, John O / Ashton-Miller, James A

    International urogynecology journal

    2022  Volume 33, Issue 5, Page(s) 1357–1358

    MeSH term(s) Humans ; Urethra ; Urinary Incontinence, Stress/etiology ; Urinary Incontinence, Stress/therapy ; Urodynamics
    Language English
    Publishing date 2022-03-17
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 1050631-7
    ISSN 1433-3023 ; 0937-3462
    ISSN (online) 1433-3023
    ISSN 0937-3462
    DOI 10.1007/s00192-022-05162-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Levels of ACL-straining activities increased in the six months prior to non-contact ACL injury in a retrospective survey: evidence consistent with ACL fatigue failure.

    Grodman, Louis H / Beaulieu, Mélanie L / Ashton-Miller, James A / Wojtys, Edward M

    Frontiers in physiology

    2023  Volume 14, Page(s) 1166980

    Abstract: Introduction: ...

    Abstract Introduction:
    Language English
    Publishing date 2023-05-05
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564217-0
    ISSN 1664-042X
    ISSN 1664-042X
    DOI 10.3389/fphys.2023.1166980
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  5. Article ; Online: The influence of chair recline and head and neck position on upper trapezius activity and stiffness during seated computer work.

    Wolff, Whitney L / Heinemann, Constantin M / Kartes, Jordan M / Ashton-Miller, James A / Lipps, David B

    Applied ergonomics

    2024  Volume 117, Page(s) 104227

    Abstract: Increasing chair recline during seated computer work may reduce the load placed on the upper trapezius (UT), a common location of pain for those with idiopathic chronic neck pain. This study determined the effect of increasing chair recline on UT ... ...

    Abstract Increasing chair recline during seated computer work may reduce the load placed on the upper trapezius (UT), a common location of pain for those with idiopathic chronic neck pain. This study determined the effect of increasing chair recline on UT stiffness and muscle activity during computer work in people with and without idiopathic chronic neck pain. Surface electromyography and ultrasound shear wave elastography were collected from three subdivisions of the UT in 15 individuals with idiopathic chronic neck pain and 15 sex-matched healthy controls. Participants sat in a standardized computer-work setup while chair recline (0°, 25°, 45°) and head and neck position (self-selected, neutral, flexed) were systematically adjusted and maintained for 2.5-min intervals. Repeated-measures ANOVAs were completed for each sex, muscle, and data type, with group (chronic neck pain, control), chair recline (0°,25°,45°), head and neck position (self-selected, flexed, neutral), and side of collected data (dominant, non-dominant) as fixed factors. Men with idiopathic chronic neck pain demonstrated greater UT stiffness in the cranial subdivision when compared to healthy men. Additionally, the 25° and 45° recline levels increased the stiffness of men's dominant UT compared to men's non-dominant UT. Women's UT was more affected by head and neck position, and a neutral head and neck position resulted in lower UT activation, but higher UT stiffness for the cranial subdivision and midway between C-7 and the acromion process. Overall, our findings suggest that the commonly suggested neutral position may not be a beneficial prompt when positioning someone during seated computer work.
    MeSH term(s) Male ; Humans ; Female ; Neck Pain ; Superficial Back Muscles ; Sitting Position ; Head ; Electromyography/methods ; Neck Muscles/physiology
    Language English
    Publishing date 2024-01-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 2003513-5
    ISSN 1872-9126 ; 0003-6870
    ISSN (online) 1872-9126
    ISSN 0003-6870
    DOI 10.1016/j.apergo.2024.104227
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  6. Article ; Online: Functional Anatomy of Urogenital Hiatus Closure: the Perineal Complex Triad Hypothesis.

    DeLancey, John O / Pipitone, Fernanda / Masteling, Mariana / Xie, Bing / Ashton-Miller, James A / Chen, Luyun

    International urogynecology journal

    2024  Volume 35, Issue 2, Page(s) 441–449

    Abstract: Introduction: Urogenital hiatus enlargement is a critical factor associated with prolapse and operative failure. This study of the perineal complex was performed to understand how interactions among its three structures: the levator ani, perineal ... ...

    Abstract Introduction: Urogenital hiatus enlargement is a critical factor associated with prolapse and operative failure. This study of the perineal complex was performed to understand how interactions among its three structures: the levator ani, perineal membrane, and perineal body-united by the vaginal fascia-work to maintain urogenital hiatus closure.
    Methods: Magnetic resonance images from 30 healthy nulliparous women with 3D reconstruction of selected subjects were used to establish overall geometry. Connection points and lines of action were based on perineal dissection in 10 female cadavers (aged 22-86 years), cross sections of 4 female cadavers (aged 14-35 years), and histological sections (cadavers aged 16 and 21 years).
    Results: The perineal membrane originates laterally from the ventral two thirds of the ischiopubic rami and attaches medially to the perineal body and vaginal wall. The levator ani attaches to the perineal membrane's cranial surface, vaginal fascia, and the perineal body. The levator line of action in 3D reconstruction is oriented so that the levator pulls the medial perineal membrane cranio-ventrally. In cadavers, simulated levator contraction and relaxation along this vector changes the length of the membrane and the antero-posterior diameter of the urogenital hiatus. Loss of the connection of the left and right perineal membranes through the perineal body results in diastasis of the levator and a widened hiatus, as well as a downward rotation of the perineal membrane.
    Conclusion: Interconnections involving the levator ani muscles, perineal membrane, perineal body, and vaginal fascia form the perineal complex surrounding the urogenital hiatus in an arrangement that maintains hiatal closure.
    MeSH term(s) Female ; Humans ; Perineum ; Pelvic Floor ; Fascia ; Cadaver ; Hypertrophy
    Language English
    Publishing date 2024-01-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 1050631-7
    ISSN 1433-3023 ; 0937-3462
    ISSN (online) 1433-3023
    ISSN 0937-3462
    DOI 10.1007/s00192-023-05708-w
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  7. Article ; Online: Pelvic floor injury during vaginal birth is life-altering and preventable: what can we do about it?

    DeLancey, John O L / Masteling, Mariana / Pipitone, Fernanda / LaCross, Jennifer / Mastrovito, Sara / Ashton-Miller, James A

    American journal of obstetrics and gynecology

    2024  Volume 230, Issue 3, Page(s) 279–294.e2

    Abstract: Pelvic floor disorders after childbirth have distressing lifelong consequences for women, requiring more than 300,000 women to have surgery annually. This represents approximately 10% of the 3 million women who give birth vaginally each year. Vaginal ... ...

    Abstract Pelvic floor disorders after childbirth have distressing lifelong consequences for women, requiring more than 300,000 women to have surgery annually. This represents approximately 10% of the 3 million women who give birth vaginally each year. Vaginal birth is the largest modifiable risk factor for prolapse, the pelvic floor disorder most strongly associated with birth, and is an important contributor to stress incontinence. These disorders require 10 times as many operations as anal sphincter injuries. Imaging shows that injuries of the levator ani muscle, perineal body, and membrane occur in up to 19% of primiparous women. During birth, the levator muscle and birth canal tissues must stretch to more than 3 times their original length; it is this overstretching that is responsible for the muscle tear visible on imaging rather than compression or neuropathy. The injury is present in 55% of women with prolapse later in life, with an odds ratio of 7.3, compared with women with normal support. In addition, levator damage can affect other aspects of hiatal closure, such as the perineal body and membrane. These injuries are associated with an enlarged urogenital hiatus, now known as antedate prolapse, and with prolapse surgery failure. Risk factors for levator injury are multifactorial and include forceps delivery, occiput posterior birth, older maternal age, long second stage of labor, and birthweight of >4000 g. Delivery with a vacuum device is associated with reduced levator damage. Other steps that might logically reduce injuries include manual rotation from occiput posterior to occiput anterior, slow gradual delivery, perineal massage or compresses, and early induction of labor, but these require study to document protection. In addition, teaching women to avoid pushing against a contracted levator muscle would likely decrease injury risk by decreasing tension on the vulnerable muscle origin. Providing care for women who have experienced difficult deliveries can be enhanced with early recognition, physical therapy, and attention to recovery. It is only right that women be made aware of these risks during pregnancy. Educating women on the long-term pelvic floor sequelae of childbirth should be performed antenatally so that they can be empowered to make informed decisions about management decisions during labor.
    MeSH term(s) Pregnancy ; Female ; Humans ; Pelvic Floor/injuries ; Delivery, Obstetric/adverse effects ; Anal Canal/injuries ; Pelvic Floor Disorders/etiology ; Pelvic Floor Disorders/prevention & control ; Prolapse
    Language English
    Publishing date 2024-01-02
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 80016-8
    ISSN 1097-6868 ; 0002-9378
    ISSN (online) 1097-6868
    ISSN 0002-9378
    DOI 10.1016/j.ajog.2023.11.1253
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  8. Article ; Online: Predicting Leg Forces and Knee Moments Using Inertial Measurement Units: An In Vitro Study.

    Ajdaroski, Mirel / Baek, So Young / Ashton-Miller, James A / Esquivel, Amanda O

    Journal of biomechanical engineering

    2023  Volume 146, Issue 2

    Abstract: We compared the ability of seven machine learning algorithms to use wearable inertial measurement unit (IMU) data to identify the severe knee loading cycles known to induce microdamage associated with anterior cruciate ligament rupture. Sixteen cadaveric ...

    Abstract We compared the ability of seven machine learning algorithms to use wearable inertial measurement unit (IMU) data to identify the severe knee loading cycles known to induce microdamage associated with anterior cruciate ligament rupture. Sixteen cadaveric knee specimens, dissected free of skin and muscle, were mounted in a rig simulating standardized jump landings. One IMU was located above and the other below the knee, the applied three-dimensional action and reaction loads were measured via six-axis load cells, and the three-dimensional knee kinematics were also recorded by a laboratory motion capture system. Machine learning algorithms were used to predict the knee moments and the tibial and femur vertical forces; 13 knees were utilized for training each model, while three were used for testing its accuracy (i.e., normalized root-mean-square error) and reliability (Bland-Altman limits of agreement). The results showed the models predicted force and knee moment values with acceptable levels of error and, although several models exhibited some form of bias, acceptable reliability. Further research will be needed to determine whether these types of models can be modified to attenuate the inevitable in vivo soft tissue motion artifact associated with highly dynamic activities like jump landings.
    MeSH term(s) Humans ; Anterior Cruciate Ligament/physiology ; Leg ; Reproducibility of Results ; Knee Joint/physiology ; Anterior Cruciate Ligament Injuries ; Biomechanical Phenomena ; Rotation ; Cadaver
    Language English
    Publishing date 2023-11-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 243094-0
    ISSN 1528-8951 ; 0148-0731
    ISSN (online) 1528-8951
    ISSN 0148-0731
    DOI 10.1115/1.4064145
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  9. Article ; Online: Learning From Failure.

    Ashton-Miller, James A / Zernicke, Ronald F

    Journal of applied biomechanics

    2019  Volume 36, Issue 1, Page(s) 1–3

    Language English
    Publishing date 2019-11-21
    Publishing country United States
    Document type Editorial
    ZDB-ID 1145288-2
    ISSN 1543-2688 ; 1065-8483
    ISSN (online) 1543-2688
    ISSN 1065-8483
    DOI 10.1123/jab.2019-0353
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  10. Article: Relationship Between Lateral Tibial Posterior Slope and Tibiofemoral Kinematics During Simulated Jump Landings in Male Cadaveric Knees.

    Baek, So Young / Beaulieu, Mélanie L / Wojtys, Edward M / Ashton-Miller, James A

    Orthopaedic journal of sports medicine

    2023  Volume 11, Issue 6, Page(s) 23259671231160213

    Abstract: Background: It is not known mechanistically whether a steeper lateral posterior tibial slope (LTS) leads to an increase in anterior tibial translation (ATT) as well as internal tibial rotation (ITR) during a given jump landing.: Hypothesis: A steeper ...

    Abstract Background: It is not known mechanistically whether a steeper lateral posterior tibial slope (LTS) leads to an increase in anterior tibial translation (ATT) as well as internal tibial rotation (ITR) during a given jump landing.
    Hypothesis: A steeper LTS will result in increased ATT and ITR during simulated jump landings when applying knee compression, flexion, and internal tibial torque of increasing severity.
    Study design: Descriptive laboratory study.
    Methods: Seven pairs of cadaveric knees were harvested from young male adult donors (mean ± SD; age, 25.71 ± 5.53 years; weight, 71.51 ± 4.81 kg). The LTS of each knee was measured by a blinded observer from 3-T magnetic resonance images. Two sets of 25 impact trials of ∼700 N (1× body weight [BW] ±10%) followed by 2 sets of 25 trials of 1400 N (2× BW ±10%) were applied to a randomly selected knee of each pair. Similarly, on the contralateral knee, 2 sets of 25 impact trials of ∼1800 N (2.5× BW ±10%) followed by 2 sets of 25 trials of ∼2100 N (3× BW ±10%) were applied. Three-dimensional knee kinematics, including ATT and ITR, were measured at 400 Hz using optoelectronic motion capture. Two-factor linear mixed effect models were used to determine the relationship of LTS to ATT and ITR as impact loading increased.
    Results: As LTS increased, so did ATT and ITR during increasingly severe landings. LTS had an increasing effect on ATT (coefficient, 0.50; 95% CI, 0.29-0.71) relative to impact force (coefficient, 0.52; 95% CI, 0.50-0.53). ITR was proportional to LTS (coefficient, 1.36; 95% CI, 0.80-1.93) under increasing impact force (coefficient, 0.49; 95% CI, 0.47-0.52). For steeper LTS, the increase in ITR was proportionally greater than the increase in ATT.
    Conclusion: In male knee specimens, a steeper LTS significantly increased ATT and ITR during jump landings.
    Clinical relevance: Increases in ITR and ATT during jump landings lead to increased strain on the anterior cruciate ligament and are therefore associated with greater risk of ligament failure.
    Language English
    Publishing date 2023-06-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2706251-X
    ISSN 2325-9671
    ISSN 2325-9671
    DOI 10.1177/23259671231160213
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