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Article ; Online: The Utility of Anti-Covid-19 Desks in Italy, Doubts and Criticism.

Bergamin, Marco / Musumeci, Giuseppe

Journal of functional morphology and kinesiology

2020 Volume 6, Issue 1

Abstract: As of the 14th of September, Italy has been considered one of the more susceptible nations in terms of risk of increase for Sars-Cov-2 contagion [ ... ]. ...

Abstract	As of the 14th of September, Italy has been considered one of the more susceptible nations in terms of risk of increase for Sars-Cov-2 contagion [...].
Language	English
Publishing date	2020-12-30
Publishing country	Switzerland
Document type	Editorial
ISSN	2411-5142
ISSN (online)	2411-5142
DOI	10.3390/jfmk6010002
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: The social media gym-class: another lesson learnt from COVID-19 lockdown.

Cugusi, Lucia / Di Blasio, Andrea / Bergamin, Marco

Sport sciences for health

2021 Volume 17, Issue 2, Page(s) 487–488

Language	English
Publishing date	2021-03-06
Publishing country	Italy
Document type	Journal Article
ZDB-ID	2244652-7
ISSN	1825-1234 ; 1824-7490
ISSN (online)	1825-1234
ISSN	1824-7490
DOI	10.1007/s11332-021-00747-6
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Article ; Online: Introductory Note to the Document "Il sistema di collegamenti bibliografici nell'archivio della cooperazione di T. Giordano, con la collaborazione di S. Peruginelli"

Giovanni Bergamin

JLIS.it, Vol 11, Iss

2020 Volume 2

Abstract: ... that it has been developed within the framework of an E-R model. ...

Abstract	The purpose of this article is to introduce a seminal 1984 document on the structure of the “system of bibliographic links” of the Italian national library service (named SBN or Servizio Bibliotecario Nazionale). To some extent thirteen years before FRBR, the Entity-Relationship Model has been used to identify Entities, Attributes and Relationships within bibliographic records. The 1984 document can also be seen as a first step of a long path (which has not yet been concluded) of use of E-R model: also the IFLA LRM (2017) claims that it has been developed within the framework of an E-R model.
Keywords	SBN (Servizio Bibliotecario Nazionale) ; E-R (Entity-Relationship) Model ; UNIMARC ; Domanovszky ; Bibliography. Library science. Information resources ; Z
Language	English
Publishing date	2020-05-01T00:00:00Z
Publisher	Firenze University Press
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Introductory Note to the Document "Il sistema di collegamenti bibliografici nell'archivio della cooperazione di T. Giordano, con la collaborazione di S. Peruginelli"

Giovanni Bergamin

JLIS.it, Vol 11, Iss 2, Pp 82-

2020 Volume 90

Abstract: ... that it has been developed within the framework of an E-R model. ...

Abstract	The purpose of this article is to introduce a seminal 1984 document on the structure of the “system of bibliographic links” of the Italian national library service (named SBN or Servizio Bibliotecario Nazionale). To some extent thirteen years before FRBR, the Entity-Relationship Model has been used to identify Entities, Attributes and Relationships within bibliographic records. The 1984 document can also be seen as a first step of a long path (which has not yet been concluded) of use of E-R model: also the IFLA LRM (2017) claims that it has been developed within the framework of an E-R model.
Keywords	sbn (servizio bibliotecario nazionale) ; modello er (entità-relazione) ; unimarc ; domanovszky ; ákos ; Bibliography. Library science. Information resources ; Z
Language	English
Publishing date	2020-05-01T00:00:00Z
Publisher	Firenze University Press
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Introductory Note to the Document "Il sistema di collegamenti bibliografici nell'archivio della cooperazione di T. Giordano, con la collaborazione di S. Peruginelli"

Giovanni Bergamin

JLIS.it, Vol 11, Iss

2020 Volume 2

Abstract: ... that it has been developed within the framework of an E-R model. ...

Abstract	The purpose of this article is to introduce a seminal 1984 document on the structure of the “system of bibliographic links” of the Italian national library service (named SBN or Servizio Bibliotecario Nazionale). To some extent thirteen years before FRBR, the Entity-Relationship Model has been used to identify Entities, Attributes and Relationships within bibliographic records. The 1984 document can also be seen as a first step of a long path (which has not yet been concluded) of use of E-R model: also the IFLA LRM (2017) claims that it has been developed within the framework of an E-R model.
Keywords	SBN (Servizio Bibliotecario Nazionale) ; E-R (Entity-Relationship) Model ; UNIMARC ; Domanovszky ; Bibliography. Library science. Information resources ; Z
Language	English
Publishing date	2020-05-01T00:00:00Z
Publisher	Firenze University Press
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: A Bayesian method to infer copy number clones from single-cell RNA and ATAC sequencing.

Patruno, Lucrezia / Milite, Salvatore / Bergamin, Riccardo / Calonaci, Nicola / D'Onofrio, Alberto / Anselmi, Fabio / Antoniotti, Marco / Graudenzi, Alex / Caravagna, Giulio

PLoS computational biology

2023 Volume 19, Issue 11, Page(s) e1011557

Abstract: ... straightforward to compare their expression and chromatin profiles. The framework, implemented on GPU and tested ...

Abstract	Single-cell RNA and ATAC sequencing technologies enable the examination of gene expression and chromatin accessibility in individual cells, providing insights into cellular phenotypes. In cancer research, it is important to consistently analyze these states within an evolutionary context on genetic clones. Here we present CONGAS+, a Bayesian model to map single-cell RNA and ATAC profiles onto the latent space of copy number clones. CONGAS+ clusters cells into tumour subclones with similar ploidy, rendering straightforward to compare their expression and chromatin profiles. The framework, implemented on GPU and tested on real and simulated data, scales to analyse seamlessly thousands of cells, demonstrating better performance than single-molecule models, and supporting new multi-omics assays. In prostate cancer, lymphoma and basal cell carcinoma, CONGAS+ successfully identifies complex subclonal architectures while providing a coherent mapping between ATAC and RNA, facilitating the study of genotype-phenotype maps and their connection to genomic instability.
MeSH term(s)	RNA/genetics ; Bayes Theorem ; DNA Copy Number Variations/genetics ; Clone Cells ; High-Throughput Nucleotide Sequencing/methods ; Chromatin
Chemical Substances	RNA (63231-63-0) ; Chromatin
Language	English
Publishing date	2023-11-02
Publishing country	United States
Document type	Journal Article
ZDB-ID	2193340-6
ISSN	1553-7358 ; 1553-734X
ISSN (online)	1553-7358
ISSN	1553-734X
DOI	10.1371/journal.pcbi.1011557
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: 3D printing and testing of rose thorns or limpet teeth inspired anchor device for tendon tissue repair.

Rodriguez Reinoso, Mariana / Civera, Marco / Burgio, Vito / Bergamin, Federica / Ruiz, Oliver Grimaldo / Pugno, Nicola Maria / Surace, Cecilia

Acta of bioengineering and biomechanics

2023 Volume 23, Issue 4, Page(s) 63–74

Abstract: Purposes: Advancements in medical technology have enabled medical specialists to resolve significant problems concerning tendon injuries. However, despite the latest improvements, surgical tendon repair remains challenging. This study aimed to explore ... ...

Abstract	Purposes: Advancements in medical technology have enabled medical specialists to resolve significant problems concerning tendon injuries. However, despite the latest improvements, surgical tendon repair remains challenging. This study aimed to explore the capabilities of the current state-of-the-art technologies for implantable devices. Methods: After performing extensive patent landscaping and literature review, an anchored tissue fixation device was deemed the most suitable candidate. This design was firstly investigated numerically, realizing a Finite Element Model of the device anchored to two swine tendons stumps, to simulate its application on a severed tendon. Two different hook designs, both bio-inspired, were tested while retaining the same device geometry and anchoring strategy. Then, the applicability of a 3D-printed prototype was tested on swine tendons. Finally, the device-tendon stumps ensemble was subjected to uniaxial tensile tests. Results: The results show that the investigated device enables a better load distribution during the immobilized limb period in comparison to standard suture-based approaches, yet it still presents several design flaws. Conclusions: The current implantable solutions do not ensure an optimal result in terms of strength recovery. This and other weak points of the currently available proposals will serve as a starting point for future works on bio-inspired implantable devices for tendon repair.
Language	English
Publishing date	2023-06-21
Publishing country	Poland
Document type	Journal Article
ZDB-ID	2559094-7
ISSN	1509-409X
ISSN	1509-409X
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Cardiometabolic, functional, and psychosocial effects of a remotely supervised home-based exercise program in individuals with type 2 diabetes (RED study): study protocol for a randomized clinical trial.

Rodrigues, Samara Nickel / Delevatti, Rodrigo Sudatti / Carvalho, Mauricio Tatsch Ximenes / Bullo, Valentina / Bergamin, Marco / Alberton, Cristine Lima

Trials

2023 Volume 24, Issue 1, Page(s) 679

Abstract: Background: Type 2 diabetes mellitus (T2D) is a serious global health problem, and exercise is considered an essential non-pharmacological tool in T2D prevention and treatment. During periods of social isolation experienced by the COVID-19 pandemic, ... ...

Abstract	Background: Type 2 diabetes mellitus (T2D) is a serious global health problem, and exercise is considered an essential non-pharmacological tool in T2D prevention and treatment. During periods of social isolation experienced by the COVID-19 pandemic, home-based exercise programs were strongly recommended as a strategy to facilitate exercise practice and reduce the negative impacts of social isolation. Remotely supervised exercise stands out as an easily accessible strategy after the pandemic, as it is a tool that aims to facilitate access to exercise by this population. The purpose of the RED study is to verify the effects of a remotely supervised home-based exercise program compared to a control group on cardiometabolic, functional, and psychosocial outcomes in patients with T2D. Methods: Participants are randomized into the control group (CG) and the intervention group (IG). Participants allocated to the CG receive recommendations for the practice of physical activity based on information from chapters of the Physical Activity Guide for the Brazilian Population, while the IG will perform a 12-week home-based exercise program supervised remotely by video call. The intervention has a weekly frequency of two sessions per week on non-consecutive days during the first 6 weeks and three sessions per week on non-consecutive days for the remaining 6 weeks. The RED study has HbA1c as the primary outcome, and the participants' cardiometabolic, functional, and psychosocial parameters are assessed at baseline (week 0) and post-intervention (week 13). Discussion: Expected results of the proposed study will provide the knowledge base of health professionals and deliver more evidence for a growing area, i.e., home-based exercise and T2D. Additionally, this protocol aims to verify and demonstrate whether this program can be accessible and effective for different health outcomes in patients with T2D. Trial registration: The RED study protocol was prospectively registered at ClinicalTrials.gov (NCT05362071). Date registered April 6, 2022. https://clinicaltrials.gov/ct2/show/NCT05362071 .
MeSH term(s)	Humans ; COVID-19 ; Diabetes Mellitus, Type 2/diagnosis ; Diabetes Mellitus, Type 2/therapy ; Pandemics ; Exercise Therapy/methods ; Cardiovascular Diseases ; Randomized Controlled Trials as Topic
Language	English
Publishing date	2023-10-19
Publishing country	England
Document type	Clinical Trial Protocol ; Journal Article
ZDB-ID	2040523-6
ISSN	1745-6215 ; 1468-6694 ; 1745-6215
ISSN (online)	1745-6215
ISSN	1468-6694 ; 1745-6215
DOI	10.1186/s13063-023-07704-3
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Effects of a remotely supervised physical training program combined with cognitive training for older individuals at increased risk of clinical-functional vulnerability: study protocol for a randomized clinical trial.

Berní, Franciele Costa / Kanitz, Ana Carolina / Miranda, Camila / de Oliveira, Dener Budziarek / Bergamin, Marco / Bullo, Valentina / Schaun, Gustavo Zaccaria / Alberton, Cristine Lima

Trials

2023 Volume 24, Issue 1, Page(s) 547

Abstract: Background: Despite the robust body of evidence for the benefits of home-based physical exercise, there is still a paucity of data on the benefits of home-based cognitive training for older adults, especially in those at increased risk of clinical- ... ...

Abstract	Background: Despite the robust body of evidence for the benefits of home-based physical exercise, there is still a paucity of data on the benefits of home-based cognitive training for older adults, especially in those at increased risk of clinical-functional vulnerability. As such, the present study aims to compare the chronic effects of a telehealth-delivered physical training intervention alone or combined with a cognitive training program in older adults at increased clinical-functional vulnerability risk. Methods: A randomized clinical trial will be conducted including 62 sedentary older individuals classified as at increased risk of clinical-functional vulnerability based on their Clinical-Functional Vulnerability Index score. Participants will be randomly allocated in a 1:1 ratio to one of two groups, an intervention group including physical training combined with cognitive training, or an active control group including physical training alone. Both groups will receive home-based supervised training remotely for 12 weeks and will be assessed for the primary and secondary outcomes of the study before and after the training period. Primary outcomes include cognitive function and dynamic balance with a dual task. Secondary outcomes encompass physical, cognitive, and occupational performance, functional capacity, quality of life, and anxiety and depression symptoms, as well as hemodynamic measures. Data analysis will be performed by intention-to-treat and per protocol using mixed linear models and Bonferroni's post hoc (α = 0.05). Discussion: Our conceptual hypothesis is that both groups will show improvements in the primary and secondary outcomes. Nevertheless, we expect physical combined with cognitive training to improve cognitive function, dual task, and occupational performance to a greater degree as compared to physical training alone. Trial registration: NCT05309278. Registered on April 4, 2022.
MeSH term(s)	Humans ; Aged ; Cognitive Training ; Quality of Life ; Anxiety ; Anxiety Disorders ; Cognition ; Randomized Controlled Trials as Topic
Language	English
Publishing date	2023-08-21
Publishing country	England
Document type	Clinical Trial Protocol ; Journal Article
ZDB-ID	2040523-6
ISSN	1745-6215 ; 1468-6694 ; 1745-6215
ISSN (online)	1745-6215
ISSN	1468-6694 ; 1745-6215
DOI	10.1186/s13063-023-07567-8
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: A Bayesian method to infer copy number clones from single-cell RNA and ATAC sequencing.

Lucrezia Patruno / Salvatore Milite / Riccardo Bergamin / Nicola Calonaci / Alberto D'Onofrio / Fabio Anselmi / Marco Antoniotti / Alex Graudenzi / Giulio Caravagna

PLoS Computational Biology, Vol 19, Iss 11, p e

2023 Volume 1011557

Abstract: ... straightforward to compare their expression and chromatin profiles. The framework, implemented on GPU and tested ...

Abstract	Single-cell RNA and ATAC sequencing technologies enable the examination of gene expression and chromatin accessibility in individual cells, providing insights into cellular phenotypes. In cancer research, it is important to consistently analyze these states within an evolutionary context on genetic clones. Here we present CONGAS+, a Bayesian model to map single-cell RNA and ATAC profiles onto the latent space of copy number clones. CONGAS+ clusters cells into tumour subclones with similar ploidy, rendering straightforward to compare their expression and chromatin profiles. The framework, implemented on GPU and tested on real and simulated data, scales to analyse seamlessly thousands of cells, demonstrating better performance than single-molecule models, and supporting new multi-omics assays. In prostate cancer, lymphoma and basal cell carcinoma, CONGAS+ successfully identifies complex subclonal architectures while providing a coherent mapping between ATAC and RNA, facilitating the study of genotype-phenotype maps and their connection to genomic instability.
Keywords	Biology (General) ; QH301-705.5
Language	English
Publishing date	2023-11-01T00:00:00Z
Publisher	Public Library of Science (PLoS)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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