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  1. Article ; Online: Nasogastric tube after laparoscopic Heller-Dor surgery: Do you really need it?

    Palomba, Giuseppe / Basile, Raffaele / Capuano, Marianna / Pesce, Marcella / Rurgo, Sara / Sarnelli, Giovanni / De Palma, Giovanni Domenico / Aprea, Giovanni

    Current problems in surgery

    2024  Volume 61, Issue 4, Page(s) 101457

    MeSH term(s) Humans ; Laparoscopy/adverse effects ; Fundoplication ; Treatment Outcome ; Esophageal Achalasia
    Language English
    Publishing date 2024-02-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 753169-2
    ISSN 1535-6337 ; 0011-3840
    ISSN (online) 1535-6337
    ISSN 0011-3840
    DOI 10.1016/j.cpsurg.2024.101457
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Subjective Dry Eye Symptoms and Objective Ocular Surface Signs in a Civil Air Crew Population: A Cross-Sectional Study.

    Fachinetti, Anna / Marelli, Edoardo / Velati, Paola / Minoretti, Piercarlo / De Palma, Giuseppe / Sigurtà, Camilla

    Cureus

    2024  Volume 16, Issue 1, Page(s) e51447

    Abstract: Background Aviation professionals are often exposed to conditions such as low cabin air pressure, reduced humidity, and prolonged artificial lighting, which may predispose them to dry eye disease (DED). We therefore designed a cross-sectional study with ... ...

    Abstract Background Aviation professionals are often exposed to conditions such as low cabin air pressure, reduced humidity, and prolonged artificial lighting, which may predispose them to dry eye disease (DED). We therefore designed a cross-sectional study with three primary objectives. Our first aim was to determine the prevalence of subjective dry eye symptoms among civil flight personnel. To achieve this, we administered the Standard Patient Evaluation of Eye Dryness (SPEED) questionnaire. Second, we performed ocular examinations to assess objective DED indicators, such as the Schirmer's-1 (SCH-1) test and tear film break-up time (TBUT). We then correlated the results of these objective tests with the subjective symptoms reported by the participants. Last, we aimed to identify the independent risk factors for positive SCH-1 and TBUT results among aircrew personnel who did not report subjective dry eye symptoms. Methods The study sample consisted of 189 aircrew personnel (94 men and 95 women; mean age: 35.8 ± 10.4 years). They completed the SPEED questionnaire, a tool for assessing ocular surface symptoms. Participants' symptoms were classified as normal (SPEED scores 0-6), moderate (SPEED scores 7-15), or severe (SPEED scores 16-28). The objective assessment included the SCH-1 test for tear production and the TBUT test for tear film quality. Results A significant majority of participants (n = 165; 87.3%) did not report any subjective symptoms of DED. However, 12.2% (n = 23) and 0.5% (n = 1) of the study subjects experienced moderate and severe symptoms, respectively. The SCH-1 test and TBUT test were positive in 25.4% (n = 48) and 24.9% (n = 47) of the participants, respectively. Interestingly, among the aircrew personnel who did not report any subjective dry eye symptoms (SPEED scores 0-6), 18.8% (n = 31) and 17.6% (n = 29) showed abnormal results on the SCH-1 test and TBUT, respectively. Age was identified as the only independent predictor of a positive TBUT (odds ratio = 1.05, 95% confidence interval (CI) = 1.01-1.08, p = 0.01), with a borderline significant association with a positive SCH-1 test (odds ratio = 1.03, 95% CI = 0.99-1.07, p = 0.06). Conclusions The disparity between subjective symptoms and objective tests emphasizes the significance of incorporating objective measures for screening and diagnosing DED in civil flight personnel. If independently confirmed by future research, our findings could potentially lead to the routine implementation of surveillance protocols that incorporate objective DED indicators. Moreover, as age emerged as an independent predictor of positive results on objective tests, it is crucial to consider age-specific screening strategies.
    Language English
    Publishing date 2024-01-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.51447
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  3. Article ; Online: Spontaneous cancer remission after COVID-19: insights from the pandemic and their relevance for cancer treatment.

    Meo, Concetta / Palma, Giuseppe / Bruzzese, Francesca / Budillon, Alfredo / Napoli, Claudio / de Nigris, Filomena

    Journal of translational medicine

    2023  Volume 21, Issue 1, Page(s) 273

    Abstract: Early in the COVID-19 pandemic, it emerged that the risk of severe outcomes was greater in patients with co-morbidities, including cancer. The huge effort undertaken to fight the pandemic, affects the management of cancer care, influencing their outcome. ...

    Abstract Early in the COVID-19 pandemic, it emerged that the risk of severe outcomes was greater in patients with co-morbidities, including cancer. The huge effort undertaken to fight the pandemic, affects the management of cancer care, influencing their outcome. Despite the high fatality rate of COVID-19 disease in cancer patients, rare cases of temporary or prolonged clinical remission from cancers after SARS-CoV-2 infection have been reported. We have reviewed sixteen case reports of COVID-19 disease with spontaneous cancer reduction of progression. Fourteen cases of remission following viral infections and two after anti-SARS-CoV-2 vaccination. The immune response to COVID-19, may be implicated in both tumor regression, and progression. Specifically, we discuss potential mechanisms which include oncolytic and priming hypotheses, that may have contributed to the cancer regression in these cases and could be useful for future options in cancer treatment.
    MeSH term(s) Humans ; COVID-19 ; Pandemics ; SARS-CoV-2 ; Neoplasms/complications ; Neoplasms/therapy
    Language English
    Publishing date 2023-04-21
    Publishing country England
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2118570-0
    ISSN 1479-5876 ; 1479-5876
    ISSN (online) 1479-5876
    ISSN 1479-5876
    DOI 10.1186/s12967-023-04110-w
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  4. Article: Successful uniportal thoracoscopic removal of a new generation implantable loop recorder accidentally migrated into the left pleural cavity and concomitant re-implantation: A case report.

    Signore, Francesca / Simone, Valentina / Anaclerio, Matteo / Bozza, Nicola / Marulli, Giuseppe / De Palma, Angela

    International journal of surgery case reports

    2023  Volume 105, Page(s) 108012

    Abstract: Introduction: With the spread of the use of implantable loop recorders (ILRs) by cardiologists for outpatient cardiac monitoring, intrathoracic migration represents a rare but possible complication occurring after the placement of these devices. Very ... ...

    Abstract Introduction: With the spread of the use of implantable loop recorders (ILRs) by cardiologists for outpatient cardiac monitoring, intrathoracic migration represents a rare but possible complication occurring after the placement of these devices. Very few cases of ILRs intrathoracic migration into the pleural cavity have been reported, followed in even fewer cases by surgical removal of the devices, but in none re-implantation was performed.
    Presentation of case: We report the first case of a patient with a new generation ILR accidentally migrated into the postero-inferior costophrenic recess of the left pleural cavity, successfully removed by uniportal video-assisted thoracic surgery (VATS) and submitted to re-implantation of a new ILR in the same operating session.
    Discussion: To reduce the risk of ILRs intrathoracic displacement, the insertion technique must be performed in the most suitable part of the chest wall, with the correct incision and angle of penetration, by an expert operator. When migrated into the pleural cavity, surgical removal should be performed to avoid the onset of early and late complications. A mini-invasive surgical approach by uniportal VATS could be considered as the first choice, ensuring a favourable patient outcome. Re-implantation of a new ILR can be safely performed in the same operating session.
    Conclusion: In case of intrathoracic migration of ILRs, early removal by mini-invasive approach is recommended as well as concomitant re-implantation. Beyond periodic monitoring of ILRs by cardiologists, strict radiological follow-up with chest X-ray is advisable after implantation, in order to early identify any abnormalities and correctly manage them.
    Language English
    Publishing date 2023-03-21
    Publishing country Netherlands
    Document type Case Reports
    ISSN 2210-2612
    ISSN 2210-2612
    DOI 10.1016/j.ijscr.2023.108012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Oreoch-1: A Peptide from

    Palma, Francesca / Chianese, Annalisa / Panico, Erica / Greco, Giuseppe / Fusco, Alessandra / Savio, Vittoria / Ruocco, Eleonora / Monti, Alessandra / Doti, Nunzianna / Zannella, Carla / Donnarumma, Giovanna / De Filippis, Anna / Galdiero, Massimiliano

    Pathogens (Basel, Switzerland)

    2023  Volume 12, Issue 10

    Abstract: Staphylococci, ... ...

    Abstract Staphylococci, including
    Language English
    Publishing date 2023-09-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2695572-6
    ISSN 2076-0817
    ISSN 2076-0817
    DOI 10.3390/pathogens12101188
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  6. Article: Prevention is better than cure!

    Lorusso, Mariagrazia / De Palma, Angela / De Iaco, Giulia / Marulli, Giuseppe

    Annals of translational medicine

    2019  Volume 7, Issue 1, Page(s) 25

    Language English
    Publishing date 2019-02-06
    Publishing country China
    Document type Editorial ; Comment
    ZDB-ID 2893931-1
    ISSN 2305-5847 ; 2305-5839
    ISSN (online) 2305-5847
    ISSN 2305-5839
    DOI 10.21037/atm.2018.12.18
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  7. Article: Identification and Assessment of Risks in Biobanking: The Case of the Cancer Institute of Bari.

    De Palma, Giuseppe / Bolondi, Giulia / Tufaro, Antonio / Pelagio, Giuseppe / Brando, Giuseppe / Vitale, Daniela / Paradiso, Angelo Virgilio

    Cancers

    2022  Volume 14, Issue 14

    Abstract: Although research biobanks are among the most promising tools to fight disease and improve public health, there are a range of risks biobanks may face that mainly need to be assessed in an attempt to be relieved. We conducted a strategic insurance review ...

    Abstract Although research biobanks are among the most promising tools to fight disease and improve public health, there are a range of risks biobanks may face that mainly need to be assessed in an attempt to be relieved. We conducted a strategic insurance review of an institutional cancer biobank with the aim of both identifying the insurable risks of our own Biobank and gathering useful evidence of primary exposure to insurable risks. In this practical scenario, risks have been outlined and categorized into inherent and residual risks, along with their possible impact on biobank maintenance. Results at the Biobank of the Cancer Institute of Bari showed evidence of potentially significant and intrinsic risk due to highly relevant threats, along with already implemented improvements that significantly reduce risks to a range of relative acceptability.
    Language English
    Publishing date 2022-07-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers14143460
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  8. Article ; Online: Management strategies and role of telemedicine in a surgery unit during COVID-19 outbreak.

    Palomba, Giuseppe / Dinuzzi, Vincenza Paola / De Palma, Giovanni Domenico / Aprea, Giovanni

    International journal of surgery (London, England)

    2020  Volume 79, Page(s) 189–190

    Keywords covid19
    Language English
    Publishing date 2020-05-30
    Publishing country England
    Document type Letter
    ZDB-ID 2212038-5
    ISSN 1743-9159 ; 1743-9191
    ISSN (online) 1743-9159
    ISSN 1743-9191
    DOI 10.1016/j.ijsu.2020.05.081
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  9. Article ; Online: The use of preoperative three-dimensional reconstruction and intraoperative indocyanine green in laparoscopic adrenalectomy.

    Dinuzzi, Vincenza Paola / Palomba, Giuseppe / De Palma, Giovanni Domenico / Aprea, Giovanni

    International journal of surgery (London, England)

    2020  Volume 81, Page(s) 80–81

    Language English
    Publishing date 2020-07-31
    Publishing country England
    Document type Letter
    ZDB-ID 2212038-5
    ISSN 1743-9159 ; 1743-9191
    ISSN (online) 1743-9159
    ISSN 1743-9191
    DOI 10.1016/j.ijsu.2020.07.040
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  10. Article: A method for the risk assessment of biomechanical overload in hospital physiotherapists.

    Sala, Emma / Bisioli, Andrea / Ponzoni, Pietro / De Bellis, Alessandro / Paraggio, Emilio / De Palma, Giuseppe

    La Medicina del lavoro

    2022  Volume 113, Issue 6, Page(s) e2022057

    Abstract: Background: In physiotherapists, biomechanical overload risk assessment (RA) is particularly complex due to the tasks' variability. The present study aims to propose a new methodology, named Whole Body RA Biomechanical Overload (WB-RAMBO), to assess the ...

    Abstract Background: In physiotherapists, biomechanical overload risk assessment (RA) is particularly complex due to the tasks' variability. The present study aims to propose a new methodology, named Whole Body RA Biomechanical Overload (WB-RAMBO), to assess the risk in the activities performed by physiotherapists.
    Methods: Each type of intervention was broken down into elementary operations. The risk factors (force, repetitiveness, and incongruous postures) were recorded and evaluated for each of these. For each task, the risk level was obtained by integrating the results of multiple ergonomic methods among those proposed by the international literature. To verify and validate the obtained results, we reviewed the medical records of health surveillance carried out on physiotherapists.
    Results: From the ergonomic point of view, RA shows a situation of acceptability. The observed slight dysergonomies are diluted in the work shift and allow an optimal functional recovery of the musculoskeletal system.
    Conclusions: This method proposes a RA for each operation performed. A work plan subjected to such a peculiar RA can be redesigned and adapted to the company's and the hypersusceptible worker's organizational needs.
    MeSH term(s) Humans ; Hospitals ; Risk Assessment
    Language English
    Publishing date 2022-12-07
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 123678-7
    ISSN 0025-7818
    ISSN 0025-7818
    DOI 10.23749/mdl.v113i6.13652
    Database MEDical Literature Analysis and Retrieval System OnLINE

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