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  1. Book ; Thesis: Veränderung molekularer Fibrosemarker nach linksatrialem Vorhofohrverschluss

    Lustermann, Paul / Möbius-Winkler, Sven / Busch, Martin / Adams, Volker

    2023  

    Institution Friedrich-Schiller-Universität Jena
    Author's details von Paul Maximilian Lustermann
    Language German
    Size 73 Seiten, Illustrationen, Diagramme, 30 cm
    Publishing place Jena
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Friedrich-Schiller-Universität Jena, 2023
    Note Tag der Verteidigung: 07.11.2023
    HBZ-ID HT030626272
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: A Rare Cause of Intermittent Claudication: Persistent Sciatic Artery.

    Kretzschmar, Daniel / Möbius-Winkler, Sven

    Deutsches Arzteblatt international

    2021  Volume 118, Issue 21, Page(s) 362

    MeSH term(s) Abdomen ; Arteries ; Humans ; Intermittent Claudication/diagnosis ; Intermittent Claudication/etiology ; Leg ; Thorax
    Language English
    Publishing date 2021-07-11
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2406159-1
    ISSN 1866-0452 ; 1866-0452
    ISSN (online) 1866-0452
    ISSN 1866-0452
    DOI 10.3238/arztebl.m2021.0106
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Thesis: Randomisierter Vergleich zwischen perkutaner transluminaler koronarer Angioplastie mit Stentimplantation und körperlichem Ausdauertraining bei Patienten mit stabiler koronarer Herzerkrankung

    Möbius-Winkler, Sven

    2006  

    Author's details eingereicht von: Sven Möbius-Winkler
    Language German
    Size 75 Bl. : Ill., graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Leipzig, Univ., Diss., 2006
    HBZ-ID HT015633438
    Database Catalogue ZB MED Medicine, Health

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  4. Article ; Online: Indications for Duplex Sonography Should Be More Liberal.

    Kretzschmar, Daniel / Franz, Marcus / Möbius-Winkler, Sven

    Deutsches Arzteblatt international

    2021  Volume 118, Issue 26, Page(s) 464

    Language English
    Publishing date 2021-08-17
    Publishing country Germany
    Document type Letter
    ZDB-ID 2406159-1
    ISSN 1866-0452 ; 1866-0452
    ISSN (online) 1866-0452
    ISSN 1866-0452
    DOI 10.3238/arztebl.m2021.0189
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Successful Transcatheter Aortic Valve in JenaValve in Homograft Implantation in a 33-Year-Old Heart Failure Patient After Aortic and Mitral Valve Replacement Due to Severe Endocarditis 18 Years Ago.

    Mietz, Selma / Diab, Mahmoud / Bäz, Laura / Schulze, P Christian / Möbius-Winkler, Sven / Franz, Marcus

    Cardiovascular revascularization medicine : including molecular interventions

    2022  Volume 40S, Page(s) 322–324

    MeSH term(s) Adult ; Allografts/surgery ; Aortic Valve/diagnostic imaging ; Aortic Valve/surgery ; Aortic Valve Insufficiency/surgery ; Endocarditis/diagnostic imaging ; Endocarditis/surgery ; Heart Failure/diagnostic imaging ; Heart Failure/etiology ; Heart Failure/surgery ; Heart Valve Prosthesis ; Heart Valve Prosthesis Implantation/adverse effects ; Humans ; Mitral Valve/diagnostic imaging ; Mitral Valve/surgery ; Transcatheter Aortic Valve Replacement/adverse effects
    Language English
    Publishing date 2022-01-11
    Publishing country United States
    Document type Letter
    ZDB-ID 2212113-4
    ISSN 1878-0938 ; 1553-8389
    ISSN (online) 1878-0938
    ISSN 1553-8389
    DOI 10.1016/j.carrev.2022.01.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Concept and Design of a Novel Pulsatile Left Heart Assist Device-The PERKAT Left Ventricle System.

    Kretzschmar, Daniel / Möbius-Winkler, Sven / Schulze, P Christian / Ferrari, Markus W

    ASAIO journal (American Society for Artificial Internal Organs : 1992)

    2021  Volume 68, Issue 1, Page(s) 28–32

    Abstract: Cardiogenic shock is associated with high mortality. Patients often require temporary mechanical circulatory support. We aimed to develop a percutaneously implantable, assist device that unloads the left ventricle (LV) in a pulsatile way. The PERkutane ... ...

    Abstract Cardiogenic shock is associated with high mortality. Patients often require temporary mechanical circulatory support. We aimed to develop a percutaneously implantable, assist device that unloads the left ventricle (LV) in a pulsatile way. The PERkutane KATheter pump technologie (PERKAT LV) device consists of a nitinol pump chamber, which is covered by foils carrying outflow valves. A flexible tube with a pigtail-shaped tip and inflow holes represents the distal part of the pump. The system is designed for 16F percutaneous implantation. The nitinol chamber is placed in the descending aorta while the flexible tube bypasses aortic arch and ascending aorta with its tip in the LV. An intra-aortic balloon pump is placed into the chamber and connected to a console. Balloon deflation generates a blood flow from the LV into the pump chamber. During balloon inflation, blood leaves the system through the outflow foil valves in the descending aorta. Under different afterload settings using a 30 cc intra-aortic balloon pump and varying inflation/deflations rates, we recorded flow rates up to 3.0 L/min. Based on this, we believe that PERKAT LV is a promising approach for temporary LV support. The proposed design and its excellent performance give basis for in vivo tests in an animal model.
    MeSH term(s) Animals ; Equipment Design ; Heart Ventricles/surgery ; Heart-Assist Devices/adverse effects ; Hemodynamics ; Humans ; Intra-Aortic Balloon Pumping ; Pulsatile Flow ; Shock, Cardiogenic
    Language English
    Publishing date 2021-02-26
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 759982-1
    ISSN 1538-943X ; 0162-1432 ; 1058-2916
    ISSN (online) 1538-943X
    ISSN 0162-1432 ; 1058-2916
    DOI 10.1097/MAT.0000000000001397
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: A Very Rare Cause of Thrombotic Peripheral Occlusion.

    Kretzschmar, Daniel / Thieme, Marcus / Aschenbach, Rene / Schulze, P Christian / Möbius-Winkler, Sven

    The International journal of angiology : official publication of the International College of Angiology, Inc

    2022  Volume 32, Issue 1, Page(s) 75–80

    Abstract: A 45-year-old healthy woman presented with claudication of the right leg. The resting ankle-brachial index (ABI) was reduced to 0.6, and a duplex scan revealed an occlusion of the right popliteal artery. Angiography presented a patent superficial femoral ...

    Abstract A 45-year-old healthy woman presented with claudication of the right leg. The resting ankle-brachial index (ABI) was reduced to 0.6, and a duplex scan revealed an occlusion of the right popliteal artery. Angiography presented a patent superficial femoral artery that ends above the knee joint. Laterally, there was delayed retrograde contrast filling of the popliteal artery. After exploring the internal iliac artery, we crossed a thrombotic occlusion of a persisting sciatic artery (PSA). Local thrombolysis with recombinant tissue plasminogen activator (1 mg/h) was initiated. The Angiography 18 hours later showed a reduction of thrombotic material and relevant stenosis in the proximal part of the vessel. Residual thrombus and the stenosis were covered by two stentgrafts (Gore Viabahn Endoprosthesis) that were stabilized by an interwoven stent (Supera). Final angiography displayed a patent sciatic artery and a three-vessel run off. Postinterventional ABI was normalized to 1.0. The magnetic resonance imaging 6 days after the intervention demonstrated a patent PSA again and a normal blood flow on the left leg. A PSA should be included in the differential diagnosis of lower limb ischemia or suspected aneurysm formation. We demonstrated the feasibility of an interventional approach with an excellent outcome in this case.
    Language English
    Publishing date 2022-06-14
    Publishing country United States
    Document type Case Reports
    ZDB-ID 1144390-x
    ISSN 1061-1711
    ISSN 1061-1711
    DOI 10.1055/s-0042-1745850
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Intravascular Lithotripsy in Calcified Peripheral Lesions: Single-Center JEN-Experience.

    Aftanski, Pawel / Thieme, Marcus / Klein, Friederike / Schulze, P Christian / Möbius-Winkler, Sven / Kretzschmar, Daniel

    The International journal of angiology : official publication of the International College of Angiology, Inc

    2022  Volume 32, Issue 1, Page(s) 11–20

    Abstract: Peripheral artery disease (PAD) shows increasing need for revascularization therapy. Interventional success in calcified lesions is limited. Here, intravascular lithotripsy (IVL), modifying intimal and medial calcium, is a promising treatment approach. A ...

    Abstract Peripheral artery disease (PAD) shows increasing need for revascularization therapy. Interventional success in calcified lesions is limited. Here, intravascular lithotripsy (IVL), modifying intimal and medial calcium, is a promising treatment approach. A single-center, prospective all-comers registry for patients undergoing peripheral IVL was established to examine treatment success in PAD with severe vessel calcification. Periprocedural safety events as well as short-term and intermediate follow-up clinical data were evaluated. Between December 2018 and January 2021 all consecutive patients receiving peripheral lithotripsy at our center were analyzed. Clinical and angiographic data were evaluated. Angiographic images were analyzed using a semiautomatic software for quantitative vessel analysis. Eighty-five lesions in 61 limbs were treated with IVL in 51 patients presenting with Rutherford classes 2 to 5. Most lesions (68%) were localized in the superficial femoral artery. Mean calcified lesion length was 102.5 mm (10-390 mm), with a median peripheral arterial calcium score of 3, indicating a highly calcified status. In 58% of the patients, IVL was used as a stand-alone therapy. IVL resulted in a mean acute luminal gain of 2.6 ± 0.9 mm, resulting in stenosis reduction by 42.1 ± 15%. Mean ankle brachial index (ABI) improved significantly from 0.6 to 0.8 (
    Language English
    Publishing date 2022-08-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1144390-x
    ISSN 1061-1711
    ISSN 1061-1711
    DOI 10.1055/s-0042-1751229
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: The Safety and Efficacy of Ultrasound-Accelerated Catheter-Directed Thrombolysis in Patients with Intermediate-High-Risk Pulmonary Embolism: Bo-NE-Experience.

    Al-Terki, Hani / Mügge, Andreas / Gotzmann, Michael / Tiyerili, Vedat / Klein, Friederike / Franz, Marcus / Möbius-Winkler, Sven / Elhakim, Abdelrahman

    Journal of clinical medicine

    2023  Volume 12, Issue 10

    Abstract: Ultrasound-accelerated thrombolysis (USAT) is an advanced interventional therapy for patients with intermediate-high-risk pulmonary embolism (PE) who deteriorated on anticoagulation or for high-risk patients for whom systemic thrombolysis is ... ...

    Abstract Ultrasound-accelerated thrombolysis (USAT) is an advanced interventional therapy for patients with intermediate-high-risk pulmonary embolism (PE) who deteriorated on anticoagulation or for high-risk patients for whom systemic thrombolysis is contraindicated. The aim of this study is to investigate the safety and efficacy of this therapy with a focus on the improvement of vital signs and laboratory parameters. Seventy-nine patients with intermediate-high-risk PE were treated with USAT from August 2020 to November 2022. The therapy significantly decreased the mean RV/LV ratio from 1.2 ± 0.22 to 0.9 ± 0.2 (
    Language English
    Publishing date 2023-05-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12103459
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Use of Autotransfusion following Percutaneous Thrombectomy for Cardiogenic Shock Due to Pulmonary Embolism in a Single Session-A Case Report.

    Haertel, Franz / Baez, Laura / Franz, Marcus / Bogoviku, Jurgen / Klein, Friederike / Dannberg, Gudrun / Schulze, P Christian / Möbius-Winkler, Sven

    Diagnostics (Basel, Switzerland)

    2023  Volume 13, Issue 8

    Abstract: A 64-year-old male patient was admitted to the catheterization laboratory with a suspected myocardial infarction and in cardiogenic shock. Upon further investigation, a massive bilateral pulmonary embolism with signs of right heart dysfunction was ... ...

    Abstract A 64-year-old male patient was admitted to the catheterization laboratory with a suspected myocardial infarction and in cardiogenic shock. Upon further investigation, a massive bilateral pulmonary embolism with signs of right heart dysfunction was discovered, leading to a decision to perform a direct interventional treatment with a thrombectomy device for thrombus aspiration. The procedure was successful in removing almost the entirety of the thrombotic material from the pulmonary arteries. The patient's hemodynamics stabilized and oxygenation improved instantly. The procedure required a total of 18 aspiration cycles. Each aspiration contained approx. 60 mL blood amounting to a total of approx. 1080 mL of blood. During the procedure, a mechanical blood salvage system was used to resupply 50% of the blood via autotransfusion that would otherwise have been lost. The patient was transferred to the intensive care unit for post-interventional care and monitoring. A CT angiography of the pulmonary arteries after the procedure confirmed the presence of only minor residual thrombotic material. The patient's clinical, ECG, echocardiographic, and laboratory parameters returned to normal or near normal ranges. The patient was discharged shortly after in stable conditions on oral anticoagulation.
    Language English
    Publishing date 2023-04-11
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics13081392
    Database MEDical Literature Analysis and Retrieval System OnLINE

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