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Article ; Online: A Flexible Carbon Nanotube Sen-Memory Device.

Qu, Ting-Yu / Sun, Yun / Chen, Mao-Lin / Liu, Zhi-Bo / Zhu, Qian-Bing / Wang, Bing-Wei / Zhao, Tian-Yang / Liu, Chi / Tan, Jun / Qiu, Song / Li, Qing-Wen / Han, Zheng / Wang, Wei / Cheng, Hui-Ming / Sun, Dong-Ming

Advanced materials (Deerfield Beach, Fla.)

2020 Volume 32, Issue 9, Page(s) e1907288

Abstract: ... called "sen-memory", that exhibits the dual functionality of sensing and memory in a monolithic ...

Abstract	In a modern electronics system, charge-coupled devices and data storage devices are the two most indispensable components. Although there has been rapid and independent progress in their development during the last three decades, a cofunctionality of both sensing and memory at single-unit level is yet premature for flexible electronics. For wearable electronics that work in ultralow power conditions and involve strains, conventional sensing-and-memory systems suffer from low sensitivity and are not able to directly transform sensed information into sufficient memory. Here, a new transformative device is demonstrated, which is called "sen-memory", that exhibits the dual functionality of sensing and memory in a monolithic integrated circuit. The active channel of the device is formed by a carbon nanotube thin film and the floating gate is formed by a controllably oxidized aluminum nanoparticle array for electrical- and optical-programming. The device exhibits a high on-off current ratio of ≈10
Language	English
Publishing date	2020-01-24
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1474949-X
ISSN	1521-4095 ; 0935-9648
ISSN (online)	1521-4095
ISSN	0935-9648
DOI	10.1002/adma.201907288
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Article: Sun Yat-sen (1866-1925): physician revolutionist.

Tan, Siang Yong / Yip, Angela

Singapore medical journal

2013 Volume 54, Issue 1, Page(s) 9–10

MeSH term(s)	China ; History, 19th Century ; History, 20th Century ; Humans ; Male ; Philately ; Physicians/history ; Politics ; Taiwan
Language	English
Publishing date	2013-01
Publishing country	Singapore
Document type	Historical Article ; Journal Article
ZDB-ID	604319-7
ISSN	0037-5675
ISSN	0037-5675
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Article: SEN virus infection in patients on peritoneal dialysis.

Hsu, Bang-Gee / Wang, Li-Yu / Hu, Chi-Tan / Wang, Chih-Hsien / Fang, Te-Chao / Lin, Hans Hsienhong

Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis

2006 Volume 27, Issue 1, Page(s) 74–78

Abstract: Background: Many reports have demonstrated SEN virus (SEN-V) infection rates in hemodialysis ... patients, but the SEN-V infection rate in peritoneal dialysis (PD) patients has never been reported ... In this study, we determined the prevalence rate of SEN-V viremia in a PD population.: Methods: Serum samples ...

Abstract	Background: Many reports have demonstrated SEN virus (SEN-V) infection rates in hemodialysis patients, but the SEN-V infection rate in peritoneal dialysis (PD) patients has never been reported. In this study, we determined the prevalence rate of SEN-V viremia in a PD population. Methods: Serum samples from 47 PD patients and a control group of 43 subjects from the general population at their health examination were assayed for SEN-V-D and -H viremia using polymerase chain reaction. Results: The proportions of female gender (p = 0.001), previous transfusion (p < 0.0001), and higher mean serum AST level (p = 0.012) were significantly higher in PD patients. The prevalence rates of SEN-V-D and/or -H viremia were not significantly different between PD patients and controls (27.7% vs 32.6%). SEN-V-D(+) patients had lower mean duration of PD than SEN-V(-) patients. Mean ALT level was significantly lower in SEN-V-H(+) than in SEN-V(-) patients (12.8 +/- 5.8 vs 19.6 +/- 12.1 (IU/L), p = 0.025). None of the SEN-V-infected PD patients had overt clinical or biochemical signs of liver disease. There were no statistically significant differences in prevalence of SEN-V-D and/or -H viremia between automated PD (APD) patients and continuous ambulatory PD (CAPD) patients. Conclusions: These results indicate that the SEN-V infection rate is not different between healthy individuals and PD patients. Infection with SEN-V is not associated with evident liver disease in PD patients and SEN-V infection rate is not different between APD patients and CAPD patients.
MeSH term(s)	DNA Virus Infections/epidemiology ; DNA Virus Infections/virology ; DNA, Viral/analysis ; Female ; Humans ; Male ; Middle Aged ; Peritoneal Dialysis/adverse effects ; Peritonitis/epidemiology ; Peritonitis/virology ; Polymerase Chain Reaction ; Prevalence ; Retrospective Studies ; Risk Factors ; Taiwan/epidemiology ; Torque teno virus/genetics
Chemical Substances	DNA, Viral
Language	English
Publishing date	2006-12-08
Publishing country	United States
Document type	Journal Article
ZDB-ID	645010-6
ISSN	0896-8608
ISSN	0896-8608
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Article: Sub-acute pain after childbirth during COVID-19 pandemic: A secondary analysis of A prospective clinical trial.

Tan, Chin Wen / Sultana, Rehena / Chang, Azriel Nicol / Tan, Hon Sen / Sng, Ban Leong

Heliyon

2024 Volume 10, Issue 6, Page(s) e27240

Abstract: Background: COVID-19 pandemic could bring great impact upon the psychological statuses of post-partum women, but no clear evidence was provided yet as to COVID-19 would also affect their pain profile during post-partum period. We determined if pain and ... ...

Abstract	Background: COVID-19 pandemic could bring great impact upon the psychological statuses of post-partum women, but no clear evidence was provided yet as to COVID-19 would also affect their pain profile during post-partum period. We determined if pain and psychological vulnerabilities, obstetric factors, and labor analgesia were associated with sub-acute pain after childbirth (SAPC; ongoing pain related to delivery at post-partum 4 weeks or more) during COVID-19 pandemic. Methods: We included women having a singleton pregnancy of ≥36 gestational weeks. The recruited women were given pre-delivery questionnaires to measure their pain and psychological vulnerabilities. At post-partum 6-10 weeks, an online survey was conducted to collect data on post-partum pain information. Results: Of the 880 recruited women, 816 completed the post-partum pain survey, with 99 (12.1%) having developed SAPC. Giving birth during COVID-19 pandemic (adjusted odds ratio (aOR) 1.64, 95%CI 1.04 to 2.57), greater pre-delivery central sensitization (aOR 1.02, 95%CI 1.00 to 1.04), greater number of pain relief administered (aOR 1.49, 95%CI 1.18 to 1.89), having had artificial rupture of membrane and oxytocic during labor onset (aOR 3.00, 95%CI 1.66 to 5.40), greater volume of blood loss during delivery (every 100 ml; aOR 1.27, 95%CI 1.11 to 1.44), having had third-degree tear during delivery (aOR 4.40, 95%CI 1.33 to 14.51), and greater infant height (aOR 1.14, 95%CI 1.01 to 1.30) were independently associated with greater risk of SAPC. Having greater general health score was protective against the risk of SAPC (aOR 0.99, 95% CI 0.97 to 0.999) (Area under the curve (AUC) = 0.74). Conclusions: The generated multivariable association model may help us better understand the shift in pain and psychological aspects of women during COVID-19 pandemic.
Language	English
Publishing date	2024-02-29
Publishing country	England
Document type	Journal Article
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2024.e27240
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Article: Investigating Factors Associated with the Development of Postnatal Depression After Cesarean Delivery: A Validation Cohort Study.

Tan, Daryl Jian An / Sultana, Rehena / Chow, Sheryl Yu Xuan / Tan, Chin Wen / Tan, Hon Sen / Chen, Helen Yu / Chua, Tze-Ern / Sng, Ban Leong

Neuropsychiatric disease and treatment

2024 Volume 20, Page(s) 439–447

Abstract: Purpose: This study aimed to validate a proposed association model previously published to determine the clinical relevance of pre-operative determinants in the development of PND after Cesarean delivery (CD).: Patients and methods: Parturients ... ...

Abstract	Purpose: This study aimed to validate a proposed association model previously published to determine the clinical relevance of pre-operative determinants in the development of PND after Cesarean delivery (CD). Patients and methods: Parturients undergoing elective CD under neuraxial anesthesia were recruited for a prospective cohort study between Oct 2021 and Oct 2022 at KK Women's and Children's Hospital, Singapore. Predelivery pain, psychological and mechanical temporal summation, and demographic data were recorded. A follow-up survey was conducted at 6 to 10 weeks after CD. The primary outcome was the incidence of PND, defined as an Edinburgh Postnatal Depression Scale (EPDS) score ≥ 10. Results: A total of 180 patients were recruited for validation. PND 6 to 10 weeks post-delivery occurred in 18.9% of recruited parturients. Multivariate regression analyses showed that higher pre-operative CSI scores (p=0.0156), higher anxiety levels about upcoming surgery (p=0.0429), increased pre-operative pain scores on movement (p=0.0110), and higher pre-operative HADS subscale scores on anxiety (p=0.0041) were independently associated with the development of PND weeks post-CD. Lower anticipation of pain medication needs (p=0.0038) was independently associated with the development of PND post-CD. The area under curve (AUC) of this multivariable model (training cohort), internal cross validation (training cohort) and external cross validation (validation cohort) were 0.818 (95% CI, 0.746 to 0.889), 0.785 (95% CI, 0.707 to 0.864) and 0.604 (95% CI, 0.497 to 0.710) respectively. Conclusion: The proposed model performed well in a local population. Further refinement is necessary to test the proposed model in populations with social and cultural differences.
Language	English
Publishing date	2024-02-29
Publishing country	New Zealand
Document type	Journal Article
ZDB-ID	2186503-6
ISSN	1178-2021 ; 1176-6328
ISSN (online)	1178-2021
ISSN	1176-6328
DOI	10.2147/NDT.S448853
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Article ; Online: Cerebral white matter changes in deficit and non-deficit subtypes of schizophrenia.

Tan, An Sen / Chew, Qian Hui / Sim, Kang

Journal of neural transmission (Vienna, Austria : 1996)

2020 Volume 127, Issue 7, Page(s) 1073–1079

Abstract: The considerable clinical heterogeneity in schizophrenia makes elucidation of its neurobiology challenging. Subtyping the disorder is one way to reduce this heterogeneity and deficit status is one such categorization based on the prominence of negative ... ...

Abstract	The considerable clinical heterogeneity in schizophrenia makes elucidation of its neurobiology challenging. Subtyping the disorder is one way to reduce this heterogeneity and deficit status is one such categorization based on the prominence of negative symptoms. We aimed to utilize diffusion tensor imaging (DTI) to identify unique white matter cerebral changes in deficit schizophrenia (DS) compared with non-deficit schizophrenia (NDS) and healthy controls (HC) in an Asian sample. A total of 289 subjects (111 HC, 133 NDS and 45 DS) underwent DTI and completed rating scales which assessed the severity of psychopathology, psychosocial functioning and premorbid intelligence.We found that DS patients had fractional anisotropy (FA) reductions in the Body of the Corpus Callosum (BCC) and right Posterior Thalamic Radiation (PTR) regions relative to HCs, and FA reductions in the right PTR relative to NDS patients. NDS patients had FA reductions of the BCC and right PTR relative to HCs. Binomial logistic regression analyses revealed that FA reductions of the right PTR FA was an independent predictor of deficit status. The identified brain white matter changes especially in the PTR relate to deficits of cognitive control and emotional awareness, which may underlie psychopathology associated with deficit status like inattention and affective blunting. These potential biomarkers of DS warrant further examination to determine their utility for monitoring illness progression and intervention response in schizophrenia.
MeSH term(s)	Anisotropy ; Brain/diagnostic imaging ; Diffusion Tensor Imaging ; Humans ; Schizophrenia/diagnostic imaging ; White Matter/diagnostic imaging
Language	English
Publishing date	2020-05-20
Publishing country	Austria
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	184163-4
ISSN	1435-1463 ; 0300-9564
ISSN (online)	1435-1463
ISSN	0300-9564
DOI	10.1007/s00702-020-02207-w
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Article ; Online: In Vitro Digestibility, Pasting and Thermal Properties, and Structure of Cross‐Linked Arenga pinnata (Wurmb.) Merr. Starch

Liu, Yuan‐Sen / Tan, Lin‐Bin / Li, Meng‐Yun / An, Feng‐Kun / Xue, Shan / Fu, Zhen

Starch ‐ Stärke. 2023 Jan., v. 75, no. 1-2 p.e2200112-

2023

Abstract: Sodium trimetaphosphate (STMP) cross‐linked Arenga pinnata starch (CLAPS) with different degrees of cross‐linking (0–97.79%) are prepared and their structural characteristics and physicochemical properties are evaluated. Cross‐linking does not ... ...

Abstract	Sodium trimetaphosphate (STMP) cross‐linked Arenga pinnata starch (CLAPS) with different degrees of cross‐linking (0–97.79%) are prepared and their structural characteristics and physicochemical properties are evaluated. Cross‐linking does not significantly change APS granular structure, but seems to lower the intensity of Maltese cross. With the cross‐linking degrees (CLD) increasing from 0.00% to 97.79%, the rapidly digestible starch (RDS) content of CLAPS is decreased from 66.50% to 16.34%, but the resistant starch (RS) content has the opposite trend and is increased from 29.87% to 82.77%. As the CLD increased, the solubility and swelling power of APS are significantly reduced from 10.24% and 16.52 g g⁻¹ to 1.02% and 4.60 g g⁻¹, respectively. Low CLD could increase viscosities of the APS, whereas high CLD significantly reduce the viscosities of the APS and the greater theCLD, the more obvious the reduction effect. Meanwhile, cross‐linked APS exhibits a high conclusion temperature and lower gelatinization enthalpy (ΔH). With the CLD increasing, short molecular ordered structure of CLAPS exhibits increasing trends. These results indicate that crosslinking with STMP can significantly alter digestibility and improve thermal stability of APS, which would provide a theoretical basis for development of APS products and could be used in low glycemic index (GI) foods.
Keywords	Arenga pinnata ; Silene chalcedonica ; crosslinking ; digestibility ; digestible carbohydrates ; enthalpy ; gelatinization ; glycemic index ; resistant starch ; sodium ; solubility ; temperature ; thermal stability
Language	English
Dates of publication	2023-01
Publishing place	John Wiley & Sons, Ltd
Document type	Article ; Online
Note	JOURNAL ARTICLE
ZDB-ID	241168-4
ISSN	0038-9056
ISSN	0038-9056
DOI	10.1002/star.202200112
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Comparison between non-pulmonary and pulmonary immune responses in a HIV decedent who succumbed to COVID-19.

Goh, Denise / Lee, Justina Nadia / Tien, Tracy / Lim, Jeffrey Chun Tatt / Lim, Sherlly / Tan, An Sen / Liu, Jin / Tan, Benedict / Yeong, Joe

Gut

2021 Volume 71, Issue 6, Page(s) 1231–1234

MeSH term(s)	COVID-19 ; HIV Infections ; Humans ; Immunity ; SARS-CoV-2
Language	English
Publishing date	2021-08-10
Publishing country	England
Document type	Letter ; Comment
ZDB-ID	80128-8
ISSN	1468-3288 ; 0017-5749
ISSN (online)	1468-3288
ISSN	0017-5749
DOI	10.1136/gutjnl-2021-324754
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Article ; Online: Clinical factors and mortality rates for non-traumatic upper extremity amputations.

Ting, Yong-Zheng Jonathan / Tan, An-Sen / Lai, Chi-Peng Timothy / Satku, Mala

The Journal of hand surgery, European volume

2021 Volume 47, Issue 3, Page(s) 314–320

Abstract: Non-traumatic upper extremity amputations are an increasing concern with the rising prevalence of diabetes mellitus. To ascertain the risk factors and mortality rates for these amputations, the demographic information, amputation history, comorbidities ... ...

Abstract	Non-traumatic upper extremity amputations are an increasing concern with the rising prevalence of diabetes mellitus. To ascertain the risk factors and mortality rates for these amputations, the demographic information, amputation history, comorbidities and clinical outcomes of 140 patients who underwent non-traumatic upper extremity amputations between 1 January 2004 and 31 October 2017 were studied. Correlations were assessed using Cochran-Armitage chi-squared tests, odds ratios and multivariate binomial logistic regression as appropriate. Diabetes mellitus, coronary artery disease, end-stage renal failure, peripheral arterial disease and prior lower extremity amputation were significant risk factors for multiple upper extremity amputations. One-year, 2-year and 5-year mortality rates were 12%, 15% and 38%, respectively, following first upper extremity amputation. The risk factors for upper extremity amputations correspond with those for lower extremity amputations, comprising mainly diabetes mellitus and its related comorbidities. The mortality rates for non-traumatic upper extremity amputations highlight their significant burden on patients.
MeSH term(s)	Amputation ; Humans ; Kidney Failure, Chronic ; Retrospective Studies ; Risk Factors ; Upper Extremity/surgery
Language	English
Publishing date	2021-09-02
Publishing country	England
Document type	Journal Article
ZDB-ID	2272801-6
ISSN	2043-6289 ; 1753-1934
ISSN (online)	2043-6289
ISSN	1753-1934
DOI	10.1177/17531934211042720
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Article: Manipulation of Skyrmion Motion Dynamics for Logical Device Application Mediated by Inhomogeneous Magnetic Anisotropy.

Lin, Jia-Qiang / Chen, Ji-Pei / Tan, Zhen-Yu / Chen, Yuan / Chen, Zhi-Feng / Li, Wen-An / Gao, Xing-Sen / Liu, Jun-Ming

Nanomaterials (Basel, Switzerland)

2022 Volume 12, Issue 2

Abstract: Magnetic skyrmions are promising potential information carriers for future spintronic devices owing to their nanoscale size, non-volatility and high mobility. In this work, we demonstrate the controlled manipulation of skyrmion motion and its ... ...

Abstract	Magnetic skyrmions are promising potential information carriers for future spintronic devices owing to their nanoscale size, non-volatility and high mobility. In this work, we demonstrate the controlled manipulation of skyrmion motion and its implementation in a new concept of racetrack logical device by introducing an inhomogeneous perpendicular magnetic anisotropy (PMA) via micromagnetic simulation. Here, the inhomogeneous PMA can be introduced by a capping nano-island that serves as a tunable potential barriers/well which can effectively modulate the size and shape of isolated skyrmion. Using the inhomogeneous PMA in skyrmion-based racetrack enables the manipulation of skyrmion motion behaviors, for instance, blocking, trapping or allowing passing the injected skyrmion. In addition, the skyrmion trapping operation can be further exploited in developing special designed racetrack devices with logic AND and NOT, wherein a set of logic AND operations can be realized via skyrmion-skyrmion repulsion between two skyrmions. These results indicate an effective method for tailoring the skyrmion structures and motion behaviors by using inhomogeneous PMA, which further provide a new pathway to all-electric skyrmion-based memory and logic devices.
Language	English
Publishing date	2022-01-16
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662255-5
ISSN	2079-4991
ISSN	2079-4991
DOI	10.3390/nano12020278
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