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  1. Book: Cholera outbreaks

    Nair, G. Balakrish / Takeda, Yoshifumi

    (Current topics in microbiology and immunology ; 379)

    2014  

    Author's details G. Balakrish Nair ; Yoshifumi Takeda ed
    Series title Current topics in microbiology and immunology ; 379
    Collection
    Keywords Cholera ; Epidemiologie
    Subject Krankheitsverbreitung ; Cholera asiatica ; Cholera epidemica
    Language English
    Size X, 263 S. : Ill., graph. Darst., 235 mm x 155 mm
    Publisher Springer
    Publishing place Berlin u.a.
    Publishing country Germany
    Document type Book
    HBZ-ID HT018322648
    ISBN 978-3-642-55403-2 ; 3-642-55403-2 ; 9783642554049 ; 3642554040
    Database Catalogue ZB MED Medicine, Health

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  2. Book: Vibrio cholerae

    Faruque, Shah M. / Nair, G. Balakrish

    genomics and molecular biology

    2008  

    Author's details Shah M. Faruque and G. Balakrish Nair
    Language English
    Size VI, 218 S. : Ill., graph. Darst.
    Publisher Caister Acad. Press
    Publishing place Norfolk
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT015465080
    ISBN 978-1-904455-33-2 ; 1-904455-33-6
    Database Catalogue ZB MED Medicine, Health

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  3. Article ; Online: Contrasts, contradictions and control of cholera.

    Lonappan, Sophia / Golecha, Ria / Balakrish Nair, G

    Vaccine

    2019  Volume 38 Suppl 1, Page(s) A4–A6

    Abstract: Cholera has been extremely pervasive during the past four decades and continues to remain a significant public health concern. The disease has plagued humankind in the form of seven pandemics since the last two centuries. There is considerable scientific ...

    Abstract Cholera has been extremely pervasive during the past four decades and continues to remain a significant public health concern. The disease has plagued humankind in the form of seven pandemics since the last two centuries. There is considerable scientific evidence based on research on cholera and its etiologic agent Vibrio cholerae, however we are still unable to accurately forecast and pre-empt the occurrence of cholera outbreaks. The commentary discusses the contrasts and contradictions of cholera, its control and its unpredictable nature. Through a multi-sectoral approach and broad stakeholder collaboration cholera control is possible with meticulous country-level planning for early detection and response to outbreaks. The commentary reiterates that every potential death on account of cholera is preventable because of the available knowledge and tools to effectively prevent and treat cholera.
    MeSH term(s) Cholera/epidemiology ; Cholera/prevention & control ; Disease Outbreaks/prevention & control ; Humans ; Vibrio cholerae
    Language English
    Publishing date 2019-08-23
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 605674-x
    ISSN 1873-2518 ; 0264-410X
    ISSN (online) 1873-2518
    ISSN 0264-410X
    DOI 10.1016/j.vaccine.2019.08.022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Gastrointestinal microbiome in the context of Helicobacter pylori infection in stomach and gastroduodenal diseases.

    Retnakumar, R J / Nath, Angitha N / Nair, G Balakrish / Chattopadhyay, Santanu

    Progress in molecular biology and translational science

    2022  Volume 192, Issue 1, Page(s) 53–95

    Abstract: Infectious origins of a set of severe gastroduodenal diseases viz. gastritis, duodenal ulcer, gastric ulcer, gastric adenocarcinoma and gastric mucosa-associated lymphoid tissue (MALT) lymphoma were appreciated only after the discovery of H. pylori in ... ...

    Abstract Infectious origins of a set of severe gastroduodenal diseases viz. gastritis, duodenal ulcer, gastric ulcer, gastric adenocarcinoma and gastric mucosa-associated lymphoid tissue (MALT) lymphoma were appreciated only after the discovery of H. pylori in 1983. In the past two decades, however, findings from many laboratories suggest that apart from H. pylori, several of the trillions of microbes that populate the human gastrointestinal tract and form microbiomes of the respective niches (like oral microbiome, esophageal microbiome, gastric microbiome and intestinal microbiome) may also participate in maintaining the healthy state of stomach and duodenum. Dysbiosis leading to alteration in the relative abundance of the key gastrointestinal microbes is associated with severe gastric diseases. For instance, an increased abundance of genera like Leptotrichia, Prevotella and Veillonella in gastric microbiome and a decreased abundance of Bifidobacterium in intestinal microbiome are associated with gastric cancer. H. pylori infection, apart from causing direct harm to the gastric epithelium by its virulence proteins like vacuolating cytotoxin A (VacA) and cytotoxin associated gene A (CagA), is also capable of triggering dysbiosis in stomach and intestinal microbiomes. In this chapter, we have discussed the possible roles of bacteria, viruses, fungi, archaea, protozoa and helminths in human gastrointestinal tracts in the context of H. pylori infection in stomach and various gastroduodenal diseases.
    MeSH term(s) Humans ; Helicobacter Infections/microbiology ; Helicobacter Infections/pathology ; Helicobacter pylori/genetics ; Gastrointestinal Microbiome ; Dysbiosis/complications ; Antigens, Bacterial/genetics ; Bacterial Proteins/genetics ; Stomach ; Stomach Neoplasms/microbiology ; Cytotoxins
    Chemical Substances Antigens, Bacterial ; Bacterial Proteins ; Cytotoxins
    Language English
    Publishing date 2022-08-18
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2471995-X
    ISSN 1878-0814 ; 0079-6603 ; 1877-1173
    ISSN (online) 1878-0814
    ISSN 0079-6603 ; 1877-1173
    DOI 10.1016/bs.pmbts.2022.07.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Homeostasis and dysbiosis of the gut microbiome in health and disease.

    DAS, Bhabatosh / Nair, G Balakrish

    Journal of biosciences

    2019  Volume 44, Issue 5

    Abstract: The human gastrointestinal tract (GIT) harbors taxonomically and functionally complex microbial ecosystem. The composition of the microbial species in the GIT ecosystem varies among individuals and throughout development. Both environmental factors as ... ...

    Abstract The human gastrointestinal tract (GIT) harbors taxonomically and functionally complex microbial ecosystem. The composition of the microbial species in the GIT ecosystem varies among individuals and throughout development. Both environmental factors as well as host genetics influence the composition and homeostasis of GIT microbiome. Intrinsic GIT microbiome can be characterized in terms of diversity, richness, dynamics and resilience. In healthy individual, microbial communities maintain homeostatic equilibrium and are resistant against perturbations. The resilience and resistance to perturbations of the GIT microbial ecosystem are robust but not absolute. Several factors can affect the homeostatic equilibrium of GIT microbiome and lead to dysbiotic microbiome configuration. Taxonomic and/or functional dysbiosis in the GIT microbiome is associated with numerous health disorders like inflammatory bowel disease (IBD), malnutrition, metabolic disorders, asthma and neurodegenerative diseases. In this review, we discuss our current understanding of homeostasis and dysbiosis of the microbial ecology in the human gut and health disorders that are associated with the microbiome dysbiosis.
    MeSH term(s) Gastrointestinal Microbiome ; Homeostasis ; Humans
    Language English
    Publishing date 2019-11-12
    Publishing country India
    Document type Journal Article ; Review
    ZDB-ID 756157-x
    ISSN 0973-7138 ; 0250-5991
    ISSN (online) 0973-7138
    ISSN 0250-5991
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Homeostasis and dysbiosis of the gut microbiome in health and disease

    Das, Bhabatosh / Nair, G Balakrish

    Journal of biosciences. 2019 Oct., v. 44, no. 5

    2019  

    Abstract: The human gastrointestinal tract (GIT) harbors taxonomically and functionally complex microbial ecosystem. The composition of the microbial species in the GIT ecosystem varies among individuals and throughout development. Both environmental factors as ... ...

    Abstract The human gastrointestinal tract (GIT) harbors taxonomically and functionally complex microbial ecosystem. The composition of the microbial species in the GIT ecosystem varies among individuals and throughout development. Both environmental factors as well as host genetics influence the composition and homeostasis of GIT microbiome. Intrinsic GIT microbiome can be characterized in terms of diversity, richness, dynamics and resilience. In healthy individual, microbial communities maintain homeostatic equilibrium and are resistant against perturbations. The resilience and resistance to perturbations of the GIT microbial ecosystem are robust but not absolute. Several factors can affect the homeostatic equilibrium of GIT microbiome and lead to dysbiotic microbiome configuration. Taxonomic and/or functional dysbiosis in the GIT microbiome is associated with numerous health disorders like inflammatory bowel disease (IBD), malnutrition, metabolic disorders, asthma and neurodegenerative diseases. In this review, we discuss our current understanding of homeostasis and dysbiosis of the microbial ecology in the human gut and health disorders that are associated with the microbiome dysbiosis.
    Keywords asthma ; dysbiosis ; ecosystems ; environmental factors ; gastrointestinal system ; genetics ; homeostasis ; humans ; inflammatory bowel disease ; intestinal microorganisms ; malnutrition ; metabolic diseases ; microbial communities ; microbiome ; neurodegenerative diseases
    Language English
    Dates of publication 2019-10
    Size p. 117.
    Publishing place Springer India
    Document type Article
    Note Review
    ZDB-ID 756157-x
    ISSN 0973-7138 ; 0250-5991
    ISSN (online) 0973-7138
    ISSN 0250-5991
    DOI 10.1007/s12038-019-9926-y
    Database NAL-Catalogue (AGRICOLA)

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  7. Article: Cholera Toxin Production in

    Baek, Yeongjun / Lee, Donghyun / Lee, Jiwon / Yoon, Youngbae / Nair, G Balakrish / Kim, Dong Wook / Kim, Eun Jin

    Frontiers in microbiology

    2020  Volume 11, Page(s) 825

    Abstract: ... Vibrio ... ...

    Abstract Vibrio cholerae
    Language English
    Publishing date 2020-05-05
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2020.00825
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Cholera outbreaks. Preface.

    Nair, G Balakrish / Takeda, Yoshifumi

    Current topics in microbiology and immunology

    2014  Volume 379, Page(s) v – vii

    MeSH term(s) Cholera/epidemiology ; Disease Outbreaks ; Humans
    Language English
    Publishing date 2014
    Publishing country Germany
    Document type Introductory Journal Article
    ISSN 0070-217X
    ISSN 0070-217X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Book: Cholera outbreaks

    Nair, G. Balakrish / Takeda, Yoshifumi

    (Current topics in microbiology and immunology ; 379)

    2014  

    Author's details G. Balakrish Nair, Yoshifumi Takeda, eds
    Series title Current topics in microbiology and immunology ; 379
    Language English
    Size x, 263 S., Ill., graph. Darst.
    Publisher Springer
    Publishing place Berlin u.a.
    Document type Book
    ISBN 9783642554032 ; 3642554032
    Database Friedrich Loeffler-Institute, Federal Research Institute for Animal Health

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  10. Book: Cholera outbreaks

    Nair, G. Balakrish / Takeda, Yoshifumi

    (Current topics in microbiology and immunology ; 379)

    2014  

    Author's details G. Balakrish Nair, Yoshifumi Takeda, eds
    Series title Current topics in microbiology and immunology ; 379
    Language English
    Size x, 263 S., Ill., graph. Darst.
    Publisher Springer
    Publishing place Berlin u.a.
    Document type Book
    ISBN 9783642554032 ; 3642554032
    Database Special collection on veterinary medicine and general parasitology

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