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  1. Book: Textbook of Community Psychiatry

    Sowers, Wesley E. / McQuistion, Hunter L. / Runnels, Patrick S. / Feldman, Jacqueline Maus / Ranz, Jules M.

    American Association for Community Psychiatry

    2022  

    Abstract: During the past decade or more, there has been a rapid evolution of mental health services and treatment technologies, shifting psychiatric epidemiology, changes in public behavioral health policy, and increased understanding in medicine regarding ... ...

    Author's details Wesley E. Sowers, MD is Clinical Professor of Psychiatry at the University of Pittsburgh Medical Center and is the Director of the Center for Public Service Psychiatry and its associated Fellowship Program at Western Psychiatric Hospital. He is board certified in Adult Psychiatry with subspecialty certifications in Addiction, Administrative and Community Psychiatry. He is a Past President of the American Association for Community Psychiatry and has served on the Board of Directors of that organization since 1988. He has also been on the Board of the American Association of Psychiatric Administrators since 1999. He has served as Co-Chair of the Mental Health Services Committee of the Group for Advancement of Psychiatry since 2009. From 2008 to 2016 he was co-director of the SAMHSA sponsored Recovery to Practice curriculum development project for psychiatry. Dr. Sowers is a graduate of Brown University and Northwestern University Medical School. He completed residencies at the Cook Co
    Abstract During the past decade or more, there has been a rapid evolution of mental health services and treatment technologies, shifting psychiatric epidemiology, changes in public behavioral health policy, and increased understanding in medicine regarding approaches to clinical work that focus on patient-centeredness. These contemporary issues need to be articulated in a comprehensive format. The American Association of Community Psychiatrists (AACP), a professional organization internationally rec...
    Keywords psychiatricepidemiology ; Trauma-basedinterventions ; behavioralhealthcarefinancing ; communitypsychiatricpractice ; evidence-basedintervention ; mentalhealthrecovery ; person-centeredpatientcare ; Psychiatric Epidemiology ; Trauma-based interventions ; behavioral healthcare financing ; community psychiatric practice ; evidence-based intervention ; mental health recovery ; person-centered patient care
    Language English
    Size 932 p.
    Edition 2
    Publisher Springer International Publishing
    Document type Book
    Note PDA Manuell_16
    Format 183 x 260 x 55
    ISBN 9783031102387 ; 303110238X
    Database PDA

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  2. Article ; Online: A Conceptual Framework for Building Individual and Team Capabilities to Provide Effective Longitudinal, Relationship-Based Clinical Case Management.

    Runnels, Patrick / Penman, James / Schreiber, Steve / Dolber, Trygve / Lee, Kipum / Pronovost, Peter J

    Population health management

    2023  Volume 26, Issue 6, Page(s) 408–412

    Abstract: Individuals with complex, chronic diseases represent 5% of the population but consume 50% of the costs of care. These patients ... ...

    Abstract Individuals with complex, chronic diseases represent 5% of the population but consume 50% of the costs of care. These patients have
    MeSH term(s) Humans ; Case Management
    Language English
    Publishing date 2023-11-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2454546-6
    ISSN 1942-7905 ; 1942-7891
    ISSN (online) 1942-7905
    ISSN 1942-7891
    DOI 10.1089/pop.2023.0165
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  3. Article ; Online: Integrating primary care into a community mental health center.

    Antenucci, Christina / Schreiber, Steven / Clegg, Kathleen / Runnels, Patrick

    The Journal of family practice

    2021  Volume 70, Issue 3, Page(s) 137–139

    Abstract: Our initiation of a reverse-integration practice model revealed numerous advantages and rewards, as well as many challenges, for which we found solutions. ...

    Abstract Our initiation of a reverse-integration practice model revealed numerous advantages and rewards, as well as many challenges, for which we found solutions.
    MeSH term(s) Community Mental Health Centers/organization & administration ; Delivery of Health Care, Integrated/organization & administration ; Family Practice/methods ; Humans ; Mental Disorders/therapy ; Physician-Patient Relations ; Practice Patterns, Physicians'/organization & administration ; Primary Health Care/organization & administration
    Language English
    Publishing date 2021-07-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 197883-4
    ISSN 1533-7294 ; 0094-3509
    ISSN (online) 1533-7294
    ISSN 0094-3509
    DOI 10.12788/jfp.0173
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  4. Article ; Online: First Case Report of Intubation With a Total Control Introducer and a Hyperangulated Video Laryngoscope.

    Pollard, Jacob / Runnels, Sean / Warrick, Christine

    A&A practice

    2020  Volume 14, Issue 11, Page(s) e01310

    Abstract: We describe the first use of an articulating Total Control Introducer (TCI) and video laryngoscope (VL) to guide intubation of a patient with known difficult airway. The patient was an 84-year-old woman with a Mallampati IV airway assessment, small mouth ...

    Abstract We describe the first use of an articulating Total Control Introducer (TCI) and video laryngoscope (VL) to guide intubation of a patient with known difficult airway. The patient was an 84-year-old woman with a Mallampati IV airway assessment, small mouth opening, limited neck extension, and micrognathia. We utilized a VL to visualize the glottis and an articulating TCI for endotracheal tube placement. Anteflexion and retroflexion of the introducer tip allowed dynamic navigation through the upper airway and into the trachea. Intubation was performed on first attempt without complications.
    MeSH term(s) Aged, 80 and over ; Female ; Humans ; Intubation, Intratracheal ; Laryngoscopes ; Laryngoscopy ; Neck ; Trachea
    Language English
    Publishing date 2020-09-28
    Publishing country United States
    Document type Case Reports ; Journal Article
    ISSN 2575-3126
    ISSN (online) 2575-3126
    DOI 10.1213/XAA.0000000000001310
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  5. Article ; Online: An Online Calculator to Better Understand the Impact of False-Negative COVID-19 Polymerase Chain Reaction Test Results in the Context of Anesthesia Providers.

    Runnels, Sean / Pearson, John Frederick / Samuels, Jon Dean / Panchamia, Rohan Kirit

    JMIR perioperative medicine

    2021  Volume 4, Issue 1, Page(s) e26316

    Abstract: What does the COVID-19 false-negative exposure problem mean in the context of a local anesthesia practice? We present a customizable online calculator designed to quantify and better understand individual and aggregate provider exposure risk. ...

    Abstract What does the COVID-19 false-negative exposure problem mean in the context of a local anesthesia practice? We present a customizable online calculator designed to quantify and better understand individual and aggregate provider exposure risk.
    Language English
    Publishing date 2021-04-14
    Publishing country Canada
    Document type Journal Article
    ISSN 2561-9128
    ISSN (online) 2561-9128
    DOI 10.2196/26316
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  6. Article ; Online: The Utah model: mental bandwidth and strategic risk generation in COVID-19 airway management.

    Runnels, S / Ferranti, D / Davis, A N / Pollard, J

    Anaesthesia

    2020  Volume 75, Issue 7, Page(s) 967–968

    MeSH term(s) Airway Management/methods ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/prevention & control ; Humans ; Pandemics/prevention & control ; Pneumonia, Viral/prevention & control ; Risk ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-04-25
    Publishing country England
    Document type Letter
    ZDB-ID 80033-8
    ISSN 1365-2044 ; 0003-2409
    ISSN (online) 1365-2044
    ISSN 0003-2409
    DOI 10.1111/anae.15086
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    Zs.A 388: Show issues Location:
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  7. Article: Burn injury upregulates the activity and gene expression of the 20 S proteasome in rat skeletal muscle.

    Fang, C H / Li, B G / Fischer, D R / Wang, J J / Runnels, H A / Monaco, J J / Hasselgren, P O

    Clinical science (London, England : 1979)

    2000  Volume 99, Issue 3, Page(s) 181–187

    Abstract: ... whereafter they are recognized, unfolded and degraded by the multicatalytic 26 S protease complex. The 20 S ... proteasome is the catalytic core of the 26 S protease complex. The influence of burn injury on the expression ... and activity of the 20 S proteasome has not been reported. We tested the hypothesis that burn injury ...

    Abstract There is evidence that burn injury stimulates ubiquitin-proteasome-dependent protein breakdown in skeletal muscle. In this proteolytic pathway, protein substrates are conjugated to multiple molecules of ubiquitin, whereafter they are recognized, unfolded and degraded by the multicatalytic 26 S protease complex. The 20 S proteasome is the catalytic core of the 26 S protease complex. The influence of burn injury on the expression and activity of the 20 S proteasome has not been reported. We tested the hypothesis that burn injury increases 20 S proteasome activity and the expression of mRNA for the 20 S proteasome subunits RC3 and RC7. Proteolytic activity of isolated 20 S proteasomes, assessed as activity against fluorogenic peptide substrates, was increased in extensor digitorum longus muscles from burned rats. Northern-blot analysis revealed that the expression of mRNA for RC3 and RC7 was increased by 100% and 80% respectively following burn injury. Increased activity and expression of the 20 S proteasome in muscles from burned rats support the concept that burn-induced muscle cachexia is at least, in part, regulated by the ubiquitin-proteasome proteolytic pathway.
    MeSH term(s) Animals ; Blotting, Northern ; Blotting, Western ; Burns/enzymology ; Cachexia/physiopathology ; Cysteine Endopeptidases/genetics ; Cysteine Endopeptidases/metabolism ; Male ; Multienzyme Complexes/genetics ; Multienzyme Complexes/metabolism ; Muscle, Skeletal/enzymology ; Proteasome Endopeptidase Complex ; RNA, Messenger/genetics ; Rats ; Rats, Sprague-Dawley ; Up-Regulation
    Chemical Substances Multienzyme Complexes ; RNA, Messenger ; Cysteine Endopeptidases (EC 3.4.22.-) ; Proteasome Endopeptidase Complex (EC 3.4.25.1)
    Language English
    Publishing date 2000-09
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 760216-9
    ISSN 0143-5221 ; 0144-9664
    ISSN 0143-5221 ; 0144-9664
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    Ua VI Zs.220 -Suppl.: Show issues Location:
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  8. Book ; Online: Automated determination of grain boundary energy and potential-dependence using the OpenKIM framework

    Waters, Brendon / Karls, Daniel S. / Nikiforov, Ilia / Elliott, Ryan S. / Tadmor, Ellad B. / Runnels, Brandon

    2022  

    Abstract: We present a systematic methodology, built within the Open Knowledgebase of Interatomic Models (OpenKIM) framework (https://openkim.org), for quantifying properties of grain boundaries (GBs) for arbitrary interatomic potentials (IPs), GB character, and ... ...

    Abstract We present a systematic methodology, built within the Open Knowledgebase of Interatomic Models (OpenKIM) framework (https://openkim.org), for quantifying properties of grain boundaries (GBs) for arbitrary interatomic potentials (IPs), GB character, and lattice structure and species. The framework currently generates results for symmetric tilt GBs in cubic materials, but can be readily extended to other types of boundaries. In this paper, GB energy data are presented that were generated automatically for Al, Ni, Cu, Fe, and Mo with 225 IPs; the system is installed on openkim.org and will continue to generate results for all new IPs uploaded to OpenKIM. The results from the atomistic calculations are compared to the lattice matching model, which is a semi-analytic geometric model for approximating GB energy. It is determined that the energy predicted by all IPs (that are stable for the given boundary type) correlate closely with the energy from the model, up to a multiplicative factor. It thus is concluded that the qualitative form of the GB energy versus tilt angle is dominated more by geometry than the choice of IP, but that the IP can strongly affect the energy level. The spread in GB energy predictions across the ensemble of IPs in OpenKIM provides a measure of uncertainty for GB energy predictions by classical IPs.
    Keywords Condensed Matter - Materials Science
    Subject code 541
    Publishing date 2022-12-22
    Publishing country us
    Document type Book ; Online
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  9. Article ; Online: Editor's Note: Targeting Akt and Heat Shock Protein 90 Produces Synergistic Multiple Myeloma Cell Cytotoxicity in the Bone Marrow Microenvironment.

    Huston, Alissa / Leleu, Xavier / Jia, Xiaoying / Moreau, Anne-Sophie / Ngo, Hai T / Runnels, Judith / Anderson, Judy / Alsayed, Yazan / Roccaro, Aldo / Vallet, Sonia / Hatjiharissi, Evdoxia / Tai, Yu-Tsu / Sportelli, Peter / Munshi, Nikhil / Richardson, Paul / Hideshima, Teru / Roodman, David G / Anderson, Kenneth C / Ghobrial, Irene M

    Clinical cancer research : an official journal of the American Association for Cancer Research

    2024  Volume 30, Issue 4, Page(s) 922

    Language English
    Publishing date 2024-02-16
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 1225457-5
    ISSN 1557-3265 ; 1078-0432
    ISSN (online) 1557-3265
    ISSN 1078-0432
    DOI 10.1158/1078-0432.CCR-24-0181
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  10. Article ; Online: Sex and Gender Appraisal Tool-Systematic Reviews-2 and Participation-To-Prevalence Ratio assessed to whom the evidence applies in sepsis reviews.

    Antequera, A / Stallings, E / Henry, R S / Lopez-Alcalde, J / Runnels, V / Tudiver, S / Tugwell, P / Welch, V

    Journal of clinical epidemiology

    2021  Volume 142, Page(s) 119–132

    Abstract: Objectives: To revise a sex and gender appraisal tool for systematic reviews (SGAT-SR) and apply it to Cochrane sepsis reviews.: Study design and setting: The revision process was informed by existing literature on sex, gender, intersectionality, and ...

    Abstract Objectives: To revise a sex and gender appraisal tool for systematic reviews (SGAT-SR) and apply it to Cochrane sepsis reviews.
    Study design and setting: The revision process was informed by existing literature on sex, gender, intersectionality, and feedback from an expert advisory board. We revised the items to consider additional factors associated with health inequities and appraised sex and gender considerations using the SGAT-SR-2 and female Participation-to-Prevalence Ratio (PPR) in Cochrane sepsis reviews.
    Results: SGAT-SR-2 consists of 19 questions appraising the review's sections and use of the terms sex and gender. amongst 71 SRs assessed, 50.7% included at least one tool item, the most frequent being the number of participants by sex or gender at included study-level (24/71 reviews). Only four reviews provided disaggregated data for the full set of included trials, while two considered other equity-related factors. Reviews rarely appraised possible similarities and differences across sex and gender. In half of a subset of reviews, female participants were under-represented relative to their share of the sepsis population (PPR<0.8).
    Conclusion: The SGAT-SR-2 tool and the PPR can support the design and appraisal of systematic reviews to assess sex and gender considerations, address to whom evidence applies, and determine future research needs.
    MeSH term(s) Female ; Humans ; Male ; Prevalence ; Publications ; Sepsis/epidemiology ; Systematic Reviews as Topic
    Language English
    Publishing date 2021-11-08
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 639306-8
    ISSN 1878-5921 ; 0895-4356
    ISSN (online) 1878-5921
    ISSN 0895-4356
    DOI 10.1016/j.jclinepi.2021.11.006
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